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An Anterior Ablation Line Is Preferred for Perimitral Flutter After Heart TransplantEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report 2 cases where an anterior ablation line was easily performed to eliminate perimitral flutter and produce bidirectional block. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]3) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 18, 2009 Category: Cardiology Authors: BHAVANESH MAKANJEE, GEORGE J. KLEIN, NICHOLAS DERVAL, ALLAN C. SKANES Source Type: journals

Validation of Coronary Sinus Activation Pattern During Left Atrial Appendage Pacing for Beat-to-Beat Assessment of Mitral Isthmus Conduction/BlockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Assessment of Mitral Isthmus. Introduction: Mitral isthmus (MI) ablation for treatment of perimitral flutter is often performed during atrial fibrillation (AF) ablation but is technically challenging. Traditional assessment of MI conduction by left atrial activation mapping while pacing from either side of the line is time-consuming, and cannot be performed during ongoing ablation. Analysis of the coronary sinus (CS) activation pattern during left atrial appendage (LAA) pacing has been proposed as a simpler technique for evaluating MI conduction, enabling beat-to-beat assessment of conduction during ablation procedures and...
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: JOHN PAISEY, TIM R. BETTS, JOSEPH DE BONO, KIM RAJAPPAN, DAVID TOMLINSON, YAVER BASHIR Source Type: journals

Long-Term Functional and Neurocognitive Recovery in Patients Who Had an Acute Cerebrovascular Event Secondary to Catheter Ablation for Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Periprocedural stroke in the setting of catheter ablation for atrial fibrillation is relatively rare. When it occurs, complete functional and neurocognitive recovery over time is the likely outcome for most patients. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: DIMPI PATEL, SHANE M. BAILEY, ANTHONY J. FURLAN, MARILOU CHING, JONATHAN ZACHAIB, LUIGI DI BIASE, PRASANT MOHANTY, RODNEY P. HORTON, J. DAVID BURKHARDT, JAVIER E. SANCHEZ, JASON D. ZAGRODZKY, G. JOSEPH GALLINGHOUSE, ROBERT SCHWEIKERT, WALID SALIBA, ANDREA Source Type: journals

Clinical Performance of the St. Jude Medical Riata Defibrillation Lead in a Large Patient PopulationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
. Objective: The purpose of this large multicenter study was to evaluate the long-term reliability of an implantable cardioverter defibrillator (ICD) lead to determine the incidence of adverse events (AEs). Background: A recent concern has been the performance of cardiac defibrillator leads. There have been conflicting reports regarding the rate of lead perforation and other AEs. Methods: Medical records from patients implanted from 6-1-2001 to 11-27-2007 with the St. Jude Medical Riata family of RV leads at 23 US (N = 12,969) and 5 German (N = 2,418) centers were reviewed for chronic lead-related AEs. These included perfo...
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: JAMES G. PORTERFIELD, LINDA M. PORTERFIELD, KARL H. KUCK, RAFFAELE CORBISIERO, STEVEN M. GREENBERG, GERHARD HINDRICKS, OUSSAMA WAZNI, SCOTT L. BEAU, JOHN M. HERRE Source Type: journals

Performance of a Radiation Protection Cabin During Implantation of Pacemakers or Cardioverter DefibrillatorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The use of a radiation protection cabin markedly decreased the exposure of the operator to radiation, and eliminated the need to wear a lead apron, without increasing the procedural time or complication rate during implantation of pacemaker and ICD. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: SYLVAIN PLOUX, PHILIPPE RITTER, MICHEL HAÏSSAGUERRE, JACQUES CLEMENTY, PIERRE BORDACHAR Source Type: journals

