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High-resolution uniform MR imaging of finger joints using a dedicated RF coil at 3TEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To develop a dedicated radiofrequency (RF) coil for high-resolution magnetic resonance imaging (MRI) of finger joints at 3T to improve diagnostic evaluation of arthritic diseases.A dedicated cylindrical RF receive coil was developed for imaging finger joints at 3T. A planar coil, a saddle coil, and a 1.5T coil with similar design as the dedicated coil were also constructed to compare imaging performance with the dedicated coil. A phantom was used for quantitative evaluation. Three-dimensional images were obtained on four subjects and a cadaver finger specimen using isotropic resolution of 160 [mu]m in 9:32 minutes. The ima...
Source: Journal of Magnetic Resonance Imaging - October 27, 2009 Category: Radiology Authors: Wingchi E. Kwok, Zhigang You, Johnny Monu, Gwysuk Seo, Christopher Ritchlin Source Type: journals

MRI: A charmed past and an exciting futureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The invention and development of MRI took place under very desirable circumstances. Dr. Lauterbur, a distinguished NMR chemist, conceived of the basic idea. Once this concept was presented to the medical imaging community, a wonderful synergy developed between the two mature disciplines of NMR physical chemistry and medical imaging. This resulted in amazingly rapid progress and acceptance by the clinical community. This adventure is in sharp contrast to the history of x-ray imaging. This began with the accidental discovery of x-rays by Roentgen at the end of the 19th century. Unlike NMR, the basic x-ray mechanism was not u...
Source: Journal of Magnetic Resonance Imaging - October 25, 2009 Category: Radiology Authors: Albert Macovski Tags: Review Article Source Type: journals

Toward a practical protocol for human optic nerve DTI with EPI geometric distortion correctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To develop a practical protocol for diffusion tensor imaging (DTI) of the human optic nerve with echo planar imaging (EPI) geometric distortion correction.A conventional DTI protocol was modified to acquire images with fat and cerebrospinal fluid (CSF) suppression and field inhomogeneity maps of contiguous coronal slices covering the whole brain. The technique was applied to healthy volunteers and multiple sclerosis patients with and without a history of unilateral optic neuritis. DTI measures and optic nerve tractography before and after geometric distortion correction were compared. Diffusion measures from left and right...
Source: Journal of Magnetic Resonance Imaging - October 24, 2009 Category: Radiology Authors: Udomchai Techavipoo, Annette F. Okai, John Lackey, Jianrong Shi, Michael A. Dresner, Thomas P. Leist, Song Lai Tags: Original Research Source Type: journals

Guo H, Au W-Y, Cheung JS, et al. Myocardial T2 quantitation in patients with iron overload at 3 Tesla. J Magn Reson Imaging 2009;30:394-400Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Tags: Erratum Source Type: journals

Functional magnetic resonance imagingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Hui Mao Tags: Book Review Source Type: journals

Personal exposure to static and time-varying magnetic fields during MRI system test proceduresEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To assess personal time-weighted average (TWA) static magnetic field and time-varying magnetic field exposure for several system testing tasks routinely conducted by engineers at an MRI manufacturing plant.Personal exposure was measured using a personal dosimeter that measured B and dB/dt in all three orthogonal directions with a 1 Hz frequency. TWA exposure was calculated and random effects and linear mixed effects models were used to assess exposure levels and variability.Whereas full-body peak (2T) and TWA (200 mT/8 h) exposure limits for the static magnetic field originally proposed by ICNIRP were not exceeded, time-va...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Frank de Vocht, Floris Muller, Hans Engels, Hans Kromhout Tags: Technical Notes Source Type: journals

T1 independent, T2* corrected MRI with accurate spectral modeling for quantification of fat: Validation in a fat-water-SPIO phantomEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To validate a T1-independent, T2*-corrected fat quantification technique that uses accurate spectral modeling of fat using a homogeneous fat-water-SPIO phantom over physiologically expected ranges of fat percentage and T2* decay in the presence of iron overload.A homogeneous gel phantom consisting of vials with known fat-fractions and iron concentrations is described. Fat-fraction imaging was performed using a multiecho chemical shift-based fat-water separation method (IDEAL), and various reconstructions were performed to determine the impact of T2* correction and accurate spectral modeling. Conventional two-point Dixon (i...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Catherine D.G. Hines, Huanzhou Yu, Ann Shimakawa, Charles A. McKenzie, Jean H. Brittain, Scott B. Reeder Tags: Technical Notes Source Type: journals

Effect of contrast media on single-shot echo planar imaging: Implications for abdominal diffusion imagingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The goal of this study was to determine the effect of contrast media on the signal behavior of single-shot echo planar imaging (ssEPI) used for abdominal diffusion imaging.The signal of an ssEPI spin echo sequence in a water phantom with varying concentrations of gadolinium was modeled with Bloch equations and the predicted behavior validated on a phantom at 1.5T. Six volunteers were given gadolinium contrast and signal intensity (SI) time courses for regions of interest (ROIs) in the liver, pancreas, spleen, renal cortex, and medulla were analyzed. Student's t-test was used to compare precontrast SI to 0, 1, 4, 5, 10, and...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Vikas Gulani, Jonathan M. Willatt, Martin Blaimer, Hero K. Hussain, Jeffrey L. Duerk, Mark A. Griswold Tags: Technical Notes Source Type: journals

