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Long-term results of thalamic deep brain stimulation for essential tremor.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Deep brain stimulation of the VIM is an efficient and safe treatment for ET. Tremor and handwriting improvements in long-term follow-up are stable. The patients' perception of their outcome is quite good. However, tolerance may develop in some patients requiring changes in stimulation parameters. PMID: 19911883 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Zhang K, Bhatia S, Oh MY, Cohen D, Angle C, Whiting D Tags: J Neurosurg Source Type: journals

Ventricular enlargement due to acute hypernatremia in a patient with a ventriculoperitoneal shunt.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patients requiring CSF shunts frequently have comorbidities that can influence water and electrolyte balances. The authors report on a case involving a ventriculoperitoneal shunt in a patient who underwent intravenous hyperhydration and withdrawal of vasopressin substitution prior to scheduled high-dose chemotherapy regimen for a metastatic suprasellar germinoma. After acute neurological deterioration, the patient underwent CT scanning that demonstrated ventriculomegaly. A shunt tap revealed no flow and negative opening pressure. Due to suspicion of proximal shunt malfunction, the comatose patient underwent immediate s...
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Andres RH, Pendharkar AV, Kuhlen D, Mariani L Tags: J Neurosurg Source Type: journals

Atypical teratoid/rhabdoid tumor of the pineal region in an adult.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
An atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant embryonal tumor most often occurring in the posterior fossa in children younger than 3 years of age. Adult cases of AT/RT are very rare, and 27 cases with a diagnosis of either AT/RT or (malignant) rhabdoid tumor have been reported to date. The authors report an adult case of an AT/RT occurring in the pineal region with molecular cytogenetic and immunohistochemical confirmation. A 33-year-old woman presented with a 2-month history of headache and blurred vision progressing to diplopia, and was admitted emergently due to deteriorating mental status. An MR...
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Takei H, Adesina AM, Mehta V, Powell SZ, Langford LA Tags: J Neurosurg Source Type: journals

Hypomania with hypersexuality following bilateral anterior limb stimulation in obsessive-compulsive disorder.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This 28-year-old Chinese man was referred for deep brain stimulation (DBS) evaluation for an 8-year history of refractory obsessive-compulsive disorder. After the patient had signed an informed consent, the authors implanted DBS leads. Hypomania with hypersexuality was noted on stimulation at Contact 2 and became aggravated with a higher voltage (>/=3 V) during chronic bilateral DBS. After the voltage was decreased to 1 V, the patient's hypomanic symptoms subsided and his libido returned to baseline. PMID: 19911886 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Chang CH, Chen SY, Hsiao YL, Tsai ST, Tsai HC Tags: J Neurosurg Source Type: journals

Nationwide study of decompressive surgery for malignant supratentorial infarction in the Czech Republic: utilization and outcome predictors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In 2006 decompressive surgery was underutilized and occurred late in the clinical course in the Czech Republic. Revision of national guidelines is necessary to incorporate the latest data and ensure that the patients who can benefit most receive treatment. PMID: 19911887 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Bar M, Mikulik R, Skoloudík D, Czerny D, Lipina R, Klecka L, Juran V, Mraček J, Vondráčková D, Hrabalek L, Brzezny R, Dienelt J Tags: J Neurosurg Source Type: journals

Resection of malignant brain tumors in eloquent cortical areas: a new multimodal approach combining 5-aminolevulinic acid and intraoperative monitoring.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The authors' first results show that tumor resections with 5-ALA in combination with intraoperative cortical stimulation have the advantages of both methods and, thus, provide additional safety for the neurosurgeon during resections of primary malignant brain tumors in eloquent areas. Nonetheless, more cases and additional studies are necessary to further prove the advantages of this multimodal strategy. PMID: 19911888 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Feigl GC, Ritz R, Moraes M, Klein J, Ramina K, Gharabaghi A, Krischek B, Danz S, Bornemann A, Liebsch M, Tatagiba MS Tags: J Neurosurg Source Type: journals

