International Journal of STD and AIDS
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Current management of syphilis infection
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Vera, J H, Parkes, R, Goldmeier, D Tags: Letters to the Editor Source Type: journals
Condom use and prevalence of sexually transmitted infection among performers in the adult entertainment industry
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Hill, S C, King, G, Smith, A Tags: Letters to the Editor Source Type: journals
Use of two HIV-POCT tests to identify false reactives
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Teague, A, Rossi, M, Gilmour, C, Watson, L, Atkins, M, McOwan, A Tags: Letters to the Editor Source Type: journals
Hepatitis C screening in genitourinary clinic attendees
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Kerr, R S, Fernando, I, Templeton, K, Flynn, B Tags: Letters to the Editor Source Type: journals
Convictions for sexual transmission of diseases do not enhance authority
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Phillips, M Tags: Letters to the Editor Source Type: journals
Sex toy hygiene
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: O'Connor, C, O'Connor, M B, Clancy, J, Ryan, A Tags: Letters to the Editor Source Type: journals
Increasing HIV testing in general practice: brief advice seems to work
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Phillips, M, Lazaro, N, Sweeney, J, Hesketh, L, Lamden, K Tags: Letters to the Editor Source Type: journals
Intestinal spirochetosis as a cause of chronic diarrhoea in patients with HIV infection: case report and review of the literature
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We describe a 77-year-old patient with HIV infection suffering from chronic diarrhoea whose colonoscopy findings showed normal appearance mucosa and tissue samples revealed the presence of a dense layer of spirochetes attached to the apical cell membrane. A literature search from 1996 to April 2009 identified 19 additional cases of intestinal spirochetosis in patients with HIV infection. Analysis of cases showed that intestinal spirochetosis causes chronic diarrhoea in men who have sex with men (92% of patients with reported HIV infection risk factors) who are not severely immunosuppressed (70% with CD4 lymphocyte cells &g...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Ena, J, Simon-Aylon, A, Pasquau, F Tags: Case reports Source Type: journals
Haemorrhagic transformation of cerebral infarction in an AIDS patient - thrombophaelia screen essential!
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We report a case of an AIDS patient who presented with acute hemiparesis. He was severely immunosuppressed. Computed tomography of the head confirmed cerebral infarction with haemorrhagic transformation. He had no known risk factors apart from being severely immunocompromised and had high anticardiolipin antibodies and low free protein S. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Yoganathan, K, Benton, A Tags: Case reports Source Type: journals
Chain of evidence in sexual assault cases
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Chain of evidence (COE) sampling is a legal concept demonstrating the journey of a sample from origin to court. Positive sexually transmitted infection (STI) results may have importance in criminal proceedings and require a demonstrated COE for them to be used as admissible evidence. A retrospective case-notes review of female sexual assault patients was carried out to review COE sampling in two clinics. Three hundred and eighteen patients underwent sexual health screening and COE sampling was indicated in 58 (18%). COE sampling was carried out in 44 (92%) of 48 indicated cases at the Haven (a dedicated sexual assault cent...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Lowe, S M, Rahman, N, Forster, G Tags: Audit reports Source Type: journals
Microscopy detection of rectal gonorrhoea in asymptomatic men
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This audit aimed to determine the usefulness of microscopy to detect presumptive rectal gonorrhoea (GC) infection in asymptomatic men. We retrospectively audited more than 400 male patients attending a London genitourinary medicine clinic from January 2005 to March 2007 who tested rectal culture positive for Neisseria gonorrhoeae and compared this with the microscopy detection rate. In total, 123/423 (29%) of culture positive samples were microscopy positive. Of those that tested microscopy negative (300/423), 64 (21%) were symptomatic and 236 (79%) asymptomatic. In addition, a time and motion study examined 81 rectal slid...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Forni, J, Miles, K, Hamill, M Tags: Audit reports Source Type: journals
Concentrated and linked epidemics of both HSV-2 and HIV-1/HIV-2 infections in Senegal: public health impacts of the spread of HIV
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In conclusion, HIV epidemic remains concentrated in high-risk groups of the Senegalese population, such as the FSW population in which the seroprevalence of HSV-2 infection is very high. Intervention against STI including HSV-2 is urgently needed to prevent the spreading of HIV epidemic. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Kane, C T., Diawara, S, Ndiaye, H D, Diallo, P A N, Wade, A S, Diallo, A G, Belec, L, Mboup, S Tags: Original research articles Source Type: journals