Impact of papillary and trabecular muscles on quantitative analyses of cardiac function in hypertrophic cardiomyopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To examine the impact of cardiovascular magnetic resonance (CMR) partitioning methods on volumetric analysis in hypertrophic cardiomyopathy (HCM) patients. The standard CMR method for partitioning ventricular myocardium from ventricular cavity includes the myocardial papillary and trabecular muscles in the cavity volume. This approach may misrepresent ventricular mass and volume in patients with HCM due to large papillary muscles and extensive trabeculations.Ventricular volume and mass analyses were performed in 30 patients with HCM using the standard method and a detailed method that excluded papillary and trabecular musc...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Yuchi Han, Eric A. Osborn, Martin S. Maron, Warren J. Manning, Susan B. Yeon Tags: Technical Notes Source Type: journals

Volume-targeted and whole-heart coronary magnetic resonance angiography using an intravascular contrast agentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To compare volume-targeted and whole-heart coronary magnetic resonance angiography (MRA) after the administration of an intravascular contrast agent.Six healthy adult subjects underwent a navigator-gated and -corrected (NAV) free breathing volume-targeted cardiac-triggered inversion recovery (IR) 3D steady-state free precession (SSFP) coronary MRA sequence (t-CMRA) (spatial resolution = 1 × 1 × 3 mm3) and high spatial resolution IR 3D SSFP whole-heart coronary MRA (WH-CMRA) (spatial resolution = 1 × 1 × 2 mm3) after the administration of an intravascular contrast agent B-22956. Subjective and objective image quality pa...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Lijun Tang, Nico Merkle, Michael Schär, Grigorios Korosoglou, Meiyappan Solaiyappan, Vinzenz Hombach, Matthias Stuber Tags: Technical Notes Source Type: journals

Regional corpus callosum morphometry: Effect of field strength and pulse sequenceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To investigate whether scanning at different field strengths and pulse sequences would influence reproducibility of corpus callosum (CC) morphometric measurements as variations in scanning parameters may result in differences in contrast properties between resulting images that are independent of the underlying tissue but rather reflect the physics of the imaging process.Ten subjects were scanned twice at 3T using magnetization-prepared rapid gradient-echo imaging (MPRAGE) and modified driven equilibrium Fourier transform (MDEFT) sequences and once at 1.5T using MPRAGE. Cross-sectional area measurements of four callosal re...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Ihssan A. Abdul-Kareem, Andrej Stancak, Laura M. Parkes, Vanessa Sluming Tags: Technical Notes Source Type: journals

Imaging of the walls of saccular cerebral aneurysms with double inversion recovery black-blood sequenceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we evaluated the wall of saccular cerebral aneurysms (SCAs) using two-dimensional double inversion recovery black-blood sequence (BBDI). We examined 14 patients with an unruptured SCA (USCA). The BBDI was peripheral-pulse gated, and was acquired during the mid-diastolic period. We evaluated whether the aneurysmal wall could be visualized with BBDI, and the wall thickness in the neck and dome portion of the aneurysm was measured in cases with acceptable imaging quality. BBDI demonstrated the USCA walls in ten patients. In four patients, the USCA walls were poorly delineated from the adjacent brain parenchyma ...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Ji Kang Park, Chang Sub Lee, Ki Bum Sim, Ji Soon Huh, Jung Cheol Park Tags: Clinical Note Source Type: journals

Minimization of Nyquist ghosting for echo-planar imaging at ultra-high fields based on a "negative readout gradient" strategyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To improve the traditional Nyquist ghost correction approach in echo planar imaging (EPI) at high fields, via schemes based on the reversal of the EPI readout gradient polarity for every other volume throughout a functional magnetic resonance imaging (fMRI) acquisition train.An EPI sequence in which the readout gradient was inverted every other volume was implemented on two ultrahigh-field systems. Phantom images and fMRI data were acquired to evaluate ghost intensities and the presence of false-positive blood oxygenation level-dependent (BOLD) signal with and without ghost correction. Three different algorithms for ghost ...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Wietske van der Zwaag, José P. Marques, Hongxia Lei, Nathalie Just, Tobias Kober, Rolf Gruetter Tags: Original Research Source Type: journals

