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Assessment of DNA damage in children exposed to indoor tobacco smoke.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The present study is aimed to evaluate the possible DNA damage in children who are living with smoker parents. The tests were conducted by using alkaline comet assay, measured as a percentage of DNA damage in tail (%DNA(T)). The children that participated in the study were selected from the pediatric unit of a hospital in Istanbul, Turkey. %DNA(T) was significantly higher (p<0.01) in children who were exposed to indoor tobacco smoke (10.73+/-1.38) compared to the children in the control group (8.16+/-1.29). The number of cigarettes consumed by household members did not seem to affect the severity of the DNA damage. ...
Source: International Journal of Hygiene and Environmental health - November 2, 2009 Category: Environmental Health Authors: Beyoglu D, Ozkozaci T, Akici N, Omurtag GZ, Akici A, Ceran O, Sardas S Tags: Int J Hyg Environ Health Source Type: journals

Bisphenol A Workshop of the German Federal Environment Agency - March 30-31, 2009 Work Group Report: Public Health Issues of Bisphenol A.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19879190 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - October 28, 2009 Category: Environmental Health Authors: Gies A, Heinzow B, Dieter HH, Heindel J Tags: Int J Hyg Environ Health Source Type: journals

Challenge assay: A functional biomarker for exposure-induced DNA repair deficiency and for risk of cancer.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A variety of biomarkers have been used to monitor exposed populations to determine potential health hazards from their exposure to environmental toxic agents. However, the majority of these biomarkers have been focused onto the identification of biological damage from the exposure. Therefore, there is a need to develop functional biomarkers that can identify exposure-induced functional deficiencies. More importantly, these deficiencies should be positioned along pathways that are responsible for the development of specific diseases. One of such pathways belongs to the extensive and complex DNA-repair machinery. The mac...
Source: International Journal of Hygiene and Environmental health - October 6, 2009 Category: Environmental Health Authors: Au WW, Giri AK, Ruchirawat M Tags: Int J Hyg Environ Health Source Type: journals

Order of Merit to Professor Dr. Jürgen Angerer.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Order of Merit to Professor Dr. Jürgen Angerer. Int J Hyg Environ Health. 2009 Oct 7; Authors: Wilhelm M PMID: 19818683 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - October 6, 2009 Category: Environmental Health Authors: Wilhelm M Tags: Int J Hyg Environ Health Source Type: journals

Cancer mortality in a surveillance cohort of German males formerly exposed to asbestos.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The objective of this analysis was the estimation of the cancer risks of asbestos and asbestosis in a surveillance cohort of high-exposed German workers. A group of 576 asbestos workers was selected for high-resolution computer tomography of the chest in 1993-1997. A mortality follow-up was conducted through 2007. Standardised mortality ratios (SMRs) were calculated and Poisson regression was performed to assess mesothelioma risks. A high risk was observed for pleural mesothelioma (SMR 28.10, 95% CI 15.73-46.36) that decreased after cessation of exposure (RR 0.1; 95% CI 0.0-0.6 for >/=30 vs. <30 years after last expo...
Source: International Journal of Hygiene and Environmental health - September 24, 2009 Category: Environmental Health Authors: Pesch B, Taeger D, Johnen G, Gross IM, Weber DG, Gube M, Müller-Lux A, Heinze E, Wiethege T, Neumann V, Tannapfel A, Raithel HJ, Brüning T, Kraus T Tags: Int J Hyg Environ Health Source Type: journals

Outbreaks of Serratia marcescens in neonatal and pediatric intensive care units: Clinical aspects, risk factors and management.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The following recommendations are derived from a systematic analysis of 34 Serratia marcescens outbreaks described in 27 publications from neonatal and pediatric intensive care units (NICU, PICU), in which genotyping methods were used to confirm or exclude clonality. The clinical observation of two or more temporally related cases of nosocomial S. marcescens infection should raise the suspicion of an outbreak, particularly in the NICU or PICU setting. Since colonized or infected patients represent the most important reservoir for cross transmission, hygienic barrier precautions (contact isolation/cohortation, the use o...
Source: International Journal of Hygiene and Environmental health - September 24, 2009 Category: Environmental Health Authors: Voelz A, Müller A, Gillen J, Le C, Dresbach T, Engelhart S, Exner M, Bates CJ, Simon A Tags: Int J Hyg Environ Health Source Type: journals

Breast-milk levels of polybrominated diphenyl ether flame retardants in relation to women's age and pre-pregnant body mass index.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The aim of the present study was to determine associations between the occurrence of PBDEs in breast milk of women and their demographic parameters. Participants were randomly recruited from the general population in southern Taiwan. Thirty two breast milk samples were collected and subsequently 30 congeners of PBDEs were analyzed using a high resolution gas chromatograph with a high resolution mass spectrometer. The mean and median of SigmaPBDEs were 3.54 and 3.31ng/g lipid, respectively. SigmaPBDE levels in breast milk were not significantly correlated with age and pre-pregnant BMI of Taiwanese mothers. We did find, ...
Source: International Journal of Hygiene and Environmental health - September 22, 2009 Category: Environmental Health Authors: Koh TW, Chih-Cheng Chen S, Chang-Chien GP, Lin DY, Chen FA, Chao HR Tags: Int J Hyg Environ Health Source Type: journals

