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Migration of reticulated hyaluronic acid implant [SK-GEL] following deep sclerectomyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A new complication after deep sclerectomy with implant is presented as a case report. A 42-year-old male with uncontrolled primary open-angle glaucoma underwent nonpenetrating deep sclerectomy (NPDS) with an SK-GEL implant in his left eye. Two months after surgery the implant was noted to migrate into the subconjunctival space. Seven months later the implant was stable in the new position without complication. Implant migration into the subconjunctival space is a possible complication of NPDS. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10792-009-9325-8Authors Saleh A. Al Obeida...
Source: International Ophthalmology - October 21, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Optical coherence tomography-based intravitreal ranibizumab (Lucentis) for neovascular age-related macular degenerationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To evaluate optical coherence tomography (OCT)-based intravitreal ranibizumab treatment for neovascular age-related macular degeneration (AMD), the charts of consecutive patients who received intravitreal ranibizumab for subfoveal choroidal neovascularization due to AMD were retrospectively reviewed. Patients with less than 6 months follow-up were excluded. OCT was performed at baseline and at monthly intervals for induction therapy. Injections were given monthly until no improvement was observed between successive OCTs. In the maintenance period, reinjections were performed for any recurrence ...
Source: International Ophthalmology - September 15, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Association of systemic steroids and mycophenolate mofetil as rescue therapy for uveitic choroidal neovascularization unresponsive to the traditional immunesuppressants: interventional case seriesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To study the efficacy of systemic steroids (SS) associated with mycophenolate mofetil (MMF) for the control of juxta/sub-foveal uveitic choroidal neovascularization (CNV) unresponsive to the traditional immunosuppressive agents. Patients with juxta/sub-foveal uveitic CNV unresponsive to the traditional immunesuppressive drugs were treated with SS and MMF. The study was designed as a prospective, consecutive, open-label, interventional case series. Visual gain and loss were defined as improving or worsening of two or more lines of best-corrected visual acuity (BCVA), respectively. CNV size outcome wa...
Source: International Ophthalmology - September 3, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Non-vitrectomizing surgery for idiopathic macular pucker using a 25-gauge synergetics high-flow infusion with a 27-gauge light (Photon™ II, Synergetics USA, Inc.)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To describe a case of macular pucker treated by non-vitrectomizing vitreoretinal surgery using a 25-gauge high-flow infusion cannula with a 27-gauge illumination source (Photon™ II; both from Synergetics USA Inc., O’Fallon, MO). A 42-year-old man complaining of visual reduction and metamorphopsia was referred to the Vitreoretinal Surgery Unit, where he underwent full ophthalmic examination. Best corrected visual acuity (BCVA) at baseline was 0.5 in the left eye (LE) and 1.0 in the right eye. He was diagnosed with epiretinal membrane (ERM) in the LE. The surgical procedure envisaged two-port scle...
Source: International Ophthalmology - September 3, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Orbital solitary fibrous tumor. Another rare case from AfricaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Solitary fibrous tumor (SFT) of the orbit, initially thought to be rare, is being increasingly documented in the medical literature. We here present the case of a 37-year-old Nigerian man who presented with left sided painless, vision-sparing proptosis. Cranial computed tomography scan showed a globular, left medial, orbital extraconal mass. The mass was excised, en bloc, via a medial orbitotomy procedure aided by left ethmoidectomy. Surgery was uncomplicated and histology of the excised tissue was reported as compatible with SFT. There was also a strong and diffuse immunostaining with CD 34. At 6-m...
Source: International Ophthalmology - September 3, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Highly viscous fluid in macular holesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a highly viscous fluid inside the macular hole and document that disappearance of this viscous fluid results in concentric macular hole closure. Twenty eyes of 20 patients (64.9 ± 6.9, 54–73 years) with macular holes who underwent 25-gauge (25G) transconjunctival vitrectomy were studied. Macular holes were Gass stage 2 in 4 eyes, stage 3 in 11, and stage 4 in 5. After peeling the internal limiting membrane around the macular hole, fluid was aspirated from the edge of the macular hole using a 25G soft tip cannula while performing fluid-air replacement. During aspiration, a highly viscous fl...