A Prospective Study Evaluating the Role of Obesity and Obstructive Sleep Apnea for Outcomes After Catheter Ablation of Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Effect of Obesity and OSA on Outcomes Post AF Ablation. Background: Obesity and obstructive sleep apnea (OSA) have a strong association with atrial fibrillation (AF). The purpose of this study was to prospectively determine the effects of obesity, assessed by the body mass index (BMI) and OSA on the efficacy of catheter ablation of AF. Methods: The patient population consisted of 109 patients (mean age: 60 ± 10 years, 79% male, 67% paroxysmal, mean BMI 28 ± 5 kg/m2) who underwent catheter ablation of AF. Based on BMI, patients were classified as normal ( (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: KARUNA CHILUKURI, DARSHAN DALAL, SHRIRANG GADREY, JOSEPH E. MARINE, EDWIN MACPHERSON, CHARLES A. HENRIKSON, ALAN CHENG, SAMAN NAZARIAN, SUNIL SINHA, DAVID SPRAGG, RONALD BERGER, HUGH CALKINS Source Type: journals

Safety of Deferring the Reimplantation of Pacing Systems After Their Removal for Infectious Complications in Selected Patients: A 1-Year Follow-Up StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Introduction: Recent expert consensus guidelines mention that one of the principles for infected device replacement following removal is to "reevaluate carefully if there is a continued need for a new cardiac device replacement." This is a Class I recommendation, which nevertheless suffers from a very low level of evidence (level of evidence C), since no study has revisited the systematic practice of reimplanting the same device based on a meticulous clinical reassessment. In the present paper, we examined the safety of withholding the implantation of pacing systems in selected patients. Methods and Results: Between Januar...
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: ELOI MARIJON, MAXIME DE GUILLEBON, PIERRE BORDACHAR, SOPHIE JACOB, OLIVIER VAHDAT, LAURENT SIDOBRE, ANTOINE DEPLAGNE, NICOLAS COMBES, JEAN-PAUL ALBENQUE, JACQUES CLEMENTY, MICHEL HAISSAGUERRE, PHILIPPE RITTER, SERGE BOVEDA Source Type: journals

A Prospective Randomized Multicenter Comparison on Health-Related Quality of Life: The Value of Add-on Arrhythmia Surgery in Patients with Paroxysmal, Permanent or Persistent Atrial Fibrillation Undergoing Valvular and/or Coronary Bypass SurgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Health-related quality of life in patients with paroxysmal, permanent and persistent atrial fibrillation improves after cardiac surgery regardless of giving add-on surgery or not, but this improvement is presumably more affected by treating the underlying heart disease than by restoring sinus rhythm. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]10) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: H. N. A. M. VAN BREUGEL, F. H. M. NIEMAN, R. E. ACCORD, G. A. P. G. VAN MASTRIGT, J. F. M. A. NIJS, J. L. SEVERENS, R. VRAKKING, J. G. MAESSEN Source Type: journals

Initial Experience Using a Radiofrequency Powered Transseptal NeedleEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: A radiofrequency powered transseptal needle can be used to perform TSP safely and successfully without the need for significant mechanical force, even in patients who have undergone TSP previously. Additional studies are needed to determine whether a powered transseptal needle should be used routinely. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]5) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: MATTHEW P. SMELLEY, DIPAK P. SHAH, IAN WEISBERG, SUSAN S. KIM, ALBERT C. LIN, JOHN F. BESHAI, MARTIN C. BURKE, BRADLEY P. KNIGHT Source Type: journals

Defibrillator Implantation in the Elderly: Patients Are Older, But Are Physicians Wiser?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 13, 2009 Category: Cardiology Authors: STEVEN M. MARKOWITZ Source Type: journals

High-Density Mapping of the Sinus Node in Humans: Role of Preferential Pathways and the Effect of RemodelingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The functional sinus node complex demonstrates dynamic changes in activation. There are preferential pathways of conduction from sinus node to atrial myocardium. The remodeled atria demonstrate longer conduction times along preferential pathways and a restricted functional sinus node complex. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]8) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Authors: MARTIN K. STILES, ANTHONY G. BROOKS, KURT C. ROBERTS-THOMSON, PAWEL KUKLIK, BOBBY JOHN, GLENN D. YOUNG, JONATHAN M. KALMAN, PRASHANTHAN SANDERS Source Type: journals

