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AI Hallucination
This essay reports on fictitious source materials created by AI chatbots, encourages human oversight to identify fabricated information, and suggests a creative use for these tools. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

My Favorite Sinus
This essay reflects on the author ’s approach to interviewing applicants for medical residency in the otolaryngology department. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Reconstruction for Salvage Laryngectomy With Limited Pharyngectomy
This cohort study examines whether the closure technique of salvage laryngectomy is associated with early postoperative and long-term functional outcomes. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Skip Polysomnography Before Adenotonsillectomy for Snoring? —Reply
In Reply We thank Kaditis et al for bringing attention to the insights and clinical complexities illuminated by the results of the Pediatric Adenotonsillectomy Trial for Snoring (PATS), as published in JAMA and JAMA Otolaryngology –Head& Neck Surgery. As elucidated by the authors, PATS introduced the term mild sleep-disordered breathing (SDB) to encompass children with both primary snoring (AHI,<1) and mild obstructive sleep apnea (OSA) (apnea-hypopnea index [AHI], 1-3), distinct from the conventional definition of mild OSA typically denoted by an AHI of 1 to 5. It is noteworthy that all participants in PATS under...
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Skip Polysomnography Before Adenotonsillectomy for Snoring?
To the Editor In December 2023, results of the Pediatric Adenotonsillectomy Trial for Snoring (PATS) were published in JAMA and JAMA Otolaryngology –Head& Neck Surgery. Like other elegantly designed and executed clinical trials, PATS triggers more questions than the answers provided. The novel term mild sleep-disordered breathing (SDB) is introduced that combines snoring with an apnea-hypopnea index (AHI) of less than 1 event/h (primary snoring) and AHI 1 to less than 3 events/h (mild obstructive sleep apnea [OSA]). Although both subgroups are indistinguishable regarding symptoms and morbidity, this term could confus...
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Considerations in Salvage Laryngectomy Reconstruction
Pharyngocutaneous fistula (PCF) is a dreaded complication from total laryngectomy (TL), as it can cause wound issues, lengthen hospitalization, increase costs, and prolong nothing-by-mouth status. In this issue of JAMA Otolaryngology –Head& Neck Surgery, Moreno et al evaluated 309 patients from multiple institutions who underwent salvage TL. This work nicely focuses on the subset of TL with limited pharyngeal defect amenable to primary closure (PC), distinguishing it from other work on this topic. The authors report a PCF rate of 29%. In their study, the investigators evaluated the use of free tissue transfer (FTT) v...
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Addressing Financial Toxicity in Head and Neck Cancer
This Viewpoint calls for consideration of the financial costs of head and neck cancer care when choosing treatment strategies for patients who may face severe financial stress or insolvency due to cancer treatment. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

TORS and Radiation Volume in Unknown Primary Squamous Cell Carcinoma of the Neck
This phase 2 trial assesses whether transoral robotic surgery and tailored radiotherapy are associated with favorable outcomes among patients with unknown primary squamous cell carcinoma. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharynx Cancer and Quality of Life —Reply
In Reply In reaction to our recent report on quality-of-life outcomes following neoadjuvant chemotherapy and transoral robotic surgery (NECTORS) for human papillomavirus virus –associated oropharyngeal squamous cell carcinoma (HPV-OPSCC), Granell and Gutierrez-Fonseca have raised concerns to which we would like to respond. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

Complete Clinical Response With Pembrolizumab for Cutaneous Squamous Cell Carcinoma
This case report describes an 89-year-old patient with prior cutaneous squamous cell carcinoma who presented with a new isolated metastasis and was subsequently treated with pembrolizumab, which produced a complete clinical response. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharynx Cancer and Quality of Life
To the Editor To deintensify treatment (avoid overtreatment) for patients with human papillomavirus virus –associated oropharyngeal squamous cell carcinoma (HPV-OPSCC) is certainly one of the hot topics in head and neck cancer, driven by the goal of enhancing quality of life. Although various strategies are under exploration, the unconventional inclusion of neoadjuvant chemotherapy by Silver et al has captured our attention. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

Interfacility Transfer Guidelines for Isolated Facial Trauma
This Viewpoint discusses the need to implement proposed guidelines for facial trauma assessment to prevent unnecessary interfacility transfer of patients with facial trauma despite most such patients having injuries that do not require surgical intervention. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 4, 2024 Category: ENT & OMF Source Type: research

Preoperative Circulating Tumor HPV DNA and Oropharyngeal Squamous Cell Disease
This cross-sectional study evaluates the association of preoperative circulating tumor HPV DNA levels with disease burden or adverse pathologic features among patients with HPV-associated oropharyngeal squamous cell carcinoma who have undergone primary transoral robotic surgery. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 4, 2024 Category: ENT & OMF Source Type: research

Trends in Oral Tongue Cancer Incidence in the US
This cross-sectional study examines US trends in oral tongue cancer incidence and the factors associated with future case burden. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 4, 2024 Category: ENT & OMF Source Type: research

Quality of Life and Depression Symptoms After Therapy De-Escalation in HPV+ Oropharyngeal SCC
This nonrandomized clinical trial quantifies quality of life and depression burden variables in patients undergoing de-escalation of human papillomavirus –mediated oropharyngeal squamous cell carcinoma therapy. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 4, 2024 Category: ENT & OMF Source Type: research