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A Combined Power M-mode and Single Gate Transcranial Doppler Ultrasound Microemboli Signal Criteria for Improving Emboli Detection and ReliabilityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Single gate transcranial Doppler spectrogram (sgTCD) has a high variability in the detection of microembolic signals (MES), Adding Power M-mode Doppler (PMD) information may improve MES detection. Our study's aim is to derive combined PMD/sgTCD microemboli criteria to overcome this limitation. Patients with symptomatic carotid disease were prospectively enrolled within 24 h of symptom onset underwent 1 hour TCD emboli monitoring. We reviewed disparity between PMD MES criteria and sgTCD MES criteria. We compared combined PMD/sgTCD criteria to sgTCD alone criteria by measuring the intraclass correlation coefficient (ICC). Of...
Source: Journal of Neuroimaging - November 14, 2009 Category: Radiology Authors: Youngbin Choi, Maher Saqqur, Talip Asil, Albert Jin, Eileen Stewart, Caroline Stephenson, Mohamad Ibrahim, Jayanta Roy, Jean-Martin Boulanger, Shelagh Coutts, Firosh Khan, Andrew M Demchuk Source Type: journals

Vasomotor Reactivity Is Similarly Impaired in Patients with Alzheimer's Disease and Patients with Amyloid HemorrhageEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cerebral amyloid angiopathy (CAA) might alter cerebral hemodynamics. Impairment of vasomotor reactivity may constitute a biomarker of amyloid angiopathy and therefore it may be useful to distinguish disorders with CAA from other conditions. The aim of this study was to assess the vasomotor reactivity in two conditions characterized by CAA: Alzheimer's disease and amyloid hemorrhage. We assessed the vasomotor using transcranial Doppler and the breath-holding method. Responses obtained in controls were higher than in patients with Alzheimer's or with antecedent of amyloid hemorrhage while there was no statistical difference ...
Source: Journal of Neuroimaging - November 13, 2009 Category: Radiology Authors: Manuel Menendez-Gonzalez, Jorge Garcia-Garcia, Sergio Calleja, Jose Rojo, Renee Ribacoba Source Type: journals

Intraplaque Hemorrhage in Symptomatic Intracranial Atherosclerotic DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present the use of high-resolution magnetic resonance imaging for the detection of intraplaque hemorrhage in the intracranial arteries. High-resolution 3 Tesla MRDTI was performed using T1-weighted scans with an inversion pulse to null the signal from blood. Abnormal intraplaque T1 signal compatible with hemorrhage or blood products was defined as equal to or higher than 150% of T1 signal of adjacent muscle. The symptomatic middle cerebral artery demonstrated intraplaque signal higher than 150% of the muscle signal in two central slices, consistent with the imaging characteristics of intraplaque hemorrhage demonstrated ...
Source: Journal of Neuroimaging - November 11, 2009 Category: Radiology Authors: Tanya N. Turan, Leonardo Bonilha, Paul S. Morgan, Robert J. Adams, Marc I. Chimowitz Source Type: journals

2010 ASN AbstractsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: VBD can enlarge to significant dimensions, producing compressive symptoms in the brainstem, as well as thrombosis and ischemic strokes. SACE of the dolichoectasia can be effective for the vessel reconstruction, to prevent progression of the dilatation, and other potential clinical events. 3. Three Case Reports of Multiple Carotid and/or Vertebral Artery Dissections in Female Mei Lu, Heather Gornik, Esteban Cheng Ching, Vikram Kashyap, Rishi Gupta Cleveland Clinic Foundation, Cleveland, OH 44195, United States Introduction: Multiple carotid and/or vertebral artery dissections are rare. However, patients with mul...
Source: Journal of Neuroimaging - November 11, 2009 Category: Radiology Source Type: journals

Comparison of Partial (.6 mg/kg) versus Full-Dose (.9 mg/kg) Intravenous Recombinant Tissue Plasminogen Activator Followed by Endovascular Treatment for Acute Ischemic Stroke: A Meta-AnalysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the treatment of acute ischemic stroke, intravenous (IV) recombinant tissue plasminogen (rt-PA) and intraarterial (IA) interventions are often combined. However, the optimal dose of IV rt-PA preceding endovascular treatment has not been established. Studies that used combined IV and IA thrombolysis were identified from a search of the MEDLINE, PubMed, and Cochrane databases. We compared the rates of angiographic recanalization, symptomatic intracerebral hemorrhage (sICH), and favorable functional outcome between patients who had been treated with .6 mg/kg IV rt-PA and those who had received .9 mg/kg rt-PA. Eleven studie...
Source: Journal of Neuroimaging - November 10, 2009 Category: Radiology Authors: Alexandros L. Georgiadis, Muhammad Zeeshan Memon, Qaisar A. Shah, Gabriela Vazquez, M. Fareed K. Suri, Kamakshi Lakshminarayan, Adnan I. Qureshi Source Type: journals