Measurement of R1 dynamics using sliding window-DESPOTEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To measure longitudinal relaxation rate (R1) changes during contrast agent studies using a driven equilibrium single pulse observation of T1 (DESPOT) method with a sliding window (sw) acquisition.A sw-DESPOT technique was implemented that uses several three-dimensional (3D) image data sets to calculate R1 with a temporal resolution of only a single data set. Different sources of systematic errors were studied in simulations, and the technique was tested in a tumor-bearing mouse using an intravascular contrast agent.Consistent concentration distributions of the CA were calculated with a temporal resolution of 10 s.Sw-DESPOT...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Jessica Schulz, Matthias Korn, Eva C. Woenne, Reiner Umathum, Andreas Briel, Arne Hengerer, Wolfhard Semmler, Michael Bock Tags: Original Research Source Type: journals

Optimized glutamate detection at 3TEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To identify the pulse sequence and acquisition parameters that result in the most accurate and repeatable measurements of glutamate (Glu) concentration in the brain at 3T.Simulations were performed to compare the accuracy and repeatability of 11 pulse sequences and acquisition parameters, within four general classes (PRESS, STEAM, Carr-Purcell PRESS [CPRESS] and TE averaged PRESS [JPRESS]), the majority of which were previously suggested as optimal for Glu detection. Three of the simulated acquisitions were implemented in a clinical scanner and measures of repeatability in vivo were compared to their simulated values.Good ...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Ileana Hancu Tags: Original Research Source Type: journals

Development and application of magnetic resonance elastography of the normal and pathological thyroid gland in vivoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To noninvasively assess the shear stiffness of the thyroid gland in vivo in order to determine whether magnetic resonance elastography (MRE) might hold clinical utility in the diagnosis of thyroid disease.Quantitative parametric images of thyroid stiffness in normal volunteers and patients were produced and quantitative stiffness values measured. Average gland stiffness was determined by region of interest analysis of the parametric images. This technique was used to assess stiffness of the thyroid in normal individuals (n = 12), patients with Hashimoto's thyroiditis (HT; n = 5), and patients with a solitary benign (n = 8)...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Mark M. Bahn, Michael D. Brennan, Rebecca S. Bahn, Diana S. Dean, Jennifer L. Kugel, Richard L. Ehman Tags: Original Research Source Type: journals

Cross-validation of magnetic resonance elastography and ultrasound-based transient elastography: A preliminary phantom studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, 19 well-characterized phantoms with a range of stiffness values were measured by two clinical devices (a Fibroscan and an MRE system based respectively on the UTE and MRE techniques) successively with the operators double-blinded.Statistical analysis showed that the correlation coefficient was r2 = 0.93 between MRE and UTE, and there was no evidence of a systematic difference between them within the range of stiffnesses examined.These two noninvasive methods, MRE and UTE, provide clinicians with important new options for improving patient care regarding liver diseases in terms of the diagnosis, prognosis, an...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Jennifer Oudry, Jun Chen, Kevin J. Glaser, Véronique Miette, Laurent Sandrin, Richard L. Ehman Tags: Original Research Source Type: journals

MR imaging in Duchenne muscular dystrophy: Quantification of T1-weighted signal, contrast uptake, and the effects of exerciseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To quantify the differences between normal and corticosteroid-treated Duchenne muscular dystrophy (DMD) lower limb muscle using signal intensity measurements on T1-weighted and gadolinium contrast-enhanced images and by measurement of muscle T2 values, and to investigate the effect of exercise.Eleven ambulant boys with DMD were imaged at 3 Tesla (T1-weighted, gadolinium enhancement and T2 measurement) before stepping exercise and again (gadolinium, T2 measurement) 4 days later and were compared with five healthy controls imaged 4 days before and after stepping exercise. Muscle region-of-interest signal intensities were ref...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Penelope Garrood, Kieren G. Hollingsworth, Michelle Eagle, Benjamin S. Aribisala, Daniel Birchall, Kate Bushby, Volker Straub Tags: Original Research Source Type: journals

Comparison of methods to assess quadriceps muscle volume using magnetic resonance imagingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To compare the precision of four methods to estimate the volume of quadriceps muscles using axial MRI.Entire legs of 10 healthy young subjects were scanned using a 1.5 Tesla magnetic resonance imaging scanner and 4-mm-thick sections without any gaps. Quadriceps muscles were outlined on all of the slices to obtain the MRI reference standard measure of quadriceps muscle volume. This MRI reference standard was compared with the volume estimated using (i) the truncated cone formula, (ii) the Cavalieri method, (iii) a cubic spline interpolation of missing cross sectional areas, and, (iv) the deformation of a parametric specific...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Antoine Nordez, Erwan Jolivet, Ingrid Südhoff, Dominique Bonneau, Jacques A. de Guise, Wafa Skalli Tags: Original Research Source Type: journals

