Altered expression of circular RNAs in human placental chorionic plate ‐derived mesenchymal stem cells pretreated with hypoxia
ConclusionsThe results indicate that the altered expression of specific circRNAs in MSCs is associated with hypoxic preconditioning. This finding provides further exploration of underlying mechanisms of the characteristic changes of MSCs with hypoxic preconditioning. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 28, 2018 Category: Laboratory Medicine Authors: Xunsha Sun, Yulin Jin, Qihua Liang, Jie Tang, Jinsong Chen, Qiuxia Yu, Fatao Li, Yan Li, Jieying Wu, Shaoqing Wu Tags: RESEARCH ARTICLE Source Type: research

Use of the Sysmex XT ‐4000i hematology analyzer in the differentiation of cerebrospinal fluid cells in children
ConclusionWe conclude that automated method cannot fully replace the previously used manual method and some of the dubious cases, such as samples with low pleocytosis rates or abnormal cells indicated by the analyzer, will still require microscopic examination. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 28, 2018 Category: Laboratory Medicine Authors: Beata Zelazowska ‐Rutkowska, Janusz Zak, Malgorzata Wojtkowska, Justyna Zaworonek, Bogdan Cylwik Tags: RESEARCH ARTICLE Source Type: research

Importance of sample volume to the measurement and interpretation of plasma osmolality
ConclusionsThese results demonstrate that Posm measured by freezing point depression will be ~7  mmol/kg higher when using 20 μL vs 250 μL sample volumes. Approximately half of this effect may be due to plasma proteins. Posm sample volume should be carefully considered when calculating the osmole gap or assessing hydration status. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 25, 2018 Category: Laboratory Medicine Authors: Kurt J. Sollanek, Robert W. Kenefick, Samuel N. Cheuvront Tags: RESEARCH ARTICLE Source Type: research

Letter to the Editor Regarding Article, “High mobility group box 1 as a biomarker in critically ill patients”
Journal of Clinical Laboratory Analysis, EarlyView. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 25, 2018 Category: Laboratory Medicine Authors: Zhi ‐Qing Chen, Feng Chen, Lang Li Tags: LETTER TO THE EDITOR Source Type: research

Response to the "Letter to the editor regarding article, 'High ‐mobility group box 1 as a biomarker in critically ill patients'.”
Journal of Clinical Laboratory Analysis, EarlyView. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 25, 2018 Category: Laboratory Medicine Authors: Alexander Koch, Frank Tacke Tags: LETTER TO THE EDITOR Source Type: research

Combined testing for herpes simplex virus and Mycobacterium tuberculosis DNA in cerebrospinal fluid of patients with aseptic meningitis in Burkina Faso, West Africa
ConclusionUsing an in ‐house real‐time PCR assay, we showed that both HSV and MTB are etiologic pathogens contributing to aseptic meningitis in Burkina Faso. This molecular test may have clinical utility for early diagnosis for those treatable CNS infections. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 25, 2018 Category: Laboratory Medicine Authors: Sylvie Zida, Pratt Kolia ‐Diafouka, Dramane Kania, Albert Sotto, Vincent Foulongne, Karine Bolloré, Soumeya Ouangraoua, Nicolas Méda, Séverine Carrère‐Kremer, Philippe Van de Perre, Edouard Tuaillon Tags: RESEARCH ARTICLE Source Type: research

Circulating CEA ‐dNLR score predicts clinical outcome of metastatic gallbladder cancer patient
ConclusionOur findings implied that pretreatment CEA ‐dNLR score was superior to the other biomarkers to predict OS of mGBC patients, and it was an independent prognostic factor for the disease. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: Jing ‐Hui Du, Jun Lu Tags: RESEARCH ARTICLE Source Type: research

The relationship between platelet indices and ABO blood groups in healthy adults
ConclusionsBecause MPV and PDW are used as markers of CVDs, individuals with O and A blood groups in this study may be considered to have a lower risk of CVDs than AB and B blood group subjects. However, prospective cohort studies involving a greater number of volunteers are needed to elucidate these relationships. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: Hakim Celik, Ufuk Duzenli, Mehmet Aslan, Ibrahim Halil Altiparmak, Adnan Kirmit, Erdal Kara, Ali Ziya Karakilcik Tags: RESEARCH ARTICLE Source Type: research