Ultrasonographic and Perioperative Macroscopic Findings in Acute Carotid Artery OcclusionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Acute ischemic stroke (AIS) may occur both in the acute and chronic internal carotid artery occlusion (ICAo). Thus, it is important to assess the ICAo character when considering the recanalization method. The aim was to assess the agreement between the ultrasonographic (US) and perioperative macroscopic (PM) finding in AIS patients with acute ICAo, undergoing an emergent carotid endarterectomy. In a retrospective, hospital-based study, the set consisted of 47 patients (36 males; age 49-79, mean 63.7 ± 8.5 years). ICAo character was classified as an acute thromboembolus either isolated or in combination with atheroscleroti...
Source: Journal of Neuroimaging - November 5, 2009 Category: Radiology Authors: Roman Herzig, David [Scaron]koloudík, Michal Král, Daniel [Scaron]aňák, Martin Roubec, Ondřej [Scaron]koda, Petr Bachleda, Petr Utíkal, Pavel Havránek, Tomá[scaron] Hrbáč, Milan Fučík, Jana Dvořáčková, J Source Type: journals

Detection of the Siphon Internal Carotid Artery Stenosis: Transcranial Doppler versus Digital Subtraction AngiographyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Transcranial Doppler (TCD) is widely applied to evaluate the intracranial large artery stenosis. We aimed to evaluate the accuracy of TCD in detecting siphon internal carotid artery (SICA) stenosis against digital subtraction angiography (DSA). A total of 145 patients with TCD and DSA performed were recruited. The SICA and other intracranial arteries were evaluated through transorbital and transtemporal acoustic window by TCD. We defined the best cutoff value for significant SICA stenosis by receiver-operating characteristic (ROC) curve analyses and calculated the sensitivity, specificity, and positive and negative predict...
Source: Journal of Neuroimaging - November 4, 2009 Category: Radiology Authors: Yong You, Qing Hao, Thomas Leung, Vincent Mok, Xiangyan Chen, Alex Lau, Howan Leung, Ka Sing Wong Source Type: journals

Detection of Carotid Artery Plaque Ulceration Using 3-Dimensional UltrasoundEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Three-dimensional (3D) ultrasound imaging is a new technique that maximizes the information and image quality of traditional 2-dimensional (2D) B-mode scanning. The aim of this study was to evaluate the ability of the 3D ultrasound technique to characterize ulcerated atherosclerotic carotid plaque. Using conventional 2D ultrasound, we examined 284 carotid arteries from 142 consecutive patients (101 men and 41 women; average age, 64 years). Eighty-two carotid arteries were symptomatic with atherosclerotic plaque causing 50-99% stenosis. In 62 arteries, the atherosclerotic plaques were visualized completely and were further ...
Source: Journal of Neuroimaging - November 4, 2009 Category: Radiology Authors: John Heliopoulos, Konstantinos Vadikolias, Charitomeni Piperidou, Panayiotis Mitsias Source Type: journals

Evaluation of Postoperative Status after Clipping Surgery in Patients with Cerebral Aneurysm on 3-Dimensional-CT Angiography with Elimination of ClipsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The use of 3-dimensional computed tomography angiography (3D-CTA) for clipped aneurysms is limited. Usefulness of 3D-CTA with elimination of bone and clips was evaluated in patients with clipped cerebral aneurysms. Forty-three clipped cerebral aneurysms were included. As review of digital subtraction angiography after surgery is the current gold standard, the presence or absence of remnant necks on 3D-CTA with elimination of bone and clips was compared with that on conventional CTA, using receiver operating characteristic analysis (5, definitely absent; 1, definitely present). In the ROC analysis, the Az (.949) in CTA with...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: Noriaki Tomura, Ikuo Sakuma, Takahiro Otani, Toshiaki Nisii, Makoto Sugawara, Makoto Koga, Satoshi Takahashi, Toshiharu Yanagisawa, Kazuo Mizoi Source Type: journals

Partial Intra-Aortic Occlusion Improves Perfusion Deficits and Infarct Size Following Focal Cerebral IschemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined the effects of aortic occlusion on infarct volume, expression and activation of matrix metalloprotease-9, and hemorrhagic transformation with or without treatment with tPA. We then examined the effects of aortic occlusion on perfusion deficits following embolic occlusion. Results showed that partial aortic occlusion significantly reduces brain infarction volume with or without treatment with tPA after focal ischemia, but does not increase risk for hemorrhagic transformation or matrix metalloprotease-9 expression and activation. Partial intra-aortic occlusion also reduces perfusion deficits after focal cerebral ...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: Raza Noor, Chen Xu Wang, Kathryn Todd, Cameron Elliott, Joyce Wahr, Ashfaq Shuaib Source Type: journals

Effect of Hyper- and Hypocapnia on Cerebral Arterial Compliance in Normal SubjectsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Changes in partial pressure of carbon dioxide (PaCO2) are associated with a decrease in cerebral blood flow (CBF) during hypocapnia and an increase in CBF during hypercapnia. However, the effects of changes in PaCO2 on cerebral arterial compliance (Ca) are unknown. We assessed the changes in Ca in 20 normal subjects using monitoring of arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV). Cerebral arterial blood volume (CaBV) was extracted from CBFV. Ca was defined as the ratio between the pulse amplitudes of CaBV (AMPCaBV) and ABP (AMPABP). All parameters were recorded during normo-, hyper-, and hypocapni...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: Emmanuel Carrera, Dong-Joo Kim, Gianluca Castellani, Christian Zweifel, Peter Smielewski, John D. Pickard, Marek Czosnyka Source Type: journals

