Immunochemistry-based quantification of tumor-infiltrating lymphocytes and immunoscore as prognostic biomarkers in bladder cancer
CONCLUSION: TILs and immunoscore might be effective prognostic tools in BC. However, standardized quantification methods and further investigation on larger samples are highly recommended to definitively attest the prognostic value of TILs and IS in BC.PMID:38523233 | DOI:10.1186/s43046-024-00212-8 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - March 25, 2024 Category: Cancer & Oncology Authors: Sarra Ben Rejeb Sirine Elfekih Nadia Kouki Rami Boulma Hassen Khouni Source Type: research

Immunochemistry-based quantification of tumor-infiltrating lymphocytes and immunoscore as prognostic biomarkers in bladder cancer
CONCLUSION: TILs and immunoscore might be effective prognostic tools in BC. However, standardized quantification methods and further investigation on larger samples are highly recommended to definitively attest the prognostic value of TILs and IS in BC.PMID:38523233 | DOI:10.1186/s43046-024-00212-8 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - March 25, 2024 Category: Cancer & Oncology Authors: Sarra Ben Rejeb Sirine Elfekih Nadia Kouki Rami Boulma Hassen Khouni Source Type: research

CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CONCLUSIONS: This novel signaling could regulate the biological behaviours of bladder cancer cells, and these findings highlighted circMCTP2 as a critical target for treating bladder cancer.PMID:38494582 | DOI:10.1186/s43046-024-00206-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - March 18, 2024 Category: Cancer & Oncology Authors: Yan Liu Kexin Zhang Xianxu Yang Source Type: research

CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CONCLUSIONS: This novel signaling could regulate the biological behaviours of bladder cancer cells, and these findings highlighted circMCTP2 as a critical target for treating bladder cancer.PMID:38494582 | DOI:10.1186/s43046-024-00206-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - March 18, 2024 Category: Cancer & Oncology Authors: Yan Liu Kexin Zhang Xianxu Yang Source Type: research

CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CONCLUSIONS: This novel signaling could regulate the biological behaviours of bladder cancer cells, and these findings highlighted circMCTP2 as a critical target for treating bladder cancer.PMID:38494582 | DOI:10.1186/s43046-024-00206-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - March 18, 2024 Category: Cancer & Oncology Authors: Yan Liu Kexin Zhang Xianxu Yang Source Type: research

CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CONCLUSIONS: This novel signaling could regulate the biological behaviours of bladder cancer cells, and these findings highlighted circMCTP2 as a critical target for treating bladder cancer.PMID:38494582 | DOI:10.1186/s43046-024-00206-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - March 18, 2024 Category: Cancer & Oncology Authors: Yan Liu Kexin Zhang Xianxu Yang Source Type: research

CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CONCLUSIONS: This novel signaling could regulate the biological behaviours of bladder cancer cells, and these findings highlighted circMCTP2 as a critical target for treating bladder cancer.PMID:38494582 | DOI:10.1186/s43046-024-00206-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - March 18, 2024 Category: Cancer & Oncology Authors: Yan Liu Kexin Zhang Xianxu Yang Source Type: research

CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
CONCLUSIONS: This novel signaling could regulate the biological behaviours of bladder cancer cells, and these findings highlighted circMCTP2 as a critical target for treating bladder cancer.PMID:38494582 | DOI:10.1186/s43046-024-00206-6 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - March 18, 2024 Category: Cancer & Oncology Authors: Yan Liu Kexin Zhang Xianxu Yang Source Type: research

Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
J Egypt Natl Canc Inst. 2024 Mar 11;36(1):7. doi: 10.1186/s43046-024-00211-9.ABSTRACTThe progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their isolated microenvironments. Over the past few decades, researchers have investigated the metastatic spread of cancer extensively, identifying multiple stages in the process, such as intravasation, extravasation, tumor latency, and the development of micrometastasis and macrometastasis. The premetastatic niche is established in target organs by the accumulation of aberrant immune cells and extracellular matrix proteins. Th...
Source: J Egypt Natl Canc In... - March 11, 2024 Category: Cancer & Oncology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research

Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
J Egypt Natl Canc Inst. 2024 Mar 11;36(1):7. doi: 10.1186/s43046-024-00211-9.ABSTRACTThe progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their isolated microenvironments. Over the past few decades, researchers have investigated the metastatic spread of cancer extensively, identifying multiple stages in the process, such as intravasation, extravasation, tumor latency, and the development of micrometastasis and macrometastasis. The premetastatic niche is established in target organs by the accumulation of aberrant immune cells and extracellular matrix proteins. Th...
Source: J Egypt Natl Canc In... - March 11, 2024 Category: Cancer & Oncology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research

Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
J Egypt Natl Canc Inst. 2024 Mar 11;36(1):7. doi: 10.1186/s43046-024-00211-9.ABSTRACTThe progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their isolated microenvironments. Over the past few decades, researchers have investigated the metastatic spread of cancer extensively, identifying multiple stages in the process, such as intravasation, extravasation, tumor latency, and the development of micrometastasis and macrometastasis. The premetastatic niche is established in target organs by the accumulation of aberrant immune cells and extracellular matrix proteins. Th...
Source: J Egypt Natl Canc In... - March 11, 2024 Category: Cancer & Oncology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research

Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
J Egypt Natl Canc Inst. 2024 Mar 11;36(1):7. doi: 10.1186/s43046-024-00211-9.ABSTRACTThe progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their isolated microenvironments. Over the past few decades, researchers have investigated the metastatic spread of cancer extensively, identifying multiple stages in the process, such as intravasation, extravasation, tumor latency, and the development of micrometastasis and macrometastasis. The premetastatic niche is established in target organs by the accumulation of aberrant immune cells and extracellular matrix proteins. Th...
Source: J Egypt Natl Canc In... - March 11, 2024 Category: Cancer & Oncology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research

Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
J Egypt Natl Canc Inst. 2024 Mar 11;36(1):7. doi: 10.1186/s43046-024-00211-9.ABSTRACTThe progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their isolated microenvironments. Over the past few decades, researchers have investigated the metastatic spread of cancer extensively, identifying multiple stages in the process, such as intravasation, extravasation, tumor latency, and the development of micrometastasis and macrometastasis. The premetastatic niche is established in target organs by the accumulation of aberrant immune cells and extracellular matrix proteins. Th...
Source: J Egypt Natl Canc In... - March 11, 2024 Category: Cancer & Oncology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research

Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
J Egypt Natl Canc Inst. 2024 Mar 11;36(1):7. doi: 10.1186/s43046-024-00211-9.ABSTRACTThe progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their isolated microenvironments. Over the past few decades, researchers have investigated the metastatic spread of cancer extensively, identifying multiple stages in the process, such as intravasation, extravasation, tumor latency, and the development of micrometastasis and macrometastasis. The premetastatic niche is established in target organs by the accumulation of aberrant immune cells and extracellular matrix proteins. Th...
Source: J Egypt Natl Canc In... - March 11, 2024 Category: Cancer & Oncology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research

Developing an efficient method for melanoma detection using CNN techniques
CONCLUSION: As per the comparisons between the two techniques customized CNN gives higher accuracy for the detection of melanoma.PMID:38407684 | DOI:10.1186/s43046-024-00210-w (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - February 26, 2024 Category: Cancer & Oncology Authors: Devika Moturi Ravi Kishan Surapaneni Venkata Sai Geethika Avanigadda Source Type: research