Investigating In situ Expression of Neurotrophic Factors and Partner Proteins in Irreversible Pulpitis
In situ assessments of neurotrophic factors and their associated molecular partners have not been explored to date particularly in humans. The present investigation aims to explore the expressional dysregulation of neurotrophic factors (NGF, BDNF and NT4/5), their receptors (TrkA and TrkB) and their modulators (USP36 and Nedd4-2) directly in irreversibly inflamed human pulp tissues. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 1, 2023 Category: Dentistry Authors: Fatima Israr, Syed Masood ul Hasan, Mushtaq Hussain, Fazal ur Rehman Qazi, Arshad Hasan Tags: Basic Research-Biology Source Type: research
Prevalence of and factors associated with vertical root fracture in a Japanese population: an observational study on teeth with isolated periodontal probing depth
This study examined teeth with an isolated periodontal probing depth (PD) as an indicator of VRF. The primary aim of this study was to investigate the prevalence of vertical root fracture (VRF) and non-VRF among teeth with an isolated probing depth (PD) ≥ 5 mm, the secondary aim was to assess factors associated with VRF by comparing the teeth with and without VRF in the Japanese population. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 1, 2023 Category: Dentistry Authors: Kwangsoon Lee, Manjeet Ahlowalia, Ruth Perez Alfayate, Shanon Patel, Federico Foschi Tags: Clinical Research Source Type: research
Erratum
for, “The Effect of Mineral Trioxide Aggregate Obturation Levels on the Outcome of Endodontic Retreatment: An Observational Study” [J Endodon 49 (2023) 664-674] (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 31, 2023 Category: Dentistry Tags: Erratum Source Type: research
Diagnosis of Odontogenic Maxillary Sinusitis by Cone-beam Computed Tomography: A Critical Review
This review aims to provide an up-to-date overview of the current applications of cone-beam computed tomography (CBCT) and other imaging modalities in diagnosing odontogenic maxillary sinusitis (OMS). Furthermore, the clinical operation procedures of radiography modalities in OMS diagnosis were summarized, with the goal of assisting clinicians in improving OMS diagnostic accuracy in clinical practice. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 31, 2023 Category: Dentistry Authors: Jinglan Zhang, Liu Liu, Lei Yang, Jing Wang, Xuelian Tan, Dingming Huang Tags: Review Article Source Type: research
Biological Function and Potential Applications of Garcinol in Human Dental Pulp Stem Cells
In this study, the inhibitory effect of garcinol on the osteogenic differentiation of human dental pulp stem cells (hDPSCs) was evaluated using three-dimensional culture under in vitro and in vivo conditions. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 30, 2023 Category: Dentistry Authors: Sunmi Jang, Uk-Seong Kim, Sukjoon Lee, Euiseong Kim, Han-Sung Jung, Su-Jung Shin, Sumi Kang, Sunil Kim Tags: Regenerative Endodontics Source Type: research
A Survey on Cone-beam Computed Tomography Usage Among Endodontists in the United States
The aim of the study was to investigate the accessibility and frequency of cone-beam computed tomography usage (CBCT) and to assess the economic and logistical factors involved with its usage among active American Association of Endodontists (AAE) members, utilizing a web-based survey. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 30, 2023 Category: Dentistry Authors: Christie Duong, Qiang Zhu, Robert H. Aseltine, Chia-Ling Kuo, Lucas da Cunha Godoy, Blythe Kaufman Tags: Basic Research-Technology Source Type: research
Long-Term Clinical and Radiographic Observation of Previously Regenerated Treated Incisors Subjected to Orthodontic Movement. A Case Series.
