Unraveling the Role of Maternal Anti-HLA Class I Antibodies in Fetal and Neonatal Thrombocytopenia – Antibody Specificity Analysis Using Epitope Data
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 26, 2017 Category: Allergy & Immunology Authors: Jesper Dahl, Erle Refsum, Maria Therese Ahlen, Torstein Egeland, Tore Jensen, Marte K. Viken, Tor Brynjar Stuge, Ganesh Acharya, Anne Husebekk, Bj ørn Skogen, Heidi Tiller Source Type: research
10 workshops on Immunology of preeclampsia
For the 10th issue of the « island workshops », now the Reunion Workshops, organised by Pierre Yves Robillard since the first one in Tahiti challenging the “vascular disease only” theory of pre eclampsia and introducing the primipaternity concept, we examined the reasons for considering an Immunological approach to the disease. This (brief) overview thus examines several important topics in an Immunological framework. I have chosen to present here the evolution of the main themes rather than a purely chronological vision. (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 21, 2017 Category: Allergy & Immunology Authors: Gerard Chaouat Source Type: research
Corrigendum to “What do we know about regulatory T cells and endometriosis? A systematic review” [J. Reprod. Immunol. 120 (April) (2017) 48–55]
The authors regret to publish Table 1 with incorrect values. (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 7, 2017 Category: Allergy & Immunology Authors: Isabela Bottura Leite de Barros, Helena Malvezzi, B árbara Yasmin Gueuvoghlanian-Silva, Carla Azevedo Piccinato, Luiz Vicente Rizzo, Sergio Podgaec Tags: Corrigendum Source Type: research
Vitamin D mediates the relationship between placental cathelicidin and Group B Streptococcus colonization during pregnancy
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 5, 2017 Category: Allergy & Immunology Authors: Christine C. Akoh, Eva K. Pressman, Corrie M. Whisner, Carrie Thomas, Chang Cao, Tera Kent, Elizabeth Cooper, Kimberly O. O ’Brien Source Type: research
Increased expression of toll-like receptors 2 and 9 is associated with reduced DNA methylation in spontaneous preterm labor
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 3, 2017 Category: Allergy & Immunology Authors: Scott W. Walsh, Anuja A. Chumble, Sonya L. Washington, Kellie J. Archer, Sinem E. Sahingur, Jerome F. Strauss Source Type: research
Maternal progesterone levels are modulated by maternal BMI and predict birth weight sex-specifically in human pregnancies
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 2, 2017 Category: Allergy & Immunology Authors: Anke Diemert, Janina Goletzke, Claus Barkmann, Robert Jung, Kurt Hecher, Petra Arck Source Type: research
Editorial Board
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 1, 2017 Category: Allergy & Immunology Source Type: research
Ligands of toll-like receptors 2/4 differentially alter markers of inflammation, adhesion and angiogenesis by monocytes from women with pre-eclampsia in co-culture with endothelial cells
Pre-eclampsia (PE) is characterized by an exaggerated systemic inflammatory response and generalized endothelial dysfunction. We have recently demonstrated that fibrinogen, an endogenous ligand of Toll-like receptor (TLR) 4, activates monocytes from women with pre-eclampsia (Al-ofi et al., 2014). Using an experimental co-culture model of primary human monocytes (derived from 9 women with PE (GA=33.18 ±5.8) and 9 normotensive pregnant women, NP (GA=33.15±4.0)) and human umbilical venous endothelial cells (HUVECs), we compared the effects of fibrinogen and lipopolysaccharide (LPS, bacterial ligand to TLR4) on the expressio...
