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Early trauma and lifetime suicidal behavior in a nationwide sample of Korean medical studentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: No previous study has investigated the association between early trauma and suicidal behavior in medical students. We evaluated the types of early trauma which are the most strongly associated with a lifetime history of suicidal behavior in medical students.Method: A total of 6986 medical students completed a self-administered questionnaire (response rates: 49.6% of the entire medical student body in Korea) which included lifetime suicidal behavior, stressors, and the Early Trauma Inventory Self Report-Short Form (ETISR-SF). This was used to evaluate the most serious forms of trauma experienced before...
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Hong Jin Jeon, Myoung-Sun Roh, Kyu-Han Kim, Jeong-Ryul Lee, Dongsoo Lee, Se Chang Yoon, Bong-Jin Hahm Tags: Brief reports Source Type: journals

Harm avoidance moderates the influence of serotonin transporter gene variants on treatment outcome in bipolar patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Response to pharmacological treatments is moderated by both genetic and environmental factors. The contribution of such factors is relatively small and complex interactions are likely to be involved. Serotonin transporter gene (SLC6A4) is a major candidate gene associated to response to antidepressant treatment. Moreover, the 5-HTTLPR polymorphism has been associated with anxiety-related traits such as neuroticism and harm avoidance (HA), which are known to influence the risk to develop mood disorders and response to treatments. In the present study we aimed to investigate the interaction between 3 SLC6A4 variant...
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Laura Mandelli, Marianna Mazza, Giovanni Martinotti, Marco Di Nicola, Daniela Tavian, Elisa Colombo, Sara Missaglia, Diana De Ronchi, Roberto Colombo, Luigi Janiri, Alessandro Serretti Tags: Brief reports Source Type: journals

Posttraumatic stress disorder after childbirth: Analysis of symptom presentation and samplingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Results emphasise the importance of measuring full diagnostic criteria in postnatal samples, as reports of symptoms may be inflated. In addition a few risk factors are identified that could be used to screen for women at risk. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Ayers Susan, Rachel Harris, Alexandra Sawyer, Ylva Parfitt, Elizabeth Ford Tags: Brief reports Source Type: journals

Early discontinuation of antidepressant treatment and suicide risk among persons aged 50 and over: A population-based register studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: We did not find a lower suicide risk among people over age 50 who seemingly follow treatment in comparison with those who discontinued treatment with antidepressants at an early stage. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Annette Erlangsen, Esben Agerbo, Keith Hawton, Yeates Conwell Tags: Brief reports Source Type: journals

Does a psychoeducational approach reach targeted patients with bipolar disorder?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions:: Our results suggest motivation and participation rates of patients who attended a psychoeducation program were constrained. Factors associated with a poor response to psychopharmacologic treatments also seem valid for non-attendance to the psychological interventions. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Sibel Cakir, Rakel Bensusan, Zeynep K. Akca, Olcay Yazici Tags: Brief reports Source Type: journals

Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The normal glutamatergic measures combined with elevated levels of the astrocytic marker, myo-inositol, suggest that recovery from depression may be associated with changes in glial function in frontal cortex. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Matthew J. Taylor, Sudhakar Selvaraj, Ray Norbury, Peter Jezzard, Philip J. Cowen Tags: Brief reports Source Type: journals

Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The data suggest that there is considerable overlap in symptom expression between cytokine-induced depression and idiopathic depression in medically healthy subjects. Nevertheless, differences in isolated symptom domains suggest that cytokines may preferentially target neurocircuits relevant to psychomotor activity (e.g. basal ganglia), while having a limited effect on cognitive distortions regarding self-appraisal. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Lucile Capuron, Fiona B. Fornwalt, Bettina T. Knight, Philip D. Harvey, Philip T. Ninan, Andrew H. Miller Tags: Brief reports Source Type: journals

Affective disorders and other psychiatric diagnoses in children and adolescents with 22q11.2 Deletion SyndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Affective, anxiety, attentional, and behavioral disorders were relatively common in this randomly selected group of children and adolescents with 22qDS. No child met criteria for bipolar disorder or schizophrenia. Prospective, longitudinal study is needed to determine whether early psychiatric symptomatology in children with 22qDS predicts continuing or more severe psychopathology later in life. Early psychiatric screening and monitoring appears warranted in 22qDS patients. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Edith M. Jolin, Ronald A. Weller, Naushad R. Jessani, Elaine H. Zackai, Donna M. McDonald-McGinn, Elizabeth B. Weller Tags: Brief reports Source Type: journals