Cerebral Microbleeds Are Uncommon in Ischemic Stroke Associated with Nonvalvular Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study examines the prevalence of cerebral microbleeds (MBs) in stroke patients with NVAF. A total of 132 consecutive ischemic stroke patients with NVAF admitted to our Stroke Unit were recruited if complete magnetic resonance (MR) imaging studies including T2* imaging had been performed within less than 72 hours. National Institutes of Health Stroke Scale scores were documented and cerebrovascular risk factors were monitored. Among 132 patients (mean age 74.1 ± 9.8 years), only 9 (6.8%) had MBs (mean number 6.2) as detected on T2* MR images. No statistically significant differences between patients without versus wit...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: Anastasios Chatzikonstantinou, Olaf Willmann, Kristina Szabo, Michael G. Hennerici Source Type: journals

Acute Multiple Sclerosis Lesion: Conversion of Restricted Diffusion Due to Vasogenic EdemaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of active relapsing-remitting MS with two new symptomatic contrast-enhancing lesions. The lesions had reduced diffusion on the ADC map in the early acute phase of MS exacerbation. The reduced ADC signal was subsequently "converted" to increased ADC signal that coincided with the development of profound peripheral vasogenic edema seen on T2-weighted images. To our knowledge, this is the first serial MRI study describing decreased ADC signal in the early acute phase of contrast-enhancing MS lesion. The implications of decreased diffusion in the acute phase of MS lesions for the disease pathogenesis are discu...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: Konstantin E. Balashov, Latt Latt Aung, Suhayl Dhib-Jalbut, Irwin A. Keller Source Type: journals

White Matter Lesion Load Increases the Risk of Low CSF Aβ42 in Apolipoprotein E-ɛ4 Carriers Attending a Memory ClinicEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
White matter lesions (WMLs) are age-related manifestations of ischemic cerebrovascular disease and increase the risk for Alzheimer's disease (AD). The apolipoprotein E (ApoE) ɛ4 allele is a risk factor for late onset AD and has been related to low cerebrospinal fluid (CSF) A[beta]42 levels and to cerebrovascular disease. The present study analyzed the relationship between WMLs, ApoE-ɛ4 genotype, and low CSF A[beta]42. A total of 235 memory clinic attenders were stratified in 3 groups according to WML load. WMLs were rated on axial T2 magnetic resonance imaging images. Group 1 had no or only small amounts of p...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: Vidar Stenset, Dag Hofoss, Lisbeth Johnsen, Audun Elnaes Berstad, Anne Negaard, Anders Skinningsrud, Leif Gjerstad, Tormod Fladby Source Type: journals

Three-Dimensional Digital Subtraction Angiography in Evaluation of Vertebro-Basilar Artery Dissections: Comparison with 2D DSAEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to clarify characteristic findings on three-dimensional (3D) digital subtraction angiography (DSA), and to investigate diagnostic usefulness of 3D DSA in vertebro-basilar dissections (VBD). In 25 consecutive patients with VBD, two-dimensional (2D) DSA, and 3D DSA findings were evaluated by a scoring system. The effects of 3D DSA results on diagnosis were scored in comparison with 2D DSA results. A proximal stenosis, a distal stenosis, a bleb, and a relationship between the posterior inferior cerebellar artery and the dissection were significantly better visualized in 3D DSA than those in 2D DS...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: Takatoshi Sorimachi, Kenji Suzuki, Osamu Sasaki, Tetsuo Koike, Yukihiko Fujii Source Type: journals

Complementary Image Analysis of Diffusion Tensor Imaging and 3-Dimensional T1-Weighted Imaging: White Matter Analysis in Amyotrophic Lateral SclerosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In order to obtain detailed information on disease-associated changes in the integrity of cerebral white matter (WM), complementary image analysis (CIA) was applied to patients with amyotrophic lateral sclerosis (ALS) and controls. Both diffusion tensor imaging and T1-weighted 3-dimensional data were analyzed with respect to WM microstructure and T1 signal intensity alterations, respectively, in a sample of 19 ALS patients. Covariate information was added in the form of clinical parameters. All results were obtained in one common analysis software environment (Tensor Imaging and Fiber Tracking). Complementary analysis and ...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: Hans-Peter Müller, Dorothée Lulé, Alexander Unrath, Albert C. Ludolph, Axel Riecker, Jan Kassubek Source Type: journals

Giant Tumefactive Perivascular Spaces Manifesting as Chorea BilaterallyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the first MR imaging description of a case of giant tumefactive (PVSs) manifesting as chorea bilaterally. J Neuroimaging 2009;XX:1[ndash]3. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: T. Thomas Zacharia Source Type: journals

Brain MRI Lesion Load at 1.5T and 3T versus Clinical Status in Multiple SclerosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To assess correlation between brain lesions and clinical status with 1.5T and 3T magnetic resonance imaging (MRI). Brain MRI fluid-attenuated inversion-recovery (FLAIR) sequences were performed in 32 multiple sclerosis (MS) patients. Expanded Disability Status Scale score (mean ± standard deviation) was 2 ± 2.0 (range 0-8), disease duration 9.3 ± 8.0 (range .8-29) years. FLAIR lesion volume (FLLV) at 3T was higher than at 1.5T (P= .01). Correlation between 1.5T FLLV was poor, while 3T FLAIR lesion volume correlated moderately and significantly (rs= .39, P= .03). When controlling for age and depression, correlations betw...
Source: Journal of Neuroimaging - November 3, 2009 Category: Radiology Authors: James M. Stankiewicz, Bonnie I. Glanz, Brian C. Healy, Ashish Arora, Mohit Neema, Ralph H.B. Benedict, Zachary D. Guss, Shahamat Tauhid, Guy J. Buckle, Maria K. Houtchens, Samia J. Khoury, Howard L. Weiner, Charles R.G. Guttmann, Rohit Bakshi Source Type: journals

