Process-Related Factors are as Important as Outcomes for Patients Undergoing Nonsurgical Root Canal Treatment, Nonsurgical Root Canal Retreatment, and Endodontic Microsurgery
There is considerable variation in the reporting of treatment outcomes in endodontics. Patient-centered outcomes are often inadequately reported in endodontic outcome studies. This paper explores patients ’ expectations and reported outcomes in nonsurgical root canal treatment (NS-RCT), nonsurgical root canal retreatment (NS-ReTx), and endodontic microsurgery (EMS). (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 21, 2023 Category: Dentistry Authors: Maryam Zanjir, Amir Azarpazhooh, Yasaman Hosseini, Elaine Cardoso, Carilynne Yarascavitch, Prakesh S. Shah, Joanna Sale Tags: Clinical Research Source Type: research

Enhancement of Antimicrobial Effect of Endodontic Sealers Using Nanoparticles: A Systematic Review
The elimination of biofilms during root canal therapy continues to pose a challenge due to complex anatomies and un-instrumented portions of the root canal system. The incorporation of nanoparticles in endodontic sealers is an area of interest for potentially enhancing antimicrobial activity and improving treatment outcomes. This systematic review evaluated the antimicrobial effects of various nanoparticles in endodontic sealers. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 20, 2023 Category: Dentistry Authors: Kisa Iqbal, Rami Alhomrany, Louis H. Berman, Sami Chogle Tags: Review Article Source Type: research

Influence of a Metal Artifact Reduction Filter on The Diagnostic Accuracy of Complete and Incomplete Vertical Root Fractures
This study aimed to assess the influence of the e-vol DX BAR filter on the diagnostic accuracy of complete and incomplete vertical root fractures (VRFs). (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 19, 2023 Category: Dentistry Authors: Luiz Carlos de Lima Dias-Junior, Marcio Correa, Olavo Cesar Lyra Porto, Carlos Estrela, Cleonice da Silveira Teixeira, Lucas da Fonseca Roberti Garcia, Eduardo Antunes Bortoluzzi Tags: Basic Research-Technology Source Type: research

Successful root canal treatment of an atypical mandibular canine with a boomerang-shaped root and canal system with a large periapical lesion —A case report with 9-year follow-up
This report describes an atypical mandibular canine with a single boomerang-shaped root and root canal system with a large periapical lesion managed by root canal treatment. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 17, 2023 Category: Dentistry Authors: Jos é Antonio González Sánchez, Montserrat Munill Ferrer, Nandini Suresh, Venkateshbabu Nagendrababu, Paul M.H. Dummer, Marc Garcia-Font, Francesc Abella Sans Tags: Case Report/Clinical Techniques Source Type: research

Management of apico-marginal defects with endodontic microsurgery and guided tissue regeneration: a report of thirteen cases
The loss of periodontal tissue support and vertical buccal bone loss in apico-marginal defects can often be mistaken for features indicative of vertical root fractures and this study reports thirteen cases with persistent symptomatic apical periodontitis, apico-marginal defects, and large periapical lesions that were managed with endodontic microsurgery in conjunction with bone grafts and barrier placements with a follow-up period of up to 9 years. At the recall sessions, all cases were asymptomatic with radiographical success with only two cases exhibiting residual apical radiolucency, but with evident reduction in the le...
Source: Journal of Endodontics - July 17, 2023 Category: Dentistry Authors: Abayomi O. Baruwa, Jorge N.R. Martins, Mariana D. Pires, Beatriz Pereira, Pedro May Cruz, Ant ónio Ginjeira Tags: Case Report/Clinical Techniques Source Type: research

Metformin reduces bone resorption in apical periodontitis through regulation of osteoblast and osteoclast differentiation
We have previously demonstrated that auxiliary metformin therapy promotes healing of apical periodontitis. Here we aimed to investigate the effects of metformin on osteoblast differentiation and osteoclast formation in cultured cells and rat apical periodontitis. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 13, 2023 Category: Dentistry Authors: Chi-Yuan Hong, Sze-Kwan Lin, Han-Wei Wang, Chia-Tung Shun, Cheng-Ning Yang, Eddie Hsiang-Hua Lai, Shih-Jung Cheng, Mu-Hsiung Chen, Hsiang Yang, Hung-Ying Lin, Fang-Yu Wu, Sang-Heng Kok Tags: Basic Research-Biology Source Type: research

Augmented Reality and 3-dimensional Dynamic Navigation System Integration for Osteotomy and Root-end Resection
This study investigates the feasibility of integrating an augmented reality head-mounted device (AR) into a 3-dimensional dynamic navigation system (3D-DNS) for osteotomy and root-end resection (RER). It compares the accuracy and efficiency of AR + 3D-DNS to 3D-DNS for osteotomy and RER. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 13, 2023 Category: Dentistry Authors: Frederico C. Martinho, Ina L. Griffin, Jeffery B. Price, Patricia A. Tordik Tags: Basic Research-Technology Source Type: research