Healthcare utilization patterns before and after contact with psychiatrist care for panic disorderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study aimed to examine healthcare utilization and expenditures in the six months before and after a patient contacted with psychiatrist care for panic disorder (PD), using a nationwide population-based database in Taiwan.Methods:: We used data from Taiwan's National Health Insurance Research Database covering the years 2002 to 2005. Our study sample included 15,374 patients with PD. We compare changes in the number of ER and outpatient visits and associated six months before and after a patient received psychiatric treatment for PD, by performing paired t-tests.Results:: Results indicate that despite increased mean nu...
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Yi-Hua Chen, Shu-Fen Chen, Herng-Ching Lin, Hsin-Chien Lee Tags: Brief reports Source Type: journals

Primary care patients with anxiety and depression: Need for care from the patient's perspectiveEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Although no conclusions can be made about what type of care was specifically not wanted, patients with anxiety or depression mostly want to receive information and counselling. Health professionals should be aware of the fact that there are differences in perceived need for care between subgroups of patients, based on their beliefs and their evaluation of care. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Marijn A. Prins, Peter F.M. Verhaak, Klaas van der Meer, Brenda W.J.H. Penninx, Jozien, M. Bensing Tags: Research reports Source Type: journals

Impaired implicit learning and reduced pre-supplementary motor cortex size in early-onset major depression with melancholic featuresEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions:: Deficits in implicit motor sequence learning seem to be an additional characteristic of the melancholic subtype of depression. It might be linked to dysfunction within structural or functionally altered frontostriatal circuits. Use of implicit sequence learning tasks could offer useful diagnostic and aetiological cues for future research. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Cornelia Exner, Claudia Lange, Eva Irle Tags: Research reports Source Type: journals

Demonstration of disturbed activity of external globus pallidus projecting neurons in depressed patients by the AgNOR staining methodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The results suggest disturbed, most likely decreased, activity of the left EGP projecting neurons in depressed patients, a disturbed activity that should hypothetically be counteracted by the applied pharmacotherapy in non-suicidal patients. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Tomasz Gos, Dieter Krell, Hendrik Bielau, Johann Steiner, Kurt Trübner, Ralf Brisch, Hans-Gert Bernstein, Zbigniew Jankowski, Bernhard Bogerts Tags: Research reports Source Type: journals

Anxiety and depression during pregnancy in women and menEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Different time variation in pregnancy was found for anxiety and depression symptoms; however anxiety and depression symptoms are particularly high during the 1st trimester. Intervention needs will be analyzed according to the results. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: César Teixeira, Bárbara Figueiredo, Ana Conde, Alexandra Pacheco, Raquel Costa Tags: Research reports Source Type: journals

Serotonin transporter polymorphisms, microstructural white matter abnormalities and remission of geriatric depressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Lower FA was observed in several frontolimbic and other regions in depressed elders compared to controls. Depressed S-allele carriers had both microstructural white matter abnormalities in frontolimbic networks and a low remission rate. It remains unclear whether the risk for chronicity of geriatric depression in S-allele carriers is mediated by frontolimbic compromise. However, these observations set the stage for studies aiming to identify the relationship of S allele to impairment in specific frontolimbic functions interfering with response of geriatric depression to antidepressants. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: George S. Alexopoulos, Christopher F. Murphy, Faith M. Gunning-Dixon, Charles E. Glatt, Vassilios Latoussakis, Robert E. Kelly, Dora Kanellopoulos, Sibel Klimstra, Kelvin O. Lim, Robert C. Young, Matthew J. Hoptman Tags: Research reports Source Type: journals

Functional MRI study of memory-related brain regions in patients with depressive disorderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The current study suggests that depression is associated with modified memory-related brain function. In particular the parahippocampal gyrus, the prefrontal cortex and parietal regions show functional alterations during associative learning. These structures as well as their interrelationships may play an important role in the pathogenesis of depressive disorder. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Natalie S. Werner, Thomas Meindl, Julia Materne, Rolf R. Engel, Dorothea Huber, Michael Riedel, Maximilian Reiser, Kristina Hennig-Fast Tags: Research reports Source Type: journals

The impact of postnatal and concurrent maternal depression on child behaviour during the early school yearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Findings confirm the importance of early identification and treatment for mothers with postnatal depression, given the likelihood of ongoing depression and relations with later child behaviour problems. From a practical point, severity of early symptoms may be a reliable index of those mothers and children at greatest risk. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Irene Fihrer, Catherine A. McMahon, Alan J. Taylor Tags: Research reports Source Type: journals