Indeterminate rapid HIV-1 test results among antenatal and postnatal mothers
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In conclusion, indeterminate rapid HIV-1 test results are more common in the antenatal period and appropriate safeguards to confirm HIV-1 infection status should be implemented in antenatal programmes. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Matemo, D, Kinuthia, J, John, F, Chung, M, Farquhar, C, John-Stewart, G, Kiarie, J Tags: Original research articles Source Type: journals
Genital herpes: an Internet-based risk survey
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Genital herpes is one of the most common sexually transmitted infections worldwide. We established a web-based survey to determine risk for genital herpes and encourage people to attend for herpes simplex virus testing. A survey was established on the Australian Herpes Management Forum (AHMF) website, consisting of 16 demographic and sexual health-related questions. Each question carried a numerical risk-weighting based on epidemiological data; the higher the overall score, the greater the risk of herpes. To determine how representative our sample was in relation to age and sex, we compared our survey with Australian Censu...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Mindel, A, McHugh, L, Christie, E, Chung, C, Berger, T Tags: Original research articles Source Type: journals
Access to dental care for HIV patients: does it matter and does discrimination exist?
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A number of surveys highlight a shortage of dentists in the UK. There is also evidence of discrimination against those with HIV reported within the dental profession and service users. We decided to assess the extent of this problem in our HIV outpatients by conducting a cross-sectional survey, asking them to complete a questionnaire exploring issues related to dental care access, and using clients attending the routine genitourinary (GU) medicine outpatient clinic as controls. A total of 241 outpatients completed the survey, of whom 51 (21%) were HIV patients. Significantly, more HIV patients reported difficulty registeri...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Levett, T, Slide, C, Mallick, F, Lau, R Tags: Original research articles Source Type: journals
Bacterial vaginosis: a cause of infertility?
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Bacterial vaginosis (BV) is a common disorder of the genital tract in women characterized by an alteration of the normal acidic lactobacilli-predominant vaginal ecosystem to a vaginal environment dominated by Gardnerella vaginalis, mycoplasma species and anaerobes, with an increase in pH. The present study evaluated whether BV is associated with reproductive complications in women. BV was screened with a Gram stain of vaginal smear and interpretation was done using the Nugent score. Wet mount and polymerase chain reaction were used to screen other infections. Among 510 enrolled women, 72 (14.1%) had BV. Statistical analysi...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Mania-Pramanik, J, Kerkar, S C, Salvi, V S Tags: Original research articles Source Type: journals
Does the addition of a urine testing kit to use of contact slips increase the partner notification rates for genital chlamydial infection?
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This study was designed to determine whether a better partner notification outcome could be achieved by giving female index patients with genital chlamydial infection a home sampling kit instead of contact slips only. Two hundred female patients attending a sexually transmitted infection clinic with a diagnosis of genital chlamydial infection were randomized to either the conventional partner notification arm using contact slips (swab testing arm) or the urine sampling kit for partner notification arm (urine testing arm). There were no differences in the number of partners treated per index case (0.67 in the swab testing g...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Apoola, A, Beardsley, J Tags: Original research articles Source Type: journals
Mucocutaneous manifestations in 150 HIV-infected Indian patients and their relationship with CD4 lymphocyte counts
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Mucocutaneous findings in 150 HIV+ve cases (F, 79; M, 71) were evaluated over a one-year period. Mucocutaneous manifestations were seen in 96% with 2.9 mean number of dermatoses and mean cluster of differentiation (CD4) count of 196.33 cells/mm3. The highest number of mean dermatoses, 3.29, was seen in individuals with severe immunosuppression. The most common mucocutaneous manifestation seen was candidiasis (35.33%), followed by seborrhoeic dermatitis (31.33%), oral pigmentation (29.33%), xerosis/ichthyosis (22.67%), pyodermas (22%), periodontitis (17.33%) and nail pigmentation (16.67%). Patient stratification according t...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Sud, N, Shanker, V, Sharma, A, Sharma, N L, Gupta, M Tags: Original research articles Source Type: journals
Pearly penile papules regress in older patients and with circumcision
