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Blink rate is associated with drug-induced parkinsonism in patients with severe mental illness, but does not meet requirements to serve as a clinical test: the Curacao extrapyramidal syndromes study XIII
Drug-induced parkinsonism (DIP) has a high prevalence and is associated with poorer quality of life. To find a practical clinical tool to assess DIP in patients with severe mental illness (SMI), the associatio... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - August 25, 2017 Category: Research Authors: Charlotte L. Mentzel, P. Roberto Bakker, Jim van Os, Marjan Drukker, Glenn E. Matroos, Marina A. J. Tijssen and Peter N. van Harten Tags: Research Source Type: research

Work-focused cognitive behavioral intervention for psychological complaints in patients on sick leave due to work-related stress: Results from a randomized controlled trial
Work-related stress is a global problem with negative implications for individuals and society. The purpose of the current study was to evaluate a stress management intervention for patients on sick leave due ... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - August 22, 2017 Category: Research Authors: Vita Ligaya Dalgaard, Lars Peter S ønderbo Andersen, Johan Hviid Andersen, Morten Vejs Willert, Ole Carstensen and David John Glasscock Tags: Research Source Type: research

In vitro aggregating β-lactamase-polyQ chimeras do not induce toxic effects in an in vivo Caenorhabditis elegans model
A series of human diseases are caused by the misfolding and aggregation of specific proteins or peptides into amyloid fibrils; nine of these diseases, referred to as polyglutamine diseases, are associated with... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - August 22, 2017 Category: Research Authors: Roel Van Assche, Charline Borghgraef, Jonathan Vaneyck, Mireille Dumoulin, Liliane Schoofs and Liesbet Temmerman Tags: Research Source Type: research

Polymorphism rs547984 on human chromosome 1q43 is not associated with primary open angle glaucoma in a Saudi cohort
To investigate the association between polymorphism rs547984, located in close proximity to the Zona Pellucida Glycoprotein 4 (ZP4) gene on human chromosome 1q43 and primary open angle glaucoma (POAG). (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - June 26, 2017 Category: Research Authors: Taif A. Azad, Nikhil B. Edward, Altaf A. Kondkar, Hatem Kalantan, Saleh Altuwaijri, Tahira Sultan, Faisal A. Al-Mobarak, Saleh A. Al-Obeidan and Khaled K. Abu-Amero Source Type: research

Behavioral and neural adaptations in response to five weeks of balance training in older adults: a randomized controlled trial
While the positive effect of balance training on age-related impairments in postural stability is well-documented, the neural correlates of such training adaptations in older adults remain poorly understood. T... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - June 13, 2017 Category: Research Authors: Jan Ruffieux, Audrey Mouthon, Martin Keller, Michael W älchli and Wolfgang Taube Source Type: research

Does the placebo effect modulate drug bioavailability? Randomized cross-over studies of three drugs
Medication effect is the sum of its drug, placebo, and drug*placebo interaction effects. It is conceivable that the interaction effect involves modulating drug bioavailability; it was previously observed that ... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - May 23, 2017 Category: Research Authors: Muhammad M Hammami, Ahmed Yusuf, Faduma S. Shire, Rajaa Hussein and Reem Al-Swayeh Source Type: research

Absence of the dermatan sulfate chain of decorin does not affect mouse development
In vitro studies suggest that the multiple functions of decorin are related to both its core protein and its dermatan sulfate chain. To determine the contribution of the dermatan sulfate chain to the functiona... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - April 17, 2017 Category: Research Authors: Pierre Moffatt, Yeqing Geng, Lisa Lamplugh, Antonio Nanci and Peter J. Roughley Source Type: research

The effects of phosphanegold(I) thiolates on the biological properties of Acanthamoeba castellanii belonging to the T4 genotype
Gold compounds have shown promise in the treatment of non-communicable diseases such as rheumatoid arthritis and cancer, and are considered of value as anti-microbial agents against Gram-negative and Gram-posi... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - April 3, 2017 Category: Research Authors: Ruqaiyyah Siddiqui, Farhat Abjani, Chien Ing Yeo, Edward R. T. Tiekink and Naveed Ahmed Khan Source Type: research

Facial cutaneo-mucosal venous malformations can develop independently of mutation of TEK gene but may be associated with excessive expression of Src and p-Src
We aimed to search for mutations in the germline and somatic DNA of the TEK gene and to analyze the expression level of Src and phospho-Src (p-Src) in tumor and healthy tissues from patients with facial cutaneo-m... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - March 20, 2017 Category: Research Authors: Nabila Brahami, Selvakumar Subramaniam, Moudjahed Saleh Al-Ddafari, Cecile Elkaim, Pierre-Olivier Harmand, Badr-Eddine Sari, G érard Lefranc and Mourad Aribi Source Type: research

Experimental silicosis does not aggravate collagen-induced arthritis in mice
To investigate the effect of chronic lung inflammation on the incidence and severity of collagen-induced arthritis in mice. (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - March 13, 2017 Category: Research Authors: Robby Engelmann and Brigitte M üller-Hilke Source Type: research

Erratum to: Do anti-amyloid beta protein antibody cross reactivities confound Alzheimer disease research?
(Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - March 8, 2017 Category: Research Authors: Sally Hunter and Carol Brayne Source Type: research