Interaction between genetic polymorphisms and stressful life events in first episode depressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Polymorphisms in the genes encoding the serotonin transporter and the brain derived neurotrophic factor interact with recent stressful life events on depression among patients with no history of previous depressive episodes. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Jens Drachmann Bukh, Camilla Bock, Maj Vinberg, Thomas Werge, Ulrik Gether, Lars Vedel Kessing Tags: Research reports Source Type: journals

Depressive symptomatology is influenced by chronotypesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our data suggest the idea that chronotypes have an impact on depressive episodes features, with higher severity for the eveningness-type. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Enrique Gaspar-Barba, Raffaella Calati, Carlos S. Cruz-Fuentes, Martha P. Ontiveros-Uribe, Vincenzo Natale, Diana De Ronchi, Alessandro Serretti Tags: Research reports Source Type: journals

Abnormal response to failure in unmedicated major depressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The abnormal response to negative feedback previously identified in depressed samples was replicated in the current unmedicated, less severely depressed group. The impairment shown in the depressed sample may be due to a reduction in the motivating effect of an error compared with healthy controls. This has possible relevance to both neurobiological and psychological theories of depression. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Katie M. Douglas, Richard J. Porter, Christopher M. Frampton, Peter Gallagher, Allan H. Young Tags: Research reports Source Type: journals

Negative mood and sexual behavior among non-monogamous men who have sex with men in the context of methamphetamine and HIVEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: METH dependence, HIV seropositivity, and negative moods are associated with reduced condom use among non-monogamous MSM. Independent effects of METH dependence and negative mood on condom use suggest that sexual risk reduction interventions for MSM should incorporate multi-faceted approaches, including substance abuse and mental health treatment. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: C.A. Bousman, M. Cherner, C. Ake, S. Letendre, J.H. Atkinson, T.L. Patterson, I. Grant, I.P. Everall, The HNRC Group Tags: Research reports Source Type: journals

Social anxiety disorder in older adults: Evidence from the National Epidemiologic Survey on alcohol and related conditionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The correlation between social anxiety disorder and MDD raises further questions about the nature of social anxiety disorder among older adults, but this study does not support the notion that this disorder has a strong impact on the quality of life in old age independent of other psychiatric comorbidities. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Kee-Lee Chou Tags: Research reports Source Type: journals

Appraisals of stressors and common mental disorder from early to mid-adulthood in the 1946 British birth cohortEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Appraisals of changes following stressful life events may be more important than the occurrence of stressors alone in assessing the impact of stressful life events on adult mental health. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Stephani L. Hatch, Gita Mishra, Matthew Hotopf, Peter B. Jones, Diana Kuh Tags: Research reports Source Type: journals

Seasonality of suicide in Sweden: Relationship with psychiatric disorderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: A history of inpatient-treated psychiatric disorder appears to be associated with an increase in suicide seasonality, especially in violent suicide methods. This increase is found in several psychiatric disorders. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Johan Reutfors, Urban Ösby, Anders Ekbom, Peter Nordström, Jussi Jokinen, Fotios C. Papadopoulos Tags: Research reports Source Type: journals

Prevalence and comorbidity of common mental disorders in primary careEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The study provides further evidence of the high prevalence and high comorbidity of mental disorders in primary care. Given the large overlap between affective, anxiety and somatoform disorders, future diagnostic classifications should reconsider the current separation between these entities. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: M. Roca, M. Gili, M. Garcia-Garcia, J. Salva, M. Vives, J. Garcia Campayo, A. Comas Tags: Research reports Source Type: journals

The clinical effect of clomipramine in chronic idiopathic pain disorder revisited using the Spielberger State Anxiety Symptom Scale (SSASS) as outcome scaleEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In patients with chronic non-malignant pain, clomipramine is superior to placebo as regards anxiolytic effect measured by Spielberger State Anxiety Symptom Scale (SSASS). No pure analgesic effect was demonstrated. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Per Bech, Lise Gormsen, Dorte Loldrup, Marianne Lunde Tags: Research reports Source Type: journals

Personality profiles and minor affective psychopathology in a non-clinical sample: An empirical verification of Cloninger's theoretical modelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: It is possible to identify certain personality configurations associated with minor psychopathology and concomitant use of psychotropics, among active professional people. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Manuel Gurpegui, Dolores Jurado, M. Carmen Fernández-Molina, Obdulia Moreno-Abril, Juan D. Luna, Renato D. Alarcón Tags: Research reports Source Type: journals