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In conclusion, PPP disappear with age, and any PPP in patients >50 years are less marked than those in patients <25 years. Patients should be advised accordingly. PPP are less prevalent in circumcised men. Patients could be advised to wear the foreskin rolled back – this may maximize exposure of the coronal area to normal abrasion, which may hasten PPP regression. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Agha, K, Alderson, S, Samraj, S, Cottam, A, Merry, C, Lee, V, Patel, R Tags: Original research articles Source Type: journals
HIV testing men in the antenatal setting: understanding male non-disclosure
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We examined male HIV disclosure in couples who attended a Nairobi antenatal clinic (ANC), had individual HIV testing, and were counselled to disclose to their partner. At two-week follow-up, men and women independently reported HIV disclosure. Of 2104 women, 1993 requested partner attendance; 313 male partners came, of whom 183 chose individual HIV testing. Of 106 couples who followed up, 93% of both partners reported disclosure by women versus 71% by men (P < 0.0001); 27% of men reported disclosure while their female partner reported not knowing partner HIV status. In these couples, male ANC HIV testing did not result ...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Katz, D A, Kiarie, J N, John-Stewart, G C, Richardson, B A, John, F N, Farquhar, C Tags: Original research articles Source Type: journals
Emotional intimacy predicts condom use: findings in a group at high sexually transmitted disease risk
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In conclusion, these data were opposite to those of previous studies, which showed an inverse relationship between condom use and emotional intimacy. We hypothesize that in a high-risk environment, people exert more effort in protecting those they feel closer to. These data suggest a need to further explore the complex relationship between emotional intimacy and condom use. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Damani, R, Ross, M W, Aral, S O, Berman, S, St Lawrence, J, Williams, M L Tags: Original research articles Source Type: journals
Sexual behaviour, condom use and rates of sexually transmitted infections in HIV clinic attendees in South East London
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The aim of this study was to examine sexual behaviour, condom use and rates of sexually transmitted infections (STIs) among attendees at a dedicated on-site STI clinic at a South London HIV centre. Data were prospectively collected by using a nurse-completed questionnaire. Ninety-eight percent of women reported one or no sexual partners in the preceding three months, whereas 57% of men who have sex with men (MSM) reported two or more partners. Only 28% of women, 53% of heterosexual men and 29% of MSM always used a condom for vaginal or anal intercourse. Positive STI diagnoses were found in 17.5% of women, 20% of heterosexu...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Hamlyn, E, Welz, T, Rebaudengo, S, Simms, H, Poulton, M Tags: Original research articles Source Type: journals
Nurse-led sexually transmitted disease clinics: staff perceptions concerning the quality of the service
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In conclusion, there was a high level of staff satisfaction with the service. Nurse-led STI clinics may be a useful adjunct to existing STI facilities. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Mindel, A, Fennema, J S A, Christie, E, van Leent, E Tags: Original research articles Source Type: journals
Shortening the voiding interval for men having chlamydia nucleic acid amplification tests
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Male patients are assessed for a sexually transmitted infection provided a considerable length of time has elapsed since last micturition. The current availability of highly sensitive nucleic acid amplification tests (NAATs) for Chlamydia trachomatis (CT) and Neisseria gonorrhoea such as APTIMA Combo2 (AC2) led us to investigate the impact of voiding interval on the positivity of urine tests for CT. Male patients attending a genitourinary medicine clinic at high clinical risk for CT infection and known CT positives returning for treatment were included. Two first-void urine (FVU) specimens were collected: the first sample ...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Mathew, T, O'Mahony, C, Mallinson, H Tags: Short report Source Type: journals
Destigmatizing genitourinary medicine and sexually transmitted infections in the UK
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Sexually transmitted infections (STIs) and the clinics patients attend for STI management remain stigmatized. Although emphasizing sexual intercourse rather than sexual behaviour as an important factor in STI acquisition may help to destigmatize STIs, this will require a change in the national mindset. A different approach entails destigmatizing genitourinary (GU) medicine/sexual health thereby normalizing the conditions managed in these settings. This may be helped by emphasizing the non-STI-related aspect of GU medicine and by considering a change in terminology that removes the focus from STIs and attempts to absorb the...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Sonnex, C Tags: Review Source Type: journals