Source: International Ophthalmology - August 28, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Novel infectious agents causing uveitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In any patient with uveitis, an infectious cause should be ruled out first. The differential diagnosis includes multiple well-known diseases including herpes, syphilis, toxoplasmosis, tuberculosis, bartonellosis, Lyme disease, and others. However, clinician should be aware of emerging infectious agents as potential causes of systemic illness and also intraocular inflammation. Air travel, immigration, and globalization of business have overturned traditional pattern of geographic distribution of infectious diseases, and therefore one should work locally but think globally. This review recapitulates t...
Source: International Ophthalmology - August 27, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Foveal neovascularisation in diabetic retinopathy: case report and review of literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To report a rare case of unilateral foveal neovascularisation in an asymptomatic patient with 15-year history of insulin-dependent diabetes mellitus and bilateral proliferative diabetic retinopathy and diabetic macular edema. Fundus fluorescein angiography and optical coherence tomography scan confirmed the presence of foveal neovascularisation. There was complete regression of the foveal neovascularisation after pan retinal laser photocoagulation. We review the literature on foveal neovascularisation in diabetic retinopathy and propose a possible pathogenic mechanism for development of foveal neova...
Source: International Ophthalmology - July 28, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Bevacizumab versus ranibizumab in the treatment of exudative age-related macular degenerationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The purpose of this article is to describe functional and morphological short-term results in patients with exudative age-related macular degeneration (AMD) of all subtypes, treated with intravitreal bevacizumab versus intravitreal ranibizumab. This was a retrospective case-controlled series of 30 patients treated with intravitreal bevacizumab and 30 patients treated with intravitreal ranibizumab for exudative AMD. All patients received three initial injections every 4 weeks. Best corrected visual acuity (BCVA) as well as greatest linear dimension (GLD) of the CNV in fluorescein angiography and...
Source: International Ophthalmology - July 26, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Mitomycin C in the treatment of a Schneiderian (inverted) papilloma of the lacrimal sacEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Schneiderian papillomas are benign tumours, with an aggressive nature. A case with a recurrent Schneiderian papilloma of the nasolacrimal sac, who underwent an external dacryocystorhinostomy (DCR) with irrigation of the nasolacrimal system with 0.02% mitomycin C (MMC), is presented at 18 months follow-up. External DCR using MMC, as an adjuvant therapy, is a novel approach to the treatment of Schneiderian papilloma of the nasolacrimal tract. It allows preservation of function, compared with the conventional treatment of dacryocystectomy. Content Type Journal ArticleCategory Case ReportDOI 10....
Source: International Ophthalmology - July 25, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Matrix metalloproteinase-9 expression in retinal ganglion cell layer and effect of topically applied brimonidine tartrate 0.2% therapy on this expression in an endothelin-1-induced optic nerve ischemia modelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The purpose of this research is to investigate the expression of matrix metalloproteinase-9 (MMP-9) in retinal ganglion cells (RGC) and the impact of topically applied brimonidine tartrate 0.2% (BMD) on this expression in an endothelin-1 (ET-1)-induced chronic optic nerve (ON) ischemia model of rabbit. Osmotically driven minipumps were implanted in one eye of 16 New Zealand albino rabbits to deliver ET-1 at the constant rate of 0.5 μl/h for 2 weeks. ET-1 was given with (group 3) and without topical BMD therapy (group 1). Groups 2 and 4 were taken as controls. MMP-9 expression by immunohis...
Source: International Ophthalmology - July 25, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Descemet’s stripping endothelial keratoplasty: is it an option for congenital hereditary endothelial dystrophy?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The purpose of this study was to report our experience of an attempted Descemet’s stripping automated endothelial keratoplasty (DSAEK) in a patient with congenital hereditary endothelial dystrophy (CHED). A 7-year-old boy presented with the complaints of decreased vision in his right eye. The left eye had undergone penetrating keratoplasty at the age of 5 years. He was diagnosed as a case of CHED, and a DSAEK was planned for him. Due to technical difficulties during Descemet’s membrane scoring and stripping and poor visualization, the procedure had to be abandoned and converted to a full th...
Source: International Ophthalmology - July 22, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Sympathetic ophthalmia following vitreoretinal surgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective is to discuss the characteristics of three patients who developed sympathetic ophthalmia following vitreoretinal surgery. The first case was a 29-year-old man who underwent placement of an encircling band, pars plana vitrectomy, foreign body removal, endolaser photocoagulation, transscleral cryotherapy, and silicone oil injection due to a retained foreign body 3 months after a corneoscleral rupture repair. He experienced visual loss in the fellow eye 2 months after the vitrectomy. An extensive exudative detachment was detected in the fellow eye. Sympathetic ophthalmia was diagnosed and systemic ...