Cerebrospinal fluid shunt insertion: techniques of peritoneal catheter placement separate from abdominal fascial and peritoneal incisions.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, the authors describe a simple technique for passing the peritoneal catheter of a ventriculoperitoneal shunt through the abdominal wall on a pathway separate from the fascial opening. This technique minimizes the risk of abdominal wall-related complications and is especially important in high-risk patients such as those with obesity and/or diabetes and in children. PMID: 19911889 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Elashaal AA, Corrin M, Cusimano MD Tags: J Neurosurg Source Type: journals

Intracellular free magnesium of brain and cerebral phosphorus-containing metabolites after subarachnoid hemorrhage and hypermagnesemic treatment: a (31)P-magnetic resonance spectroscopy study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The MRS finding of elevated brain free intracellular magnesium after intravenous magnesium sulfate infusion is novel, and the changes in membrane metabolism provide insight into the metabolic effects of aneurysmal SAH and future pathophysiological studies. PMID: 19911890 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Wong GK, Yeung DK, Ahuja AT, King AD, Lam CW, Chan MT, Gin T, Poon WS Tags: J Neurosurg Source Type: journals

Burst stimulation of the auditory cortex: a new form of neurostimulation for noise-like tinnitus suppression.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Burst stimulation is a new form of neurostimulation that might be helpful in treating symptoms that are intractable to conventional tonic stimulation. Further exploration of this new stimulation design is warranted. PMID: 19911891 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: De Ridder D, Vanneste S, van der Loo E, Plazier M, Menovsky T, van de Heyning P Tags: J Neurosurg Source Type: journals

Age- and time-dependent effects on functional outcome and cortical activation pattern in patients with median nerve injury: a functional magnetic resonance imaging study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Following a median nerve injury (1-11 years after injury) there may be an initial increase in the volume of the cortical representation, which subsequently declines during the restoration phase. These dynamic changes may involve both median and ulnar nerve cortical representation, because both showed negative correlation with time after injury. These findings are in agreement with animal studies showing that cortical plasticity is an important mechanism for functional recovery after peripheral nerve injury and repair. PMID: 19911892 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Fornander L, Nyman T, Hansson T, Ragnehed M, Brismar T Tags: J Neurosurg Source Type: journals

Cellular transplantation for the nervous system: impact of time after preparation on cell viability and survival.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The authors' results indicate that that there can be significant losses in viability between preparation and implantation and that more sophisticated methods of evaluation, such as the ability of cells to attach to a substrate and grow, may be required to detect decreases in viability. The time between preparation and implantation will be an important factor in clinical trial design. PMID: 19911893 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Gobbel GT, Kondziolka D, Fellows-Mayle W, Uram M Tags: J Neurosurg Source Type: journals

Continuous hypertension and tachycardia after resection of a hemangioblastoma behind the dorsal medulla oblongata: relationship to sympathetic overactivity at the neurogenic vasomotor center.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A very rare case of continuous hypertension and tachycardia after excision of a cerebellar hemangioblastoma at the dorsal medulla oblongata is presented. This 21-year-old man was admitted to the authors' hospital with a headache and dizziness. Radiological examination revealed a tumor located behind the dorsal medulla oblongata and compressing it substantially. The tumor was completely resected, but after the surgery the patient experienced prolonged hypertension and tachycardia. Postoperative MR imaging showed a small injury at the dorsocaudal medulla that was located at the caudal site of the nucleus of the tractus s...
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Ideguchi M, Kajiwara K, Yoshikawa K, Kato S, Ishihara H, Fujii M, Fujisawa H, Suzuki M Tags: J Neurosurg Source Type: journals

Effectiveness of an epidural blood patch for patients with intracranial hypotension syndrome and persistent spinal epidural fluid collection after treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions An epidural blood patch is effective for sealing of CSF leaks, but the resolution of SIHS-related symptoms does not always imply complete eradication of the leakage. PMID: 19911895 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Horikoshi T, Watanabe A, Uchida M, Kinouchi H Tags: J Neurosurg Source Type: journals