Percutaneous Access of the Epicardial Space for Mapping Ventricular and Supraventricular Arrhythmias in Patients With and Without Prior Cardiac SurgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In patients without prior cardiac surgery, percutaneous epicardial access can be obtained in the majority of patients. Prior cardiac surgery precludes access in the most patients and when possible adhesions may limit catheter movement. Repeat access is possible in the majority of patients without the installation of intrapericardial glucocorticoid at the first procedure. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Authors: KURT C. ROBERTS-THOMSON, JENS SEILER, DANIEL STEVEN, KEIICHI INADA, GREGORY F. MICHAUD, ROY M. JOHN, BRUCE A. KOPLAN, LAURENCE M. EPSTEIN, WILLIAM G. STEVENSON, USHA B. TEDROW Source Type: journals

Triggering Pulmonary Veins: A Paradoxical Predictor for Atrial Fibrillation Recurrence After PV IsolationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Triggering Pulmonary Veins and Recurrence After Ablation. Purpose: To identify procedural parameters predicting recurrence of atrial fibrillation (AF) after a first circumferential pulmonary vein isolation (CPVI). Methods: One hundred seventy-one patients undergoing CARTO-guided CPVI for recurrent AF with a left atrial (LA) diameter (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Authors: YVES DE GREEF, RENE TAVERNIER, YVES VANDEKERCKHOVE, MATTIAS DUYTSCHAEVER Source Type: journals

Adenosine Triphosphate Exposes Dormant Superior Vena Cava Conduction Responsible for Recurrent Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Authors: SHINSUKE MIYAZAKI, ATSUSHI KOBORI, TAISHI KUWAHARA, ATSUSHI TAKAHASHI Source Type: journals

AF News: Editor: Shih-Ann Chen, M.D.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Source Type: journals

Imminent Ganglionic Ventricular Rate Control During Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 11, 2009 Category: Cardiology Authors: JACQUES BILLETTE, RAFIK TADROS Source Type: journals

The Disparities in the Electrogram Voltage Measurement During Atrial Fibrillation and Sinus RhythmEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The peak electrogram unipolar voltage during AF did not represent the voltage during SR. The RMS amplitude may be an alternative metric for voltage mapping to characterize the myocardial substrate. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 10, 2009 Category: Cardiology Authors: CHIEN-JUNG CHANG, YENN-JIANG LIN, SATOSHI HIGA, SHIH-LIN CHANG, LI-WEI LO, TA-CHUAN TUAN, YU-FENG HU, AMEYA R. UDYAVAR, WEI-HUA TANG, WEN-CHIN TSAI, SHIN-YU HUANG, NGUYEN-HUU TUNG, KAZUYOSHI SUENARI, HSUAN-MING TSAO, SHIH-ANN CHEN Source Type: journals

Impact of Tricuspid Regurgitation and Prior Coronary Bypass Surgery on the Geometry of the Coronary Sinus: A Rotational Coronary Angiography StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to examine the impact of the underlying cardiac pathology on the variability of the CS anatomy, using rotational coronary venous angiography (RCVA). Methods and Results: Seventy-nine patients undergoing RCVA for cardiac resynchronization therapy (CRT) were evaluated: age 63 ± 15 years, 43% with prior coronary artery bypass grafting (CABG). Aspects of the CS anatomy which could impact cannulation were examined: the CS ostial angle, the posterior displacement of the CS away from the atrioventricular groove, a measure of CS curvature, and the presence of stenoses and aneurysmal dilatations. Th...
Source: Journal of Cardiovascular Electrophysiology - November 10, 2009 Category: Cardiology Authors: DAN BLENDEA, E. KEVIN HEIST, SAUMYA DAS, STEPHAN DANIK, CONOR BARRETT, THEOFANIE MELA, JEREMY N. RUSKIN, JAGMEET P. SINGH Source Type: journals