Assessment of osteoarthritis in hips with femoroacetabular impingement using delayed gadolinium enhanced MRI of cartilageEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To determine the feasibility of assessing early osteoarthritis (OA) in hips with femoroacetabular impingement (FAI) using delayed Gadolinium enhanced MRI of Cartilage (dGEMRIC).Thirty-seven hips in 30 patients who had a dGEMRIC scan and radiographic evidence of FAI were identified. Clinical symptoms were assessed. Radiographic measurements were performed to determine acetabular and femoral morphology. The severity of radiographic OA was determined using Tönnis grade and minimum joint space width (JSW). On MRI, the alpha angle was measured on the sagittal oblique slices. Correlations between dGEMRIC index, patient symptoms...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Rebecca H. Jessel, Christoph Zilkens, Carl Tiderius, Marcel Dudda, Tallal Charles Mamisch, Young-Jo Kim Tags: Original Research Source Type: journals

Contrast-enhanced intracranial magnetic resonance angiography with a spherical shells trajectory and online gridding reconstructionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To evaluate the feasibility of applying the shells trajectory to single-phase contrast-enhanced magnetic resonance angiography.Several methods were developed to overcome the challenges of the clinical implementation of shells including off-resonance blurring (eg, from lipid signal), aliasing artifacts, and long reconstruction times. These methods included: 1) variable TR with variable readout length to reduce fat signal and off-resonance blurring; 2) variable sampling density to suppress aliasing artifacts while minimizing acquisition time penalty; and 3) an online 3D gridding algorithm that reconstructed an 8-channel, 240...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Yunhong Shu, Matt A. Bernstein, John Huston III, Dan Rettmann Tags: Original Research Source Type: journals

Increased volume of coverage for abdominal contrast-enhanced MR angiography with two-dimensional autocalibrating parallel imaging: Initial experience at 3.0 TeslaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To assess the feasibility and the quality of abdominal three-dimensional (3D) contrast enhanced MR angiograms acquired at 3.0 Tesla (T) using a new 2D-accelerated autocalibrating parallel reconstruction method for Cartesian sampling (2D-ARC).With institutional review board approval and written informed consent, a prospective trial in 6 normal healthy volunteers and 23 patients referred for evaluation of suspected renovascular disease was performed. The volunteers underwent abdominal MRA with and without 2D-ARC acceleration. Images were evaluated independently by two blinded vascular radiologists in randomized order. Vessel...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Darren P. Lum, Reed F. Busse, Christopher J. Francois, Anja C. Brau, Philip J. Beatty, Joshua Huff, Jean H. Brittain, Scott B. Reeder Tags: Original Research Source Type: journals

Highly accelerated first-pass contrast-enhanced magnetic resonance angiography of the peripheral vasculature: Comparison of gadofosveset trisodium with gadopentetate dimeglumine contrast agentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To investigate the blood pool agent gadofosveset trisodium for first-pass, dynamic peripheral contrast-enhanced magnetic resonance angiography (pMRA), and compare the results with a conventional gadolinium contrast agent.A total of 16 patients were imaged at 1.5T using a prototype peripheral vascular coil with high SENSE acceleration. Five received gadopentetate dimeglumine ([ap]0.25 mmol/kg), and 11 received gadofosveset trisodium (five standard-dose 0.03 mmol/kg, six high-dose 0.05 mmol/kg). Quantitative contrast-enhancement and qualitative image quality evaluation was compared between agents and doses.High-quality diagn...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Jeffrey H. Maki, Maisie Wang, Gregory J. Wilson, Matthew G. Shutske, Tim Leiner Tags: Original Research Source Type: journals

Vessel size imaging using dual contrast agent injectionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study suggests that VSI with a dual injection method is a feasible technique for estimating microvascular calibers of normal tissues and brain tumors in clinical scanners. J. Magn. Reson. Imaging 2009;30:1078-1084. © 2009 Wiley-Liss, Inc. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Yuan-Yu Hsu, Wei-Shan Yang, Kun-Eng Lim, Ho-Ling Liu Tags: Original Research Source Type: journals

Diffusion-weighted imaging of human carotid artery using 2D single-shot interleaved multislice inner volume diffusion-weighted echo planar imaging (2D ss-IMIV-DWEPI) at 3T: Diffusion measurement in atherosclerotic plaqueEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To determine if 2D single-shot interleaved multislice inner volume diffusion-weighted echo planar imaging (ss-IMIV-DWEPI) can be used to obtain quantitative diffusion measurements that can assist in the identification of plaque components in the cervical carotid artery.The 2D ss-DWEPI sequence was combined with interleaved multislice inner volume region localization to obtain diffusion weighted images with 1 mm in-plane resolution and 2 mm slice thickness. Eleven subjects, six of whom have carotid plaque, were studied with this technique. The apparent diffusion coefficient (ADC) images were calculated using DW images with ...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Seong-Eun Kim, Eun-Kee Jeong, Xian-Feng Shi, Glen Morrell, Gerald S. Treiman, Dennis L. Parker Tags: Original Research Source Type: journals