Assessing training in sexual dysfunction for genitourinary medicine registrars
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The training programme for specialist registrars in genitourinary medicine (GU) lists sexual dysfunction (SD) as ‘beyond essential, core curriculum’ despite many GU medicine clinics offering this service. A cross-sectional study was performed of all trainees on the British Association for Sexual Health and HIV mailing list. Data collected included frequency of clinics attended and involvement, any training and interest in future training. A total of 39/76 (51%) responses were received. In total, 20/39 (51%) work in departments with no SD clinic provision, and 12/39 have had some training in SD. In routine GU me...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Emerson, C, Goldmeier, D, Green, P, on behalf of BASHH Special Interest Group for Sexual Dysfunction Tags: Training Source Type: journals
Questioning the value of screening for gonorrhoea in symptomless heterosexual men
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These two papers discuss whether gonorrhoea screening of asymptomatic heterosexual men with no contact history should continue in UK genitourinary medicine clinics. Currently, most clinics routinely test all attenders. This requires an estimated 330,000 tests annually to detect 915 positives (1 in 361). The benefits to these patients are uncertain but the costs are huge and could fund currently unprovided services such as oral contraceptive provision or HIV testing before terminations of pregnancy. However stopping testing would deny individuals the reassurance they seek, prevent early detection of outbreaks and fail to de...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Pittrof, R, Hitchings, S, FitzGerald, M, Pittrof, R, Hitchings, S, FitzGerald, M Tags: Debate Source Type: journals
Response to Crum-Cianflone et al., Syphilitic hepatitis among HIV-infected patients
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Doyle, R J, Desai, M, White, J Tags: Letters to the Editor Source Type: journals
Oral-anal intercourse and sexual transmission of Enterobius vermicularis; do we need to screen for other intestinal parasites?
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Abdolrasouli, A, Hart, J Tags: Letters to the Editor Source Type: journals
Obstructive endo-bronchial pseudotumour due to herpes simplex type 2 infection in an HIV-infected man
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We report a 31-year-old man with an obstructive bronchial lesion due to herpes simplex type 2 infection, who responded promptly to endoscopic resection and oral treatment with acyclovir. Exophytic lesions of the respiratory tract are rare, potentially life-threatening, but readily treated complication of herpes simplex virus infection in HIV-infected individuals. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Plowman, G M, Watson, M W, D'Souza, H, Thomas, M G Tags: Case reports Source Type: journals
Preliminary HIV test result disclosure: lessons we can learn
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This article covers important lessons learnt from the case. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Tayal, S, Chawla, G Tags: Case reports Source Type: journals
Successful treatment of a large Buschke-Lowenstein tumour with chemo-radiotherapy
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We report the case of a patient with a large Buschke–Lowenstein tumour which had previously recurred following local excision. A preferred treatment modality for this rare variant of human papillomavirus has not been clearly defined. Treatment with chemo-radiotherapy in this case resulted in complete resolution of the disease without the need for further surgical intervention. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Armstrong, N, Foley, G, Wilson, J, Finan, P, Sebag-Montefiore, D Tags: Case reports Source Type: journals
Bronzino's 'Allegory of Venus and Cupid': an exemplary image for contemporary sexual health promotion?
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Recent sexual health promotion strategies have veered between a negative emphasis on the deleterious consequences of sexually transmitted infections, and a more positive, eroticized approach to safer sex. The differences in approach are starkly reflected in the images chosen to illustrate them. We note that there are problems with both approaches. The main purpose of this review is to demonstrate how this dichotomy was transcended by the sixteenth century Florentine Mannerist painter, Agnolo Bronzino, in his allegory on syphilis. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Porter, S, Kelly, C Tags: Art in medicine Source Type: journals
The evolution of an integrated sexual health service
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In conclusion, the role of community services increased during the evolution of the integrated sexual health network, although the majority of STIs were diagnosed within in the GU medicine clinic. Male screens accounted for one-third of those performed. A gap in male attendances remains despite the plurality of services. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Creighton, S, Apea, V Tags: Original research articles Source Type: journals
What do patients want most from sexual health services?
