Correspondence on 'Acute ischemic stroke outcomes in patients with COVID-19: a systematic review and meta-analysis by Ferrone et al
We had the pleasure of reading the article ‘Acute ischemic stroke outcomes in patients with COVID-19: a systematic review and meta-analysis’ by Ferrone et al. with great interest.1 In particular, the reduced odds of home discharge for patients with stroke who have COVID-19 presents an interesting insight into the management challenges while caring for these patients. However, we would like to highlight some concerns about the methodology of the study. Heterogeneity is defined as observed intervention effects being more different from each other than one would expect due to random error (chance) alone.2 For the ...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Muzaffar, T., Danial, A., Ahmed, M. K. Tags: COVID-19 Letter Source Type: research

Response to: Correspondence on "Cerebral aneurysms: Germany-wide real-world outcome data of endovascular or neurosurgical treatment from 2007 to 2019" by Cole
In this study, missing information includes aneurysm location, aneurysm size, why a treatment was chosen, whether a pathology was a comorbidity or a complication, if there was an external ventricular drain, and all the details regarding the aneurysmal disease process. In short, we do not know if these cohorts are comparable." We fully agree with this major limitation of our study. When conducting the study we were aware of this limitation and included two paragraphs describing details of it in the Limitations section at the end of the discussion. Furthermore, we decided against sophisticated matching or weighting methods b...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Kaier, K., Haverkamp, C., Meckel, S. Tags: Letter Source Type: research

Correspondence on 'Cerebral aneurysms: Germany-wide real-world outcome data of endovascular or neurosurgical treatment from 2007 to 2019 by Haverkamp et al
In this study, missing information includes aneurysm location, aneurysm size, why a treatment was chosen, whether a pathology was a comorbidity or... (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Cole, T. S. Tags: Letter Source Type: research

Stereotactic-guided direct orbital puncture for treatment of orbital arteriovenous fistula
The patient presented with left-sided chemosis, exophthalmos, and progressive visual loss. Cerebral angiography ed a left orbital arteriovenous malformation and an associated hematoma, with the point of fistulation between the left ophthalmic artery and the anterior section of the inferior ophthalmic vein, with retrograde flow through the superior ophthalmic vein. Transvenous embolization through the anterior facial and angular veins was unsuccessful, with residual shunting. Stereotactic-guided direct venous puncture and Onyx embolization was subsequently performed in the hybrid operating room (OR) to cure the fistula. A s...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Robledo, A., Frank, T. S., Karas, P. J., Shaltoni, H., O'Leary, S., Darling, R., Kan, P. Tags: Technical video Source Type: research

Now that the door is open: an update on ischemic stroke pharmacotherapeutics for the neurointerventionalist
The last 10 years have seen a major shift in management of large vessel ischemic stroke with changes towards ever-expanding use of reperfusion therapies (intravenous thrombolysis and mechanical thrombectomy). These strategies ‘open the door’ to acute therapeutics for ischemic tissue, and we should investigate novel therapeutic approaches to enhance survival of recently reperfused brain. Key insights into new approaches have been provided through translational research models and preclinical paradigms, and through detailed research on ischemic mechanisms. Additional recent clinical trials offer exciting salvos i...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Fraser, J. F., Pahwa, S., Maniskas, M., Michas, C., Martinez, M., Pennypacker, K. R., Dornbos, D. Tags: Vascular neurology Source Type: research

Symptomatic non-stenotic carotid disease: current challenges and opportunities for diagnosis and treatment
Symptomatic non-stenotic carotid plaques (SyNC) are an under-researched and under-recognized source of stroke. Various imaging markers of non-stenotic carotid plaques that are associated with stroke risk have been identified, but these causal relationships need to be confirmed in additional prospective studies. Currently, there exists neither a standardized SyNC definition nor a dedicated set of imaging protocols, although researchers have started to address these shortcomings. Moreover, many neuroradiologists are still unaware of the condition, and hence do not comment on high-risk plaque features other than stenosis in t...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Ospel, J. M., Kappelhof, M., Ganesh, A., Kallmes, D. F., Brinjikji, W., Goyal, M. Tags: Vascular neurology Source Type: research

Robotically assisted deployment of flow diverter stents for the treatment of cerebral and cervical aneurysms
Conclusion Robot-assisted flow diverter stent deployment using the CorPath GRX platform is feasible and appears to be safe. Larger, in-depth studies of the technique’s safety and benefits are now warranted. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Chivot, C., Bouzerar, R., Peltier, J., Lefranc, M., Yzet, T. Tags: New devices New devices and techniques Source Type: research

