Autism Spectrum Disorders: Challenges and perspectives
(Source: Journal of Neurobiology)
Source: Journal of Neurobiology - March 1, 2018 Category: Neurology Authors: Alysson Renato Muotri Tags: Editorial Source Type: research
Adult spinal opioid receptor μ1 expression after incision is altered by early life repetitive tactile and noxious procedures in rats
ABSTRACT
Clinical and experimental data suggests that noxious stimulation at critical stages of development results in long‐term changes on nociceptive processing in later life. Here, we use an established, well‐documented rat model of repetitive noxious procedures closely mimicking the clinical situation in the NICU. In order to understand molecular changes underlying the long‐term consequences of repetitive stimulation of the developing nociceptive system the present study aims to analyze the presence of the µ‐opioid‐receptor‐1 (OPRM1). Neonatal rats received either four needle pricks per day in the left hin...
Source: Journal of Neurobiology - February 28, 2018 Category: Neurology Authors: Nynke J van den Hoogen, Roel RI van Reij, Jacob Patijn, Dick Tibboel, Elbert AJ Joosten Tags: Research Article Source Type: research
Genetic variations on SETD5 underlying autistic conditions
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - February 27, 2018 Category: Neurology Authors: Isabella R. Fernandes, Ana C. P. Cruz, Adriano Ferrasa, Dylan Phan, Roberto H. Herai, Alysson R. Muotri Tags: Review Article Source Type: research
Adult spinal opioid receptor µ1 expression after incision is altered by early life repetitive tactile and noxious procedures in rats
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - February 23, 2018 Category: Neurology Authors: Nynke J van den Hoogen, Roel RI van Reij, Jacob Patijn, Dick Tibboel, Elbert AJ Joosten Tags: Research Article Source Type: research
Searching for the gut microbial contributing factors to social behavior in rodent models of autism spectrum disorder
ABSTRACT
Social impairment is one of the major symptoms in multiple psychiatric disorders, including autism spectrum disorder (ASD). Accumulated studies indicate a crucial role for the gut microbiota in social development, but these mechanisms remain unclear. This review focuses on two strategies adopted to elucidate the complicated relationship between gut bacteria and host social behavior. In a top‐down approach, researchers have attempted to correlate behavioral abnormalities with altered gut microbial profiles in rodent models of ASD, including BTBR mice, maternal immune activation (MIA), maternal valproic acid (VPA)...
Source: Journal of Neurobiology - February 20, 2018 Category: Neurology Authors: Brittany D. Needham, Weiyi Tang, Wei ‐Li Wu Tags: Review Article Source Type: research
Introduction to the special issue on membrane trafficking in neurons
(Source: Journal of Neurobiology)
Source: Journal of Neurobiology - February 17, 2018 Category: Neurology Authors: Huaye Zhang, Bettina Winckler, Qian Cai Tags: Editorial Source Type: research
Issue Information
(Source: Journal of Neurobiology)
Source: Journal of Neurobiology - February 17, 2018 Category: Neurology Tags: Issue Information Source Type: research
Cover Image
Cover: The cover, by Huaye Zhang et al., is based on the Editorial Introduction to the Special Issue on Membrane Trafficking in Neurons, DOI: 10.1002/dneu.22573. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - February 17, 2018 Category: Neurology Authors: Huaye Zhang, Bettina Winckler, Qian Cai Tags: Cover Image Source Type: research
Developmental and sex differences in tetramethylenedisulfotetramine (TMDT) ‐induced syndrome in rats
In conclusion, the youngest age group represents the most vulnerable population to the TMDT‐induced toxidrome. Females appear to be more vulnerable than males. TMDT exposure promotes seizure spread and progression in survivors. These findings will help to establish sex‐ and age‐specific treatment strategies for TMDT‐exposed individuals. This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - February 7, 2018 Category: Neurology Authors: Marcela Laukov á, Jana Velíšková, Libor Velíšek, Michael P. Shakarjian Tags: Research Article Source Type: research
Searching for the gut microbial contributing factors to social behavior in rodent models
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - February 1, 2018 Category: Neurology Authors: Brittany D. Needham, Weiyi Tang, Wei ‐Li Wu Tags: Review Article Source Type: research
Microglial interactions with the neurovascular system in physiology and pathology
ABSTRACT
Microglia as immune cells of the central nervous system (CNS) play significant roles not only in pathology but also in physiology, such as shaping of the CNS during development and its proper maintenance in maturity. Emerging research is showing a close association between microglia and the neurovasculature that is critical for brain energy supply. In this review, we summarize the current literature on microglial interaction with the vascular system in the normal and diseased brain. First, we highlight data that indicate interesting potential involvement of microglia in developmental angiogenesis. Then we discuss ...
Source: Journal of Neurobiology - February 1, 2018 Category: Neurology Authors: Xiaoliang Zhao, Ukpong B. Eyo, Madhuvika Murugan, Long ‐Jun Wu Tags: Review Article Source Type: research
Targeted deletion of RIC8A in mouse neural precursor cells interferes with the development of the brain, eyes and muscles
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - January 30, 2018 Category: Neurology Authors: Keiu Kask, Laura Tikker, Katrin Ruisu, Sirje Lulla, Eva ‐Maria Oja, Riho Meier, Raivo Raid, Teet Velling, Tambet Tõnissoo, Margus Pooga Tags: Research Article Source Type: research
Folate action in nervous system development and disease
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - January 30, 2018 Category: Neurology Authors: Olga A. Balashova, Olesya Visina, Laura N. Borodinsky Tags: Review Article Source Type: research
Introduction to the special issue on myelin plasticity in the central nervous system
(Source: Journal of Neurobiology)
Source: Journal of Neurobiology - January 18, 2018 Category: Neurology Authors: Patrizia Casaccia, Gabriel Corfas Tags: Editorial Source Type: research
Issue Information
(Source: Journal of Neurobiology)
Source: Journal of Neurobiology - January 18, 2018 Category: Neurology Tags: Issue Information Source Type: research