The capsaicin cough reflex in patients with symptoms elicited by odorous chemicals.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Patients with multiple chemical sensitivity and eczema patients with airway symptoms elicited by odorous chemicals have enhanced cough reflex to capsaicin when applying the tidal breathing method. The aims of the present study were to test whether the capsaicin induced cough reflex was enhanced when applying the single breath inhalation method in similar groups of patients with symptoms related to odorous chemicals e.g. other persons wearing of perfume; and to investigate to what extent the reporting of lower airway symptoms influenced the cough reflex. Sixteen patients fulfilling Cullen's criteria for multiple chemica...
Source: International Journal of Hygiene and Environmental health - September 18, 2009 Category: Environmental Health Authors: Holst H, Arendt-Nielsen L, Mosbech H, Vesterhauge S, Elberling J Tags: Int J Hyg Environ Health Source Type: journals

Feasibility of testing three salivary stress biomarkers in relation to naturalistic traffic noise exposure.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: There was a significant increase of sAA and sC concentrations after traffic noise exposure (p=0.045; p=0.01), whereas for sCgA this was not observed (p=0.48). Measuring of sAA and sC appear to be feasible to investigate direct stress effects in relation to naturalistic traffic noise exposure in a laboratory setup. Considering the small sample size of this pilot study, these observations need to be further proved in a larger explorative study. PMID: 19758843 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - September 13, 2009 Category: Environmental Health Authors: Wagner J, Cik M, Marth E, Santner BI, Gallasch E, Lackner A, Raggam RB Tags: Int J Hyg Environ Health Source Type: journals

Physicians appeals on the dangers of mobile communication - what is the evidence? Assessment of public health data.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In October 2002 German physicians appealed to persons in the field of health care, politicians and the public with "great concern" ("Freiburger Appell", "Appeal of Freiburg") claiming "soaring incidences of symptoms and diseases in the general population" to be causally related to the "commence of radio (wave) burden", i.e. due to mobile radio technology. This first example was followed by several further appeals published nationally and Europe-wide up until today. The aim of the present paper is an evaluation of the scientific literature and databases to check incidence and prevalence of symptoms and diseases stated i...
Source: International Journal of Hygiene and Environmental health - September 4, 2009 Category: Environmental Health Authors: Zur Nieden A, Dietz C, Eikmann T, Kiefer J, Herr CE Tags: Int J Hyg Environ Health Source Type: journals

Urinary di(2-ethylhexyl)phthalate (DEHP)-Metabolites and male human markers of reproductive function.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
DISCUSSION: Metabolites of DEHP and other phthalates analyzed in urine are very specific for determining recent internal phthalate exposure. According to our evaluation human reproductive parameters from semen analyses do not show significant associations with concentrations of DEHP metabolites determined in spot urine sampled at the day of andrological examination. PMID: 19733116 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - September 1, 2009 Category: Environmental Health Authors: Herr C, Zur Nieden A, Koch HM, Schuppe HC, Fieber C, Angerer J, Eikmann T, Stilianakis NI Tags: Int J Hyg Environ Health Source Type: journals

delta-Aminolevulinic acid dehydratase activitiy, urinary delta-aminolevulinic acid concentration and zinc protoporphyrin level among people with low level of lead exposure.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, ALAD possibly has a non-linear relation with low to moderate levels of PbB. At moderate levels of PbB, ZPP increases with increasing levels of PbB. ALAU is not suitable as an indicator for low levels of lead exposure. PMID: 19733117 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - September 1, 2009 Category: Environmental Health Authors: Wang Q, Zhao HH, Chen JW, Hao QL, Gu KD, Zhu YX, Zhou YK, Ye LX Tags: Int J Hyg Environ Health Source Type: journals

GerES IV: Phthalate metabolites and bisphenol A in urine of German children.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Urine samples from GerES IV were analysed for concentrations of the metabolites of DEHP (MEHP, 5OH-MEHP, 5oxo-MEHP, 5cx-MEPP, and 2cx-MMHP), DnBP and DiBP (MnBP and MiBP), BBzP (MBzP), DiNP (7OH-MMeOP, 7oxo-MMeOP and 7cx-MMeHP), and bisphenol A (BPA) to assess the exposure of German children on a representative basis. 600 morning urine samples had been randomly chosen from stored 1800 GerES IV samples originating from 3 to 14 year old children living in Germany. All metabolites could be detected in nearly all urine samples (N=599). Descriptive data analysis leads to mean concentrations of 5-OH-MEHP and 5-oxo-MEHP of 48...
Source: International Journal of Hygiene and Environmental health - August 31, 2009 Category: Environmental Health Authors: Becker K, Güen T, Seiwert M, Conrad A, Pick-Fuß H, Müller J, Wittassek M, Schulz C, Kolossa-Gehring M Tags: Int J Hyg Environ Health Source Type: journals