Source: Journal of Reproductive Immunology - May 24, 2017 Category: Allergy & Immunology Authors: Ebtisam A. Al-ofi, Dilly O. Anumba Source Type: research
The effect of elevated progesterone levels before oocyte retrieval in women undergoing ovarian stimulation for IVF treatment on the genomic profile of peri-implantation endometrium
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - May 17, 2017 Category: Allergy & Immunology Authors: Liu Liu, Jin Huang, Tin Chiu Li, Xu Tao Hong, Susan Laird, Yong Dong Dai, Xiao Mei Tong, Hai Yan Zhu, Songying Zhang Source Type: research
Induction of experimental autoimmune orchitis by immunization with xenogenic testicular germ cells in mice
Haploid germ cells (spermatids and spermatozoa) develop in the testis after immune tolerance has been established, therefore they contain various autoimmunogenic antigens. Experimental autoimmune orchitis (EAO) is a model of immunological male infertility. We previously established that two subcutaneous injections of viable syngeneic or allogeneic testicular germ cells (TGC) can induce CD4+T cell-dependent EAO in both A/J and C3H/He mice at a very high incidence (Itoh et al., 1991a; Tokunaga et al., 1993). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - April 27, 2017 Category: Allergy & Immunology Authors: Ning Qu, Hayato Terayama, Yoshie Hirayanagi, Miyuki Kuramasu, Yuki Ogawa, Shogo Hayashi, Shuichi Hirai, Munekazu Naito, Masahiro Itoh Source Type: research
Pregnancy favors the expansion of circulating functional follicular helper T Cells
Human follicular helper T (TFH) cells represent a distinct subset of CD4+ T cells found in secondary lymphoid organs and characterized by a high expression of the transcription factor B cell lymphoma-6 (Bcl-6), programmed cell death receptor-1 (PD-1), inducible T-cell co-stimulator (ICOS) and chemokine receptor CXCR5 associated with high IL-21 cytokine secretion (Crotty, 2011). The high expression of CXCR5, associated with low levels of CCR7, allows these lymphocytes to migrate toward lymph node follicles in a CXCL13-dependent manner (Johnston et al., 2009). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - April 26, 2017 Category: Allergy & Immunology Authors: Clarice Monteiro, Taissa M. Kasahara, Jos é Roberto Castro, Priscila Mendonça, Joana Hygino, Newton Centurião, Tatiane Cassano, Lana M. Ferreira Lopes, Simone Leite, Vander Guimarães Silva, Sudhir Gupta, Cleonice A.M. Bento Source Type: research
Treating normal early gestation placentae with preeclamptic sera produces extracellular micro and nano vesicles that activate endothelial cells
Preeclampsia is a pregnancy-specific hypertensive disorder that can lead to multiorgan failure and is a leading cause of maternal and perinatal morbidity and mortality globally (Sibai et al., 2005). The aetiology of preeclampsia is unknown and the clinical signs become apparent only after 20 weeks of gestation or, more rarely, within the first 4 –6 weeks postpartum (Staff et al., 2013). Although the pathogenic processes leading to preeclampsia are still unclear, it is well-known that the condition is triggered by a toxic factor from the placenta and extracellular vesicles (EVs) extruded, from the placental syncytiotropho...
Source: Journal of Reproductive Immunology - April 14, 2017 Category: Allergy & Immunology Authors: Xirong Xiao, Fengyi Xiao, Mingzhi Zhao, Mancy Tong, Michelle R. Wise, Peter R. Stone, Lawrence W. Chamley, Qi Chen Source Type: research
Natural killer cell activity in women with recurrent miscarriage: Etiology and pregnancy outcome
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - April 13, 2017 Category: Allergy & Immunology Authors: Yasuhiko Ebina, Yukari Nishino, Masashi Deguchi, Yoko Maesawa, Yuki Nakashima, Hideto Yamada Source Type: research
“What do we know about regulatory T cells and endometriosis? A systematic review”
Endometriosis is a benign, chronic inflammatory disease defined by the presence and development of endometrial tissue outside the uterine cavity (Vercellini et al., 2014). Although it is a prevalent disease that affects about 10% of reproductive age women, its exact etiopathogenesis remain unknown (Ahn et al., 2015). Many theories have been proposed to explain the development of endometriosis and one of the most accepted is the retrograde menstruation theory (Sampson, 1927). However, as this phenomenon occurs in 90% of women and only 10% develop endometriosis, it has been proposed a complementary theory by which defective ...
Source: Journal of Reproductive Immunology - April 10, 2017 Category: Allergy & Immunology Authors: Isabela Bottura Leite de Barros, Helena Malvezzi, B árbara Yasmin Gueuvoghlanian-Silva, Carla Azevedo Piccinato, Luiz Vicente Rizzo, Sergio Podgaec Tags: Review article Source Type: research
“What do we know about regulatory T cells and endometriosis? A systematicreview”
Endometriosis is a benign, chronic inflammatory disease defined by the presence and development of endometrial tissue outside the uterine cavity (Vercellini et al., 2014). Although it is a prevalent disease that affects about 10% of reproductive age women, itsexactetiopathogenesis remain unknown (Ahn et al., 2015). Many theories have been proposed to explain the development of endometriosis and one of the most accepted is the retrograde menstruation theory (Sampson, 1927). However, as this phenomenonoccurs in 90% of women and only 10% develop endometriosis, it has been proposed a complementary theory by which defective imm...
Source: Journal of Reproductive Immunology - April 10, 2017 Category: Allergy & Immunology Authors: Isabela Bottura Leite de Barros, Helena Malvezzi, Barbara Yasmin Gueuvoghlanian-Silva, Carla de Azevedo Piccinato, Luiz Vicente Rizzo, Sergio Podgaec Source Type: research
