Characterization of Ceftriaxone-Resistant < em > Haemophilus influenzae < /em > Among Korean Children
CONCLUSION: The emergence of ceftriaxone-resistant H. influenzae with ceftriaxone MIC values of up to 0.75 mg/L was observed even in children in South Korea, with most associated with S385T and L389F substitutions. The N526K mutation alone does not significantly impact ceftriaxone resistance. Further large-scale studies are essential to investigate changes in antibiotic resistance patterns and factors influencing antibiotic resistance in H. influenzae isolated from pediatric patients in Korea.PMID:38651222 | DOI:10.3346/jkms.2024.39.e136 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 23, 2024 Category: General Medicine Authors: Sanghoon Lee Gahee Kim Jung Hwa Kim Mi-Na Kim Jina Lee Source Type: research

In This Issue on 22-April-2024
J Korean Med Sci. 2024 Apr 22;39(15):e138. doi: 10.3346/jkms.2024.39.e138.NO ABSTRACTPMID:38651223 | DOI:10.3346/jkms.2024.39.e138 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 23, 2024 Category: General Medicine Authors: Jin-Hong Yoo Source Type: research

Current Status and Associated Factors of Post-Hemorrhagic Hydrocephalus in Infants of 22 to 28 Weeks Gestation With Severe Intraventricular Hemorrhage in Korea: A Nationwide Cohort Study
CONCLUSION: It is necessary to maintain meticulous monitoring and neurological intervention for infants with PHH not only during admission but also after discharge. In addition, identifying the clinical factors that increase the likelihood of developing PHH from severe IVH is crucial.PMID:38651224 | DOI:10.3346/jkms.2024.39.e139 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 23, 2024 Category: General Medicine Authors: Misun Yang Sumin Kim Se In Sung Yun Sil Chang Won Soon Park So Yoon Ahn Source Type: research

Outcomes of Concomitant Maze Procedure in Tricuspid Repair for Severe Tricuspid Regurgitation
CONCLUSION: The Maze procedure during TV repair in patients with severe TR and persistent AF showed acceptable SR rates and lower MACCE rates compared to those without the procedure, while also promoting LA reverse remodeling.PMID:38651225 | DOI:10.3346/jkms.2024.39.e143 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 23, 2024 Category: General Medicine Authors: Ilkun Park Suryeun Chung Yang Hyun Cho Kiick Sung Wook Sung Kim Kyungsub Song Joong Hyun Ahn Chang Seok Jeon Pyo Won Park Dong Seop Jeong Source Type: research

Interim Estimates of 2023-2024 Seasonal Influenza Vaccine Effectiveness Among Adults in Korea
In this study, we aimed to estimate the interim vaccine effectiveness (VE) of the influenza vaccination to prevent influenza during the early season. From November 1, 2023, to December 31, 2023, we enrolled 2,632 subjects with influenza-like illness from eight hospitals participating in hospital-based influenza morbidity and mortality surveillance. A retrospective test-negative case-control study was conducted to estimate the VE. The results showed an adjusted VE of 22.5% (95% confidence interval [CI], 6.6 to 35.8) for the total population. The adjusted VE was 22.3% (95% CI, 6.1 to 35.7) for influenza A and 9.4% (95% CI, -...
Source: J Korean Med Sci - April 23, 2024 Category: General Medicine Authors: Yu Jung Choi Jang Wook Sohn Won Suk Choi Seong-Heon Wie Jacob Lee Jin-Soo Lee Hye Won Jeong Joong Sik Eom Eliel Nham Hye Seong Jin Gu Yoon Ji Yun Noh Joon Young Song Hee Jin Cheong Woo Joo Kim Source Type: research

Comprehensive Guidance for the Prevention of Periprosthetic Joint Infection After Total Joint Arthroplasty and Pitfalls in the Prevention
J Korean Med Sci. 2024 Apr 22;39(15):e147. doi: 10.3346/jkms.2024.39.e147.ABSTRACTTotal joint arthroplasty (TJA) is a surgical procedure, in which parts of damaged joints are removed and replaced with a prosthesis. The main indication of TJA is osteoarthritis, and the volume of TJA is rising annually along with the increase of aged population. Hip and knee are the most common joints, in which TJAs are performed. The TJA prosthesis is composed of metal, plastic, or ceramic device. Even though TJA is the most successful treatment for end-stage osteoarthritis, it is associated with various complications, and periprosthetic jo...
Source: J Korean Med Sci - April 23, 2024 Category: General Medicine Authors: Javad Parvizi Yonghan Cha Emanuele Chisari Kangbaek Kim Kyung-Hoi Koo Source Type: research

Letter to the Editor: A Discussion About Pharmacovigilance Study Methods
J Korean Med Sci. 2024 Apr 22;39(15):e142. doi: 10.3346/jkms.2024.39.e142.NO ABSTRACTPMID:38651228 | DOI:10.3346/jkms.2024.39.e142 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 23, 2024 Category: General Medicine Authors: Joowon Lee Source Type: research