Genetic polymorphisms and expression of minisatellite mutations in a 3-generation population around the Semipalatinsk nuclear explosion test-site, Kazakhstan.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We have reported previously that a population near the Semipalatinsk nuclear explosion test site had significantly increased minisatellite mutations (MM), suggesting increased germ-line mutation rates from the exposure in 3 generations. We hypothesize that the MM can be used as a surrogate biomarker for functional genetic alterations, e.g. gene mutations and chromosome aberrations. Therefore, we have investigated the influence of polymorphisms in genes on the expression of MM in the same two populations (247 and 172 individuals, for exposed and control, respectively, in 3 generations), and their relationships with radi...
Source: International Journal of Hygiene and Environmental health - August 2, 2009 Category: Environmental Health Authors: Bolegenova NK, Bekmanov BO, Djansugurova LB, Bersimbaev RI, Salama SA, Au WW Tags: Int J Hyg Environ Health Source Type: journals

Biomonitoring of the di(2-ethylhexyl) phthalate metabolites mono(2-ethyl-5-hydroxyhexyl) phthalate and mono(2-ethyl-5-oxohexyl) phthalate in children and adults during the course of time and seasons.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study is aimed to assess the DEHP exposure in children and adults, to evaluate the intraindividual variability, the influence of seasons and to identify potential routes of intake. Urine samples were collected from 6 people (age 4-58) over 7 consecutive days 4-times during a year to test for seasonal factors. 5-OH-MEHP and 5-oxo-MEHP were quantified by GC-MS. Urine concentrations of both metabolites were highly correlated with each other. Both female subjects showed remarkably low and stable 5-OH-MEHP concentrations throughout the year (median </=64.1 and </=78.5mug/l). Also both male adults exhibited a low burd...
Source: International Journal of Hygiene and Environmental health - July 14, 2009 Category: Environmental Health Authors: Hildenbrand S, Wodarz R, Gabrio T, Volland G Tags: Int J Hyg Environ Health Source Type: journals

Revised and new reference values for environmental pollutants in urine or blood of children in Germany derived from the German Environmental Survey on Children 2003-2006 (GerES IV).email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Based on the representative data collection of the German Environmental Survey on Children 2003-2006 (GerES IV) the Human Biomonitoring Commission of the German Federal Environment Agency has updated the reference values for a comprehensive number of environmental pollutants in blood and urine of children in Germany. Reference values are statistically derived values that indicate the upper margin of background exposure to a given pollutant in a given population at a given time. They can be used as criteria to classify the measured values of individuals or population groups as being "elevated" or "not elevated". Since ...
Source: International Journal of Hygiene and Environmental health - July 6, 2009 Category: Environmental Health Authors: Schulz C, Angerer J, Ewers U, Heudorf U, Wilhelm M, Tags: Int J Hyg Environ Health Source Type: journals

Health risks of the occupational exposure to microbiological and chemical pollutants in a municipal waste organic fraction treatment plant.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Composting is a good alternative for the treatment of organic waste. However, an important amount of hazardous agents such as bioaerosols and volatile organic compounds may be released during the process. Therefore, the presence of microbiological and chemical pollutants emitted to air may mean a risk for the health of composting plants workers. We here report the results of an investigation aimed at evaluating the occupational exposure to chemical and biological agents for workers of an organic waste treatment facility (Montcada i Reixac, Catalonia, Spain). Total concentrations of bacteria and fungi (at 25 degrees C a...
Source: International Journal of Hygiene and Environmental health - July 5, 2009 Category: Environmental Health Authors: Nadal M, Inza I, Schuhmacher M, Figueras MJ, Domingo JL Tags: Int J Hyg Environ Health Source Type: journals

Personal PM(10) exposure in asthmatic adults in Padova, Italy: seasonal variability and factors affecting individual concentrations of particulate matter.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Personal exposure to PM(10) measured in different seasons in a sample of asthmatic subjects living in Padova (Northern Italy) was compared with simultaneously measured outdoor PM(10) concentrations. The specific contribution of ambient PM(10) and other factors to individual exposure was evaluated in one of the areas of Europe with the worst air pollution. Thirty-one asthmatic subjects (21 non-smokers and 10 smokers) carried personal PM(10) monitors for six 24-hr sessions, in different seasons of the year. Concomitant daily 24-hr ambient PM(10) concentrations were measured by air quality monitoring networks. A multivari...
Source: International Journal of Hygiene and Environmental health - June 29, 2009 Category: Environmental Health Authors: Scapellato ML, Canova C, de Simone A, Carrieri M, Maestrelli P, Simonato L, Bartolucci GB Tags: Int J Hyg Environ Health Source Type: journals