Source: International Ophthalmology - July 9, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Nd:YAG laser goniopuncture in viscocanalostomy: penetration in non-penetrating glaucoma surgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective was to evaluate the results of Nd:YAG laser goniopuncture after viscocanalostomy and to investigate the rate of penetration in non-penetrating surgery. Results of viscocanalostomy and incidence of goniopuncture were retrospectively investigated in 33 eyes of 33 patients. Success was defined as an intraocular pressure (IOP) below 19 mmHg with an at least 30% decrease compared to the last preoperative measurement. General success rates after a mean follow-up of 33.5 ± 11.3 months were 79 and 46%, with and without medications, respectively. Mean IOP levels, which were 37.7 ± 9...
Source: International Ophthalmology - May 29, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Fungal keratitis associated with ocular rosaceaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In order to report fungal keratitis in patients of ocular rosacea, a retrospective review of all cases of fungal keratitis was undertaken. Cases in which ocular rosacea coexisted were identified and included in the study. The clinical course of patients thus identified was studied from the medical records and outcomes were evaluated. A total of three cases of fungal keratitis with coexisting ocular rosacea were identified. All three patients were known cases of acne rosacea with an intermittent, irregular treatment for the same. Previous history of contact lens use, ocular surgery or trauma was not ...
Source: International Ophthalmology - May 24, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Hydrogen peroxide-induced cellular apoptosis is mediated by TGF-β2 signaling pathway in cultured human lens epithelial cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to investigate the signaling characteristics of transforming growth factor-β2 (TGF-β2) and the Smads (Caenorhabditis elegans, Sma; Drosophila mothers against dpp, Mad) signal pathway of cellular apoptosis induced by hydrogen peroxide with human lens epithelial cells (HLECs). HLECs were starved for 24 h before exposure to 0.1 μmol/ml of hydrogen peroxide in the presence and in the absence of 0.01 μg/ml of AF-302-NA, a monoclonal anti-TGF-β2 neutralization antibody. Non-stimulated cells served as controls. Cell apoptosis was examined by in situ immunocytochemistry using...
Source: International Ophthalmology - May 15, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Subfoveal choroidal neovascularization in a patient with hemicentral vein occlusionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of a 69-year-old male patient who came to our attention for macular edema in hemiretinal vein occlusion. Fluorescein angiogram showed presence of venous collaterals, but the pattern of the edema was atypical; optical coherence tomography (OCT) and indocyanine green angiography (ICG) were used to confirm the diagnosis of CNV. A chorio-retinal shunt was demonstrated. The autofluorescence technique was used to predict the risk of CNV in the fellow eye. PDT was performed twice, but after the second cycle, patient developed choroidal ischemia and the visual outcomes were poor. The temporal course of CNV, t...
Source: International Ophthalmology - May 9, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Laser flare photometry: a noninvasive, objective, and quantitative method to measure intraocular inflammationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Aqueous flare and cells are the two inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood–ocular barriers. When examined with the slit lamp, measurement of intraocular inflammation remains subjective with considerable intra- and interobserver variations. Laser flare cell photometry is an objective quantitative method that enables accurate measurement of these parameters with very high reproducibility. Laser flare photometry allows detection of subclinical alterations in the blood–ocular barriers, identifying subtle pathological changes that could not hav...
Source: International Ophthalmology - May 9, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Endogenous Candida albicans infection causing subretinal abscessEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion A subretinal abscess, previously reported in Nocardia, Pseudomonas, Staphylococcus, and Aspergillus infection cases, can also occur in patients infected with Candida. Therefore, Candida infection should be considered as a potential cause of subretinal abscess in organ transplant recipients. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10792-009-9304-0Authors Toshikatsu Kaburaki, The University of Tokyo Graduate School of Medicine Department of Ophthalmology 7-3-1 Hongo, Bunkyo-ku Tokyo 113-0033 JapanMitsuko Takamoto, The University of Tokyo Graduate School of Medicine Department of Ophthalmo...