A Multicenter Analysis of "Time to Microcatheter" for Endovascular Therapy in Acute Ischemic StrokeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
At present, no time recommendation for initiation of endovascular treatment in acute ischemic stroke is available. A multicenter analysis was designed to identify variables that prolong "time to microcatheter," defined as the time interval from computed tomographic scan to microcatheter placement in the cerebral circulation. Consecutive acute ischemic stroke patients from 3 academic stroke centers were included. Analysis of covariance was used to evaluate different variables that prolong "time to microcatheter." Ninety-one patients underwent emergent endovascular treatment for acute ischemic stroke. Mean "time to microcath...
Source: Journal of Neuroimaging - October 7, 2009 Category: Radiology Authors: Jefferson T. Miley, Muhammad Zeeshan Memon, Haitham M. Hussein, Douglas A. Valenta, M. Fareed K. Suri, Gabriela Vazquez, Adnan I. Qureshi Source Type: journals

Thromboembolism and Rebleeding Paradox in Stent-Assisted Embolization for Intracranial AneurysmsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
J Neuroimaging 2009;XX:1[ndash]2. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - September 16, 2009 Category: Radiology Authors: Ramachandra P. Tummula, Adnan I. Qureshi Source Type: journals

Investigating Agenesis of the Corpus Callosum Using Functional MRI: A Study Examining Interhemispheric Coordination of Motor ControlEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report fMRI findings in 3 asymptomatic cases of agenesis of the corpus callosum, the largest white matter bundle in the brain, which is responsible for interhemispheric transfer of information. Sensory information was presented to 1 hemisphere, and the patients had to generate a motor response governed by the contralateral hemisphere. Enhanced ipsilateral motor pathways have been suggested as a compensation method for people with agenesis of the corpus callosums; our functional magnetic resonance imaging data did not support this theory. J Neuroimaging 2009;XX:1[ndash]4. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - September 15, 2009 Category: Radiology Authors: Cheemun Lum, Mary Pat McAndrews, Andrei I. Holodny, Kathleen A. McManus, Adrian Crawley, Santanu Chakraborty, David J. Mikulis Source Type: journals

Endovascular Treatment of Atypical Posterior Circulation Aneurysms: Technical Results and Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report our technical success and complication rates in treating posterior circulation aneurysms at sites other than the basilar apex, superior cerebellar artery origin, or the posterior inferior cerebellar artery origin via endovascular embolization or sacrifice. We retrospectively reviewed case records for patients undergoing coil embolization of atypical posterior circulation aneurysms from January 2003 to December 2007. Thirty-two aneurysms in 32 patients were treated. Twenty-one patients (65%) presented with a subarachnoid hemorrhage. Twenty-two aneurysms were treated with coiling alone, 9 with stent-assisted coilin...
Source: Journal of Neuroimaging - September 14, 2009 Category: Radiology Authors: Brian T. Jankowitz, Aitziber Aleu, Ridwan Lin, Dean Kostov, Ajith J. Thomas, Rishi Gupta, Nirav Vora, Kim Seong R, Narendra Panapitiya, Tudor Jovin, Michael Horowitz Source Type: journals

Is Transcranial Doppler Ultrasound Undervalued for Detection of Intracranial Internal Carotid Artery Stenosis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
J Neuroimaging 2009;XX:1[ndash]2. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - September 11, 2009 Category: Radiology Authors: Gustavo J. Rodriguez, M. Fareed K. Suri, Alexander Razumovsky, Adnan I. Qureshi Source Type: journals

Isolated and Reversible Lesions of the Corpus Callosum: A Distinct EntityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Reversible Splenial Lesion Syndrome represents a distinct clinicoradiological syndrome, associated with several disorders, including infection, high altitude cerebral edema, antiepileptic drug withdrawal, and severe metabolic disturbances (hypoglycemia and hypernatremia). Clinical presentation is nonspecific, most frequently as an encephalopathy or encephalitis. Outcome is favorable in most patients unless there is a severe underlying disorder. Magnetic resonance imaging findings are restricted to the splenium and consist of a nonenhancing oval lesion, hyperintense on T2-weighted images, including FLAIR. Findings on di...
Source: Journal of Neuroimaging - September 10, 2009 Category: Radiology Authors: Juan Carlos Garcia-Monco, Amaia Martínez, Ana Pinedo Brochado, Ibone Saralegui, Alberto Cabrera, Marian Gomez Beldarrain Source Type: journals

Coil Embolization of Intracranial Dissecting Vertebral Artery Aneurysms with Subclavian StealEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report 3 patients with asymptomatic subclavian steal phenomenon with retrograde blood flow in the vertebral artery who presented with subarachnoid hemorrhage due to dissecting aneurysms of the involved vertebral artery. The association of subclavian steal phenomenon complicated by subarachnoid hemorrhage due to dissecting vertebral aneurysms has not been previously described. J Neuroimaging 2009;XX:1[ndash]3. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - September 10, 2009 Category: Radiology Authors: Dorothea Strozyk, Brijesh P. Mehta, Philip M. Meyers, Raul G. Nogueira Source Type: journals