Hormone levels and sexual development in Flemish adolescents residing in areas differing in pollution pressure.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In 2002, the Centre for Environment and Health in Flanders, Belgium started a human biomonitoring program. For 1679 adolescents, residing in nine study areas with differing pollution pressure, hormone levels and the degree of sexual maturation were measured. Possible confounding effects of lifestyle and personal characteristics were taken into account. Participants from the nine different study areas had significantly different levels of sex hormones (total and free testosterone, oestradiol, aromatase, luteinizing hormone) and the thyroid hormone free triiodothyronine, after correction for confounders. Significantly hi...
Source: International Journal of Hygiene and Environmental health - June 19, 2009 Category: Environmental Health Authors: Croes K, Baeyens W, Bruckers L, Den Hond E, Koppen G, Nelen V, Van de Mieroop E, Keune H, Dhooge W, Schoeters G, Van Larebeke N Tags: Int J Hyg Environ Health Source Type: journals

A twin study of perfume-related respiratory symptoms.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Respiratory symptoms from environmental perfume exposure are main complaints in patients with multiple chemical sensitivities and often coincide with asthma and or eczema. In this population-based twin study we estimate the heritability of respiratory symptoms related to perfume and if co-occurrences of the symptoms in asthma, atopic dermatitis, hand eczema or contact allergy are influenced by environmental or genetic factors common with these diseases. In total 4,128 twin individuals (82%) responded to a questionnaire. The heritability of respiratory symptoms related to perfume is 0.35, 95%CI 0.14-0.54. Significant as...
Source: International Journal of Hygiene and Environmental health - June 4, 2009 Category: Environmental Health Authors: Elberling J, Lerbaek A, Kyvik KO, Hjelmborg J Tags: Int J Hyg Environ Health Source Type: journals

Assessment of polychlorinated biphenyl congeners, thyroid stimulating hormone, and free thyroxine among New York State anglers.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study considered associations between PCBs and thyroid function biomarkers in a specially selected subsample of participants from the New York State Angler Cohort Study, with the goal of hypotheses generation. Between 1995 and 1997, 38 subjects donated a blood specimen and completed a questionnaire. Sera were analyzed for 77 PCB congeners, beta-HCH, DDE, HCB, mirex, oxychlordane, and trans-nonachlor using GC-ECD, as well as for lipids components, thyroid stimulating hormone (TSH) and free thyroxine (FT(4)). A priori, the sum of all 77 measured PCB congeners, 27 individual PCB congeners with literature evidence for thy...
Source: International Journal of Hygiene and Environmental health - May 31, 2009 Category: Environmental Health Authors: Bloom MS, Vena JE, Olson JR, Kostyniak PJ Tags: Int J Hyg Environ Health Source Type: journals

Total blood mercury concentrations in the U.S. population: 1999-2006.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We describe the distribution and demographic characteristics of total blood Hg levels in the U.S. general population among persons ages 1 year and older who participated in the 2003-2006 National Health and Nutrition Examination Survey (NHANES). We also describe trends in the total blood Hg of children ages 1-5 (n=3456) and females ages 16-49 during 1999-2006 (n=7245). In the combined 2003-2006 survey periods, the geometric means for non-Hispanic blacks, 0.853mug/L (95% confidence interval [CI], 0.766-0.950mug/L), and non-Hispanic whites, 0.833mug/L (95% CI, 0.752-0.922mug/L), were higher than the geometric mean for Mexica...
Source: International Journal of Hygiene and Environmental health - May 27, 2009 Category: Environmental Health Authors: Caldwell KL, Mortensen ME, Jones RL, Caudill SP, Osterloh JD Tags: Int J Hyg Environ Health Source Type: journals

One-year follow-up of perfluorinated compounds in plasma of German residents from Arnsberg formerly exposed to PFOA-contaminated drinking water.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In Arnsberg, Sauerland area Germany, 40000 residents were exposed to PFOA-contaminated drinking water (500-640ng PFOA/l; May 2006). In July 2006, the PFOA-concentrations in drinking water were lowered significantly by activated charcoal filtering in the waterworks, mostly below the limit of detection (10ng/l). A first human biomonitoring study performed in autumn 2006 revealed that PFOA-concentrations in blood plasma of residents living in Arnsberg were 4.5-8.3 times higher than in the reference groups. One year after the first survey, all participants (2006: 164 mothers, 90 children, 101 men) were invited to take part...
Source: International Journal of Hygiene and Environmental health - May 20, 2009 Category: Environmental Health Authors: Hölzer J, Göen T, Rauchfuss K, Kraft M, Angerer J, Kleeschulte P, Wilhelm M Tags: Int J Hyg Environ Health Source Type: journals