Flare-ups After Nonsurgical Retreatments: Incidence, Associated Factors, and Prediction
The aims of this study were to determine the incidence, associated factors, and predictability of flare-ups after nonsurgical retreatments (NSRetx). (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 12, 2023 Category: Dentistry Authors: Ali Nosrat, Michael Valancius, Sahar Mehrzad, Omid Dianat, Prashant Verma, Anita Aminoshariae, Ashraf F. Fouad Tags: Clinical Research Source Type: research

Flare-ups after Non-surgical Retreatments: Incidence, Associated Factors, and Prediction
The aims of this study were to determine the incidence, associated factors, and predictability of flare-ups after non-surgical retreatments (NSRetx). (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 12, 2023 Category: Dentistry Authors: Ali Nosrat, Michael Valancius, Sahar Mehrzad, Omid Dianat, Prashant Verma, Anita Aminoshariae, Ashraf F. Fouad Tags: Clinical Research Source Type: research

Could low-dose cone-beam ct be used for endodontic intraoperative diagnosis?
Cone-beam CT (CBCT) allows three-dimensional evaluation and has high diagnostic accuracy of endodontic conditions. Considering that the most indicated protocol for endodontics should have smaller field-of-view and higher spatial resolution, a higher radiation dose may be associated. Thus, this study evaluated the accuracy of an optimized CBCT protocol for the detection of intraoperative endodontic complications. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 12, 2023 Category: Dentistry Authors: Jo ão Pedro de Lima, Jardel Francisco Mazzi-Chaves, Manoel Damião de Sousa-Neto, Amanda Pelegrin Candemil Tags: Basic Research-Technology Source Type: research

Outcome of Partial Pulpotomy in Immature Permanent Teeth with Symptomatic Irreversible Pulpitis: A Prospective Case Series Assessment
The aim of this prospective case series was to assess the clinical and radiographic outcome of partial pulpotomy in caries-exposed symptomatic, vital, immature, permanent molars. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 11, 2023 Category: Dentistry Authors: Giorgos N. Tzanetakis, Stela Papanakou, Despina Koletsi, Maria Georgopoulou Tags: Regenerative Endodontics Source Type: research

Outcome of Partial Pulpotomy in Immature Permanent Teeth with Symptomatic Irreversible Pulpitis. A Prospective Case Series Assessment
The aim of this prospective case series was to assess the clinical and radiographic outcome of partial pulpotomy in caries-exposed symptomatic, vital, immature, permanent molars. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 11, 2023 Category: Dentistry Authors: Giorgos N. Tzanetakis, Stela Papanakou, Despina Koletsi, Maria Georgopoulou Tags: Regenerative Endodontics Source Type: research

Effects of Diabetes on Elemental levels and Nanostructure of Root Canal Dentin
This study evaluated the effects of diabetes mellitus (DM) on the nanostructure of root canal dentin using high-resolution transmission electron microscopy (HRTEM) and inductively coupled plasma mass spectrometry (ICP-MS). (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 8, 2023 Category: Dentistry Authors: Mohammad Ali Saghiri, Julia Vakhnovetsky, Elham Samadi, Salvatore Napoli, Fatereh Samadi, Michael Conte, Steven M. Morgano Tags: Basic Research-Technology Source Type: research

Reparative Dentin Formation Following Dental Pulp Capping is Mediated by TNFR1 In  Vivo
Tumor necrosis factor (TNF)- α is a pro-inflammatory cytokine that promotes biomineralization in vitro in dental pulp cells. However, the role of TNF-α-TNF receptor 1 (TNFR1) signaling in reparative dentin formation and related inflammatory pathways is not known. Therefore, the aim of this study was to evaluate the role of t he TNF-α-TNFR1 axis in dental pulp repair following pulp capping in vivo. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 7, 2023 Category: Dentistry Authors: Luciano Aparecido de Almeida-Junior, Lisa Danielly Curcino Araujo, Giuliana Campos Chaves Lamarque, Maya Fernanda Manfrin Arnez, Yvonne Lorraine Kapila, L éa Assed Bezerra da Silva, Francisco Wanderley Garcia de Paula-Silva Tags: Basic Research Source Type: research

Evaluation of serum levels of cytokines in acute apical abscess: a longitudinal observational study
This study aimed to investigate the changes in systemic cytokine levels in patients with AAA and trismus onset, post-antibiotic treatment, and post-root canal disinfection. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 7, 2023 Category: Dentistry Authors: Claudia Azucena Palafox-S ánchez, Alvaro Cruz, Diana Celeste Salazar-Camarena, Luis Gerardo Gascón, Luciano Tavares Angelo Cintra, José Francisco Muñoz-Valle, Samuel García-Arellano, Carlos Estrela, Paula Annahi Menchaca-Tapia Tags: Clinical Research Source Type: research