With an increasing number of anterior traumatized teeth treated with REPs nowadays, orthodontic movement of such teeth is expected to become a common scenario in everyday clinical practice. However, little is known about the clinical implications and the response capacity of regenerated tissues to orthodontic forces. The aim of this clinical article was to report on four cases of REP-treated immature anterior permanent teeth subjected to orthodontic forces, and to describe the long-term response of the regenerated apical and intracanal tissues. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 30, 2023 Category: Dentistry Authors: Spyridon Stefopoulos, Kostas Kodonas, Giorgos N. Tzanetakis Tags: Regenerative Endodontics Source Type: research
Association of Apical Periodontitis with different stages of Chronic Kidney Disease measured by Glomerular filtration rate and Systemic markers: An Observational Study
The aim of this study was to assess the prevalence and severity of apical periodontitis (AP) in subjects with different stages of chronic kidney disease (CKD) and its association with systemic markers. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 26, 2023 Category: Dentistry Authors: Jyoti Lamba, Shweta Mittal, Sanjay Tewari, Deepak Jain, Shikha Tewari, Jigyasa Duhan, Pankaj Sangwan, Vinay Kumar Tags: Clinical Research Source Type: research
Symptomatic Irreversible Pulpitis induces increased levels of human NLRP3 in gingival crevicular fluid compared to Saliva- a case control observational study
The goal of this case-control observational study was to compare the levels of the human nucleotide-binding domain, leucine-rich repeat, and pyrin domain-containing-3 (NLRP3) protein in the saliva and gingival crevicular fluid of patients with symptomatic irreversible pulpitis (SIP) and healthy controls. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 25, 2023 Category: Dentistry Authors: Dax Abraham, Arundeep Singh, Anjana Goyal Tags: Clinical Research Source Type: research
Clinical Outcome and Predictors of Endodontic Microsurgery Using Cone-beam Computed Tomography: A Retrospective Cohort Study
The aim of this retrospective cohort study was to evaluate the clinical outcomes and identify the prognostic factors of endodontic microsurgery based on cone-beam computed tomographic (CBCT) scans. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 24, 2023 Category: Dentistry Authors: Ming-Ming Zhang, Gao-Feng Fang, Zu-Hua Wang, Yu-Hong Liang Tags: Clinical Research Source Type: research
Zoledronic acid modulates cytokine expression and mitigates bone loss during the development of induced apical periodontitis in a mice model
This study aimed to assess the impact of zoledronic acid on the progression of induced apical periodontitis and expression of cytokines IL-1 β, IL-10, IL-6 and TNF-α, in a mice model. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 24, 2023 Category: Dentistry Authors: Caroline Andrade Maia, Hebertt Gonzaga dos Santos Chaves, Francine Benetti, ustavo Batista de Menezes, Ma ísa Mota Antunes, Karem Paula Pinto, Emmanuel João Nogueira Leal da Silva, Antônio Paulino Ribeiro Sobrinho, Warley Luciano Fonseca Tavares Tags: Basic Research-Biology Source Type: research
Clinical Outcome and Predictors of Endodontic Microsurgery Using Cone Beam Computed Tomography: A Retrospective Cohort Study
The aim of this retrospective cohort study was to evaluate the clinical outcomes and identify the prognostic factors of endodontic microsurgery based on cone-beam computed tomographic (CBCT) scans. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 24, 2023 Category: Dentistry Authors: Ming-Ming Zhang, Gao-Feng Fang, Zu-Hua Wang, Yu-Hong Liang Tags: Clinical Research Source Type: research
Neutrophil Extracellular Traps aggravate apical periodontitis by stimulating osteoclast formation
Neutrophil Extracellular Traps (NETs) have been described as structures composed of DNA and proteins, such as elastase and myeloperoxidase, which are able to kill bacteria extracellularly. The aim of the present study was to evaluate the role of NETs in bone resorption observed in pulp infection-induced apical periodontitis in mice. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 22, 2023 Category: Dentistry Authors: Jo ão Luiz Guilherme Neto, Lucas Gabriel Rodrigues Venturini, Ayda Henriques Schneider, Thaise Mayumi Taira, Letícia Fernanda Duffles Rodrigues, Flávio Protásio Veras, Sicília Rezende Oliveira, Tarcília Aparecida da Silva, Fernando Queiroz Cunha, Sa Tags: Basic Research-Biology Source Type: research
Prevalence of Fusobacterium Species in Endodontic Infections detected with molecular methods: Systematic Review and Meta-analysis
Endodontic infections are polymicrobial; however, investigating the role of bacterial species is critical as they may influence pathogenesis, development of symptoms, or persistence of disease. This systematic review aimed to determine the prevalence of Fusobacterium species and its association with different types of endodontic infections. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 21, 2023 Category: Dentistry Authors: Hatem A. Alhadainy, Amany H. Abdel-karim, Ashraf F. Fouad Tags: Review Article Source Type: research
Comparison of dentin microstructure and its correlation to the direction of fracture line in mandibular molars of young and older individuals - in vitro study.
The aim of the study was to assess the presence and extent of sclerotic dentin and to study its impact on the direction of fracture lines in extracted mandibular first molars of young (20 to 44 years) and older age groups (45 and above). (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 21, 2023 Category: Dentistry Authors: Vinutha Jaganathan, Rega Kumar, Ruchika R. Nawal, Sangeeta Talwar Tags: Basic Research-Biology Source Type: research