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This study sought to determine what patients valued most when attending an integrated sexual health clinic. During February 2009, 252 patients attending a sexual health clinic in outer London completed an anonymous questionnaire. The questionnaire asked for their views on different aspects of sexual health care. The results showed that the most highly valued aspects of care were confidentiality (18.47% of points allocated) followed by speed of service (13.1%) and rapid test results (12.12%). These aspects were more important than being seen within 48 hours (7.78%), technical expertise (6.26%) or other patient-centred aspec...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Hitchings, S, Allotey, J, Pittrof, R Tags: Original research articles Source Type: journals
Further observations, mainly serological, on a cohort of women with or without pelvic inflammatory disease
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An analysis was undertaken of data pertaining to over 100 women with lower abdominal pain who were laparoscoped. Prior to laparoscopy, 11 of the women were considered to almost certainly have salpingitis, of whom six (55%) had salpingitis at laparoscopy; 17 to probably have salpingitis, of whom six (35%) did; 28 to possibly have salpingitis, of whom five (18%) did; and 56 to be very unlikely to have salpingitis, of whom five (9%) did. Of the 22 women who had salpingitis at laparoscopy, 14 (64%) had a Chlamydia trachomatis IgG antibody titre of ≥1:128 and might reasonably be regarded as having chlamydial disease on this ...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Taylor-Robinson, D, Stacey, C M, Jensen, J S, Thomas, B J, Munday, P E Tags: Original research articles Source Type: journals
Profile of direct walk-in and referred clients attending Integrated Counselling and Testing Centre
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The HIV pandemic has had a profound impact on the health and economic conditions of individuals, and people living with HIV/AIDS are faced with the task of maintaining optimal health status despite an increasing insult to their immune status. The aim of the present study was to study the profile of direct walk-in and referred patients attending the Integrated Counselling and Testing Centre (ICTC) of a tertiary care hospital, which may provide important clues to understanding the epidemiology of the disease in a particular region. The study included all the attendees of the ICTC referred from the hospital or direct walk-in ...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Kashyap, B, Bhalla, P, Sharma, A, Saini, S Tags: Original research articles Source Type: journals
Factors associated with unprotected anal intercourse between HIV-positive men and regular male partners in a Sydney cohort
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Blood plasma HIV-RNA load (BPVL) is the strongest predictor of HIV-1 transmission during sex. Unprotected anal intercourse (UAI) is the highest risk activity for transmission among men who have sex with men (MSM). Awareness of BPVL may influence rates of UAI. We assessed whether optimism towards antiretroviral therapy (ART) and/or biomedical factors influenced sexual activities with regular partners. Questionnaires were administered to 109 HIV-positive MSM participating in a cross-sectional study of BPVL and seminal viral load. The survey assessed HIV transmission beliefs and sexual practices with regular male partners in ...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Begley, K, Chan, D J, Jeganathan, S, Batterham, M, Smith, D E Tags: Original research articles Source Type: journals
What service users want: a new clinic results service. Can we satisfy both patients' needs and wants?
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Many clinics still have a ‘no news is good news’ (NNIGN) policy for clinic results. We asked our service users their preferences for obtaining results. We also designed a new clinic results service. Patients were invited to complete a service evaluation questionnaire. They were given nine options for obtaining results and asked to rate acceptability on a 1–9 scale (unacceptable to acceptable). Completed questionnaires were compared with the actual method they chose to obtain results for that visit. In all, 1000 questionnaires (561 females, 439 males) were completed. Average acceptability score was highest...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Challenor, R, Deegan, S Tags: Original research articles Source Type: journals
The psychological impact caused by genital warts: has the Department of Health's choice of vaccination missed the opportunity to prevent such morbidity?