Predominant polarity and temperament in bipolar and unipolar affective disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study enrolled 143 patients with bipolar or unipolar disorder. We analysed predominant polarity in the sample of bipolar I patients (N=124), focussing on those who showed a clear predominance for one or the other polarity, and distinguishing manic/hypomanic (MP) from depressive polarity (DP), and a unipolar major depression (UP) group (N=19),. We also assessed temperament by means of the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A).Results: Over 55% of the bipolar I sample fulfilled predominant polarity criteria, with two-thirds of those meeting criteria for MP and one ...
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Lorenzo Mazzarini, Isabella Pacchiarotti, Francesc Colom, Gabriele Sani, Giorgio D. Kotzalidis, Adriane R. Rosa, Livia Sanna, Pietro De Rossi, Nicoletta Girardi, C. Mar Bonnin, Jose Sanchez-Moreno, Gustavo H. Vazquez, Cristobal Gasto, Roberto Tatarelli, E Tags: Research reports Source Type: journals

Predominant previous polarity as an outcome predictor in a controlled treatment trial for depression in bipolar I disorder patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Predominant previous depressive>manic episodes selectively yielded poorer responses of BPD to treatment for acute BP depression, particularly in men. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: E. Vieta, M. Berk, W. Wang, F. Colom, M. Tohen, R.J. Baldessarini Tags: Research reports Source Type: journals

Risk for switch from unipolar to bipolar disorder in youth with ADHD: A long term prospective controlled studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: ADHD is a risk factor for switches from unipolar to bipolar disorder, and switches could be predicted by the presence of baseline conduct disorder, school behavior problems, and a positive family history of a mood disorder in a parent. These characteristics can aid clinicians in their treatment of youth with MDD. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Joseph Biederman, Carter R. Petty, Deirdre Byrne, Patricia Wong, Janet Wozniak, Stephen V. Faraone Tags: Research reports Source Type: journals

Toward a functional neuroanatomy of dysthymia: A functional magnetic resonance imaging studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The findings suggest the involvement of the prefrontal cortex, anterior cingulate, amygdala, and insula in the neural circuitry underlying dysthymia. It is suggested that altered activation in some of these neural regions may be a common substrate for depressive disorders in general while others may relate specifically to symptom characteristics and the chronic course of dysthymia. These findings are particularly striking given the history of this deceptively mild disorder which is still confused by some with character pathology. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Arun V. Ravindran, Andra Smith, Colin Cameron, Raj Bhatla, Ian Cameron, Tania M. Georgescu, Matthew J. Hogan Tags: Special research report Source Type: journals

A meta-analysis of depression severity and cognitive functionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The results suggest that previous inconsistent findings of the relationship between the severity of depression and cognitive function may be attributed to random variations and lack of power within studies. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Authors: Lisa M. McDermott, Klaus P. Ebmeier Tags: Review Source Type: journals

Editorial BoardEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - October 16, 2009 Category: Neurology Source Type: journals

Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly ChineseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Depressive symptoms are not associated with 25(OH)D concentrations in middle-aged and elderly Chinese. Further prospective studies are required to determine whether they are correlated. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: An Pan, Ling Lu, Oscar H. Franco, Zhijie Yu, Huaixing Li, Xu Lin Tags: Brief reports Source Type: journals

Global leukocyte DNA methylation is not altered in euthymic bipolar patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The lack of difference in leukocyte global DNA methylation between euthymic bipolar patients and healthy controls does not rule out the possibility that altered methylation of specific promoter regions is involved in the etiology of the disorder. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: A. Bromberg, Y. Bersudsky, J. Levine, G. Agam Tags: Brief reports Source Type: journals

A study of age at onset and affective temperaments in a Norwegian sample of patients with mood disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: Early age at onset of bipolar disorder is clinically important since it predicts a more severe course of illness and a poorer prognosis. Recently the age at onset (AAO) of bipolar disorder (BPD) has been reported different in samples from the USA and Europe (Bipolar Collaborative Network). We have examined the AAO of first major affective episode in major depressive disorder (MDD) and bipolar disorder in a sample of patients consecutively admitted to an affective ward in Norway. We also examined the relation between AAO and affective temperaments.Methods: Semi-structured interview of 119 patients cons...
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Ketil J. Oedegaard, Vigdis E.G. Syrstad, Gunnar Morken, Hagop S. Akiskal, Ole B. Fasmer Tags: Brief reports Source Type: journals