Reply to the letter to the editor by A. Bauer, E. Schwarz and C. Mai "Environmental Medicine or Psychiatry?"email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19451032 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - May 15, 2009 Category: Environmental Health Authors: Eis D Tags: Int J Hyg Environ Health Source Type: journals

Fetal exposure to phthalates - a pilot study.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The fetus is considered to be the most sensitive stage of life to the potential developmental and reproductive toxicity of the phthalates. But, data on human fetal exposure to phthalates is still scarce. In this pilot study we collected 11 pairs of amniotic fluid (AF) and corresponding maternal urine (MU) samples during Caesarean section and analysed them for several phthalate metabolites by LC-MS/MS. In all AF samples, metabolites of di-n-butyl phthalate (DnBP), diisobutyl phthalate (DiBP), butylbenzyl phthalate (BBzP), di(2-ethylhexyl) phthalate (DEHP) were detectable. For the first time, we were able to detect also ...
Source: International Journal of Hygiene and Environmental health - May 4, 2009 Category: Environmental Health Authors: Wittassek M, Angerer J, Kolossa-Gehring M, Schäfer SD, Klockenbusch W, Dobler L, Günsel AK, Müller A, Wiesmüller GA Tags: Int J Hyg Environ Health Source Type: journals

Levels of metabolites of organophosphate pesticides, phthalates, and bisphenol A in pooled urine specimens from pregnant women participating in the Norwegian Mother and Child Cohort Study (MoBa).email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Concerns about reproductive and developmental health risks of exposure to organophosphate (OP) pesticides, phthalates, and bisphenol A (BPA) among the general population are increasing. Six dialkyl phosphate (DAP) metabolites, 3,5,6-trichloro-2-pyridinol (TCPy), BPA, and fourteen phthalate metabolites were measured in 10 pooled urine samples representing 110 pregnant women who participated in the Norwegian Mother and Child Birth Cohort (MoBa) study in 2004. Daily intakes were estimated from urinary data and compared with reference doses (RfDs) and daily tolerable intakes (TDIs). The MoBa women had a higher mean BPA con...
Source: International Journal of Hygiene and Environmental health - April 22, 2009 Category: Environmental Health Authors: Ye X, Pierik FH, Angerer J, Meltzer HM, Jaddoe VW, Tiemeier H, Hoppin JA, Longnecker MP Tags: Int J Hyg Environ Health Source Type: journals

The influence of air pollution during intrauterine development and early childhood on respiratory functions at later age.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: The research makes an attempt to provide evidence for the negative influence of high levels of air pollution during the intrauterine development and during early childhood, manifested by respiratory limitations at a later stage of childhood. It is known that the influence of air pollution with TSPM and SO(2) during the first 5 years of life is more important than that in intrauterine development for the respiratory functions. Data is lacking with concern to intrauterine programing of respiratory function. Further research is necessary for a detailed elucidation of the problem. PMID: 19398372 [PubMed - as su...
Source: International Journal of Hygiene and Environmental health - April 21, 2009 Category: Environmental Health Authors: Turnovska TH, Marinov BI Tags: Int J Hyg Environ Health Source Type: journals

Detection and toxicity assessment of nitrosamines migration from latex gloves in the Chinese market.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, in view of the high content of nitrosamines in latex gloves and the potential toxicity of nitrosamines migration from these gloves, it is suggested that both an effective and feasible detection method and prescribed limits should be imposed. PMID: 19395309 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 20, 2009 Category: Environmental Health Authors: Feng D, Wang H, Cheng X, Wang J, Ning L, Zhou Q, Zhou Y, Yang Q Tags: Int J Hyg Environ Health Source Type: journals

Standardization of whole blood assay for determination of pyrogenic activity in organic dust samples.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, cryo-preserved blood pools are suitable to standardize WBA. Combination of different outcome variables like IL-1beta and MCP-1 improve the characterization from the inflammatory potency of workplace related dust samples. PMID: 19395310 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 20, 2009 Category: Environmental Health Authors: Liebers V, Stubel H, Düser M, Brüning T, Raulf-Heimsoth M Tags: Int J Hyg Environ Health Source Type: journals

Use of biocidal products (insect sprays and electro-vaporizer) in indoor areas - Exposure scenarios and exposure modeling.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Five commercially available insect sprays were applied in a model room. Spraying was performed in accordance with the manufacturers' instructions and in an overdosed manner in order to simulate worst-case conditions or an unforeseeable misuse. In addition, we examined electro-vaporizers. The Respicon aerosol monitoring system was applied to determine inhalation exposure. During normal spraying (10 seconds) and during the following 2-3 minutes, exposure concentrations ranged from 70 to 590mug/m(3) for the pyrethroids tetramethrin, d-phenothrin, cyfluthrin, bioallethrin, and the pyrethrins. Calculated inhalable doses wer...
Source: International Journal of Hygiene and Environmental health - March 30, 2009 Category: Environmental Health Authors: Berger-Preiß E, Koch W, Gerling S, Kock H, Appel KE Tags: Int J Hyg Environ Health Source Type: journals