Wallerian Degeneration in Lateral Cervical Spinal Cord Detected with Diffusion Tensor Imaging in Four Chronic Stroke PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study provides preliminary evidence that DTI at 1.5 T can be used for identification and quantification of WD in the lateral cervical spinal cord in stroke patients. This may prove useful for prognosis of motor outcome after stroke. J Neuroimaging 2008;XX:1[ndash]5. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - September 1, 2009 Category: Radiology Authors: Påvel G. Lindberg, Djamel Bensmail, Bernard Bussel, Marc A. Maier, Antoine Feydy Source Type: journals

Intraaneurysmal Neuroform Stent Implantation with Compartmental Dual Microcatheter Coil Embolization: Technical Case ReportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A complex middle cerebral artery (MCA) aneurysm failed surgical clipping. The aneurysm morphology was characterized by a broad neck with incorporated diminutive branch vasculature and mural calcification. To preserve flow within incorporated branch vessels, coil embolization with intraaneurysmal Neuroform stent implantation was achieved with a novel technique. A 52-year-old female presented with an unruptured complex configuration right MCA bifurcation aneurysm. Endovascular coil embolization with intraaneurysmal stent deployment and compartmental dual microcatheter placement was performed a month after failed surgical cli...
Source: Journal of Neuroimaging - August 31, 2009 Category: Radiology Authors: Ajeet D. Gordhan Source Type: journals

Hemodynamic Changes Following Wingspan Stent Placement—A Quantitative Magnetic Resonance Angiography StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Quantitative magnetic resonance angiography (QMRA) is a noninvasive imaging modality that provides anatomic and physiologic measurements of arteries. We used QMRA to assess hemodynamic changes following Wingspan stent placement for intracranial stenosis. We reviewed patients treated with Wingspan stents for intracranial stenosis who had baseline and follow-up QMRA data. We compared volumetric flow rates (VFRs) (mL/minute) pre- and poststenting using paired t-tests. P < .05 was considered significant. Among 9 patients (mean age 65.8 years, mean 71% degree of stenosis), lesions were located in the supraclinoid internal carot...
Source: Journal of Neuroimaging - August 28, 2009 Category: Radiology Authors: Shyam Prabhakaran, Kalani R. Wells, Miral D. Jhaveri, Demetrius K. Lopes Source Type: journals

Neurovascular Coupling and Cerebral Autoregulation in Patients with Stenosis of the Posterior Cerebral ArteryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study examined if stenotic disease affects both mechanisms in the posterior cerebral artery. Ten patients with altogether 13 stenosed ([ge]50%) posterior cerebral artery (PCA) sides were studied. In addition, 6 control persons without a PCA stenosis were examined. Cerebral blood flow velocity was assessed from both PCAs with transcranial Doppler sonography; blood pressure was measured noninvasively via fingerplethysmography. Neurovascular coupling was assessed by a control system approach using a standard visual stimulation paradigm. Cerebral autoregulation dynamics were measured from spontaneous oscillations of blood...
Source: Journal of Neuroimaging - August 27, 2009 Category: Radiology Authors: Carsten Fritzsch, Bernhard Rosengarten, Brigitte Guschlbauer, Cornelius Weiller, Andreas Hetzel, Matthias Reinhard Source Type: journals

Endovascular Treatment of Aneurysms Associated with Fenestrated A1 Segment of Anterior Cerebral Artery: Report of Two CasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fenestration in A1 segment of anterior cerebral artery is a rare entity. Treatment of aneurysms derived from a fenestrated artery may be more challenging because the fenestrations provide specific difficulties. A thorough radiologic work-up driven by high clinical suspicion is needed. Endovascular treatment, although it has been tried only once,7 appears to be the treatment of choice. We successfully treated 2 cases using endovascular techniques and can conclude that endovascular treatment is a safe and effective treatment of aneurysms associated with this rare variation in the A1 segment of ACA. J Neuroimaging 2009;XX:1[n...
Source: Journal of Neuroimaging - August 14, 2009 Category: Radiology Authors: Michael Mantatzis, Osman Kizilkilic, Sait Albayram, Naci Kocer, Civan Islak Source Type: journals

Perfusion CT in Hyperacute Cerebral Hemorrhage Within 3 Hours after Symptom Onset: Is There an Early Perihemorrhagic Penumbra?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the recent years numerous studies have been undertaken to study cerebral perfusion in the surrounding of intracerebral hemorrhage, addressing the question of whether there is a secondary ischemic damage. Most of these studies found a reduced perfusion adjacent to the hematoma. However, the meaning of these findings remains controversial. We used perfusion computed tomography in 17 patients to study time to peak, cerebral blood flow, and cerebral blood volume as markers of the perihemorrhagic perfusion within 3 hours after symptom onset to search for an early difference between the extent of edema and reduced perfusion. ...
Source: Journal of Neuroimaging - August 13, 2009 Category: Radiology Authors: Christian Herweh, Eric Jüttler, Peter D. Schellinger, Ernst Klotz, Peter Schramm Source Type: journals

