Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy
ae & Neil J Spratt (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Lucy A MurthaDamian D McLeodDebbie PepperallSarah K McCannDaniel J BeardAmelia J TomkinsWilliam M HolmesChristopher McCabeI Mhairi MacraeNeil J Spratt Source Type: research

Comparative assessment of parametric neuroreceptor mapping approaches based on the simplified reference tissue model using [11C]ABP688 PET
Comparative assessment of parametric neuroreceptor mapping approaches based on the simplified reference tissue model using [11C]ABP688 PET Journal of Cerebral Blood Flow & Metabolism 35, 2098 (December 2015). doi:10.1038/jcbfm.2015.190 Authors: Seongho Seo, Su J Kim, Yu K Kim, Jee-Young Lee, Jae M Jeong, Dong S Lee & Jae S Lee (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Seongho SeoSu J KimYu K KimJee-Young LeeJae M JeongDong S LeeJae S Lee Tags: neuroreceptor imaging parametric image simplified reference tissue model total least squares tracer kinetic modeling Source Type: research

The indirect NMDAR antagonist acamprosate induces postischemic neurologic recovery associated with sustained neuroprotection and neuroregeneration
& Dirk M Hermann (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Thorsten R DoeppnerJens R PehlkeBritta KaltwasserJana SchlechterErtugrul KilicMathias BährDirk M Hermann Tags: animal models basic science brain ischemia excitotoxicity focal ischemia neuroregeneration Source Type: research

Knockout of silent information regulator 2 (SIRT2) preserves neurological function after experimental stroke in mice
mp; George Trendelenburg (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Lea KreyFred LühderKathrin KuschBozena Czech-ZechmeisterBirte KönneckeTiago Fleming OuteiroGeorge Trendelenburg Tags: cerebral ischemia inflammasome inflammation sirtuin stroke Source Type: research

MR derived volumetric flow rate waveforms of internal carotid artery in patients treated for unruptured intracranial aneurysms by flow diversion technique
& Guy Courbebaisse (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Omer F EkerKarim Zouaoui BoudjeltiaRicardo A Corredor JerezEmmanuelle Le BarsMathieu SanchezAlain BonaféVincent CostalatGuy Courbebaisse Tags: carotid artery hemodynamics interventional neuroradiology intracranial aneurysm magnetic resonance Source Type: research

Assessing cerebral glucose metabolism in patients with idiopathic rapid eye movement sleep behavior disorder
ong Ma & Jian Wang (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Jingjie GePing WuShichun PengHuan YuHuiwei ZhangYihui GuanDavid EidelbergChuantao ZuoYilong MaJian Wang Tags: 18F-fluorodeoxyglucose Parkinson’s disease positron emission tomography rapid eye movement sleep behavior disorder statistic parametric mapping analysis Source Type: research

Non-additive effects of delayed connexin hemichannel blockade and hypothermia after cerebral ischemia in near-term fetal sheep
p; Alistair J Gunn (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Joanne O DavidsonAlexandra L RoutGuido WassinkCaroline A YuillFrank G ZhangColin R GreenLaura BennetAlistair J Gunn Tags: cerebral hypothermia cerebral ischemia connexin hemichannel fetal sheep neuroprotection Source Type: research

STAT-dependent upregulation of 12/15-lipoxygenase contributes to neuronal injury after stroke
STAT-dependent upregulation of 12/15-lipoxygenase contributes to neuronal injury after stroke Journal of Cerebral Blood Flow & Metabolism 35, 2043 (December 2015). doi:10.1038/jcbfm.2015.169 Authors: Joo Eun Jung, Hulya Karatas, Yu Liu, Ayfer Yalcin, Joan Montaner, Eng H Lo & Klaus van Leyen (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Joo Eun JungHulya KaratasYu LiuAyfer YalcinJoan MontanerEng H LoKlaus van Leyen Tags: ischemia lipoxygenase neuron STAT transcription factor Source Type: research

The cumulative influence of hyperoxia and hypercapnia on blood oxygenation and R2*
The cumulative influence of hyperoxia and hypercapnia on blood oxygenation and R2* Journal of Cerebral Blood Flow & Metabolism 35, 2032 (December 2015). doi:10.1038/jcbfm.2015.168 Authors: Carlos C Faraco, Megan K Strother, Jeroen CW Siero, Daniel F Arteaga, Allison O Scott, Lori C Jordan & Manus J Donahue (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Carlos C FaracoMegan K StrotherJeroen CW SieroDaniel F ArteagaAllison O ScottLori C JordanManus J Donahue Tags: BOLD cerebrovascular reactivity hypercapnia hyperoxia R2* Source Type: research

Recombinant tissue-type plasminogen activator transiently enhances blood–brain barrier permeability during cerebral ischemia through vascular endothelial growth factor-mediated endothelial endocytosis in mice
Recombinant tissue-type plasminogen activator transiently enhances blood–brain barrier permeability during cerebral ischemia through vascular endothelial growth factor-mediated endothelial endocytosis in mice Journal of Cerebral Blood Flow & Metabolism 35, 2021 (December 2015). doi:10.1038/jcbfm.2015.167 Authors: Yasuhiro Suzuki, Nobuo Nagai, Kasumi Yamakawa, Yoshinori Muranaka, Kazuya Hokamura & Kazuo Umemura (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Yasuhiro SuzukiNobuo NagaiKasumi YamakawaYoshinori MuranakaKazuya HokamuraKazuo Umemura Tags: brain ischemia endothelial endocytosis tissue-type plasminogen activator vascular endothelial growth factor vascular permeability Source Type: research

S100B inhibition reduces behavioral and pathologic changes in experimental traumatic brain injury
mp; Alan I Faden (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Shruti V KabadiBogdan A StoicaDanna B ZimmerLauriaselle AfanadorKara B DuffyDavid J LoaneAlan I Faden Tags: AGER behavior (rodent) brain trauma microglia neurodegeneration neuroprotection S100B Source Type: research

Measurement of Bmax and Kd with the glycine transporter 1 radiotracer 18F-MK6577 using a novel multi-infusion paradigm
mp; Richard E Carson (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Yan XiaMing-Qiang ZhengDaniel HoldenShu-fei LinMichael KapinosJim RopchanJean-Dominique GallezotYiyun HuangRichard E Carson Tags: 18F-MK6577 GlyT1 in vivo Kd multi-infusion parametric Bmax image Source Type: research

Decreased microvascular cerebral blood flow assessed by diffuse correlation spectroscopy after repetitive concussions in mice
& Michael J Whalen (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Erin M BuckleyBenjamin F MillerJulianne M GolinskiHoma SadeghianLauren M McAllisterMark VangelCenk AyataWilliam P Meehan IIIMaria Angela FranceschiniMichael J Whalen Tags: animal models brain trauma optical imaging Source Type: research

Mechanism of brain targeting by dexibuprofen prodrugs modified with ethanolamine-related structures
amp; Zhirong Zhang (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Yanping LiYangyang ZhouJiayu JiangXinyi WangYao FuTao GongXun SunZhirong Zhang Tags: brain-targeting prodrugs dexibuprofen ethanolamine-related structures mechanism pyrilamine-sensitive H /OC antiporter Source Type: research

MicroRNA-29b is a therapeutic target in cerebral ischemia associated with aquaporin 4
yang & Guo-Yuan Yang (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2015 Category: Neuroscience Authors: Yang WangJun HuangYuanyuan MaGuanghui TangYanqun LiuXiaoyan ChenZhijun ZhangLili ZengYongting WangYi-Bing OuyangGuo-Yuan Yang Tags: aquaporin-4 human ischemia microRNA-29b stroke Source Type: research