A low cost and input tailing method of quality control on multiple annealing, and looping ‐based amplification cycles‐based whole‐genome amplification products
ConclusionsOur tailing method can provide a new WGA quality test to evaluate the WGA efficiency with 100% accuracy (42/42). Compared with qPCR panel, our tailing method needs lower input, cheaper cost, shorter manual time, a clear filtering cut off, and extendable high throughput as well as the same sensitivity. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: Changyue Chen, Jing Li, JueFeng Wan, Yuan Lu, Zhen Zhang, ZengHui Xu Tags: RESEARCH ARTICLE Source Type: research

Prevalence of food ‐allergen and aeroallergen sensitization among people in Sichuan, Western China: An 8‐year observational study
ConclusionThe most common allergens presented in Sichuan were observed to be mites, crab, sea ‐fish, and house dust. There was an observable difference in sensitivity to five allergens between males and females. Additionally, aeroallergens appeared to have a greater immunogenic effect in younger populations while the elderly presented with increased sensitization to specific allergens, sug gesting that specific allergens' immunogenicity was age‐dependent. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: Zhuochun Huang, Weihua Feng, Wei Wei, Bin Yang, Lanlan Wang Tags: RESEARCH ARTICLE Source Type: research

Direct detection from clinical sputum samples to differentiate live and dead Mycobacterium Tuberculosis
Conclusionswe develop an acceptable method to directly identify the live bacteria from sputum samples. Our data demonstrate that the dark incubation plays a crucial role in the efficacy of PMA treatment for MTB. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: Jie Lu, Huiwen Zheng, Ping Chu, Shujing Han, Hui Yang, Zhongdong Wang, Jin Shi, Zuosen Yang Tags: RESEARCH ARTICLE Source Type: research

Current status of treatment of type 2 diabetes mellitus in Ningbo, China
ConclusionNingbo City T2DM status is not optimistic, and there is a big gap with the indicators. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: Tianmeng Yang, Rongjiong Zheng, Qingmei Chen, Yushan Mao, The Ningbo Clinical Research Group of Diabetes Tags: RESEARCH ARTICLE Source Type: research

Preliminary study of the relationship between promoter methylation of the ANGPTL2 gene and coronary heart disease
ConclusionsThe present work provides evidence to support an association betweenANGPTL2 promoter DNA methylation status and the risk profile of CHD in females. Our data indicated that in females, promoter DNA hypomethylation of theANGPTL2 gene is associated with an increased risk of CHD. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: Jianqing Zhou, Li Chen, Xi Yang, Xiaoyan Huang, Zicheng Wang, Ping Peng, Jiangfang Lian Tags: RESEARCH ARTICLE Source Type: research

Hsa_circ_0000467 promotes cancer progression and serves as a diagnostic and prognostic biomarker for gastric cancer
ConclusionHsa_circ_0000467 can act as a novel noninvasive biomarker for the diagnosis and prognosis of GC and may be a potential therapeutic target for GC. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: Jun Lu, Peng ‐yang Zhang, Jian‐wei Xie, Jia‐bin Wang, Jian‐xian Lin, Qi‐yue Chen, Long‐long Cao, Chang‐ming Huang, Ping Li, Chao‐hui Zheng Tags: RESEARCH ARTICLE Source Type: research

Association of VDR ‐FokI and VDBP‐Thr420Lys polymorphisms with cervical spondylotic myelopathy: A case‐control study in the population of China
ConclusionBinary logistic regression analysis confirmed thatVDR‐FokI polymorphism and the time to bend over desk working were risk factors of CSM. Our results indicate thatVDR‐FokI polymorphism may be closely associated with the risk of CSM. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - November 21, 2018 Category: Laboratory Medicine Authors: De ‐Wei Song, Yu‐Dong Wu, Dong‐Dong Tian Tags: RESEARCH ARTICLE Source Type: research