Source: International Ophthalmology - April 10, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Fusarium keratitis and endophthalmitis associated with lens contact wearEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Fusarium endophtalmitis can result in a devastating disease with a poor visual outcome. An initial antifungal dual therapy may control the infection. In case of failure, an early keratoplasty may be mandatory. For contact lens wearers, education on sanitary good practice is necessary to avoid new epidemics in the future. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10792-008-9290-7Authors Julia Proença-Pina, University Paris XI Department of Ophthalmology, Bicêtre University Hospital, APHP Le Kremlin Bicêtre Paris FranceIsabelle Ssi Yan Kai, University Paris XI Department of Ophthalmol...
Source: International Ophthalmology - April 10, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Chiasmal compression misdiagnosed as normal-tension glaucoma: can we avoid the pitfalls?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present three patients in whom the initial diagnosis of NTG was eventually revealed to be chiasmal compression secondary to a pituitary tumour. Case 1: a 79-year-old woman was treated for NTG for several months before a bitemporal haemianopia developed and imaging showed a pituitary tumour. Case 2: an 83-year-old man was treated for NTG while a magnetic resonance imaging (MRI) scan was requested routinely. This subsequently revealed a pituitary tumour. Case 3: a 52-year-old man with left inferior arcuate visual field loss plus disc pallor was treated for NTG. His visual field deteriorated over 8 years, despite...
Source: International Ophthalmology - April 8, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Incidence and prognosis of ocular hypertension secondary to viral uveitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract This retrospective study was designed to estimate the cumulative incidence of glaucoma in viral uveitis. Seventy-six consecutive patients with viral stromal keratouveitis were divided into two groups according to the etiologic agents herpes simplex virus (HSV) keratouveitis (n = 58) and herpes zoster virus (HZV) keratouveitis (n = 18). The groups were evaluated for the incidence and prognosis of ocular hypertension. Etiologic agents were determined with the help of clinical observation supported by the polymerase chain reaction (PCR) of aqueous humor. All patients received oral a...
Source: International Ophthalmology - April 3, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Management of congenital glaucoma in neurofibromatosis type 1: a report of two casesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present two patients with neurofibromatosis type 1 and associated congenital glaucoma. In case 1, the glaucoma was present at birth, and was the first symptom of the disease. It was surgically treated by means of an Ahmed glaucoma valve implantation, with good intraocular pressure (IOP) control after 13 months of follow-up. In case 2, the glaucoma appeared at 5 months old, and a trabeculectomy was initially performed; it failed 2 years later and an Ahmed glaucoma valve was then implanted, with adequate IOP control after 7 years of follow-up. Both children were males, and in both ca...
Source: International Ophthalmology - April 2, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Frequency of diabetic retinopathy in the adult population in China: the Beijing Eye Study 2001Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To evaluate the prevalence of diabetic retinopathy and its impact on visual impairment in China. The Beijing Eye Study, a population-based study on inhabitants aged 40+ years in rural and urban regions of Greater Beijing included 4,439 subjects out of 5,324 subjects invited to participate. Fundus photographs of the worse eye per subject were graded using the early treatment of diabetic retinopathy study criteria. The minimum criterion for diagnosis of diabetic retinopathy was the presence of at least one microaneurysm. Gradable fundus photographs were available for 4,391 (98.9%) subjects. Diabetic ...
Source: International Ophthalmology - February 17, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Risk factors for ethambutol optic toxicityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Given an understanding of the risk factors for ethambutol optic toxicity, there exists a rationale for an optimization of ethambutol dosing protocols that can maximize the therapeutic effect while minimizing the incidence of optic toxicity. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-009-9293-zAuthors Katherine Anne Talbert Estlin, University of Southern California Doheny Eye Institute, Keck School of Medicine 1450 San Pablo Street Los Angeles CA 90033 USAAlfredo A. Sadun, University of Southern California Doheny Eye Institute, Keck School of Medicine 1450 San Pablo Street Los An...
