Comparison of Three Different Stents for EUS ‐guided Drainage of Pancreatic Fluid Collection: A Large Retrospective Study
ConclusionsThere are no significant differences in the clinical outcomes of PFC patients treated with PS, FCSEMS or LAMS. Nonetheless, severe (or even fatal) bleeding may occur at the early stage after metal stent placement, which should be paid particular attention to. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 26, 2018 Category: Gastroenterology Authors: Zhijie Wang, Shengbing Zhao, Qianqian Meng, Shuling Wang, Yan Chen, Fuming Wang, Qiang Li, Jun Yao, Yiqi Du, Zhendong Jin, Yu Bai, Zhaoshen Li, Dong Wang Tags: Biliary and Pancreatic Source Type: research

Ginsenoside Rb1 promotes intestinal epithelial wound healing through extracellular signal ‐regulated kinase and Rho signaling
ConclusionsDaikenchuto and its constituent, ginsenoside Rb1, promoted wound healing. Because mucosal healing is one of the most important therapeutic targets in patients with inflammatory bowel disease, ginsenoside Rb1 may be a novel therapeutic agent against intestinal mucosal damage such as that occurring in intestinal bowel disease. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Yuki Toyokawa, Tomohisa Takagi, Kazuhiko Uchiyama, Katsura Mizushima, Ken Inoue, Chihiro Ushiroda, Saori Kashiwagi, Takahiro Nakano, Yuma Hotta, Makoto Tanaka, Osamu Dohi, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Katada, Kazuhiro Kamada, Tags: Gastroenterology Source Type: research

Clinical Practice of Chinese Medicine Navel Therapy for Chronic Diarrhea: A Literature Review
ConclusionsThe application of Chinese medicine navel therapy could be one of the ideal treatments for chronic diarrhea in the future, especially for children. However, high ‐quality studies are very needed to provide clear evidence. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Meng ‐rui Chen, Jiang Zhao, Shu‐fei Fu, Jia‐qi Yu, Xuan Zhang, Qi‐yang Zhang, Zhi‐huan Zhou Tags: Review Source Type: research

Lactulose Hydrogen Breath Test with Test Meal allows discrimination between Functional Gastrointestinal Disorder and Healthy Volunteer
ConclusionsIn this study we demonstrated significant differences in postprandial symptom generation in FD and IBS compared to HV after LHBT. This does not only allow us to discriminate FD/IBS from HV but may also represent a diagnostic and monitoring tool for FD/IBS in the future, including monitoring of treatment effects. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Valeria Schindler, St éphanie Giezendanner, Simon Bütikofer, Fritz Murray, Daniel Runggaldier, Larissa Schnurre, Annina Zweig, Michael Fried, Daniel Pohl Tags: Gastroenterology Source Type: research

Incidence and clinical impact of perianal disease in patients with ulcerative colitis: A nationwide population ‐based study
ConclusionsThe risk of PAD is higher in UC patients than in the general population. UC patients with PAD have distinct clinical features and poor outcomes, as indicated by the greater need for UC ‐related medications and colectomy. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Eun Mi Song, Ho ‐Su Lee, Ye‐Jee Kim, Eun Hye Oh, Nam Seok Ham, Jeongseok Kim, Sung Wook Hwang, Sang Hyoung Park, Dong‐Hoon Yang, Byong Duk Ye, Jeong‐Sik Byeon, Seung‐Jae Myung, Suk‐Kyun Yang Tags: Gastroenterology Source Type: research

Risk of skin cancers in thiopurines ‐treated and thiopurines‐untreated patients with inflammatory bowel disease: A systematic review and meta‐analysis
ConclusionExposition of thiopurines in patients with IBD is associated with a higher risk of skin cancer. Routine skin screening and daily skin protective practice are recommended for these patients. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Shao ‐Zhuo Huang, Zhi‐Cheng Liu, Wei‐Xin Liao, Jun‐Xiao Wei, Xiao‐Wen Huang, Chen Yang, Yu‐Han Xia, Lu Li, Chao Ye, Shi‐Xue Dai Tags: Meta Analysis and Systematic Review Source Type: research

Hepatobiliary and Pancreatic: Pyoderma gangrenosum of the pancreas successfully treated with infliximab
Journal of Gastroenterology and Hepatology, EarlyView. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: N Deprez, F Dedeurwaerdere, L Desomer, D De Wulf Tags: Education and Imaging Source Type: research