Results of Short-Term and Long-Term Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation Using Duty-Cycled Bipolar and Unipolar Radiofrequency EnergyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: PV isolation by duty-cycled unipolar/bipolar RF ablation can be effectively and safely performed with a circular, decapolar catheter. Twelve-month follow-up data compare favorably with early postablation results, indicating stable effects over time. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 10, 2009 Category: Cardiology Authors: MARCUS WIECZOREK, REINHARD HOELTGEN, ELVAN AKIN, ALI REZA SALILI, HAKAN ORAL, FRED MORADY Source Type: journals

Transseptal Dispersion of Repolarization and Its Role in the Development of Torsade de Pointes ArrhythmiasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our data indicate that dispersion of repolarization across the interventricular septum is twice that of the LV free wall, predisposing to development of TdP under long-QT conditions. Our findings suggest that the coronary-perfused ventricular septal preparation may be a sensitive model in which to assess the potential arrhythmogenic effects of drugs and pathophysiological conditions. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 10, 2009 Category: Cardiology Authors: SERGE SICOURI, AARON GLASS, MARCELA FERREIRO, CHARLES ANTZELEVITCH Source Type: journals

Recurrent Torsade de Pointes During Mild Hypothermia Therapy for a Survivor of Sudden Cardiac Arrest Due to Drug-induced Long-QT SyndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 20, 2009 Category: Cardiology Authors: TOMOHIRO MATSUHASHI, TOSHIAKI SATO, YOSHIYASU AIZAWA, SEIJI TAKATSUKI Source Type: journals

Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium ChannelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cardiac Diseases Caused by SCN5A Mutations. A prerequisite for a normal cardiac function is a proper generation and propagation of electrical impulses. Contraction of the heart is obtained through a delicate matched transmission of the electrical impulses. A pivotal element of the impulse propagation is the depolarizing sodium current, responsible for the initial depolarization of the cardiomyocytes. Recent research has shown that mutations in the SCN5A gene, encoding the cardiac sodium channel Nav1.5, are associated with both rare forms of ventricular arrhythmia, as well as the most frequent form of arrhythmia, atrial fib...
Source: Journal of Cardiovascular Electrophysiology - October 19, 2009 Category: Cardiology Authors: JACOB TFELT-HANSEN, BO GREGERS WINKEL, MORTEN GRUNNET, THOMAS JESPERSEN Source Type: journals

Limited Response to Cardiac Resynchronization Therapy in Patients with Concomitant Right Ventricular DysfunctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Limited Response to CRT in Patients with RVD. Introduction: Patients with left ventricular dysfunction (LVD) and LV dyssynchrony may respond to cardiac resynchronization therapy (CRT). However, right ventricular dysfunction (RVD) is a predictor of decreased survival in patients with LVD, and its influence on clinical response to CRT is unknown. The purpose of this study was to examine the effect of RVD on the clinical response to CRT. Methods and Results: A retrospective cohort of consecutive patients who underwent implantation of a CRT implantable cardioverter-defibrillator (ICD) were included and deemed to have RVD based...
Source: Journal of Cardiovascular Electrophysiology - October 19, 2009 Category: Cardiology Authors: PAUL B. TABEREAUX, HARISH DOPPALAPUDI, G. NEAL KAY, H. THOMAS MCELDERRY, VANCE J. PLUMB, ANDREW E. EPSTEIN Source Type: journals

Identification of Hemodynamically Unstable Arrhythmias Using Subcutaneous PhotoplethysmographyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Subcutaneous PPG detects hemodynamically unstable simulated arrhythmias in an acute canine preparation. If successfully validated in humans, this technology may allow ICD therapy to be specifically tailored according to the hemodynamic status of the arrhythmia. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 19, 2009 Category: Cardiology Authors: ROBERT G. TURCOTT, TODD J. PAVEK Source Type: journals

Robotically Assisted Ablation Produces More Rapid and Greater Signal Attenuation Than Manual AblationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Robotically assisted ablation appears to be more effective than manual ablation at signal amplitude reduction, therefore may be expected to produce improved clinical outcomes. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 13, 2009 Category: Cardiology Authors: MICHAEL KOA-WING, PIPIN KOJODJOJO, LOUISA C. MALCOLME-LAWES, TUSHAR V. SALUKHE, NICK W.F. LINTON, AARON P. GROGAN, DALE BERGMAN, PHANG BOON LIM, ZACHARY I. WHINNETT, KAREN McCARTHY, SIEW YEN HO, MARK D. O'NEILL, NICHOLAS S. PETERS, D. WYN DAVIES, PRAPA KA Source Type: journals