Trigeminal neurinomas with extracranial extension: analysis of 28 surgically treated cases.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Extracranial extensions of trigeminal neurinomas have a well-defined meningeal covering. In most cases resection was performed via a minimally invasive cranial avenue (a "reverse skull base approach"). Radical resection was associated with an excellent long-term outcome. PMID: 19895193 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Goel A, Shah A, Muzumdar D, Nadkarni T, Chagla A Tags: J Neurosurg Source Type: journals

Image-guided anatomical and morphometric study of supraorbital and transorbital minicraniotomies to the sellar and perisellar regions: comparison with standard techniques.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In refining the concept of working area as deep rather than superficial in the surgical field, the authors quantified the 6 triangles whose boundaries were relative to the target structures to be exposed in the approach. The authors' morphometric findings support the use of the supraorbital and transorbital approaches as a valid alternative to the pterional approach for the treatment of sellar and perisellar pathology. The transorbital approach combines the advantages of minimal invasiveness with those of cranial base techniques. PMID: 19895194 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Beretta F, Andaluz N, Chalaala C, Bernucci C, Salud L, Zuccarello M Tags: J Neurosurg Source Type: journals

A unifying hypothesis for a patient with superficial siderosis, low-pressure headache, intraspinal cyst, back pain, and prominent vascularity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A source of bleeding is often not evident during the evaluation of patients with superficial siderosis of the CNS despite extensive imaging. An intraspinal fluid-filled collection of variable dimensions is frequently observed on spine MR imaging in patients with idiopathic superficial siderosis. A similar finding has also been reported in patients with idiopathic intracranial hypotension. The authors report on a patient with superficial siderosis and a longitudinally extensive intraspinal fluid-filled collection secondary to a dural tear. The patient had a history of low-pressure headaches. His spine MR imaging and spi...
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Kumar N, Miller GM, Piepgras DG, Mokri B Tags: J Neurosurg Source Type: journals

Imaging of hypoxic lesions in patients with gliomas by using positron emission tomography with 1-(2-[(18)F] fluoro-1-[hydroxymethyl]ethoxy)methyl-2-nitroimidazole, a new (18)F-labeled 2-nitroimidazole analog.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Imaging with FRP-170 PET can visualize hypoxic lesions in patients with glioma, as confirmed by histological examination. This new method can assess tumor hypoxia preoperatively and noninvasively. PMID: 19895196 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Shibahara I, Kumabe T, Kanamori M, Saito R, Sonoda Y, Watanabe M, Iwata R, Higano S, Takanami K, Takai Y, Tominaga T Tags: J Neurosurg Source Type: journals

Gamma Knife thalamotomy for treatment of essential tremor: long-term results.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions A VIM thalamotomy with the Leksell GK offers a safe and effective alternative for surgical treatment of ET. It is particularly applicable to patients who are not ideal candidates for deep brain stimulation but can be offered to all patients who are considering surgical intervention for ET. PMID: 19895197 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Young RF, Li F, Vermeulen S, Meier R Tags: J Neurosurg Source Type: journals

The sublime bridge: anatomy and implications in median nerve entrapment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Based on the authors' study, pronator syndrome is an incorrect term applied to compression of the median nerve at the sublime bridge. This potential site of median nerve compression is distinct and has characteristics that can clinically differentiate it from compression of the median nerve between the heads of the pronator teres. The authors hope that these data will be of use to the surgeon in the evaluation and treatment of patients with proximal median nerve entrapment. PMID: 19895198 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Tubbs RS, Marshall T, Loukas M, Shoja MM, Cohen-Gadol AA Tags: J Neurosurg Source Type: journals

