[ASAP] Novel H < sub > 2 < /sub > S ‑Releasing Bifunctional Antihistamine Molecules with Improved Antipruritic and Reduced Sedative Actions
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00321 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 6, 2023 Category: Chemistry Authors: Ivi Antoniadou, Maria Georgiou, Yannis Dotsikas, Alexandra Lamprou, Nikolaos Lougiakis, Nicole Pouli, Nikolaos Karousis, Yannis Loukas, Ioulia Tseti, Panagiotis Marakos, and Andreas Papapetropoulos Source Type: research
[ASAP] Exploring the Anticancer Activity of Tamoxifen-Based Metal Complexes Targeting Mitochondria
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00617 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 6, 2023 Category: Chemistry Authors: Valeria Scalcon, Riccardo Bonsignore, Jana Aupic ̌, Sophie R. Thomas, Alessandra Folda, Alexandra A. Heidecker, Alexander Pöthig, Alessandra Magistrato, Angela Casini, and Maria Pia Rigobello Source Type: research
[ASAP] Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00213 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 6, 2023 Category: Chemistry Authors: Siyu He, Xianglin Chu, Yujia Wu, Jiheng Jiang, Pengfei Fang, Yuting Chen, Yang Liu, Zhixia Qiu, Yibei Xiao, Zhiyu Li, Di Pan, Qian Zhang, Huanfang Xie, Shuaishuai Xing, Feng Feng & , Wenyuan Liu, Qinglong Guo, Li Zhao, Peng Yang, and Haopeng Sun Source Type: research
[ASAP] Ir(III) Compounds Containing a Terdentate Ligand Are Potent Inhibitors of Proliferation and Effective Antimetastatic Agents in Aggressive Triple-Negative Breast Cancer Cells
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00586 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 6, 2023 Category: Chemistry Authors: Vojtech Novohradsky, Alicia Marco, Lenka Markova, Natalia Cutillas, Jose ́ Ruiz, and Viktor Brabec Source Type: research
[ASAP] Dimer Peptide Ligands of Vascular Endothelial Growth Factor: Optimizing Linker Length for High Affinity and Antiangiogenic Activity
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00561 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 6, 2023 Category: Chemistry Authors: Xiaoqing Ye, Jean-Franc ̧ois Gaucher, Haofeng Hu, Lei Wang, and Sylvain Broussy Source Type: research
[ASAP] Systematic Study of Heteroarene Stacking Using a Congeneric Set of Molecular Glues for Procaspase ‑6
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00590 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 5, 2023 Category: Chemistry Authors: Takaya Togo, Linh Tram, Laura G. Denton, Xochina ElHilali-Pollard, Jun Gu, Jinglei Jiang, Chenglei Liu, Yan Zhao, Yanlong Zhao, Yinzhe Zheng, Yunping Zheng, Jingjing Yang, Panpan Fan, Michelle R. Arkin, Harri Ha ̈rmä, Deqian Sun, Stacie S. Canan̂, Ste Source Type: research
[ASAP] Discovery of Cycloalkyl[ < italic toggle="yes" > c < /italic > ]thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2 α Inhibitors
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00332 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 5, 2023 Category: Chemistry Authors: Hans-Peter Buchstaller, Ada Sala-Hojman, Matthias Leiendecker, Joachim Albers, Uwe Anlauf, Nina Berges, Liming Dong, Thomas Fuch ß, Martina Germann, Tim Knehans, Mireille Krier, Marc Lecomte, Daniel Müller, Sandra R. Müller, Birgitta Leuthner, Ralph Source Type: research
[ASAP] Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00550 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 5, 2023 Category: Chemistry Authors: Ingo V. Hartung, Joachim Rudolph, Mary M. Mader, Monique P. C. Mulder, and Paul Workman Source Type: research
[ASAP] Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00737 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 3, 2023 Category: Chemistry Authors: Daiki Yamane, Ryo Tetsukawa, Naoki Zenmyo, Kaori Tabata, Yuya Yoshida, Naoya Matsunaga, Naoya Shindo, and Akio Ojida Source Type: research
[ASAP] Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS < sup > G12C < /sup > with Demonstrable CNS Penetration
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00746 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 3, 2023 Category: Chemistry Authors: Jason G. Kettle, Sharan K. Bagal, Derek Barratt, Michael S. Bodnarchuk, Scott Boyd, Erin Braybrooke, Jason Breed, Doyle J. Cassar, Sabina Cosulich, Michael Davies, Nichola L. Davies, Chao Deng, Andrew Eatherton, Laura Evans, Lyman J. Feron, Shaun Fillery, Source Type: research
[ASAP] Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00705 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - July 3, 2023 Category: Chemistry Authors: Simone Bonazzi, Audrey Gray, Noel M. Thomsen, Jonathan Biag, Nancy Labbe-Giguere, Erin P. Keaney, Hasnain A. Malik, Yingchuan Sun, Jill Nunez, Rajeshri G. Karki, Mark Knapp, Robert Elling, John Fuller, Gwynn Pardee, Lucas Craig, Ketthsy Capre, Sarah Salas Source Type: research
[ASAP] High Affinity and FAP-Targeted Radiotracers: A Potential Design Strategy to Improve the Pharmacokinetics and Tumor Uptake for FAP Inhibitors
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00259 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 30, 2023 Category: Chemistry Authors: Yinwen Wang, Hongmei Yuan, Nan Liu, Sufan Tang, Yue Feng, Yang Liu, Ping Cai, Li Xia, Wenlu Zheng, Yue Chen, and Zhijun Zhou Source Type: research
[ASAP] Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00403 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 30, 2023 Category: Chemistry Authors: Bart Kesteleyn, Dorothe ́e Bardiot, Jean-François Bonfanti, Benoît De Boeck, Olivia Goethals, Suzanne J. F. Kaptein, Bart Stoops, Erwin Coesemans, Jérôme Fortin, Philippe Muller, Frédéric Doublet & , Gunter Carlens, Mohamed Koukni, Wim Smets, Source Type: research
[ASAP] Multifunctional Iridium(III) –Platinum(IV) Conjugates as Potent Anticancer Theranostic Agents
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00336 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 30, 2023 Category: Chemistry Authors: Ajay Gupta, Abhishek Kumar Pandey, Titas Mondal, Jaydeep Bhattacharya, and Pijus K. Sasmal Source Type: research
[ASAP] Analysis of Structure –Activity Relationships of Novel Inhibitors of the Macrophage Infectivity Potentiator (Mip) Proteins of < named-content content-type="genus-species" xlink:type="simple" > Neisseria meningitidis < /named-content > , < named-content content-type="genus-species" xlink:type="simple" > Neisseria gonorrhoeae < /named-content > , and < named-content content-type="genus-species" xlink:type="simple" > Burkholderia pseudomallei < /named-content >
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00458 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 30, 2023 Category: Chemistry Authors: Nicolas J. Scheuplein, Nicole M. Bzdyl, Theresa Lohr, Emily A. Kibble, Anja Hasenkopf, Carina Herbst, Mitali Sarkar-Tyson, and Ulrike Holzgrabe Source Type: research