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This study evaluated the psychological impact caused by genital warts and whether this altered over time. Eighty-four patients with genital warts and a group of 28 appropriately matched volunteers from the local general population were recruited. The patients were divided into three groups of 28 according to the Health Protection Agency classification codes for genital warts. A comprehensive health questionnaire was completed by all participants. Patients with first attack genital warts experienced significantly more distress, anxiety and depression and were less satisfied with their lives than all the other groups. They a...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Lawrence, S, Walzman, M, Sheppard, S, Natin, D Tags: Original research articles Source Type: journals
A randomized double-blind comparison of moxifloxacin and doxycycline/metronidazole/ciprofloxacin in the treatment of acute, uncomplicated pelvic inflammatory disease
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This multicentre, double-blind study was undertaken to demonstrate non-inferiority of once-daily oral moxifloxacin compared with combination therapy in the management of acute, uncomplicated pelvic inflammatory disease (PID). Women aged ≥18 years with PID were randomized to receive moxifloxacin (400 mg once daily) for 14 days or comparator treatment (doxycycline [100 mg twice daily] plus metronidazole [400 mg three times daily] for 14 days, plus one single 500-mg ciprofloxacin dose). Of the 434 valid per protocol (PP) patients, the overall clinical success rates at 2–14 days post-therapy were 96.6% (moxifloxacin) ...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Heystek, M, Ross, J D C, for the PID Study Group Tags: Original research articles Source Type: journals
Cardiovascular risk factors and ultrasound evaluation of carotid atherosclerosis in patients with HIV-1 infection
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A cross-sectional study was performed to evaluate classical risk factors for cardiovascular diseases and subclinical atherosclerosis by carotid ultrasonography in HIV-positive subjects, naïve or treated with antiretroviral agents. A total of 66 patients were enrolled into the study: 21 subjects were naïve to all antiretroviral agents (group A) and 45 patients were treated with antiretroviral therapy for greater double equals36 months (group B). The prevalence of carotid plaques was significantly higher in group B than in group A (44.7% versus 0%; P = 0.014). In group B, patients with high 10-year risk of coronary...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Calza, L, Verucchi, G, Pocaterra, D, Pavoni, M, Alfieri, A, Cicognani, A, Manfredi, R, Serra, C, Chiodo, F Tags: Original research articles Source Type: journals
Concurrent sexual partnerships among individuals in HIV sero-discordant heterosexual couples
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In conclusion, more frequent HIV testing may complement increased attention to communication, disclosure and condom use in this population that is especially vulnerable to acquiring and transmitting HIV infection. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Eaton, A, van Der Straten, A Tags: Original research articles Source Type: journals
A review of cervical cytology in genitourinary medicine clinics in England between 1997 and 2008
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The current cervical screening guidelines lay the duty of care of women under 25 years of age on genitourinary (GU) medicine clinics. To date there has not been an extensive review of cervical cytology results sourced from GU medicine departments. We reviewed the annual reports of the cervical screening programme, with their extensive and comparative data, including records of cervical cytology from GU medicne. There is a clear and progressive trend of rising percentages of ‘severe dyskaryosis’ in laboratory reported GU medicine cervical smears. The trend and observations indicate that GU medicine physicians sh...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Markos, A R Tags: Miscellaneous Source Type: journals
Review of drug treatment for female sexual dysfunction
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Female sexual dysfunction (FSD) incorporates various sexual disorders including hypoactive sexual desire disorder, sexual arousal disorder, orgasmic and sexual pain disorders. Although many strategies have been formulated for the treatment of male sexual problems, FSD remains an area that warrants further research and trial studies to identify the most efficacious treatment options. Research has highlighted numerous pharmacological interventions that have been trialled and found to exhibit positive effects. These include hormonal therapies, prostaglandins, dopaminergic agonists, phosphodiesterase type-5 (PDE-5) inhibitors ...
Source: International Journal of STD and AIDS - October 8, 2009 Category: Global & Universal Authors: Wylie, K, Malik, F Tags: Review Source Type: journals
Feasibility of primary HIV care in a Thai tertiary care centre
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - August 25, 2009 Category: Global & Universal Authors: Khawcharoenporn, T, Apisarnthanarak, A, Kitkungvan, D, Laowansiri, P, Mundy, L M Tags: Letter to the Editor Source Type: journals
Threadworm: an infrequent clinical finding in a genitourinary medicine clinic attendee presenting with ano-genital irritation
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - August 25, 2009 Category: Global & Universal Authors: Waugh, M A Tags: Letter to the Editor Source Type: journals
Asymptomatic non-specific urethritis: making observations but drawing the wrong conclusion
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - August 25, 2009 Category: Global & Universal Authors: Markos, A Tags: Letter to the Editor Source Type: journals
Effect of ureaplasmas on male fertility: a continuing enigma
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - August 25, 2009 Category: Global & Universal Authors: Taylor-Robinson, D Tags: Letters to the Editor Source Type: journals
Erratum - Correction of date
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(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - August 25, 2009 Category: Global & Universal Tags: Erratum Source Type: journals