Ventricular Entrainment of a Long-RP Supraventricular TachycardiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 8, 2009 Category: Cardiology Authors: MIGUEL A. ARIAS, EDUARDO CASTELLANOS, ALBERTO PUCHOL, LUIS RODRÍGUEZ-PADIAL Source Type: journals

Age-Related Increase in Atrial Fibrillation Induced by Transvenous Catheter-Based Atrial Burst Pacing: An In Vivo Rat Model of Inducible Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Transvenous catheter-based AF is significantly longer in middle-aged than in young rats and is markedly reduced by treatment with antiarrhythmic drugs. This rat model of AF is simple, reproducible, and reliable for examining pharmacologic effects on AF and studying the process of atrial remodeling. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: DONGZHU XU, NOBUYUKI MURAKOSHI, HIROSHI TADA, MIYAKO IGARASHI, YUKIO SEKIGUCHI, KAZUTAKA AONUMA Source Type: journals

Relevance of Endocavitary Structures in Ablation Procedures for Ventricular TachycardiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: During VT ablation procedures, ECS should be considered for specific mapping and targeted ablation. Once recognized, these structures can be successfully targeted for ablation without valve damage. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]10) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: OMAR ABOUEZZEDDINE, MAHMOUD SULEIMAN, TRACI BUESCHER, SURAJ KAPA, PAUL A. FRIEDMAN, ARSHAD JAHANGIR, JENNIFER A. MEARS, DOROTHY J. LADEWIG, THOMAS M. MUNGER, STEPHEN C. HAMMILL, DOUGLAS L. PACKER, SAMUEL J. ASIRVATHAM Source Type: journals

Vanoxerine, a New Drug for Terminating Atrial Fibrillation and FlutterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Vanoxerine effectively terminated induced, sustained AF and AFL in the canine SP model, and produced insignificant or minimal changes in refractoriness, conduction time, or stimulus threshold, consistent with little proarrhythmic risk. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]9) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: NAOMICHI MATSUMOTO, CELEEN M. KHRESTIAN, KYUNGMOO RYU, ANTONIO E. LACERDA, ARTHUR M. BROWN, ALBERT L. WALDO Source Type: journals

Vanoxerine: Cellular Mechanism of a New AntiarrhythmicEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Vanoxerine (1) is a potent blocker of cardiac hERG, Na and Ca channels; (2) block is strongly frequency-dependent especially for Na and Ca channels; and (3) transmural dispersion of ventricular repolarization is unaffected. The multichannel block and repolarization uniformity resemble the effects of amiodarone, the exemplar atrial fibrillation drug. Vanoxerine is a completely different chemical and has none of amiodarone's toxic effects. Vanoxerine has characteristics of a potentially effective and safe antiarrhythmic. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]10) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: ANTONIO E. LACERDA, YURI A. KURYSHEV, GAN-XIN YAN, ALBERT L. WALDO, ARTHUR M. BROWN Source Type: journals

Long-Term Outcomes of Inducible Very Fast Ventricular Tachycardia (Cycle Length 200–250 ms) in Patients With Ischemic CardiomyopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Inducible VFVT (200[ndash]250 ms) is a clinically significant arrhythmia with adverse long-term outcomes and should not be considered a nonspecific finding of PVS. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]8) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: SAURABH KUMAR, GOPAL SIVAGANGABALAN, MAN-CHUN CHOI, VICKI EIPPER, ARAVINDA THIAGALINGAM, PRAMESH KOVOOR Source Type: journals