Unusual Presentation of Sarcoidosis: Solitary Intracranial Mass Lesion Mimicking a GliomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a patient with sarcoidosis with an isolated intraparenchymal mass lesion that was similar to a glioma on magnetic resonance imaging. On fluid-attenuated inversion recovery images, a small hyperintense signal change in the right uncus was observed. Three months later, enlargement of the abnormal signal lesion was observed. An initial diagnosis of glioma was made. A biopsy of the temporal lobe tumor was done. On histology, a noncaseating granulomatous inflammation consistent with neurosarcoidosis was diagnosed. Albeit rarely, we should consider the possibility of neurosarcoidosis in the differential diagnosis of i...
Source: Journal of Neuroimaging - August 7, 2009 Category: Radiology Authors: Akinori Uruha, Reiji Koide, Makoto Taniguchi Source Type: journals

Multifocal Intradural Spinal AVF and Renal Artery Aneurysms in a Case of Klippel Trenaunay Syndrome (KTS)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report an interesting case of a young patient who had hypertrophy of right leg and nevoid geographic skin lesion on the dorsal aspect of the right foot and leg suggestive of Klippel Trenaunay syndrome (KTS) and who presented for spinal digital subtraction angiography (DSA) to investigate the cause of progressive weakness of bilateral lower limbs. DSA revealed spinal arteriovenous fistulae (AVFs) at 3 levels and bilateral renal artery aneurysms. Although multiple intradural spinal cord AVFs and renal artery aneurysms are considered a feature of KTS, their clear demonstration in a single case either alone or together is n...
Source: Journal of Neuroimaging - August 6, 2009 Category: Radiology Authors: Sandeep Sharma Source Type: journals

DWI Lesion Volume Reduction Following Acute Stroke Treatment with Transient Partial Aortic ObstructionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a patient who showed substantial reversal of her acute DWI lesion following partial aortic occlusion with Neuroflo[trade], a novel dual balloon catheter (Neuroflo[trade], CoAxia, MN). Case report/literature review. A 48-year-old woman presented with left-sided weakness and demonstrated an acute DWI lesion in the right middle cerebral artery territory, with diffusion-perfusion mismatch. She was enrolled into an experimental study in which a dual balloon catheter was inflated in the lower aorta. The patient improved and her postprocedure magnetic resonance image showed a significant reduction in lesion volume on d...
Source: Journal of Neuroimaging - August 6, 2009 Category: Radiology Authors: Muhammad S. Hussain, Yusuf A. Bhagat, Songling Liu, James Scozzafava, Khurshid A. Khan, William P. Dillon, Ashfaq Shuaib Source Type: journals

Evaluation of the Effects of Thyrotropin Releasing Hormone (TRH) Therapy on Regional Cerebral Blood Flow in the Cerebellar Variant of Multiple System Atrophy Using 3DSRTEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Thyrotropin releasing hormone (TRH) improves cerebellar ataxia and cerebellar perfusion in patients with spinocerebellar degeneration. It is not known whether TRH therapy can improve the cerebellar regional cerebral blood flow (rCBF) or not in patients with cerebellar variant of multiple-system atrophy (MSA-C). Seven patients with MSA-C received TRH intravenously (2 mg/day) for 14 days. Clinical efficacy was assessed using the International Cooperative Ataxia Rating Scale (ICARS) and brain perfusion single photon emission-computed tomography was performed before and after therapy. The rCBF in each region of interest (ROI) ...
Source: Journal of Neuroimaging - August 6, 2009 Category: Radiology Authors: Noriyuki Kimura, Toshihide Kumamoto, Teruaki Masuda, Yuki Nomura, Takuya Hanaoka, Yusuke Hazama, Toshio Okazaki Source Type: journals

Feasibility of Geometric-Intensity-Based Semi-Automated Delineation of the Tentorium Cerebelli from MRI ScansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This paper describes a feasibility study of a method for delineating the tentorium cerebelli in magnetic resonance imaging (MRI) brain scans. The tentorium cerebelli is a thin sheet of dura matter covering the cerebellum and separating it from the posterior part of the temporal lobe and the occipital lobe of the cerebral hemispheres. Cortical structures such as the parahippocampal gyrus can be indistinguishable from tentorium in magnetized prepared rapid gradient echo and T1-weighted MRI scans. Similar intensities in these neighboring regions make it difficult to perform accurate cortical analysis in neuroimaging studies o...
Source: Journal of Neuroimaging - July 30, 2009 Category: Radiology Authors: Neeraja Penumetcha, Suraj Kabadi, Bruno Jedynak, Charles Walcutt, Mokhtar H. Gado, Lei Wang, J. Tilak Ratnanather Source Type: journals

Rosai-Dorfman Disease with Massive Intracranial Involvement: Asymmetric Response to Conservative TherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Rosai-Dorfman Disease (RDD) is a rare, idiopathic lymphoproliferative disorder. Central nervous system (CNS) involvement in this disorder is an uncommon manifestation. The clinical and radiographic appearance of CNS RDD is variable, and may mimic more common diseases. Treatment is controversial, and spontaneous remission is common. Positive outcomes have been reported with radiation therapy, or corticosteroid administration, or surgical excision. Our case is unusual in that the extracranial sites of involvement responded to corticosteroid therapy while the intracranial masses progressed. J Neuroimaging 2009;XX:1[ndash]3. (...
Source: Journal of Neuroimaging - July 29, 2009 Category: Radiology Authors: Robert N. Walker, Thomas P. Nickles, Nektarios I. Lountzis, Darren L. Jacobs, Nava K. Nawaz Source Type: journals