Use of lithium in the adult populations of Denmark, Norway and SwedenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: This study is the first attempt to use prescription databases in all three Scandinavian countries to describe in detail the epidemiology of a drug's use. The analysis revealed subtle differences in the clinical use of lithium that cannot be explained by differences in the epidemiology of bipolar disorder. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Jørgen G. Bramness, Gunilla Ringbäck Weitoft, Jesper Hallas Tags: Brief reports Source Type: journals

Difference in prevalence of common mental disorder as measured using four questionnaire delivery methods among young people in rural ZimbabweEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report here on differences in prevalence of reporting mental health between four questionnaire delivery modes (QDM).Methods: Mental health was assessed using the Shona Symptom Questionnaire (SSQ), a locally validated 14-item indigenous measure for common mental affective disorders. A representative sample of 1495 rural Zimbabwean adolescents (median age 18) was randomly allocated to one of four questionnaire delivery modes: self-administered questionnaire (SAQ), SAQ with audio (AASI), interviewer-administered questionnaire (IAQ), and audio computer-assisted survey instrument (ACASI).Results: Prevalence of common affecti...
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Lisa F. Langhaug, Yin Bun Cheung, Sophie Pascoe, Richard Hayes, Frances M. Cowan Tags: Brief reports Source Type: journals

Transcranial direct current stimulation in severe, drug-resistant major depressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: We conclude that frontal tDCS is a simple, promising technique that can be considered in clinical practice as adjuvant treatment for hospitalized patients with severe, drug-resistant major depression. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: R. Ferrucci, M. Bortolomasi, M. Vergari, L. Tadini, B. Salvoro, M. Giacopuzzi, S. Barbieri, A. Priori Tags: Brief reports Source Type: journals

Plasma phospholipid fatty acid status and depressive symptoms: Association only present in the clinical rangeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study offers a first indication that a suboptimal LCPUFA status might accompany depressive symptoms primarily within the clinical spectrum. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Olga J.G. Schiepers, Renate H.M. de Groot, Jelle Jolles, Martin P.J. van Boxtel Tags: Brief reports Source Type: journals

Ziprasidone monotherapy in bipolar II depression: An open trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Ziprasidone at a relatively low dose appears to be a rapid, effective and generally well tolerated treatment for bipolar II patients experiencing major depression. However, larger, placebo-controlled trials are needed to confirm these findings. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Michael R. Liebowitz, Ester Salmán, Arnold Mech, David Dunner, Ann E. Johnson, Jamil Akhtar, Rajiv Pratap Tags: Brief reports Source Type: journals

Complicated grief in patients with unipolar depressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Comorbid complicated grief appears to contribute to greater severity and poorer functioning in unipolar depressed patients and should be specifically addressed in psychotherapeutic treatment. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Anette Kersting, Kristin Kroker, Julia Horstmann, Patricia Ohrmann, Bernhard T. Baune, Volker Arolt, Thomas Suslow Tags: Brief reports Source Type: journals

Methods of suicide in different psychiatric diagnostic groupsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Suicide victims with different psychiatric diagnoses vary in their choice of suicide methods. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Ying-Yeh Chen, Ming-Been Lee, Chia-Ming Chang, Shih-Cheng Liao Tags: Brief reports Source Type: journals

Zinc supplementation augments efficacy of imipramine in treatment resistant patients: A double blind, placebo-controlled studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Zinc supplementation augments the efficacy and speed of onset of therapeutic response to imipramine treatment, particularly in patients previously nonresponsive to antidepressant pharmacotherapies.These data suggest the participation of disturbed zinc/glutamatergic transmission in the pathophysiology of drug resistance. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Marcin Siwek, Dominika Dudek, Ian A. Paul, Magdalena Sowa-Kućma, Andrzej Zięba, Piotr Popik, Andrzej Pilc, Gabriel Nowak Tags: Research reports Source Type: journals