Source: International Ophthalmology - February 11, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Immune recovery uveitis associated with highly active antiretroviral therapy in a patient with CMV retinitis and AIDS despite a low CD4+ T cell count: case report and a review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract An unusual case of CMV retinitis and AIDS who developed immune recovery uveitis (IRU) despite a low CD4+ T cell count achieved during HAART is reported. A 36-year-old female complained of blurred vision in both eyes six months after initiation of anti-CMV retinitis therapy and HAART. Ocular examination revealed a substantial intraocular inflammation causing a dense vitreous haze and frosted branch angiitis. Consecutive CD4+ T cell counts were 20 cells/mm3 or less and plasma HIV mRNA was undetectable. The laboratory test for Cytomegalovirus was positive whereas those for infections known to cause uve...
Source: International Ophthalmology - February 7, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Eye injury (ocular trauma) in southern Turkey: epidemiology, ocular survival, and visual outcomeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Eye injury is still a common and avoidable cause of blindness. Our findings suggest that any person in the population can be subject to ocular trauma at any time. Prognosis might be challenging. Education, attention, and safety precautions would help in reducing ocular morbidity. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-009-9300-4Authors Merih Soylu, University of Çukurova, School of Medicine Department of Ophthalmology Adana TurkeySelcuk Sizmaz, Baskent University, School of Medicine Department of Ophthalmology Ankara TurkeySibel Cayli, University of Çukurova, School of Med...
Source: International Ophthalmology - February 4, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

A clinical approach to the diagnosis of retinal vasculitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Retinal vasculitis is a sight-threatening inflammatory eye condition that involves the retinal vessels. Detection of retinal vasculitis is made clinically, and is confirmed with the help of fundus fluorescein angiography. Active vascular disease is characterized by exudates around retinal vessels resulting in white sheathing or cuffing of the affected vessels. In this review, a practical approach to the diagnosis of retinal vasculitis is discussed based on ophthalmoscopic and fundus fluorescein angiographic findings. Content Type Journal ArticleDOI 10.1007/s10792-009-9301-3Authors Ahmed M. Abu ...
Source: International Ophthalmology - February 4, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Morphological changes in the retinal pigment epithelium on spectral-domain OCT in the unaffected eyes with idiopathic central serous chorioretinopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions 3D single-layer RPE map showed abnormal pattern in the asymptomatic eyes of patients with unilateral ICSC. Summary Spectral-domain optical coherence tomography showed morphologic alterations in retinal pigment epithelium in both eyes of patients with idiopathic central serous chorioretinopathy. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-009-9302-2Authors Pawan Gupta, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research Department of Ophthalmology Chandigarh 160012 IndiaVishali Gupta, Advanced Eye Centre, Post Graduate Institute of Medical Education and ...
Source: International Ophthalmology - January 30, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Clinical findings in unilateral acute idiopathic maculopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of unilateral acute idiopathic maculopathy (UAIM) with new clinical findings. A 34-year-old Japanese man had a neurosensory retinal detachment (~5 disk diameters) with yellowish-white exudates at the macula in the left eye (visual acuity (VA) 0.4). Fluorescein angiography (FA) showed early hypofluorescent spots and late pooling in the subretinal space. Three weeks after onset, indocyanine green angiography (IA) showed numerous hypofluorescent spots at the lesion. Optical coherence tomography (OCT) showed subretinal fluids and an elevated choroidal lesion with low reflectivity, suggesting choroidal edem...
Source: International Ophthalmology - January 29, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Long-term control of choroidal neovascularization in quiescent congenital toxoplasma retinochoroiditis with photodynamic therapy: 4-year resultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Photodynamic therapy seems to be a safe and effective approach to the long-term control of subfoveal CNV associated with toxoplasmic retinochoroiditis. Further trials are needed to validate these findings. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-008-9291-6Authors Piergiorgio Neri, Polytechnic University of Marche The Neuroscience Department–Ophthalmology Section Ancona ItalyLucia Mercanti, Polytechnic University of Marche The Neuroscience Department–Ophthalmology Section Ancona ItalyCesare Mariotti, Polytechnic University of Marche The Neuroscience Department–Ophthalmolo...
Source: International Ophthalmology - January 29, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Role of residual vitreous cortex removal in prevention of postoperative vitreous hemorrhage in diabetic vitrectomyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Residual vitreous cortex removal may be beneficial in reducing recurrence of postoperative vitreous hemorrhage following diabetic vitrectomy. Further randomized studies should be performed to evaluate the potential of this surgical technique in preventing postoperative recurrent vitreous hemorrhage following diabetic vitrectomy. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-009-9298-7Authors Rizwan A. Cheema, Dhahran Eye Specialist Hospital Vitreo-Retinal Service Dhahran KSAJaved Mushtaq, Dhahran Eye Specialist Hospital Vitreo-Retinal Service Dhahran KSAMaheera A. Cheema, Cardiff U...