Volumetric Asymmetry and Differential Aging Effect of the Human Caudate Nucleus in Normal Individuals: A Prospective MR Imaging StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to examine interhemispheric asymmetry in volume of the caudate nucleus and its age dependency. High-resolution T1-weighted brain magnetic resonance (MR) images were obtained for each subject using a 3-dimensional fast field-echo pulse sequence. The volumes of the bilateral caudate nuclei on MR images were measured using an automated method. Right-to-left comparison was made using paired t-test. Age-related change of right-to-left volume ratio (R/L ratio) was examined using Pearson's correlation coefficient. Fifty healthy right-handed Japanese male subjects (age 12 to 67 years, mean 39.6 years)...
Source: Journal of Neuroimaging - July 29, 2009 Category: Radiology Authors: Koji Yamashita, Takashi Yoshiura, Akio Hiwatashi, Tomoyuki Noguchi, Osamu Togao, Yukihisa Takayama, Eiki Nagao, Hironori Kamano, Masamitsu Hatakenaka, Hiroshi Honda Source Type: journals

Determination of Hemispheric Dominance with Mental Rotation Using Functional Transcranial Doppler Sonography and fMRIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to investigate specific activation patterns and potential gender differences during mental rotation and to investigate whether functional magnetic resonance imaging (fMRI) and functional transcranial Doppler sonography (fTCD) lateralize hemispheric dominance concordantly. Regional brain activation and hemispheric dominance during mental rotation (cube perspective test) were investigated in 10 female and 10 male healthy subjects using fMRI and fTCD. Significant activation was found in the superior parietal lobe, at the parieto-occipital border, in the middle and superior frontal gyrus bilaterally, ...
Source: Journal of Neuroimaging - July 28, 2009 Category: Radiology Authors: Katja Hattemer, Annika Plate, Johannes T. Heverhagen, Anja Haag, Boris Keil, Karl Martin Klein, Anke Hermsen, Wolfgang H. Oertel, Hajo M. Hamer, Felix Rosenow, Susanne Knake Source Type: journals

Thromboembolic Events Associated with Neuroform Stent™ in Endovascular Treatment of Intracranial AneurysmsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The incidence of thromboembolic events associated with Neuroform stent[trade] (Boston Scientific Target, Fremont, CA) is known from previous studies but there are uncertainties of scale. To report our rate of ischemic events associated with Neuroform stent[trade]. Consecutive patients treated with Neuroform stent[trade] for intracranial aneurysms were prospectively enrolled from January 2003 to August 2006. Thromboembolic events as well as clinical outcomes were measured. Mean follow-up was 12 months. Successful stent deployment was achieved in (65/67) 97% of patients without any ischemic event. However, postoperative thro...
Source: Journal of Neuroimaging - June 26, 2009 Category: Radiology Authors: Abutaher M. Yahia, Julius Latorre, Vickie Gordon, John Whapham, Ali Malek, Richard D. Fessler Source Type: journals

Spontaneous Thrombosis of a Large Vein of Galen MalformationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A large vein of Galen was diagnosed in a 9-month-old boy. This was not treated at birth, as there was no associated congestive heart failure. The patient was followed conservatively and follow-up magnetic resonance imaging showed increase in the size of the vein of Galen malformation. Subsequent cerebral angiogram demonstrated hypertrophied but thrombosed right posterior choroidal artery, suggesting spontaneous thrombosis of the arterial feeder and thus the embolization was not pursued. J Neuroimaging 2009;XX:1[ndash]2. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - June 25, 2009 Category: Radiology Authors: Qaisar A. Shah, Adnan I. Qureshi Source Type: journals

Brainstem Involvement in Sjögren's Syndrome-Related Sensory NeuronopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Magnetic resonance imaging (MRI) studies have shown abnormalities limited to T2-weighted high signal intensity in the posterior columns. A 65-year-old woman with Sjögren syndrome had slowly progressive unsteadiness of gait and limb paresthesias. A blink reflex examination suggested a paramedian brainstem lesion, confirmed by MRI. Sjögren's syndrome-related SN may be associated with a more diffuse immune-mediated aggression, involving also the brainstem, and leading to some of the blink reflex ...
Source: Journal of Neuroimaging - June 24, 2009 Category: Radiology Authors: Alfredo Damasceno, Marcondes C. França Jr, Verônica A. Zanardi, Anamarli Nucci Source Type: journals

Traumatic Carotid-Cavernous Fistula with Pontomesencephalic and Cervical Cord Venous Drainage Presenting as TetraparesisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 27-year-old male presented with progressive ascending myelopathy leading to tetraparesis. Magnetic resonance imaging of the cervical spine showed dilated perimedullary veins and spinal cord edema. Catheter angiography demonstrated a direct carotid-cavernous fistula (CCF) with prominent pontomesencephalic and perimedullary venous drainage. Successful coil embolization of the fistula was performed with improvement of the patient's symptoms. To our knowledge, no case of a direct CCF with perimedullary drainage has been previously reported. J Neuroimaging 2009;XX:1[ndash]3. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - June 24, 2009 Category: Radiology Authors: Diego A. Herrera, Sergio A. Vargas, Arthur B. Dublin Source Type: journals