Vaccine therapy with dendritic cells transfected with Il13ra2 mRNA for glioma in mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These results demonstrate the therapeutic potential of vaccination with dendritic cells transfected with Il13ra2 mRNA for the treatment of malignant glioma. PMID: 19895199 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Saka M, Amano T, Kajiwara K, Yoshikawa K, Ideguchi M, Nomura S, Fujisawa H, Kato S, Fujii M, Ueno K, Hinoda Y, Suzuki M Tags: J Neurosurg Source Type: journals

Effect of subthalamic deep brain stimulation on postural abnormality in Parkinson disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Postural abnormality in patients with PD could be ameliorated by STN DBS, and therefore surgery should be considered before irreversible spinal deformity develops. PMID: 19895200 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Umemura A, Oka Y, Ohkita K, Yamawaki T, Yamada K Tags: J Neurosurg Source Type: journals

Adenosine A(2A) receptors in early ischemic vascular injury after subarachnoid hemorrhage.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These results demonstrate that global inactivation of A(2A) receptors decreases the intensity of the early vascular response to SAH. Early inhibition of A(2A) receptors after SAH might reduce cerebral injury. PMID: 19895201 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Sehba FA, Flores R, Muller A, Friedrich V, Chen JF, Britz GW, Winn HR, Bederson JB Tags: J Neurosurg Source Type: journals

Attenuation of astrogliosis and modulation of endothelial growth factor receptor in lipid rafts by simvastatin after traumatic brain injury.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These data suggest that simvastatin reduces reactive astrogliosis and rescues neuronal cells after TBI. These beneficial effects of simvastatin may be mediated by inhibiting astrocyte activation after TBI through modifying the caveolin-1 expression in lipid rafts and the subsequent modulation of EGFR phosphorylation in lipid rafts. PMID: 19895202 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Wu H, Mahmood A, Lu D, Jiang H, Xiong Y, Zhou D, Chopp M Tags: J Neurosurg Source Type: journals

Transfer of supinator motor branches to the posterior interosseous nerve in C7-T1 brachial plexus palsy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Transferring supinator motor nerves directly to the posterior interosseous nerve is effective in at least partially restoring thumb and finger extension in patients with lower-type injuries of the brachial plexus. PMID: 19895203 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Bertelli JA, Ghizoni MF Tags: J Neurosurg Source Type: journals

Microsurgical removal of Onyx HD-500 from an aneurysm for relief of brainstem compression.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The authors report the successful removal of Onyx HD-500 from an aneurysm sac by means of ultrasonic aspiration. This 46-year-old woman presented with progressive spasms of her left arm and leg due to mass effect and compression on the right cerebral peduncle 5 years after endovascular treatment of an unruptured giant posterior communicating artery aneurysm with Onyx HD-500. No filling of the aneurysm was detected on angiography. The patient underwent a right pterional craniotomy and the aneurysm was opened to remove the Onyx mass. However, contrary to expectations, the aneurysm was still patent, filling with blood bet...
Source: Journal of Neurosurgery - November 6, 2009 Category: Neurosurgery Authors: Van Loock K, Menovsky T, Voormolen MH, Plazier M, Parizel P, De Ridder D, Maas AI, Hernesniemi JA Tags: J Neurosurg Source Type: journals

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PMID: 19891031 [PubMed - in process] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 1, 2009 Category: Neurosurgery Authors: Noudel R Tags: J Neurosurg Source Type: journals

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PMID: 19886001 [PubMed - in process] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 1, 2009 Category: Neurosurgery Authors: Mitsuhashi Y, Aurboonyawat T, Pereira VM, Geibprasert S, Toulgoat F, Ozanne A Tags: J Neurosurg Source Type: journals

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PMID: 19886002 [PubMed - in process] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 1, 2009 Category: Neurosurgery Authors: Ferrell AS, Tubbs RS, Acakpo-Satchivi L Tags: J Neurosurg Source Type: journals

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PMID: 19886003 [PubMed - in process] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 1, 2009 Category: Neurosurgery Authors: Samuelsson C, Howells T, Kumlien E, Enblad P, Hillered L, Ronne-Engström E Tags: J Neurosurg Source Type: journals