Source: International Ophthalmology - January 25, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Case of lacrimal gland inflammation associated with ulcerative colitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of lacrimal gland pseudotumor as the presenting sign of ulcerative colitis. A 25-year-old woman presented with a right upper eyelid swelling and pain. Intravenous administration of prednisolone was initiated on suspicion of lacrimal gland inflammation (pseudotumor). Although the treatment markedly reduced her ocular symptoms, she developed lower abdominal cramping and diarrhea with the 5 mg/day of oral prednisolone. Sigmoid colonoscopy and colon biopsy led to make a diagnosis of ulcerative colitis. Ulcerative colitis improved significantly with increased dose of steroid and additive mesalazine the...
Source: International Ophthalmology - January 25, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Role of intravitreal bevacizumab in the management of Eales’ diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Intravitreal bevacizumab injections may be effective as an adjunctive or alternative treatment of retinal neovascularization in Eales’ disease, where inadequate visualization precludes laser photocoagulation. This approach may also be useful in avoiding vitreoretinal surgical intervention in certain cases. Intravitreal bevacizumab was well tolerated by our patients, and no adverse effects were observed. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-009-9292-0Authors Bhuvan Chanana, All India Institute of Medical Sciences Dr. Rajendra Prasad Centre for Ophthalmic Sciences 91, Poc...
Source: International Ophthalmology - January 23, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Macular sensitivity changes for detection of chloroquine toxicity in asymptomatic patientEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Chloroquine retinal toxicity can be recognized in a subclincal form by the presence of early changes in macular sensitivity, detected by MP-1. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10792-009-9297-8Authors Martina Angi, Royal Liverpool University Hospital St Paul’s Eye Unit Prescot Street Liverpool L7 8XP UKVito Romano, S. Sebstiano Hospital Department of Ophthalmology Caserta ItalyXavier Valldeperas, Royal Liverpool University Hospital St Paul’s Eye Unit Prescot Street Liverpool L7 8XP UKFerdinando Romano, S. Sebstiano Hospital Department of Ophthalmology Caserta ItalyMario R. R...
Source: International Ophthalmology - January 23, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Outcome of primary adult optical penetrating keratoplasty with imported donor corneasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In our patient population, excellent graft survival was achieved utilizing internationally acquired donor tissue for eyes with keratoconus, stromal dystrophy, and stromal scarring, but not for those with corneal edema. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-009-9295-xAuthors Michael D. Wagoner, King Khaled Eye Specialist Hospital Department of Ophthalmology Riyadh Kingdom of Saudi ArabiaEl-Sayed Gonnah, King Khaled Eye Specialist Hospital Department of Ophthalmology Riyadh Kingdom of Saudi ArabiaAbdul-Elah Al-Towerki, King Khaled Eye Specialist Hospital Department of Ophthal...
Source: International Ophthalmology - January 23, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Epidemic of unilateral panuveitis in children from Brazilian Amazonia: clinical and etiological aspects in seven patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Freshwater sponge spicules could be potential new etiological agents of ocular pathology, but further studies are needed, considering the heterogeneity of the ocular lesions and results of serological and environmental studies. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-009-9294-yAuthors Daniel Vítor Vasconcelos-Santos, Hospital São Geraldo/HC – Universidade Federal de Minas Gerais – UFMG Rua Espírito Santo, 1634/102 Belo Horizonte MG 30.160-031 BrazilFernando Oréfice, Hospital São Geraldo/HC – Universidade Federal de Minas Gerais – UFMG Rua Espírito Santo, 1634/102...
Source: International Ophthalmology - January 23, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Suboptimal therapy controls clinically apparent disease but not subclinical progression of Vogt-Koyanagi-Harada diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Submaximal doses of inflammation suppressive therapy are sufficient to suppress clinically apparent disease but not the underlying lesion process. This explains the propensity for sunset glow fundus in seemingly controlled disease. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-008-9288-1Authors Tatsushi Kawaguchi, Tokyo Medical and Dental University Graduate School of Medicine Department of Ophthalmology and Visual Science 1-5-45 Yushima, Bunkyo-ku Tokyo 113-8519 JapanShintaro Horie, Tokyo Medical and Dental University Graduate School of Medicine Department of Ophthalmology and Vis...