Safe drinking water and clean air: An experimental study evaluating the concept of combining household water treatment and indoor air improvement using the Water Disinfection Stove (WADIS).email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Indoor air pollution and unsafe water remain two of the most important environmental risk factors for the global burden of infectious diseases. Improved stoves and household water treatment (HWT) methods represent two of the most effective interventions to fight respiratory and diarrhoeal illnesses at household level. Since new improved stoves are highly accepted and HWT methods have their drawbacks regarding sustained use, combining the two interventions in one technical solution could result in notable positive convenience and health benefits. A WAter DIsinfection Stove (WADIS) based on a Lorena-stove design with a s...
Source: International Journal of Hygiene and Environmental health - February 19, 2009 Category: Environmental Health Authors: Christen A, Navarro CM, Mäusezahl D Tags: Int J Hyg Environ Health Source Type: journals

Bloodstream infections in a German paediatric oncology unit: Prolongation of inpatient treatment and additional costs.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this matched cohort study, clinical data from 43 paediatric cancer patients with bloodstream infection (BSI) were compared with 43 thoroughly matched control patients without BSI. BSI led to a median additional length of inpatient treatment of 12 days (IQR 8.5-16 days; P<0.001), accounting for median additional expenses of euro4400 (IQR, euro3145-5920) per case [6.970 US Dollar (IQR 4.938-9.294)]. Thus, BSI substantially increased financial resources required for inpatient treatment. These data compiled from a paediatric cancer unit may be utilized to estimate the cost-benefit ratio of targeted preventive measure...
Source: International Journal of Hygiene and Environmental health - February 19, 2009 Category: Environmental Health Authors: Biwersi C, Hepping N, Bode U, Fleischhack G, von Renesse A, Exner M, Engelhart S, Gieselmann B, Simon A Tags: Int J Hyg Environ Health Source Type: journals

Acrylamide as environmental noxious agent A health risk assessment for the general population based on the internal acrylamide burden.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The present population-based cross-sectional study in 1008 volunteers was aimed at quantifying the internal burden of acrylamide (AM) in the general population using hemoglobin adduct levels as biomarker of exposure. Based on these adduct levels the risk of (AM) related hazardous health effects in the general population is assessed. Hemoglobin adducts of acrylamide were detected in 999 out of 1008 analyzed blood samples (99.1%). Smoking can be regarded as a main source of overall acrylamide intake in persons without occupational exposure to acrylamide but a second main influence factor, i.e. food intake, is of environm...
Source: International Journal of Hygiene and Environmental health - February 19, 2009 Category: Environmental Health Authors: Kütting B, Schettgen T, Schwegler U, Fromme H, Uter W, Angerer J, Drexler H Tags: Int J Hyg Environ Health Source Type: journals

Mycobacterium phocaicum in therapy pool water.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We isolated Mycobacterium phocaicum, an emerging non-tuberculous species rarely identified in the respiratory tract and blood of patients, from the therapy pool water. Identification, confirmed by 16S rDNA and rpoB sequencing and phylogenetic analyses, disclosed a genotype 4. M. phocaicum should be added to the growing list of water-borne mycobacteria. PMID: 19201259 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - February 5, 2009 Category: Environmental Health Authors: Ben Salah I, Adékambi T, Drancourt M Tags: Int J Hyg Environ Health Source Type: journals

Environmental medicine or psychiatry?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19196550 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - February 2, 2009 Category: Environmental Health Authors: Bauer A, Schwarz E, Mai C Tags: Int J Hyg Environ Health Source Type: journals

Neurological risks associated with manganese exposure from welding operations - A literature review.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Exposure to manganese dusts and fumes may cause a clinical neurological syndrome called manganism. Welders are frequently exposed to manganese-containing fumes generated by electric arcs and thermal torches. This paper reviews studies on the association between exposure to such welding fumes and neurological disease. Using the IRSST expert panel criteria, 78 cases of probable/possible, and 19 additional cases of possible occupational manganism were identified in the literature among manganese-exposed workers involved in welding processes. Epidemiological evidence linking welding exposures to Parkinson's disease is stil...
Source: International Journal of Hygiene and Environmental health - January 30, 2009 Category: Environmental Health Authors: Flynn MR, Susi P Tags: Int J Hyg Environ Health Source Type: journals

Summary of the second meeting of the International Forum on Water Hygiene in Buildings (IFOWAHB) from 01 to 02.06.2007 in Stockholm.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19179112 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - January 27, 2009 Category: Environmental Health Authors: Exner M, Hartemann P Tags: Int J Hyg Environ Health Source Type: journals

