ABPI reporting and compression recommendations in global clinical practice guidelines on venous leg ulcer management: A scoping review
Clinical practice guidelines (CPGs) for venous leg ulcer (VLU) management recommend below ‐knee compression to improve healing outcomes after calculating the ankle‐brachial pressure index (ABPI) to rule out significant arterial disease. This systematic scoping review aimed to complete a qualitative and quantitative content analysis of international CPGs for VLU management to determin e if consensus existed in relation to recommendations for compression application based on an ABPI reading and clinical assessment. Our review shows that there is a lack of consensus across 13 VLU CPGs and a lack of clear guidance in relat...
Source: International Wound Journal - November 28, 2018 Category: Surgery Authors: Carolina D. Weller, Victoria Team, John D. Ivory, Kimberley Crawford, Georgina Gethin Tags: ORIGINAL ARTICLE Source Type: research

Comparison of the efficacy and safety of povidone ‐iodine foam dressing (Betafoam), hydrocellular foam dressing (Allevyn), and petrolatum gauze for split‐thickness skin graft donor site dressing
We evaluated the efficacy and safety of a povidone ‐iodine (PVP‐I) foam dressing (Betafoam) for donor site dressing versus a hydrocellular foam dressing (Allevyn) and petrolatum gauze. This prospective Phase 4 study was conducted between March 2016 and April 2017 at eight sites in Korea. A total of 106 consenting patients (aged ≥ 19 year s, scheduled for split‐thickness skin graft) were randomised 1:1:1 to PVP‐I foam, hydrocellular, or petrolatum gauze dressings for up to 28 days after donor site collection. We assessed time to complete epithelialisation, proportion with complete epithelialisation at Day ...
Source: International Wound Journal - November 26, 2018 Category: Surgery Authors: Chang Sik Pak, Dae Hwan Park, Tae Suk Oh, Won Jai Lee, Young Joon Jun, Kyung Ah Lee, Kap Sung Oh, Kyung Hee Kwak, Jong Won Rhie Tags: ORIGINAL ARTICLE Source Type: research

Carboxytherapy: Controls the inflammation and enhances the production of fibronectin on wound healing under venous insufficiency
To examine the influence of carboxytherapy on wound healing under venous insufficiency, full ‐thickness excisional wounds were created onWistar rats. We used three groups with 32 rats each: Group (I): daily cleaning with 0.9% saline solution; Group Sulfadiazine (II): 1% silver sulfadiazine; and Carboxytherapy (III): subcutaneous application of 0.3 mL of carbon dioxide. The predetermined periods of analysis were the 3rd, 7th, 14th, and 30th day. The slides were stained with haematoxylin and eosin and Picrosirius red and submitted for immunohistochemistry. Groups II and III presented a statistically significant decrease in...
Source: International Wound Journal - November 22, 2018 Category: Surgery Authors: Themis M. M. Brochado, Laynna de Carvalho Schweich, Naudimar Di Pietro Sim ões, Rodrigo J. Oliveira, Andréia C. M. B. Antoniolli‐Silva Tags: ORIGINAL ARTICLE Source Type: research

The use of fat grafting and platelet ‐rich plasma for wound healing: A review of the current evidence
Fat grafting is becoming a common procedure in regenerative medicine because of its high content of growth factors and adipose derived stem cells (ADSCs) and the ease of harvest, safety, and low cost. The high concentration of ADSCs found in fat has the potential to differentiate into a wide range of wound ‐healing cells including fibroblasts and keratinocytes as well as demonstrating proangiogenic qualities. This suggests that fat could play an important role in wound healing. However retention rates of fat grafts are highly variable due in part to inconsistent vascularisation of the transplanted f at. Furthermore, cond...
Source: International Wound Journal - November 20, 2018 Category: Surgery Authors: Oliver J. Smith, Gavin Jell, Ash Mosahebi Tags: ORIGINAL ARTICLE Source Type: research

Wound ‐healing effect of adipose stem cell‐derived extracellular matrix sheet on full‐thickness skin defect rat model: Histological and immunohistochemical study
The potential use of extracellular matrix (ECM) as a source of wound dressing material has recently received much attention. The ECM is an intricate network of various combinations of elastin, collagens, laminin, fibronectin, and proteoglycans that play a key role in stimulating cell proliferation and differentiation. We evaluated the efficacy of an ECM sheet derived from human adipose tissue as a wound dressing material to enhance healing. We prepared a novel porous ECM sheet dressing scaffold from human adipose tissue. in vitro analysis of the ECM sheets showed efficient decellularisation; absence of immunostimulatory co...
Source: International Wound Journal - November 20, 2018 Category: Surgery Authors: Yoon J. Lee, Seung E. Baek, Sujin Lee, Yong W. Cho, Yeon J. Jeong, Ki J. Kim, Young J. Jun, Jong W. Rhie Tags: ORIGINAL ARTICLE Source Type: research

Using a muscle pump activator device to stimulate healing for non ‐healing lower leg wounds in long‐term care residents
The objective of this LTC Innovation pilot was to test the value of a promising new neuromuscular stimulation device in elevating the experience and satisfa ction of the residents, engaging and empowering the nursing staff, and improving healing and/or reducing costs. Small, wireless, and worn at the knee, this muscle pump activator is self‐contained, wearable, and battery‐powered to increase lower‐leg blood circulation (up to 60% of that achieved by walking). It has no wires, weighs just 10 g, and is easy to use. Nurses in four LTC homes identified residents with non‐healing lower leg wounds. Consent was obtained,...
Source: International Wound Journal - November 20, 2018 Category: Surgery Authors: Connie Harris, Dorace Ramage, Azi Boloorchi, Lisa Vaughan, Gabriella Kuilder Tags: ORIGINAL ARTICLE Source Type: research