Alleviation of off-period dystonia in Parkinson disease by a microlesion following subthalamic implantation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The author postulated that off-period dystonia alleviation may reflect both a microsubthalamotomy and micropallidotomy effect. They hypothesize, moreover, that the microlesion could play a role in the 6-month postoperative outcome. PMID: 19877801 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 30, 2009 Category: Neurosurgery Authors: Derrey S, Lefaucheur R, Chastan N, Gérardin E, Hannequin D, Desbordes M, Maltête D Tags: J Neurosurg Source Type: journals

Ultrahigh-dose intraarterial infusion of verapamil through an indwelling microcatheter for medically refractory severe vasospasm: initial experience.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Prolonged intraarterial infusion of verapamil is a safe and effective treatment for medically refractory severe vasospasm and reduces the need for angioplasty in such cases. PMID: 19877802 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 30, 2009 Category: Neurosurgery Authors: Albanese E, Russo A, Quiroga M, Willis RN, Mericle RA, Ulm AJ Tags: J Neurosurg Source Type: journals

Slowly progressive neuronal death associated with postischemic hyperperfusion in cortical laminar necrosis after high-flow bypass for a carotid intracavernous aneurysm.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report illustrates, for the first time, dynamic neuroradiological correlations between slowly progressive neuronal death shown by (123)I-IMZ SPECT and cortical laminar necrosis on MR imaging in human stroke. PMID: 19877803 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 30, 2009 Category: Neurosurgery Authors: Iihara K, Okawa M, Hishikawa T, Yamada N, Fukushima K, Iida H, Miyamoto S Tags: J Neurosurg Source Type: journals

Editorial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19877804 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 30, 2009 Category: Neurosurgery Authors: Samii M, Gerganov VM Tags: J Neurosurg Source Type: journals

A modified far-lateral approach for large or giant meningiomas of the posterior fossa.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions A modified far-lateral approach to the posterior fossa and CPA allows for safe, and often total, resection of large meningiomas with minimal morbidity. While avoiding the risks of condylar resection, this microsurgical strategy allows for greater field of view, minimal venous bleeding, and immediate access to the spinal subarachnoid space. PMID: 19877805 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 30, 2009 Category: Neurosurgery Authors: Sanai N, McDermott MW Tags: J Neurosurg Source Type: journals

Choosing the best operation for chronic subdural hematoma: a decision analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Bur-hole craniostomy is the most efficient choice for surgical drainage of uncomplicated CSDH. Bur-hole craniostomy balances a low recurrence rate with a low incidence of highly morbid complications. Decision analysis provides statistical and empirical guidance in the absence of well-controlled large trials and despite a confusing range of previously reported morbidity and recurrence. PMID: 19877806 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 30, 2009 Category: Neurosurgery Authors: Lega BC, Danish SF, Malhotra NR, Sonnad SS, Stein SC Tags: J Neurosurg Source Type: journals

Recurrence rates after neuroendoscopic fenestration and Gamma Knife surgery in comparison with subtotal resection and Gamma Knife surgery for the treatment of cystic craniopharyngiomas.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions This investigation confirms that STR followed by GKS results in a lower recurrence rate than neuroendoscopy and GKS. Neuroendoscopy and GKS, however, results in a better preservation of endocrine function. These results suggest that a generalized multimodal approach including endoscopic fenestration in addition to GKS is hindered by higher recurrence rates. PMID: 19877807 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 30, 2009 Category: Neurosurgery Authors: Park YS, Chang JH, Park YG, Kim DS Tags: J Neurosurg Source Type: journals