Lead - Still a health threat for marksmen.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: While extensive public effort is undertaken to prevent the general population from environmental lead exposure this short report gives reason to keep recreational shooting in mind when facing elevated blood lead levels or clinical symptoms possibly associated with lead intoxication. PMID: 19135414 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - January 7, 2009 Category: Environmental Health Authors: Ochsmann E, Göen T, Schaller KH, Drexler H Tags: Int J Hyg Environ Health Source Type: journals

If there is an effect of lead exposure on malaria, then the activity of delta-aminolevulinate dehydratase (ALAD) may play a role, as ALAD is imported by the parasite from the host.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19062340 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - December 3, 2008 Category: Environmental Health Authors: Bergdahl IA Tags: Int J Hyg Environ Health Source Type: journals

Assessment of genotoxic risks in Croatian health care workers occupationally exposed to cytotoxic drugs: A multi-biomarker approach.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The aim of the present study was to evaluate genome damage induced in peripheral blood lymphocytes of Croatian health care workers occupationally exposed to cytotoxic drugs. A comprehensive multi-biomarker approach using the alkaline comet assay and cytogenetic endpoints (analysis of structural chromosome aberrations, SCE assay, lymphocyte proliferation kinetics and cytokinesis-block micronucleus assay) was employed. The study included two populations of subjects: 50 health care workers occupationally exposed to cytotoxic drugs and 50 control subjects matched in age, gender and smoking habit. An investigation regarding...
Source: International Journal of Hygiene and Environmental health - November 30, 2008 Category: Environmental Health Authors: Kopjar N, Garaj-Vrhovac V, Kašuba V, Rozgaj R, Ramić S, Pavlica V, Zelježić D Tags: Int J Hyg Environ Health Source Type: journals

Nephrotoxicity, neurotoxicity, and mercury exposure among children with and without dental amalgam fillings.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Although urinary mercury concentration was slightly elevated among children with amalgam fillings, we found no evidence of adverse effects on the outcomes evaluated. These results agree with those from recent trials in developed countries. PMID: 18996050 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - November 6, 2008 Category: Environmental Health Authors: Ye X, Qian H, Xu P, Zhu L, Longnecker MP, Fu H Tags: Int J Hyg Environ Health Source Type: journals

Comparative assessing for radiological, chemical, and physical exposures at the French uranium conversion plant: Is uranium the only stressor?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study presents the pattern of exposure to uranium and other occupational pollutants known to be potentially carcinogenic, mutagenic or toxic and used at the main uranium conversion plant in France. For different uranium compounds specified according to their solubility and purity, and 16 other categories of pollutants: chemicals, fibres, vapours, dust, and heat a time- and plant-specific job exposure matrix (JEM) was created covering the period 1960-2006. For 73 jobs and for each pollutant the amount and frequency of exposure were assessed on a four-level scale by different time periods. The JEM shows 73% sensitivity ...
Source: International Journal of Hygiene and Environmental health - October 30, 2008 Category: Environmental Health Authors: Guseva Canu I, Paquet F, Goldberg M, Auriol B, Bérard P, Collomb P, David JC, Molina G, Perez P, Tirmarche M Tags: Int J Hyg Environ Health Source Type: journals

Purchase of drinking water is associated with increased child morbidity and mortality among urban slum-dwelling families in Indonesia.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The objectives of our study were to characterize families who purchased drinking water and to examine the relation between purchasing drinking water and child morbidity and mortality in urban slums of Indonesia, using data collected between 1999 and 2003. Of 143,126 families, 46.8% purchased inexpensive drinking water from street vendors, 47.4% did not purchase water, i.e., had running or spring/well water within household, and 5.8% purchased more expensive water in the previous 7 days. Families that purchased inexpensive drinking water had less educated parents, a more crowded household, a father who smoked, and lower soc...
Source: International Journal of Hygiene and Environmental health - October 29, 2008 Category: Environmental Health Authors: Semba RD, de Pee S, Kraemer K, Sun K, Thorne-Lyman A, Moench-Pfanner R, Sari M, Akhter N, Bloem MW Tags: Int J Hyg Environ Health Source Type: journals

Comparison of different medical cases in urinary arsenic speciation by fast HPLC-ICP-MS.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The inorganic arsenic species As(III), As(V) and the organic species methylarsonate (MMA(V)), dimethylarsinate (DMA(V)) and arsenobetaine (AsB) were determined in human urine by a fast anion exchange HPLC-ICP-MS method, which was developed for clinical laboratories with high sample throughput. This paper compares typical chromatograms of the arsenic species in urine samples collected in different medical cases, for example, for the non-exposed population, for environmentally (plant protectants) and occupationally (glass manufacture) exposed persons, for a person after a failed suicide attempt with As(2)O(3) and for per...
Source: International Journal of Hygiene and Environmental health - October 21, 2008 Category: Environmental Health Authors: Heitland P, Köster HD Tags: Int J Hyg Environ Health Source Type: journals