Optimization of the contrast dose and injection rates in whole-body MR angiography at 3.0TEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study demonstrates that reducing the contrast dose at 3.0T can result in an increase in the CNR in the vessels of interest without significantly affecting the SNR. J. Magn. Reson. Imaging 2009;30:1059-1067. © 2009 Wiley-Liss, Inc. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Shelley A. Waugh, P. Guntur Ramkumar, Stephen J. Gandy, R. Stephen Nicholas, Patricia Martin, Jill J.F. Belch, Allan D. Struthers, J. Graeme Houston Tags: Original Research Source Type: journals

MRI signal intensity based B-Spline nonrigid registration for pre- and intraoperative imaging during prostate brachytherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To apply an intensity-based nonrigid registration algorithm to MRI-guided prostate brachytherapy clinical data and to assess its accuracy.A nonrigid registration of preoperative MRI to intraoperative MRI images was carried out in 16 cases using a Basis-Spline algorithm in a retrospective manner. The registration was assessed qualitatively by experts' visual inspection and quantitatively by measuring the Dice similarity coefficient (DSC) for total gland (TG), central gland (CG), and peripheral zone (PZ), the mutual information (MI) metric, and the fiducial registration error (FRE) between corresponding anatomical landmarks ...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Sota Oguro, Junichi Tokuda, Haytham Elhawary, Steven Haker, Ron Kikinis, Clare M.C. Tempany, Nobuhiko Hata Tags: Original Research Source Type: journals

Liver parenchymal enhancement of hepatocyte-phase images in Gd-EOB-DTPA-enhanced MR imaging: Which biological markers of the liver function affect the enhancement?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To clarify the factors that predict enhancement of the liver parenchyma in hepatocyte-phase of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced MR imaging.Gd-EOB-DTPA-enhanced hepatocyte-phase MR images of 198 patients with chronic liver diseases (Child-Pugh class A in 112 patients, class B in 74 patients, and class C in 12 patients) were retrospectively analyzed. The hepatocyte-phase images were obtained using fat-suppressed T1-weighted gradient-echo images with a 3D acquisition sequence 10 min and 20 min after IV administration of Gd-EOB-DTPA (0.025 mmol/kg body weight). The quantitative ...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Utaroh Motosugi, Tomoaki Ichikawa, Hironobu Sou, Katsuhiro Sano, Licht Tominaga, Takatoshi Kitamura, Tsutomu Araki Tags: Original Research Source Type: journals

Magnetic resonance T2-relaxometry and 2D L-correlated spectroscopy in patients with minimal hepatic encephalopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To evaluate T2-relaxation changes in patients with minimal hepatic encephalopathy (MHE) using T2 relaxometry and to correlate T2 values with brain metabolites evaluated using 2D magnetic resonance spectroscopy (MRS).Eight MHE patients and 13 healthy subjects were evaluated using T2 relaxometry, and eight patients and nine healthy subjects underwent 2D MRS in right frontal and left occipital regions. Whole-brain T2-relaxation maps were compared between MHE and control subjects using analysis-of-covariance, with age and gender included as covariates. T2 values derived from the right frontal and left occipital lobes were corr...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Aparna Singhal, Rajakumar Nagarajan, Rajesh Kumar, Amir Huda, Rakesh K. Gupta, M. Albert Thomas Tags: Original Research Source Type: journals

Diffusion-weighted MR imaging of the liver at 3.0 Tesla using TRacking Only Navigator echo (TRON): A feasibility studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To assess the feasibility of TRacking Only Navigator echo (TRON) for diffusion-weighted magnetic resonance imaging (DWI) of the liver at 3.0T.Ten volunteers underwent TRON, respiratory triggered, and free breathing DWI of the liver at 3.0 Tesla (T). Scan times were measured. Image sharpness, degree of stair-step and stripe artifacts for the three methods were assessed by two observers.Mean scan times of TRON and respiratory triggered DWI relative to free breathing DWI were 34% and 145% longer respectively. In four of eight comparisons (two observers, two b-values, two slice orientations), TRON DWI image sharpness was signi...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Marko K. Ivancevic, Thomas C. Kwee, Taro Takahara, Tetsuo Ogino, Hero K. Hussain, Peter S. Liu, Thomas L. Chenevert Tags: Original Research Source Type: journals

Diffusion-weighted MRI: A new tool for the diagnosis of fistula in anoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To retrospectively determine the additional value of diffusion-weighted magnetic resonance imaging (MRI) to T2-weighted imaging in the evaluation of anal fistulae in comparison with gadolinium (Gd)-enhanced imaging.Thirteen patients (mean age, 35.2 years) with 20 anal fistulae were included. The protocol consisted of fat-suppressed T2-weighted fast spin-echo, diffusion-weighted single-shot echo-planar (b factors 0 and 800 s/mm2), and fat-suppressed Gd-enhanced T1-weighted gradient echo sequences. Two radiologists evaluated images in consensus.Eighteen (90%) fistulae were detected on T2-weighted images, and 19 (95%) and 19 ...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Masatoshi Hori, Aytekin Oto, Sarah Orrin, Kenji Suzuki, Richard L. Baron Tags: Original Research Source Type: journals