Hybrid Therapy of Radiofrequency Catheter Ablation and Percutaneous Transvenous Mitral Commissurotomy in Patients With Atrial Fibrillation and Mitral StenosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The hybrid therapy using RFCA and a PTMC was safe and feasible, and significantly improved the AF free survival rate compared to DC following a PTMC. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: TAKESHI MACHINO, HIROSHI TADA, YUKIO SEKIGUCHI, YASUAKI TANAKA, SHIGETO NAITO, HIRO YAMASAKI, TAKANORI ARIMOTO, MIYAKO IGARASHI, KENJI KUROKI, YOSHIHIRO SEO, SHIGEYUKI WATANABE, HIROSHI HOSHIZAKI, SHIGERU OSHIMA, KOICHI TANIGUCHI, KAZUTAKA AONUMA Source Type: journals

Expression of a Common LQT1 Mutation in Five Apparently Unrelated Families in a Regional Inherited Arrhythmia ClinicEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Genetic testing in this LQTS population suggests a common KCNQ1 Leu266Pro founder effect, with the descendants clustering in our geographical region even though no common relative has been identified. The observations highlight the utility of genotypic and phenotypic correlation and a specialized clinic. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]5) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: CHRISTOPHER GRAY, LORNE J. GULA, GEORGE J. KLEIN, ALLAN C. SKANES, RAYMOND YEE, RAYMOND SY, BENJAMIN A. SALISBURY, JORGE WONG, ISHVINDER CHATTHA, RAJESH N. SUBBIAH, ANDREW D. KRAHN Source Type: journals

Mechanisms of Arrhythmia Recurrence After Video-Assisted Thoracoscopic Surgery for the Treatment of Atrial Fibrillation: Insights from Electrophysiological Mapping and AblationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: PV gaps are present, with a characteristic distribution, in the majority of patients who fail this surgical procedure, but these gaps are not responsible for the arrhythmias identified. Instead, most are macro-reentrant, isthmus-dependent arrhythmias related to clamp-associated or LAA excision-associated scars. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]8) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: XINGPENG LIU, JIANZENG DONG, HERCULES E. MAVRAKIS, BIN ZHENG, DEYONG LONG, RONGHUI YU, RIBO TANG, YING TIAN, PANOS E. VARDAS, CHANGSHENG MA Source Type: journals

Atrial Fibrillatory Wall Motion and Degree of Atrial Remodeling in Patients with Atrial Fibrillation: A Tissue Velocity Imaging StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: TVI of the atrial fibrillatory wall motion may enhance noninvasive characterization of atrial remodeling in patients with atrial fibrillation. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]8) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: CEES B. DE VOS, LAURENT PISON, RON PISTERS, ULRICH SCHOTTEN, EMILE C. CHERIEX, MARTIN H. PRINS, TAMMO DELHAAS, HARRY J.G.M. CRIJNS, ROBERT G. TIELEMAN Source Type: journals

Extreme Pulmonary Vein Tachycardia—Clue or Distraction?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: KAH-LENG HO, TRUONG-SON PHAM, LI-FERN HSU Source Type: journals

Isolated Cardiac Sarcoid in a Patient with Unexplained SyncopeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: JASON S. CHINITZ, LAWRENCE A. INRA, KENNETH M. STEIN, JONATHAN W. WEINSAFT Source Type: journals

Effect of Intravenous Adenosine on Simultaneous Dissociated Rhythms in Contralateral Superior Pulmonary VeinsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 7, 2009 Category: Cardiology Authors: PIPIN KOJODJOJO, D. WYN DAVIES, ANTHONY MASON, MARK D. O'NEILL Source Type: journals

Defibrillation Testing: The Need for a Definitive TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 5, 2009 Category: Cardiology Authors: GABOR Z. DURAY, STEFAN H. HOHNLOSER Source Type: journals