Pooled analysis of NAT2 genotypes as risk factors for asbestos-related malignant mesothelioma.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Malignant mesothelioma (MM) is a rare and aggressive tumor of the pleura. The most important causal factor for the development of MM is occupational exposure to asbestos. Different lines of evidence suggest a role of genetic background in MM development, as for other cancers. Two published studies observed an association between MM and N-acetyl-transferase 2 (NAT2) polymorphisms. First, a Finnish study observed that the NAT2 slow acetylator phenotype was associated with an increased risk of MM. Conversely, MM risk was higher in Italian subjects carrying the NAT2 fast acetylator genotypes. The conflicting results obtain...
Source: International Journal of Hygiene and Environmental health - September 30, 2008 Category: Environmental Health Authors: Betti M, Neri M, Ferrante D, Landi S, Biava A, Gemignani F, Bertolotti M, Mirabelli D, Padoan M, Ugolini D, Botta M, Bonassi S, Magnani C, Dianzani I Tags: Int J Hyg Environ Health Source Type: journals

Pesticide sales and adult male cancer mortality in Brazil.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study, we evaluated the degree of correlation between pesticide sales in 1985 in eleven Brazilian states and cancer mortality rates during 1996-1998. Information of all cancer deaths occurred in men 30-69 years old from 1996 to 1998 were collected from National Mortality System. Single and multiple linear regression coefficients were obtained to assess the relationship between per capita sales of pesticides in 1985, specific-site cancer mortality rates (prostate, soft tissue, larynx, leukemia, lip, esophagus, lung, pancreas, bladder, liver, testis, stomach, brain, non-Hodgkin's lymphoma, and multiple myeloma) durin...
Source: International Journal of Hygiene and Environmental health - September 30, 2008 Category: Environmental Health Authors: Chrisman JD, Koifman S, de Novaes Sarcinelli P, Moreira JC, Koifman RJ, Meyer A Tags: Int J Hyg Environ Health Source Type: journals

Screening of estrogen-like activity of mineral water stored in PET bottles.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Bottled mineral water consumption is steadily rising in the World. Italy is the largest natural mineral water consumer in Western Europe, about 200L per capita per annum. Recently, research has concentrated upon emerging toxicological problems such as the presence in drinking water of substances which interfere with the function of the endocrine system; defined as endocrine disruptors (EDs). The aim of this study was to assess the risk of exposure of the population to chemicals with estrogen-like activity through mineral water consumption by monitoring the presence of estrogenic compounds in mineral water bottled in po...
Source: International Journal of Hygiene and Environmental health - September 30, 2008 Category: Environmental Health Authors: Pinto B, Reali D Tags: Int J Hyg Environ Health Source Type: journals

Mycotoxins and child health: The need for health risk assessment.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The occurrences of mycotoxins as food contaminants in different localities particularly in developing countries and the inevitable exposure of populations and children to these toxins with probable adverse outcomes need be scientifically and systematically assessed. Health risk assessment developed in the 1980s is separate from risk management, both with risk communication form the risk analysis framework adopted by the World Health Organization. The process contributes increasingly to policy development, public health decision making, the establishment of mycotoxin regulations and research planning. However, the exerc...
Source: International Journal of Hygiene and Environmental health - September 18, 2008 Category: Environmental Health Authors: Sherif SO, Salama EE, Abdel-Wahhab MA Tags: Int J Hyg Environ Health Source Type: journals

The emission potential of different land use patterns for the occurrence of coliphages in surface water.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Different land use patterns were investigated for their potential as non-point sources of coliphage emissions into surface waters. Water samples were taken regularly at five locations in the upper reaches of the river Swist, Germany. Samples of surface and subsurface run-off were taken within the same catchment area after rainfall events using a newly developed device that made it possible to collect current concentrations of the effluent compounds. The water quality was examined for the occurrence of somatic coliphages and F(+)-specific RNA-bacteriophages as well as for various bacteria over the period of a hydrologic...
Source: International Journal of Hygiene and Environmental health - September 17, 2008 Category: Environmental Health Authors: Franke C, Rechenburg A, Baumanns S, Willkomm M, Christoffels E, Exner M, Kistemann T Tags: Int J Hyg Environ Health Source Type: journals

Reply to the letter to the editor by J.G. Dórea "Health hazard for infants: Breast-milk mercury or non-breastfeeding? A dilemma for mothers exposed to mercury vapours"email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Reply to the letter to the editor by J.G. Dórea "Health hazard for infants: Breast-milk mercury or non-breastfeeding? A dilemma for mothers exposed to mercury vapours" Int J Hyg Environ Health. 2008 Sep 12; Authors: Bose-O'Reilly S, Drasch G, Lettmeier B, Roider G, Siebert U PMID: 18790670 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - September 12, 2008 Category: Environmental Health Authors: Bose-O'Reilly S, Drasch G, Lettmeier B, Roider G, Siebert U Tags: Int J Hyg Environ Health Source Type: journals