Resovist enhanced MR imaging of the liver: Does quantitative assessment help in focal lesion classification and characterization?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To improve characterization of focal liver lesions by a prospective quantitative analysis of percentage signal intensity change, in dynamic and late phases after slow (0.5 mL/s) Resovist administration.Seventy-three patients were submitted on clinical indication to MR examination with Resovist. Signal intensity of 92 detected focal lesions (5-80 mm) were measured with regions of interest and normalized to paravertebral muscle in arterial, portal, equilibrium and T1/T2 late phases, by two observers in conference. Five values of percentage variations per patient were obtained and statistically evaluated.The enhancement obtai...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Lucia Santoro, Luigi Grazioli, Antonella Filippone, Emanuele Grassedonio, Giacomo Belli, Stefano Colagrande Tags: Original Research Source Type: journals

High-b-value diffusion-weighted MR imaging of hepatocellular lesions: Estimation of grade of malignancy of hepatocellular carcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To evaluate the effectiveness of diffusion-weighted magnetic resonance imaging (DWI) in estimating the grade of malignancy of hepatocellular carcinoma.Dynamic contrast-enhanced computed tomography (CE-CT) and DWI (b value, 1000 s/mm2) were performed on 73 patients. Using DW images, the lesions were classified as "visible" or "invisible." The apparent diffusion coefficient (ADC) of the lesions was measured. Furthermore, the lesions were classified as hypervascular or iso-hypovascular using arterial phase CE-CT images. The image findings for each lesion type were compared.The 73 patients had 98 hepatocellular lesions, of whi...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Ali Muhi, Tomoaki Ichikawa, Utaroh Motosugi, Katsuhiro Sano, Masanori Matsuda, Takatoshi Kitamura, Tadao Nakazawa, Tsutomu Araki Tags: Original Research Source Type: journals

Relationship of temporal resolution to diagnostic performance for dynamic contrast enhanced MRI of the breastEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To investigate the relationship between temporal resolution of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and classification of breast lesions as benign versus malignant.Patients underwent T1-weighted DCE MRI with 15 s/acquisition temporal resolution using 1.5 Tesla (n = 48) and 3.0T (n = 33) MRI scanners. Seventy-nine patients had pathologically proven diagnosis and 2 had 2 years follow-up showing no change in lesion size. The temporal resolution of DCE MRI was systematically reduced as a postprocessing step from 15 to 30, 45, and 60 s/acquisition by eliminating intermediate time points. Average wash...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Riham H. El Khouli, Katarzyna J. Macura, Peter B. Barker, Mohamed R. Habba, Michael A. Jacobs, David A. Bluemke Tags: Original Research Source Type: journals

Principal component analysis of breast DCE-MRI adjusted with a model-based methodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To investigate a fast, objective, and standardized method for analyzing breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) applying principal component analysis (PCA) adjusted with a model-based method.3D gradient-echo DCE breast images of 31 malignant and 38 benign lesions, recorded on a 1.5T scanner, were retrospectively analyzed by PCA and by the model-based three-timepoints (3TP) method.Intensity-scaled (IS) and enhancement-scaled (ES) datasets were reduced by PCA yielding a first IS-eigenvector that captured the signal variation between fat and fibroglandular tissue; two IS-eigenvectors and the two ...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Erez Eyal, Daria Badikhi, Edna Furman-Haran, Fredrick Kelcz, Kevin J. Kirshenbaum, Hadassa Degani Tags: Original Research Source Type: journals

Assessment of hyperpolarized 3He lung MRI for regional evaluation of interventional therapy: A pilot study in pediatric cystic fibrosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To determine whether regional changes in lung ventilation in a group of pediatric cystic fibrosis (CF) patients following a course of chest physiotherapy could be detected with 3He MRI.The reproducibility of lung ventilation volume measurements obtained with 3He lung magnetic resonance imaging (MRI) was established in a group of five children with CF age 6-15 years. The same methodology was then used to evaluate whether standard chest physiotherapy (percussion and drainage) had any immediate effect on regional ventilated lung volumes in a further group of nine age-matched CF children (5-15 years).Global lung ventilation vo...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Neil Woodhouse, Jim M. Wild, Edwin J.R. van Beek, Nigel Hoggard, Nicki Barker, Christopher J. Taylor Tags: Original Research Source Type: journals

Utility of phase contrast MR imaging for assessment of pulmonary flow and pressure estimation in patients with pulmonary hypertension: Comparison with right heart catheterization and echocardiographyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To compare the utility of phase contrast MR imaging (PC-MRI) for assessment of pulmonary flow and pressure estimation with that of right heart catheterization and echocardiography (cardiac US) in patients with pulmonary arterial hypertension (PAH).Twenty consecutive patients with suspected PAH underwent PC-MRI, cardiac US, and right heart catheterization. In each patient, PC-MRI was acquired by cine 2D-PC method on a 1.5 Tesla scanner, and stroke volume (SV) and pulmonary arterial systolic pressure (PASP) were assessed by using the modified Bernoulli's equation. To evaluate the agreements of SV and PASP among the three met...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Munenobu Nogami, Yoshiharu Ohno, Hisanobu Koyama, Atsushi Kono, Daisuke Takenaka, Toshiya Kataoka, Hiroya Kawai, Hideaki Kawamitsu, Yumiko Onishi, Keiko Matsumoto, Sumiaki Matsumoto, Kazuro Sugimura Tags: Original Research Source Type: journals