Evaluation of effectiveness and safety of the CorPath GRX robotic system in endovascular embolization procedures of cerebral aneurysms
Conclusions This first-of-its-kind robotic-assisted neurovascular trial demonstrates the effectiveness and safety of the CorPath GRX System for endovascular embolization of cerebral aneurysm procedures. Trial registration number NCT04236856 (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Mendes Pereira, V., Rice, H., De Villiers, L., Sourour, N., Clarencon, F., Spears, J., Tomasello, A., Hernandez, D., Cancelliere, N. M., Liu, X. Y. E., Nicholson, P., Costalat, V., Gascou, G., Mordasini, P., Gralla, J., Martinez-Galdamez, M., Galvan Ferna Tags: Open access, New devices New devices and techniques Source Type: research

Advancements in super-selective catheterization and drug selection for intra-arterial chemotherapy for retinoblastoma: a 15-year evolution
Conclusions The overall rate of successful catheterization and IAC started high and has improved over 15 years, and catheterization-related complications are rare. There has been a significant trend towards triple chemotherapy over time. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Kocharian, G., Gobin, Y. P., Kharas, N., Knopman, J., Francis, J. H., Abramson, D. H. Tags: New devices New devices and techniques Source Type: research

Evaluation of predictive models of aneurysm focal growth and bleb development using machine learning techniques
Conclusions Models trained with cross-sectional data can identify aneurysms prone to future focalized growth with good accuracy. These models could potentially be used as early indicators of future risk in clinical practice. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Hadad, S., Mut, F., Slawski, M., Robertson, A. M., Cebral, J. R. Tags: Hemorrhagic stroke Source Type: research

Diffusion-weighted imaging lesions after intracranial aneurysm treatment with Pipeline Flex and Pipeline Flex with Shield technology: a retrospective cohort analysis
Conclusion There was no significant difference in the incidence of perioperative DWI+ lesions between patients with an aneurysm treated with PED Flex and PED Shield. Larger cohorts are likely needed to demonstrate differences between the devices. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Cortez, G. M., Benalia, V. H. C., Sauvageau, E., Aghaebrahim, A., Pederson, J. M., Hanel, R. A. Tags: Hemorrhagic stroke Source Type: research

Pipeline embolization device versus Atlas stent assisted coiling for intracranial aneurysm treatment: a retrospective, propensity score matched study with a focus on midterm outcomes and hospital costs
Conclusion In this PSM study, midterm outcomes of the PED and Atlas SAC in the treatment of ICA aneurysms were similar. However, SAC required a longer operation time, and the PED may increase the economic cost of inpatients in Beijing, China. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Wang, C., Dong, L., Liu, J., Zhang, Y., Wang, K., Liu, P., Yang, X., Lv, M., Zhang, Y. Tags: Hemorrhagic stroke Source Type: research

Flow diversion for basilar quadrifurcation aneurysms
Conclusion Flow diversion may be a safe and effective option to treat basilar quadrifurcation aneurysms. Previously treated basilar quadrifurcation aneurysms with recurrence or residual lesion may benefit from additional treatment with an FDD. Further prospective studies should be directed toward validating these findings. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Srinivasan, V. M., Jubran, J. H., Stonnington, H. O., Catapano, J. S., Scherschinski, L., Hendricks, B. K., Winkler, E. A., Rudy, R. F., Nguyen, B. A., Dabrowski, S. J., Jadhav, A. P., Ducruet, A. F., Albuquerque, F. C. Tags: Hemorrhagic stroke Source Type: research

Cerebral aneurysms: Germany-wide real-world outcome data of endovascular or neurosurgical treatment from 2007 to 2019
Conclusions In German clinical practice, we observed higher rates of functional independence and lower rates of poor outcomes at discharge with equal mortality for EVT. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Haverkamp, C., Kaier, K., Shah, M., von zur Mühlen, C., Beck, J., Urbach, H., Meckel, S. Tags: Open access, Hemorrhagic stroke Source Type: research

Systemic THrombolysis Randomization IN Endovascular Stroke Therapy (SHRINE) Collaboration: a patient-level pooled analysis of the SKIP and DEVT Trials
Conclusions The cumulative data of these two recent Asian trials failed to unequivocally demonstrate the non-inferiority of EVT alone over combined IVT+EVT. However, our study suggests a potential role for more individualized decision-making. Specifically, Asian patients with stroke onset to EVT longer than 180 min, as well as those with intracranial ICA occlusions and those with atrial fibrillation might have better outcomes with EVT alone than with combined IVT+EVT. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Nogueira, R. G., Kimura, K., Matsumaru, Y., Suzuki, K., Qiu, Z., Zi, W., Moran, T. P., Li, F., Sang, H., Luo, W., Liu, S., Yuan, J., Song, J., Huang, J., Takeuchi, M., Morimoto, M., Otsuka, T., Yang, Q. Tags: Ischemic stroke Source Type: research