Management of sacrococcygeal pilonidal sinus disease
The ideal treatment for patients who suffer from pilonidal sinus disease should lead to a cure with a rapid recovery period allowing a return to normal daily activities, with a low level of associated morbidity. A variety of different surgical techniques have been described for the primary treatment of pilonidal sinus disease and current practice remains variable and contentious. Whilst some management options have improved outcomes for some patients, the complications of surgery, particularly related to wound healing, often remain worse than the primary disease. This clinical review aims to provide an update on the manage...
Source: International Wound Journal - November 15, 2018 Category: Surgery Authors: Rhiannon L. Harries, Abdullah Al ‐Qallaf, Jared Torkington, Keith G. Harding Tags: ORIGINAL ARTICLE Source Type: research

Nutritional management of older hospitalised patients with pressure injuries
This cross ‐sectional, multicentre study was conducted in hospitals to investigate nutritional interventions conducted in patients aged 70 years or older with (risk of) pressure injuries. A total of 1412 patients from 33 hospitals with 208 wards participated in the study. A standardised questionnaire was use d to collect demographic data and data on care dependency, malnutrition risk, risk for/prevalence of pressure injuries, and nutritional interventions. Data analyses were conducted by using descriptive statistics, chi‐square tests, or independent t‐tests. According to the Braden Scale, 678 (48.0% ) of the patients...
Source: International Wound Journal - November 15, 2018 Category: Surgery Authors: Doris Eglseer, Manuela H ödl, Christa Lohrmann Tags: ORIGINAL ARTICLE Source Type: research

Use of platelet ‐rich plasma to facilitate wound healing
Platelet ‐rich plasma (PRP) is widely used nowadays in different fields of medicine, affecting physiological processes including tissue regeneration. The use of PRP in maxillofacial surgical interventions and its efficiency in the improvement of postoperative wound healing were analysed. Patients undergoin g plastic and reconstructive surgeries in the maxillofacial region were recruited: 50 patients were enrolled into a control group (received no PPRP injection) and 50 patients were enrolled into a treatment group, where PRP was applied during the surgical procedure. Evaluation of treatment outcomes w as carried out by d...
Source: International Wound Journal - November 15, 2018 Category: Surgery Authors: Yuliya Menchisheva, Ulmeken Mirzakulova, Rudolf Yui Tags: ORIGINAL ARTICLE Source Type: research

The clinical dynamic changes of macrophage phenotype and function in different stages of human wound healing and hypertrophic scar formation
The pathogenesis of hypertrophic scar (HS) is still poorly understood. Macrophages, especially the polarisation of that to M1 or M2, play a pivotal role in control of the degree of scar formation. Profiling of macrophage phenotypes in human specimens during long ‐term period of wound healing and HS formation may provide valuable clinical evidence for understanding the pathology of human scars. Human wound and HS specimens were collected, the macrophage phenotype was identified by immunofluorescence, and biomarkers and cytokines associated with M1 and M2 m acrophages were detected by RT‐PCR. The correlation between the ...
Source: International Wound Journal - November 15, 2018 Category: Surgery Authors: Lin Chen, Jianzhang Wang, Shengxu Li, Zhou Yu, Bei Liu, Baoqiang Song, Yingjun Su Tags: ORIGINAL ARTICLE Source Type: research

Comparative study on the donor site aesthetic outcome between epidermal graft and split ‐thickness skin graft
This study is the first to objectively measure the clinical appearance of the EG donor site against SSG. EG donor site has faster healing with excellent scarring and good colour match with its surrounding normal skin at all time points compared with SSG. (Source: International Wound Journal)
Source: International Wound Journal - November 15, 2018 Category: Surgery Authors: Muholan Kanapathy, Afshin Mosahebi Tags: ORIGINAL ARTICLE Source Type: research

“Pikachu‐shaped” flap for extramammary Paget's disease
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - November 15, 2018 Category: Surgery Authors: Chan Woo Kim, Tae Hwan Park Tags: LETTER TO THE EDITOR Source Type: research

Health benefits of an innovative model of care for chronic wounds patients in Queensland
Wound management in Australia suffers from a lack of adequate coordination and communication between sectors that impacts patient outcomes and costs. Wound Innovations is a specialist service comprising of a transdisciplinary team that aims to streamline and improve patient care and outcomes. We compared patient experiences and outcomes prior to accessing this specialist service, and the 3 months following their enrolment at the clinic. Information on patient experiences, wound history, and outcomes was collected through interviews and a review of medical records for the 12  months prior to enrolment at the clinic. Wound...
Source: International Wound Journal - November 11, 2018 Category: Surgery Authors: Ruth Tulleners, David Brain, Xing Lee, Qinglu Cheng, Nicholas Graves, Rosana E. Pacella Tags: ORIGINAL ARTICLE Source Type: research

Calendar
International Wound Journal, Volume 15, Issue 6, Page 1053-1053, December 2018. (Source: International Wound Journal)
Source: International Wound Journal - November 9, 2018 Category: Surgery Tags: CALENDAR OF EVENTS Source Type: research

Issue Information
International Wound Journal, Volume 15, Issue 6, Page 857-860, December 2018. (Source: International Wound Journal)
Source: International Wound Journal - November 9, 2018 Category: Surgery Tags: ISSUE INFORMATION Source Type: research