Source: International Ophthalmology - January 17, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Latanoprost-induced changes in the iris and trabeculum: an electron-microscopic morphological studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Latanoprost therapy causes pigment accumulation in the iris and trabeculum of patients in short-term therapy. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10792-008-9285-4Authors Nilgun Yildirim, Eskisehir Osmangazi University Faculty of Medicine Department of Ophthalmology Meselik, Eskisehir TurkeyAfsun Sahin, Eskisehir Osmangazi University Faculty of Medicine Department of Ophthalmology Meselik, Eskisehir TurkeySelcuk Kara, Eskisehir Osmangazi University Faculty of Medicine Department of Ophthalmology Meselik, Eskisehir TurkeyCengiz Baycu, Eskisehir Osmangazi University Faculty of Medicine...
Source: International Ophthalmology - January 13, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Comparison of 90-s versus 5-min intraoperative 5-fluorouracil in trabeculectomyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To compare the relative efficacy of trabeculectomy surgery with 90-s and 5-min intraoperative exposure time to 5-fluorouracil. This was a retrospective, non-randomized comparative study. 41 eyes of 33 consecutive patients in the study group were compared to 40 eyes of 30 consecutive patients in the historical control group. Both groups were exposed to 5-fluorouracil (50 mg/ml) during trabeculectomy surgery. The exposure time was 90 s for the study group and 5 min for the control group. Three criteria were used to define surgical success: IOP (intraocular pressure) less than 21 m...
Source: International Ophthalmology - January 10, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Excellent visual outcome following Aspergillus flavus endogenous endophthalmitis—farmer’s lung diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Early treatment of A. flavus endophthalmitis with pars plana vitrectomy, intravitreal and systemic amphotericin can lead to good visual outcomes. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10792-008-9289-0Authors Sophie J. Bakri, Mayo Clinic Department of Ophthalmology 200 First St SW Rochester 55905 MN USAJonathan E. Sears, Cleveland Clinic Foundation Cole Eye Institute Cleveland 44195 OH USAGary W. Procop, Cleveland Clinic Foundation Department of Clinical Microbiology Cleveland 44195 OH USARabin Shrestha, Cleveland Clinic Foundation Department of Infectious Disease Cleveland 44195 ...
Source: International Ophthalmology - January 9, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Manual small incision cataract surgery in a United Kingdom university teaching hospital settingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion MSICS is safe and effective for dense and brunescent cataracts in a UK university hospital setting. However, it was associated with a statistically significant increase in astigmatism postoperatively. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-008-9286-3Authors Ghee Soon Ang, Aberdeen Royal Infirmary Department of Ophthalmology, Eye Clinic Foresterhill, Aberdeen AB25 2ZN UKSamantha Wheelan, Aberdeen Royal Infirmary Department of Ophthalmology, Eye Clinic Foresterhill, Aberdeen AB25 2ZN UKFrank D. Green, Aberdeen Royal Infirmary Department of Ophthalmology, Eye Clinic Foresterhill...
Source: International Ophthalmology - January 8, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Case control study of dry eye and related ocular surface abnormalities in Ibadan, NigeriaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion A close relationship exists between ocular irritation symptoms, surface abnormalities and functional evidence of tear instability. Such patients should be treated empirically or screened for dry eyes. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-008-9281-8Authors C. O. Bekibele, University of Ibadan Department of Ophthalmology, University College Hospital and College of Medicine Ibadan NigeriaA. M. Baiyeroju, University of Ibadan Department of Ophthalmology, University College Hospital and College of Medicine Ibadan NigeriaA. Ajaiyeoba, University of Ibadan Department of Ophthalmol...
Source: International Ophthalmology - December 23, 2008 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Intravitreal bevacizumab treatment of macular edema in central retinal vein occlusion: one-year resultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Intravitreal bevacizumab resulted in a significant decrease in CRT without significant improvement of visual acuity in patients with non-ischemic CRVO after a follow-up of 12 months. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-008-9282-7Authors Julia Beutel, University Clinic of Schleswig-Holstein Eye Hospital Campus Lübeck, Ratzeburger Allee 160 23538 Lübeck GermanyFocke Ziemssen, Eberhard-Karls University of Tuebingen University Eye Hospital at the Centre for Ophthalmology Schleichstrasse 12–16 72076 Tuebingen GermanyMatthias Lüke, University Clinic of Schleswig-Holste...