Electrophysiological Anatomy of Typical Atrial Flutter: The Posterior Boundary and Causes for Difficulty with AblationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The posterior boundary of the reentrant circuit of CVTI-AFL comprises the Eustachian ridge and CT, but in some patients may also include a second CT. Sub-Eustachian pouches on the septal CVTI are strongly associated with a prominent TV. The lateral CVTI can have prominent pectinate muscles. This comprehensive characterization of the electrophysiological anatomy of the reentrant circuit of CVTI-AFL may provide guidance and improve success during difficult ablations. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: APOOR S. GAMI, WILLIAM D. EDWARDS, NIRUSHA LACHMAN, PAUL A. FRIEDMAN, DEEPAK TALREJA, THOMAS M. MUNGER, STEPHEN C. HAMMILL, DOUGLAS L. PACKER, SAMUEL J. ASIRVATHAM Source Type: journals

Idiopathic Left Ventricular Arrhythmias Originating Adjacent to the Left Aortic Sinus of Valsalva: Electrophysiological Rationale for the Surface ElectrocardiogramEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The MDI has limited value for discriminating endocardial from epicardial VA origins in sites adjacent to the LSOV probably due to preferential conduction, intramural VA origins or myocardium in contact with the LCC. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: TAKUMI YAMADA, H. THOMAS MCELDERRY, TARO OKADA, YOSHIMASA MURAKAMI, HARISH DOPPALAPUDI, NAOKI YOSHIDA, YUKIHIKO YOSHIDA, YASUYA INDEN, TOYOAKI MUROHARA, ANDREW E. EPSTEIN, VANCE J. PLUMB, G. NEAL KAY Source Type: journals

Are MADIT II Criteria for Implantable Cardioverter Defibrillator Implantation Appropriate for Chinese Patients?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Chinese patients who satisfy MADIT-II criteria for ICD implantation are at similar risk of SCD and non-SCD as the original MADIT-II subjects. Implantation of an ICD in Chinese patients is appropriate. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]5) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: CHUNG-WAH SIU, VINCENT PONG, HEE-HWA HO, SHASHA LIU, CHU-PAK LAU, SHEUNG-WAI LI, HUNG-FAT TSE Source Type: journals

Catheter-Based Cryoablation of Postinfarction and Idiopathic Ventricular Tachycardia: Initial Experience in a Selected PopulationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In this small patient population, catheter-based cryoablation of VT was safe and effective. Future studies are needed to evaluate the effect of cryothermy in a larger group of patients, especially those with postinfarction VT. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: CARL TIMMERMANS, RANDY MANUSAMA, BECKER ALZAND, LUZ-MARIA RODRIGUEZ Source Type: journals

Magnetic Resonance Imaging-Confirmed Ablative Debulking of the Left Atrial Posterior Wall and Septum for Treatment of Persistent Atrial Fibrillation: Rationale and Initial ExperienceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Pathologic remodeling in the septal and posterior walls of the LA helps form the pathogenic substrate for AF, and these early results suggest that more aggressive treatment of these regions appears to correlate with improved ablation outcomes. Noninvasive imaging to characterize tissue changes after ablation may prove essential to stratifying recurrence risk. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: NATHAN M. SEGERSON, MARCOS DACCARETT, TROY J. BADGER, AKRAM SHABAAN, NAZEM AKOUM, ERIC N. FISH, SWATI RAO, NATHAN S. BURGON, YAW ADJEI-POKU, EUGENE KHOLMOVSKI, SATHYA VIJAYAKUMAR, EDWARD V.R. DIBELLA, ROB S. MACLEOD, NASSIR F. MARROUCHE Source Type: journals

Septal Dyskinesia and Global Left Ventricular Dysfunction in Pediatric Wolff-Parkinson-White Syndrome with Septal Accessory PathwayEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The dyskinetic segment activated by a right septal AP in WPW syndrome may lead to ventricular dilation and dysfunction. RFA produced mechanical resynchronization, reverse remodeling, and improvements in LV function. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: BO SANG KWON, EUN JUNG BAE, GI BEOM KIM, CHUNG IL NOH, JUNG YUN CHOI, YONG SOO YUN Source Type: journals