Unique patterns of glycosylation in immunoglobulin subclass G4 ‐related disease and primary sclerosing cholangitis
ConclusionWe report the first study showing unique antibody glycosylation status in a prospective cohort of IgG4 ‐RD and PSC patients, which may determine modulation of the immune system and contribute to disease pathophysiology. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Emma L Culver, Fleur S Bovenkamp, Ninotska I L Derksen, Jana Koers, Tamsin Cargill, Eleanor Barnes, Louise A Neef, Carolien A M Koeleman, Rob C Aalberse, Manfred Wuhrer, Theo Rispens Tags: Biliary and Pancreatic Source Type: research

Clinical validation of the ‘7x7’ questionnaire for patients with functional gastrointestinal disorders
Conclusionsthe ‘7x7’ questionnaire is a convenient, sensitive, and reliable tool for assessing the severity of symptoms and treatment efficacy in people with functional gastrointestinal disorders. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Vladimir Ivashkin, Arkady Sheptulin, Oleg Shifrin, Elena Poluektova, Chavdar Pavlov, Konstantin Ivashkin, Alexandra Drozdova, Olga Lyashenko, Alexandr Korolev Tags: Gastroenterology Source Type: research

Clinical and pathological features of combined hepatocellular ‐cholangiocarcinoma compared with other liver cancers
ConclusionsThe clinical features of CHC, including sex, HBV infection, AFP and PIVKAII levels, were similar to HCC, while its prognosis and pathological features, including vascular invasion and lymph node metastasis, were similar to ICC. CEA levels and tumor size were independent prognostic factors in patients with CHC. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Kazuki Wakizaka, Hideki Yokoo, Toshiya Kamiyama, Masafumi Ohira, Koichi Kato, Yuki Fujii, Ko Sugiyama, Naoki Okada, Takanori Ohata, Akihisa Nagatsu, Shingo Shimada, Tatsuya Orimo, Hirofumi Kamachi, Akinobu Taketomi Tags: Hepatology Source Type: research

Analysis of risk factors and development of scoring system to predict severity of upper gastrointestinal bleeding in children
ConclusionsAmalgamation of risk factors with the scoring system plays an important role in assessing upper gastrointestinal bleeding severity in children. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Wei Zheng, Linmei Jiang, Xinyi Jia, Gao Long, Xiaoli Shu, Mizu Jiang Tags: Gastroenterology Source Type: research

Clinical Features of Idiopathic Portal Hypertension in China: A Retrospective Study of 338 Patients and Literature Review
ConclusionsHigh ‐quality liver biopsy, detailed clinical information, and expert pathologist are necessary for diagnosis of IPH. IPH can occur concurrently with other liver disease such as hepatitis and drug‐induced liver injury. Medication appears to be an important etiological factor for IPH in China. Managem ent approach was largely focused on treatment of portal hypertension and its complications. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Yongliang Sun, Xu Lan, Chen Shao, Tailing Wang, Zhiying Yang Tags: Hepatology Source Type: research

Impact of family history of colorectal cancer on age ‐specific prevalence of colorectal neoplasia
ConclusionAlthough a family history of CRC is a risk factor for NAA, it may affect NAA development from the mid ‐50s and ACRN development from the early 60s. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Chan Hyuk Park, Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Yoon Suk Jung Tags: Gastroenterology Source Type: research

Cost ‐effectiveness of sofosbuvir plus ribavirin therapy for hepatitis C virus genotype 2 infection in South Korea
ConclusionsThe SOF+RBV is a cost ‐effective option for genotype 2 treatment‐naïve CHC patients, especially for the patients with liver cirrhosis in Korea. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Wankyo Chung, Kyung ‐Ah Kim, Eun Sun Jang, Moran Ki, Hwa Young Choi, Sook‐Hyang Jeong Tags: Hepatology Source Type: research

Natural history of gastrointestinal manifestations in vascular Ehlers –Danlos syndrome: A 17‐year retrospective review
ConclusionsVascular Ehlers –Danlos syndrome is characterized not only by bowel perforation but also by a wide variety of GI complications that occur in close to half (41%) of patients. The pattern of GI fragility seems more severe in males and splice‐site variants. Complications of GI surgery are common and are related wi th tissue fragility/friability. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 20, 2018 Category: Gastroenterology Authors: Michael Frank, Salma Adham, Franck Zinzindohou é, Xavier Jeunemaitre Tags: Gastroenterology Source Type: research