Transvenous Embolization of a Symptomatic Venous Aneurysm Developing in the Drainage Network of a Deep Cerebral AVM: A Case ReportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a case of a symptomatic venous aneurysm that developed in the drainage network of a deep-seated basal ganglia and thalamic arteriovenous malformation. The venous aneurysm was treated selectively with platinum coils using a venous approach. J Neuroimaging 2009;XX:1[ndash]3. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - June 22, 2009 Category: Radiology Authors: Yves Benabu, Daniel Roy, Francois Guilbert, Jean Raymond, Alain Weill Source Type: journals

A Dural Arteriovenous Fistula of the Anterior Cranial Fossa Angiographically Mimicking an Anterior Ethmoidal Artery AneurysmEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a very unusual case of anterior cranial fossa DAVF angiographically mimicking an anterior ethmoidal artery aneurysm, which was ultimately corrected by surgery. A 41-year-old male presented with right frontal intraparenchymal hematoma with intraventricular extension. Angiography revealed a vascular lesion adjacent to the anterior fossa mimicking an anterior ethmoidal artery aneurysm, which was surgically proven to be a partially thrombosed venous varix of drainaging vein originated from the cribriform plate. A diagnosis of anterior cranial fossa DAVF was made, and venous varix was excised. Follow-up angiography af...
Source: Journal of Neuroimaging - June 22, 2009 Category: Radiology Authors: Zhi Chen, Weihua Tang, Zhi Liu, Fei Li, Hua Feng, Gang Zhu Source Type: journals

Diffusion Tensor Imaging Following Shunt in a Patient with HydrocephalusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a patient with hydrocephalus who was evaluated by diffusion tensor imaging (DTI) follow-up study before and after a shunt operation. A 48-year-old male patient and 6 age-matched control subjects were evaluated. The patient presented with hydrocephalus due to hemorrhage caused by the rupture of a right middle cerebral artery bifurcation aneurysm. Three longitudinal DTIs were acquired from the patient (pre-shunt, post-shunt 2 weeks, and post-shunt 8 weeks). The fractional anisotrophy values in the adjacent structures of the lateral ventricle, which were increased before the shunt operation, were decreased after ...
Source: Journal of Neuroimaging - June 22, 2009 Category: Radiology Authors: Sung Ho Jang, Seong Ho Kim Source Type: journals

Linguistic History of Posterior Reversible Encephalopathy Syndrome: Mirror of Developing KnowledgeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The term posterior reversible encephalopathy syndrome (PRES) was first proposed in 2000. Since then, the acronym PRES has become very popular in imaging and clinical literature as it is short, easy to say and remember, and neatly couples the frequent localization of neuroimaging findings along with the typical outcome of this syndrome. Another possible reason for the popularity of this acronym in clinical circles is the connotation of PRES with (elevated blood) PRESsure, as a majority of cases are believed to be associated with hypertension. However, problems exist with the interpretation and common understanding of PRES, ...
Source: Journal of Neuroimaging - June 22, 2009 Category: Radiology Authors: Zeev V. Maizlin, Hournaz Ghandehari, Leonid Maizels, Jason R. Shewchuk, John M. Kirby, Parag Vora, Jason J. Clement Source Type: journals

PICA Origin Aneurysm Diagnosed 27 Years after Microvascular Decompression of Cranial Nerve VIIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The authors report a case of a posterior inferior cerebellar artery origin aneurysm causing brainstem compression and swallowing difficulty. The patient had an ipsilateral microvascular decompression of cranial nerve VII for hemifacial spasm 27 years prior to the discovery of the aneurysm. The aneurysm was successfully treated endovascularly. A discussion of possible etiologies of the aneurysm's formation is presented. J Neuroimaging 2009;XX:1[ndash]4. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - June 22, 2009 Category: Radiology Authors: Matthew J. Tormenti, Ridwan Lin, Brian T. Jankowitz, Michael B. Horowitz Source Type: journals

Parry-Romberg Syndrome and Rasmussen Encephalitis: Possible Association. Clinical and Neuroimaging FeaturesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the clinical and neuroradiological findings in a 6-year-old boy, presenting with focal hemifacial and arm motor seizures and progressive facial hemiatrophy. Serial MR imaging studies revealed progressive brain hemispheric signal alterations and atrophy. This would thus suggest acoexistence of PRS and RE. J Neuroimaging 2009;XX:1[ndash]6. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - June 22, 2009 Category: Radiology Authors: Daniela Longo, Amalia Paonessa, Nicola Specchio, Luciana Nogueira Delfino, Dianela Claps, Lucia Fusco, Francesco Randisi, Elisabetta Genovese, Federico Vigevano, Giuseppe Fariello Source Type: journals

Thrombosis of a Drainage Vein in Developmental Venous Anomaly (DVA) Leading Venous Infarction: A Case Report and Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report imaging findings of posterior fossa DVA with a thrombosed drainage vein in a patient with nonhemorrhagic cerebellar infarct. We also review the relevant literature on the subject. J Neuroimaging 2009;XX:1[ndash]5. (Source: Journal of Neuroimaging)
Source: Journal of Neuroimaging - June 22, 2009 Category: Radiology Authors: Yilmaz Kiroglu, Ismail Oran, Tayfun Dalbasti, Nevzat Karabulut, Cem Calli Source Type: journals