Shorter difference between myocardium and blood optimal inversion time suggests diffuse fibrosis in dilated cardiomyopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To find evidence of diffuse fibrosis in dilated cardiomyopathy (DCM) patients by comparing measurements on clinical late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) studies between DCM and healthy subjects.LGE-CMR and the Look-Locker images from 20 DCM patients and 17 healthy controls were analyzed. Blood signal-to-noise ratio (SNR), myocardium SNR, and blood-to-myocardium contrast-to-noise ratio (CNR) were measured on the LGE-CMR images. The optimal inversion time (TI) to null blood and myocardium was determined on the Look-Locker images. The postcontrast T1 was estimated using a phantom study tha...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Yuchi Han, Dana C. Peters, Basem Dokhan, Warren J. Manning Tags: Original Research Source Type: journals

Cardiac function by MRI in congenital heart disease: Impact of consensus training on interinstitutional varianceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To investigate the impact of interinstitutional variance (=interobserver variance between institutions) for volumetric and flow cardiac MR (CMR) data and if training on image reading could improve bias.In a three-center study, a total of 32 adults with repaired Tetralogy of Fallot and 23 controls underwent CMR using standardized protocols for ventricular volumes/mass (by transverse and short-axis cine-MRI) and pulmonary/aortic blood flow by velocity-encoded MRI (VEC-MRI). Data were analyzed blinded and independently in each institution by experienced readers. Interinstitutional variance was determined before/after training...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Philipp Beerbaum, Peter Barth, Siegfried Kropf, Samir Sarikouch, Andrea Kelter-Kloepping, Diana Franke, Matthias Gutberlet, Titus Kuehne Tags: Original Research Source Type: journals

3D velocity quantification in the heart: Improvements by 3D PC-SSFPEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To test whether a 3D imaging sequence with phase contrast (PC) velocity encoding based on steady-state free precession (SSFP) improves 3D velocity quantification in the heart compared to the currently available gradient echo (GE) approach.The 3D PC-SSFP sequence with 1D velocity encoding was compared at the mitral valve in 12 healthy subjects with 3D PC-GE at 1.5T. Velocity measurements, velocity-to-noise-ratio efficiency (VNReff), intra- and interobserver variability of area and velocity measurements, contrast-to-noise-ratio (CNR), and artifact sensitivity were evaluated in both long- and short-axis orientation.Descending...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Marijn P. Rolf, Mark B.M. Hofman, Joost P.A. Kuijer, Albert C. van Rossum, Rob M. Heethaar Tags: Original Research Source Type: journals

Prediction of hemorrhagic transformation in acute ischemic stroke using texture analysis of postcontrast T1-weighted MR imagesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To test the hypothesis that texture analysis of postcontrast T1-weighted MR images will predict hemorrhagic transformation (HT) in patients with acute ischemic stroke (AIS) with better accuracy than visual evidence of contrast-enhancement (VE).Thirty-four AIS patients were examined within 3.5 ± 1.5 h after stroke. T1-weighted MR images were acquired 19 ± 7 min postcontrast injection. HT was determined by follow-up imaging at 24-72 h. Postcontrast images were evaluated for VE. Four second-order textural features were extracted (f1, f2, f3, and f9) for each patient. Receiver operating characteristic (ROC) curves were const...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Andrea Kassner, Fang Liu, Rebecca E. Thornhill, George Tomlinson, David J. Mikulis Tags: Original Research Source Type: journals

7 Tesla MR imaging of the human eye in vivoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To develop a protocol which optimizes contrast, resolution and scan time for three-dimensional (3D) imaging of the human eye in vivo using a 7 Tesla (T) scanner and custom radio frequency (RF) coil.Initial testing was conducted to reduce motion and susceptibility artifacts. Three-dimensional FFE and IR-TFE images were obtained with variable flip angles and TI times. T1 measurements were made and numerical simulations were performed to determine the ideal contrast of certain ocular structures. Studies were performed to optimize resolution and signal-to-noise ratio (SNR) with scan times from 20 s to 5 min.Motion and suscepti...
Source: Journal of Magnetic Resonance Imaging - October 23, 2009 Category: Radiology Authors: Kathryn Richdale, Peter Wassenaar, Katharine Teal Bluestein, Amir Abduljalil, John A. Christoforidis, Titus Lanz, Michael V. Knopp, Petra Schmalbrock Tags: Original Research Source Type: journals