Endovascular coil occlusion of 152 middle cerebral artery aneurysms: initial and midterm angiographic and clinical results.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Risks and initial and midterm angiographic and clinical results after endovascular treatment of MCA aneurysms are nearly identical to other locations. Endovascular treatment may thus be proposed as an alternative to surgical clipping at this location. Nevertheless, a longer follow-up period is necessary to determine its efficacy, particularly in cases of unruptured aneurysms. PMID: 19852536 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Bracard S, Abdel-Kerim A, Thuillier L, Klein O, Anxionnat R, Finitsis S, Lebedinsky A, de Freitas CM, Pinheiro N, de Andrade GC, Picard L Tags: J Neurosurg Source Type: journals

The impact of therapeutic modality on outcomes following repair of ruptured intracranial aneurysms: an administrative data analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The results of the current analysis call into question the generalizability of the ISAT to all ruptured aneurysms. Given the limitations inherent in this form of analysis, further clinical studies-rigorously assessing the performance of endovascular therapy in patients with non-ISAT-like aneurysms-are indicated. PMID: 19852537 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: O'Kelly CJ, Kulkarni AV, Austin PC, Wallace MC, Urbach D Tags: J Neurosurg Source Type: journals

Microvascular decompression of the optic chiasm.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Elongation of the anterior cerebral artery (ACA) and subsequent compression of the chiasm rarely have been reported as causes of a visual field deficit. Neither has microvascular decompression of the chiasm been described in this circumstance. The authors report on a case of progressive visual deficits caused by compression of the optic apparatus by a right elongated ACA as documented on MR imaging. Microvascular decompression was proposed as treatment. The right A(1) segment was larger than usual and tortuous, transmitting its pulsations into the chiasm. A piece of Teflon was inserted between the A(1) segment and the ...
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: McLaughlin N, Bojanowski MW Tags: J Neurosurg Source Type: journals

Induction of panic attack by stimulation of the ventromedial hypothalamus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Panic attacks are sudden debilitating attacks of intense distress often accompanied by physical symptoms such as shortness of breath and heart palpitations. Numerous brain regions, hormones, and neurotransmitter systems are putatively involved, but the etiology and neurocircuitry of panic attacks is far from established. One particular brain region of interest is the ventromedial hypothalamus (VMH). In cats and rats, electrical stimulation delivered to the VMH has been shown to evoke an emotional "panic attack-like" escape behavior, and in humans, stimulation targeting nuclei just posterior or anterior to the VMH has r...
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Wilent WB, Oh MY, Buetefisch CM, Bailes JE, Cantella D, Angle C, Whiting DM Tags: J Neurosurg Source Type: journals

A prospective, randomized clinical trial to compare the effect of hyperbaric to normobaric hyperoxia on cerebral metabolism, intracranial pressure, and oxygen toxicity in severe traumatic brain injury.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Hyperbaric O(2) has a more robust posttreatment effect than NBH on oxidative cerebral metabolism related to its ability to produce a brain tissue PO(2) >/= 200 mm Hg. However, it appears that O(2) treatment for severe TBI is not an all or nothing phenomenon but represents a graduated effect. No signs of pulmonary or cerebral O(2) toxicity were present. PMID: 19852540 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Rockswold SB, Rockswold GL, Zaun DA, Zhang X, Cerra CE, Bergman TA, Liu J Tags: J Neurosurg Source Type: journals

Prevalence and impact of diffuse axonal injury in patients with moderate and severe head injury: a cohort study of early magnetic resonance imaging findings and 1-year outcome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Diffuse axonal injury was found in almost three-quarters of the patients with moderate and severe head injury who survived the acute phase. Diffuse axonal injury influenced the level of consciousness, and only in patients with DAI was GCS score related to outcome. Finally, DAI was a negative prognostic sign only when located in the brainstem. PMID: 19852541 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Skandsen T, Kvistad KA, Solheim O, Strand IH, Folvik M, Vik A Tags: J Neurosurg Source Type: journals

Preoperative evaluation of neurovascular relationships for microvascular decompression in the cerebellopontine angle in a virtual reality environment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The Dextroscope system is an easy and rapid method to create a stereoscopic neurovascular model for MVD that is highly concordant with intraoperative findings. It effectively shortens the learning curve and adds to the surgeon's confidence. PMID: 19852542 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Du ZY, Gao X, Zhang XL, Wang ZQ, Tang WJ Tags: J Neurosurg Source Type: journals