Evaluating Linkage Quality of Population-Based Administrative Data for Health Service Research
CONCLUSION: This study confirms the possibility of building health and medical data at the national level as the first data linkage quality verification study using big data from the HIRA. Analyzing the quality of linkages is crucial for comprehending linkage errors and generating reliable analytical outcomes. Linkers should increase the reliability of linked data by providing linkage error-related information to researchers. The results of this study will serve as reference data to increase the reliability of multicenter data linkage studies.PMID:38622936 | PMC:PMC11018984 | DOI:10.3346/jkms.2024.39.e127 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Ji-Woo Kim Hyojung Choi Hyun Jeung Lim Miae Oh Jae Joon Ahn Source Type: research

Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea
CONCLUSION: The omicron group did not demonstrate better clinical outcomes than the pre-omicron group, and exhibited significant disease severity compared to the influenza group. Considering the likely persistence of COVID-19 infections, it is imperative to sustain comprehensive studies and ongoing policy support for the virus to enhance the prognosis for individuals affected by COVID-19.PMID:38622937 | PMC:PMC11018986 | DOI:10.3346/jkms.2024.39.e128 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Jae Kyeom Sim Hye Sun Lee Juyeon Yang Jin Gwack Bryan Inho Kim Jeong-Ok Cha Kyung Hoon Min Young Seok Lee Severe Acute Respiratory Infection (SARI) Investigators Source Type: research

Antimicrobial Use and Carbapenem-Resistant Enterobacterales in Korea: A Nationwide Case-Control Study With Propensity Score Matching
CONCLUSION: The utilization of broad-spectrum antibiotics and the presence of comorbidities are associated with increasing development of CRE. This study emphasizes the importance of antimicrobial stewardship in reducing broad-spectrum antibiotic use and CRE disease burden in Korea.PMID:38622938 | PMC:PMC11018987 | DOI:10.3346/jkms.2024.39.e132 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Ki Tae Kwon Yoonjung Kim Shin-Woo Kim Hyun-Ha Chang Soyoon Hwang Sohyun Bae Eunkyung Nam Source Type: research

Review of COVID-19 Therapeutics by Mechanism: From Discovery to Approval
J Korean Med Sci. 2024 Apr 15;39(14):e134. doi: 10.3346/jkms.2024.39.e134.ABSTRACTThe global research and pharmaceutical community rapidly mobilized to develop treatments for coronavirus disease 2019 (COVID-19). Existing treatments have been repurposed and new drugs have emerged. Here we summarize mechanisms and clinical trials of COVID-19 therapeutics approved or in development. Two reviewers, working independently, reviewed published data for approved COVID-19 vaccines and drugs, as well as developmental pipelines, using databases from the following organizations: United States Food and Drug Administration (US-FDA), Euro...
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Hee Sun Choi A Young Choi Jeffrey B Kopp Cheryl A Winkler Sung Kweon Cho Source Type: research

In This Issue on 15-April-2024
J Korean Med Sci. 2024 Apr 15;39(14):e135. doi: 10.3346/jkms.2024.39.e135.NO ABSTRACTPMID:38622940 | PMC:PMC11018983 | DOI:10.3346/jkms.2024.39.e135 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Jin-Hong Yoo Source Type: research

Comparison of the Clinical Outcomes Between Early and Delayed Transplantation After SARS-CoV-2 Infection
J Korean Med Sci. 2024 Apr 15;39(14):e137. doi: 10.3346/jkms.2024.39.e137.ABSTRACTOur study analyzed 95 solid organ transplant (SOT) and 78 hematopoietic stem cell transplant (HSCT) recipients with prior coronavirus disease 2019 (COVID-19). Patients who underwent transplantation within 30 days of COVID-19 infection comprised the early group, and those who underwent transplantation post-30 days of COVID-19 infection comprised the delayed group. In the early transplantation group, no patient, whether undergoing SOT and HSCT, experienced COVID-19-associated complications. In the delayed transplantation group, one patient each...
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Sang Hyun Ra A Reum Kim Hyeon Mu Jang Euijin Chang Seongman Bae Jiwon Jung Min Jae Kim Yong Pil Chong Sang-Oh Lee Sang-Ho Choi Yang Soo Kim Sung-Han Kim Source Type: research

Evaluating Linkage Quality of Population-Based Administrative Data for Health Service Research
CONCLUSION: This study confirms the possibility of building health and medical data at the national level as the first data linkage quality verification study using big data from the HIRA. Analyzing the quality of linkages is crucial for comprehending linkage errors and generating reliable analytical outcomes. Linkers should increase the reliability of linked data by providing linkage error-related information to researchers. The results of this study will serve as reference data to increase the reliability of multicenter data linkage studies.PMID:38622936 | DOI:10.3346/jkms.2024.39.e127 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Ji-Woo Kim Hyojung Choi Hyun Jeung Lim Miae Oh Jae Joon Ahn Source Type: research

Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea
CONCLUSION: The omicron group did not demonstrate better clinical outcomes than the pre-omicron group, and exhibited significant disease severity compared to the influenza group. Considering the likely persistence of COVID-19 infections, it is imperative to sustain comprehensive studies and ongoing policy support for the virus to enhance the prognosis for individuals affected by COVID-19.PMID:38622937 | DOI:10.3346/jkms.2024.39.e128 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Jae Kyeom Sim Hye Sun Lee Juyeon Yang Jin Gwack Bryan Inho Kim Jeong-Ok Cha Kyung Hoon Min Young Seok Lee Severe Acute Respiratory Infection (SARI) Investigators Source Type: research