Expression of appreciation: 2008 JMRI reviewersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - September 27, 2009 Category: Radiology Tags: Expression of Appreciation Source Type: journals

Book reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - September 27, 2009 Category: Radiology Authors: Bobby Kalb Tags: Book Review Source Type: journals

ResponseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - September 27, 2009 Category: Radiology Authors: Ilana R. Leppert, C. Robert Almli, Robert C. McKinstry, Robert V. Mulkern, Carlo Pierpaoli, Micheal J. Rivkin, G. Bruce Pike, The Brain Development Cooperative Group Tags: Letter to the Editor Source Type: journals

T2 relaxometry of maturing brainsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - September 27, 2009 Category: Radiology Authors: Xiao-Qi Ding Tags: Letter to the Editor Source Type: journals

Investigation using an HER-2/neu transgenic mouse model of a newly developed MR contrast agent with the effect of an antitumor drugEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To assess whether Gd-DTPA-Gel-Cis, a conjugate of gadolinium (Gd), cis diamminedichloroplatinum (Cis), diethylenetriaminepentaacetic acid (DTPA)-dianhydride, and bovine gelatin (Gel) can be used as an intravascular contrast agent at MRI and as an antitumor cell proliferation agent in vitro.We injected Gd-DTPA-Gel-Cis (200 mg/mL) into the caudal vein of female HER-2/neu transgenic mice with spontaneous mammary tumors. The tumor signal intensity was measured with a 0.3 Tesla MRI scanner. HER-2/neu-expressing NT cells were treated with Gd-DTPA-Gel-Cis (5 [mu]M cisplatin, 200 mg/mL Gel), Cis alone (5 [mu]M cisplatin), or Gel a...
Source: Journal of Magnetic Resonance Imaging - September 27, 2009 Category: Radiology Authors: Akinaga Sonoda, Norihisa Nitta, Shinich Ohta, Ayumi Nitta-Seko, Satoshi Murata, Jun-ichiro Jo, Yasuhiko Tabata, Masashi Takahashi, Toru Tani, Kiyoshi Murata Tags: Technical Notes Source Type: journals

Cellular magnetic resonance imaging for the differentiation of infectious and degenerative vertebral disorders: Preliminary resultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To evaluate macrophage imaging using the ability of superparamagnetic iron oxide (SPIO) magnetic resonance imaging (MRI) to differentiate infectious vertebral osteomyelitis and degenerative disk-related inflammatory endplates. The in vivo demonstration of the different distribution of macrophages in those two disorders may allow a more accurate characterization of vertebral endplate abnormalities than classical extracellular MR changes.In 12 patients with endplate abnormalities (six cases of bacteriologically proven spondylodiscitis, six cases of disk degeneration-related endplate changes), two MRI sessions were realized: ...
Source: Journal of Magnetic Resonance Imaging - September 27, 2009 Category: Radiology Authors: Guillaume Bierry, François Jehl, Nathalie Holl, Jean Sibilia, Sébastien Froelich, Pierre Froehlig, Jean-Louis Dietemann, Stéphane Kremer Tags: Technical Notes Source Type: journals

High resolution fast T1 mapping technique for dGEMRICEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To determine the feasibility of using a high resolution isotropic three-dimensional (3D) fast T1 mapping sequence for delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) to assess osteoarthritis in the hip.T1 maps of the hip were acquired using both low and high resolution techniques following the administration of 0.2 mmol/kg Gd-DTPA2- in 35 patients. Both T1 maps were generated from two separate spoiled GRE images. The high resolution T1 map was reconstructed in the anatomically equivalent plane as the low resolution map. T1 values from the equivalent anatomic regions containing femoral and acetabular cartilages were ...
Source: Journal of Magnetic Resonance Imaging - September 27, 2009 Category: Radiology Authors: Samir Sur, Tallal Charles Mamisch, Timothy Hughes, Young-Jo Kim Tags: Technical Notes Source Type: journals

In vivo DTI assessment of hepatic ischemia reperfusion injury in an experimental rat modelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To investigate hepatic ischemia reperfusion injury (IRI) using diffusion tensor imaging (DTI).Ten Sprague-Dawley rats were scanned at 7 Tesla (T) with DTI using b-value of 1000 s/mm2 and 6 gradient directions before, 2 h, and 1 day after 30-min total hepatic IRI. Apparent diffusion coefficient or mean diffusivity (MD), directional diffusivities and fractional anisotropy (FA) were measured. Seven of the animals were also examined with spin-echo echo-planar diffusion-weighted imaging (DWI) with seven b-values up to 2000 s/mm2 to estimate the true diffusion coefficient (D), blood pseudodiffusion coefficient (D*), and perfusio...
Source: Journal of Magnetic Resonance Imaging - September 27, 2009 Category: Radiology Authors: Jerry S. Cheung, Shu Juan Fan, April M. Chow, Edward S. Hui, Ed X. Wu Tags: Technical Notes Source Type: journals