Chronic Augmentation of the Parasympathetic Tone to the Atrioventricular Node: A Nonthoracotomy Neurostimulation Technique for Ventricular Rate Control During Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Long-Term Cardiac Neurostimulation. Introduction: The right inferior ganglionated plexus (RIGP) selectively innervates the atrioventricular node. Temporary electrical stimulation of this plexus reduces the ventricular rate during atrial fibrillation (AF). We sought to assess the feasibility of chronic parasympathetic stimulation for ventricular rate control during AF with a nonthoracotomy intracardiac neurostimulation approach. Methods and Results: In 9 mongrel dogs, the small endocardial area inside the right atrium, which overlies the RIGP, was identified by 20 Hz stimulation over a guiding catheter with integrated elect...
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: KARL MISCHKE, MARKUS ZARSE, MICHAEL SCHMID, CHRISTOPHER GEMEIN, NIMA HATAM, JAN SPILLNER, GUIDO DOHMEN, OBAIDA RANA, EROL SAYGILI, CHRISTIAN KNACKSTEDT, JOACHIM WEIS, DAINIUS PAUZA, STEFANO BIANCHI, PATRICK SCHAUERTE Source Type: journals

Electrocardiographic Findings, Device Therapies, and Comorbidities in Octogenarian Implantable Defibrillator RecipientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Our study is the first to evaluate in detail the therapies received by octogenarians after ICD placement. The higher incidence of SB and LBBB might influence the number of pacing sites in octogenarian patients. Very elderly patients have similar rates of arrhythmic episodes and development of severe comorbidities as septuagenarians, and they should not be denied ICD implantation based solely on age. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: JAMES D. DANIELS, JUSTIN SAUNDERS, SUNTHOSH PARVATHANENI, AMANDA BYRD, JOSE A. JOGLAR, OWEN OBEL Source Type: journals

Image-Integration of Intraprocedural Rotational Angiography-Based 3D Reconstructions of Left Atrium and Pulmonary Veins into Electroanatomical Mapping: Accuracy of a Novel Modality in Atrial Fibrillation AblationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Intraprocedural registration of LA and PV anatomy by contrast enhanced rotational angiography was feasible and accurate. There were no differences between patients with paroxysmal or persistent AF. Therefore, integration of rotational angiography-based reconstructions into 3D EAM systems might be helpful to guide catheter ablation for AF. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: GEORG NÖLKER, STEFAN ASBACH, KLAUS J. GUTLEBEN, HARALD RITTGER, GUIDO RITSCHER, JOHANNES BRACHMANN, ANIL. M. SINHA Source Type: journals

Canadian Registry of ICD Implant Testing Procedures (CREDIT): Current Practice, Risks, and Costs of Intraoperative Defibrillation TestingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: DT was not performed in a third of ICD implants, usually due to a perceived lack of need or relative contraindication. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: JEFF S. HEALEY, PAUL DORIAN, L. BRENT MITCHELL, MARIO TALAJIC, FRANCOIS PHILIPPON, CHRIS SIMPSON, RAYMOND YEE, CARLOS A. MORILLO, ANDRE LAMY, MAGDY BASTA, DAVID H. BIRNIE, XIAOYIN WANG, GIRISH M. NAIR, EUGENE CRYSTAL, CHARLES R. KERR, STUART J. CONNOLLY Source Type: journals

Characteristics of Complex Fractionated Electrograms in Nonpulmonary Vein Ectopy Initiating Atrial Fibrillation/Atrial TachycardiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The sites of the origin of the non-PV ectopies were at the same location as those of the atrial continuous CFAEs. Those non-PV foci were able to initiate and sustain AF/AT. By limited ablation targeting all atrial continuous CFAEs, the AF could be effectively eliminated. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]8) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - October 4, 2009 Category: Cardiology Authors: LI-WEI LO, YENN-JIANG LIN, HSUAN-MING TSAO, SHIH-LIN CHANG, YU-FENG HU, WEN-CHIN TSAI, DA-CHUN TUAN, CHIEN-JUNG CHANG, PI-CHANG LEE, CHING-TAI TAI, WEI-HUA TANG, KAZUYOSHI SUENARI, SHIH-YU HUANG, SATOSHI HIGA, SHIH-ANN CHEN Source Type: journals