Prediction of type II diabetes mellitus based on demographic features by the use of machine learning classification algorithms — a study across Assam, India
ConclusionsThe study underscores lifestyle modifications for T2DM prevention, highlighting AI ’s potential in diagnosis and the impact of unhealthy habits on T2DM susceptibility. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 17, 2024 Category: Endocrinology Source Type: research

Assessing glycemic and weight-lowering potential of oral semaglutide in type 2 diabetes compared to other GLP-1 receptor agonists in Indian context
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 17, 2024 Category: Endocrinology Source Type: research

Effect of patient and wound characteristics on diabetic foot ulcer healing in phase 3 study of novel topical esmolol hydrochloride
ConclusionsNovel topical esmolol with SoC treatment exhibited significant DFU healing independent of patient-related factors including anemia, hypoalbuminemia, and poor glycemic control. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 15, 2024 Category: Endocrinology Source Type: research

Role of serum pentraxin-3 levels in patients with and without diabetic nephropathy
ConclusionThis study concludes that serum PTX3 can be used as a diagnostic marker for DN before the development of apparent chronic kidney disease and PTX3 was found to be a better marker than hs-CRP for diagnosing DN. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 15, 2024 Category: Endocrinology Source Type: research

Maternal and neonatal outcomes of deliveries at 39  weeks compared to deliveries at 40 weeks in pregnant women with diet controlled gestational diabetes mellitus
ConclusionThere were no statistically significant differences in maternal and neonatal adverse outcomes in women with diet-controlled gestational diabetes who delivered at 39  weeks compared to women who delivered at 40 weeks. However, the observed higher rate of shoulder dystocia and preeclampsia among women who delivered at 40 weeks might need to be investigated further in larger studies while it might indicate the need for iatrogenic intervention at 39 weeks. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 6, 2024 Category: Endocrinology Source Type: research

Unveiling the link between lifestyle risk factors and diabetic retinopathy
ConclusionWhile gender is beyond control, the other identified factors associated with DR can be managed through improved eating habits and regular exercise. Future investigations should prioritize exploring the collective influence of these factors on the development and progression of DR. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 6, 2024 Category: Endocrinology Source Type: research

Classification of diabetic retinopathy severity level using deep learning
ConclusionThe training and testing of our model are carried out on images from the Kaggle APTOS dataset, and this work can act as a base for the autonomous screening of DR. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 28, 2024 Category: Endocrinology Source Type: research

Quality of life assessment and therapeutic adherence in Mexican patients with type 2 diabetes
ConclusionsIf the TA of patients with T2DM increases, the overall QoL as well as the DRQoL will improve. Hence, these variables must be considered as therapeutic targets in clinical practice. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 27, 2024 Category: Endocrinology Source Type: research

Knowledge assessment of self-care activities of diabetes mellitus in a tertiary care hospital
ConclusionBy demonstrating a significant improvement in knowledge and observing good glycemic control in a substantial portion of participants, the study highlights its potential to empower individuals with T2DM. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 22, 2024 Category: Endocrinology Source Type: research

Mapping multimorbidity from diabetes mellitus and its association with depressive symptoms among older people of India: a cross-sectional study from a nationally representative survey
ConclusionHigher rate of multimorbidity among DM patients was recorded. Multimorbidity substantially increases the risk of acquiring depression. Timely identification and appropriate management multimorbidity of diabetes are important for reducing to incidence of depression and better quality of life and functionality. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 14, 2024 Category: Endocrinology Source Type: research

Cardiovascular autonomic neuropathy and charcot neuroarthropathy in type 2 diabetes: adding a new severity classification score
ConclusionsThere is a high prevalence of CAN in people with type 2 diabetes followed in a tertiary health service and the use of severity score may enable to differentiate people with or without CN. We suggest that this score could be used as a new tool in caring for people with diabetes to identify the most severe CAN. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 11, 2024 Category: Endocrinology Source Type: research

Self reported hypoglycemia in patients with type 2 diabetes mellitus taking oral anti-diabetics
ConclusionsLower prevalence of hypoglycemia in our study compared to other similar studies could be because of non-inclusion of patients on insulin in our study. High prevalence of multiple episodes justify the fact that hypoglycemia begets hypoglycemia. Hypoglycemia progressively increased as socioeconomic status changed from higher to lower, possibly due to non-availability of glucometer and lack of information. U-shaped correlation of hypoglycemic events was found with HbA1c levels. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 9, 2024 Category: Endocrinology Source Type: research

The relationship between glycated hemoglobin (HbA1c), hematocrit, mean platelet volume, total white blood cell counts, Visceral Adiposity Index, and Systematic Coronary Risk Evaluation 2 (SCORE2) in patients without diabetes
ConclusionA significant relationship was found between HbA1c and the current CVD risk score, SCORE2, in our patient group without DM. Our study is the first to examine this relationship in the literature. While no relationship was found between SCORE2 and body mass index (BMI), a significant relationship was found with the VAI. This indicates that CVD risk is more associated with visceral fat accumulation than total weight. Evaluating patients with normal BMI based on VAI will be beneficial in demonstrating CVD risk. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 7, 2024 Category: Endocrinology Source Type: research

Cluster analysis based on fasting and postprandial plasma glucose and insulin concentrations
ConclusionThe clustering analysis successfully differentiated individuals into distinct clusters based on their metabolic conditions, confirming that the approach effectively captured the underlying patterns in the plasma glucose and insulin data. Furthermore, despite not being a considered attribute, the varying age ranges observed within the clusters indicate that age may play a role in the development and progression of diabetes. Additionally, the fasting and postprandial associations in insulin and glucose levels exhibited greater strength in the cluster encompassing individuals with diabetes, where insulin production ...
Source: International Journal of Diabetes in Developing Countries - March 7, 2024 Category: Endocrinology Source Type: research

Effect of rosuvastatin on sortilin and fetuin-A in type 2 diabetic patients: a randomized controlled trial
ConclusionRosuvastatin co-treatment in T2DM patients improves glycemic control and aids in decreasing the atherogenic biomarkers sortilin and fetuin-A levels, so it can be considered tolerable and efficient in improving lipid profile and  atherogenic index.Trial registrationClinicalTrials.gov identifier (NCT number):  NCT03907423, (The registration date: April 9, 2019).https://clinicaltrials.gov/ct2/show/NCT03907423. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 2, 2024 Category: Endocrinology Source Type: research