Perceived stigma among individuals with common mental disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: Severe mental disorders are associated with social distance from the general population, but there is lack of data on the stigma reported by individuals with common mental disorders.Aims: To identify the correlates and the impact of stigma among individuals with common mental disorders.Methods: Cross-sectional, household interview survey of 8796 representing the non-institutionalized adults of Belgium, France, Germany, Italy, the Netherlands and Spain. Two perceived stigma questions (embarrassment and discrimination) were asked to respondents with significant disability. Health-related quality of life...
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Jordi Alonso, Andrea Buron, Sonia Rojas-Farreras, Ron de Graaf, Josep Mª Haro, Giovanni de Girolamo, Ronny Bruffaerts, Viviane Kovess, Herbert Matschinger, Gemma Vilagut, for the ESEMeD/MHEDEA 2000 Investigators Tags: Research reports Source Type: journals

Lifetime psychiatric disorders and body composition: A population-based studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Depression was associated with greater adiposity. The difference in body fat mass was numerically greater than differences in indirect measures of adiposity, suggesting that the latter may underestimate the extent of adiposity in this population. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Lana J. Williams, Julie A. Pasco, Margaret J. Henry, Felice N. Jacka, Seetal Dodd, Geoffrey C. Nicholson, Mark A. Kotowicz, Michael Berk Tags: Research reports Source Type: journals

A longitudinal analysis of alcohol consumption and the risk of posttraumatic symptomsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Given the potential impact of alcohol use on traumatic injury and post-injury recovery, we advocate active screening and early intervention strategies that focus on moderate alcohol usage. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: A.C. McFarlane, D. Browne, R.A. Bryant, M. O'Donnell, D. Silove, M. Creamer, K. Horsley Tags: Research reports Source Type: journals

Development and use of a biological rhythm interviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes the validation of a new instrument, the Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN), designed to assess biological rhythms in the clinical setting.Methods: Eighty-one outpatients with a diagnosis of bipolar disorder and 79 control subjects matched for type of health service used, sex, age and educational level were consecutively recruited. After a pilot study, 18 items evaluating sleep, activities, social rhythm and eating pattern were probed for discriminant, content and construct validity, concurrent validity with the Pittsburgh Sleep Quality Index (PSQI), internal consiste...
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Larriany Maria Falsin Giglio, Pedro Vieira da Silva Magalhães, Ana Cristina Andreazza, Julio Cesar Walz, Lourenço Jakobson, Paola Rucci, Adriane Ribeiro Rosa, Maria Paz Hidalgo, Eduard Vieta, Flávio Kapczinski Tags: Research reports Source Type: journals

Abnormal temperament in patients with morbid obesity seeking surgical treatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our results need replication but indicate an affective overlap in the form of abnormal temperament and depressive symptoms in obese patients, whereas mood swings should be evaluated and early mood stabilization considered for patients with significant weight gain to prevent obesity or to reduce already existing overweight. Studies of mood stabilizers and prospective observations would shed further insight on this complex interface of a major clinical and public health issue. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Benedikt Amann, Roland Mergl, Carla Torrent, Giulio Perugi, Frank Padberg, Nadja El-Gjamal, Gregor Laakmann Tags: Research reports Source Type: journals

Body weight as a predictor of antidepressant efficacy in the GENDEP projectEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Body weight should be considered in the assessment of depression as it may inform the selection of antidepressant treatment. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Rudolf Uher, Ole Mors, Joanna Hauser, Marcella Rietschel, Wolfgang Maier, Dejan Kozel, Neven Henigsberg, Daniel Souery, Anna Placentino, Nader Perroud, Moica Zvezdana Dernovsek, Jana Strohmaier, Erik Roj Larsen, Astrid Zobel, Anna Leszczynska-Rodziewicz, Tags: Research reports Source Type: journals

Patient-rated troubling symptoms of depression instrument results correlate with traditional clinician- and patient-rated measures: A secondary analysis of a randomized, double-blind, placebo-controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: The Patient-Rated Troubling Symptoms of Depression (PaRTS-D) instrument assesses the presence and troublesomeness of 8 commonly reported depression-related symptoms from the patient's perspective. A post hoc analysis of a double-blind, randomized risperidone augmentation to antidepressant therapy trial in patients with major depressive disorder explored the relationship between the PaRTS-D instrument and other clinician- and patient-rating scales.Methods: Patients completed the PaRTS-D; the Patient Global Improvement Scale (PGIS), Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), and...
Source: Journal of Affective Disorders - September 14, 2009 Category: Neurology Authors: Gahan J. Pandina, Dennis A. Revicki, Leah Kleinman, Ibrahim Turkoz, Jasmanda H. Wu, Mary J. Kujawa, Ramy Mahmoud, Georges M. Gharabawi Tags: Research reports Source Type: journals