Toll-like receptor 4 expression during cerebral aneurysm formation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Toll-like receptor 4 was expressed in cerebral aneurysm walls both in rats and humans. This receptor may play a crucial role in cerebral aneurysm formation through NF-kappaB activation in endothelial cells. The results of the present study will shed new light on the pathogenesis of cerebral aneurysm formation. PMID: 19852543 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Aoki T, Nishimura M, Ishibashi R, Kataoka H, Takagi Y, Hashimoto N Tags: J Neurosurg Source Type: journals

Editorial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19852544 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Lanzino G, Brinjikji W Tags: J Neurosurg Source Type: journals

Gamma Knife radiosurgery for trigeminal neuralgia: the impact of magnetic resonance imaging-detected vascular impingement of the affected nerve.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Vascular impingement of the affected nerve was seen in the majority of patients with trigeminal neuralgia. Overall pain relief following GKRS was comparable in those with and without evidence of vascular compression on MR imaging. In subgroup analysis of those with MR imaging evidence of vessel impingement of the affected trigeminal nerve, pain relief correlated with a higher dose to the point of contact between the impinging vessel and the trigeminal nerve. Such a finding may point to vascular changes affording at least some degree of relief following GKRS for trigeminal neuralgia. PMID: 19852545 [PubMed -...
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Sheehan JP, Ray DK, Monteith S, Yen CP, Lesnick J, Kersh R, Schlesinger D Tags: J Neurosurg Source Type: journals

Editorial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19852546 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 23, 2009 Category: Neurosurgery Authors: Bullock MR Tags: J Neurosurg Source Type: journals

Treatment of brain arteriovenous malformations with high-flow arteriovenous fistulas: risk and complications associated with endovascular embolization in multimodality treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Endovascular occlusion of the fistulous component was successfully achieved in every patient; every endovascular complication in this series was related to other procedures such as nidus embolization. The importance of the fistula treatment should be emphasized to minimize the endovascular complications and to maximize the treatment effect when a multimodality therapy is used to treat brain AVMs with large AVF. PMID: 19835467 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 15, 2009 Category: Neurosurgery Authors: Yuki I, Kim RH, Duckwiler G, Jahan R, Tateshima S, Gonzalez N, Gorgulho A, Diaz JL, De Salles AA, Viñuela F Tags: J Neurosurg Source Type: journals

Schwannoma of the greater superficial petrosal nerve.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The authors report the clinical features, imaging and surgical findings, and follow-up of 5 rare cases of schwannoma of the middle fossa with possible origin from the greater superficial petrosal nerve (GSPN). All patients presented to a single neurosurgical institution. The study design was a prospective follow-up of 5 cases of schwannomas of the middle fossa that most likely originated from the GSPN. The presenting features were burning pain in the eyes in 2 cases, epilepsy and behavioral changes in 2 cases, and headache in 1 case. Imaging studies showed a subtemporal mass on the anterosuperior aspect of the petrous ...
Source: Journal of Neurosurgery - October 15, 2009 Category: Neurosurgery Authors: Amirjamshidi A, Hashemi SM, Abbassioun K Tags: J Neurosurg Source Type: journals

Heparanase expression of glioma in human and animal models.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Glioma tissues contain increased levels of heparanase. Multiple cell types contribute to the expression of heparanase, including neovessel endothelial cells, tumor cells, and infiltrated neutrophils. Heparanase plays an important role in the control of cell proliferation and invasion. Animal models using Ast11.9-2 and primary neurospheres are suitable for antitumor studies targeting heparanase. PMID: 19835469 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 15, 2009 Category: Neurosurgery Authors: Hong X, Nelson KK, Decarvalho AC, Kalkanis SN Tags: J Neurosurg Source Type: journals