Source: International Ophthalmology - December 21, 2008 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Worldwide geographical distribution of ophthalmology publicationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract International peer-reviewed publications form the basis of evidence-based medicine and are one of the main indicators of ophthalmology research activity. This paper examines the origins of such articles in relation to geographical location, population demographics and economic research profiles. Publications from five ophthalmology journals over 5 years were analysed using the Medline/Pubmed search engine. Country of origin was ascertained based on the address of the corresponding author. Worldwide ophthalmology research output was analysed in relation to population demographics and research ex...
Source: International Ophthalmology - November 21, 2008 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Comparison of the quality score of intraocular pressure and ocular pulse amplitude values measured by the Pascal dynamic contour tonometerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The Pascal dynamic contour tonometer (PDCT) is designed to measure intraocular pressure (IOP) largely independent of the corneal properties. It is equipped with a digital LCD screen that displays the IOP, the ocular pulse amplitude (OPA) and the quality score (Q) of the measurements [range 1 (excellent) to 5 (poor)]. The manufacturer has recommended discarding the IOP and OPA values of Q4 and Q5. The aim of our study was to assess if IOP and OPA measurements with Q3 are acceptable for clinical and research purposes. This is a prospective, observational study in which both patients with ocular hypert...
Source: International Ophthalmology - November 20, 2008 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Retained lens fragment in the anterior segment as a cause of recurrent anterioruveitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A 61-year-old male developed recurrent anterior uveitis over a period of 8 months after an uncomplicated phacoemulsification and posterior chamber intraocular lens implantation surgery. This was subsequently found to be due to a retained lens fragment in the anterior segment, with complete resolution following surgical extraction of the fragment. To our knowledge, this is the first report of recurrent anterior uveitis attributable to a retained lens fragment following uncomplicated cataract surgery, and the diagnosis should be considered in a pseudophakic patient presenting with recurrent episo...
Source: International Ophthalmology - November 20, 2008 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

A rare brain developmental anomaly in a patient with Usher’s syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a rare brain developmental anomaly in Usher’s syndrome. We present a 43-year-old male with visual disturbance, hearing loss, and headache. Retinitis pigmentosa and sensorineural hearing loss were determined and he was diagnosed with Usher’s syndrome according to the clinical findings. Magnetic resonance imaging showed an arachnoid cyst on the left temporal lobe, cavum septum pellucidum et vergae. Uneventful cataract surgery was performed in both eyes. He was suggested to be followed up periodically for the arachnoid cyst and to use a hearing device. Although auditory and visual disturbances are the typica...
Source: International Ophthalmology - November 13, 2008 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Spectrum of Behçet’s disease in the Indian populationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The purpose of this investigation is to study the clinical profile of Behçet’s disease in the Indian population as seen in a tertiary referral uveitis clinic. A retrospective non-comparative case series was used. The records of all of the patients seen in our uveitis clinic between January 1990 and December 2006 were screened and patients with a diagnosis of Behçet’s disease were enrolled. The diagnosis was based on the Japanese diagnostic criteria and patients were classified into complete, incomplete, suspected, and possible Behçet’s disease. Information on the patient’s demographic cha...
Source: International Ophthalmology - October 21, 2008 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Visante® anterior segment OCT in a patient with gas bubbles in the anterior chamber after femtosecond laser corneal flap formationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A patient with anterior chamber gas bubbles after LASIK flap formation with femtosecond laser is presented. A 33-year-old male patient had LASIK for myopia with corneal flap formation with IntraLase® FS30 femtosecond laser. In the right eye, air bubbles were observed in anterior chamber after successful flap formation. Laser correction was completed successfully, by Wavelight® Allegretto WaveTM Eye-Q excimer laser, without eye-tracker. Visante® anterior segment optical coherence tomography imaging displayed that the pocket extended to limbal area, with stromal bed thickness of >600 μm at ...
Source: International Ophthalmology - October 16, 2008 Category: Opthalmology Tags: International Ophthalmology Source Type: journals