Microbiological assessment of success and failure in pulp revitalization: a randomized clinical trial using calcium hydroxide and chlorhexidine gluconate in traumatized immature necrotic teeth
CONCLUSIONS: There were no statistical differences in CH and CHD efficacy. At S5, microflora persisted in both successful and failed outcomes, but the abundance and diversity increased significantly only in the failed cases. The successful outcomes presented higher diversity and higher decreases of the primary microflora at S5 than the failed outcomes. The abundance and diversity increased significantly at S5 only in failed cases.PMID:38665416 | PMC:PMC11044761 | DOI:10.1080/20002297.2024.2343518 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 26, 2024 Category: Microbiology Authors: Alina Wikstr öm Nelly Romani Vestman Olena Rakhimova David Lazaro Gimeno Georgios Tsilingaridis Malin Brundin Source Type: research

Comparison of the performance of MiSeq and NovaSeq in oral microbiome study
CONCLUSION: Taken together, while both MiSeq and NovaSeq platforms effectively characterize the oral microbiome, NovaSeq outperformed MiSeq in terms of read counts and detection of unique OTUs, highlighting its potential as a valuable tool for large scale oral microbiome studies.PMID:38645704 | PMC:PMC11028001 | DOI:10.1080/20002297.2024.2344293 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 22, 2024 Category: Microbiology Authors: Hyejung Han Hyo-Jung Lee Keun-Suh Kim Jin Chung Hee Sam Na Source Type: research

Characterization of the unique oral microbiome of children harboring < em > Helicobacter pylori < /em > in the oral cavity
CONCLUSION: These results suggest unique oral microbiome characteristics in children with H. pylori infection in the oral cavity.PMID:38617439 | PMC:PMC11011227 | DOI:10.1080/20002297.2024.2339158 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 15, 2024 Category: Microbiology Authors: Yuko Ogaya Tamami Kadota Masakazu Hamada Ryota Nomura Kazuhiko Nakano Source Type: research

Unveiling the complexity of early childhood caries: < em > Candida albicans < /em > and < em > Streptococcus mutans < /em > cooperative strategies in carbohydrate metabolism and virulence
CONCLUSION: The symbiotic relationship between C. albicans and S. mutans, and their interactions through carbohydrate metabolism and environmental acidification, are key factors in the pathogenesis of ECC. A comprehensive understanding of these mechanisms is crucial for developing effective strategies to manage and treat ECC.PMID:38606339 | PMC:PMC11008315 | DOI:10.1080/20002297.2024.2339161 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 12, 2024 Category: Microbiology Authors: Pingping Jin Lu Wang Daozhen Chen Yu Chen Source Type: research

Role of ferroptosis in < em > Porphyromonas gingivalis- < /em > induced impairment of epithelial junction
CONCLUSIONS: Our study demonstrated that P. gingivalis weakened the oral epithelial barrier by causing ferroptosis via inhibiting SLC7A11/GSH/GPX4 axis.PMID:38562512 | PMC:PMC10984227 | DOI:10.1080/20002297.2024.2334578 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 2, 2024 Category: Microbiology Authors: Xiaoting Shi Jinwen Liu Ze Lu Jiabo Li Shuwei Zhang Qian Li Fengxue Geng Yaping Pan Source Type: research

A rare case of necrotizing fasciitis of the leg in an intravenous drug user caused by < em > Prevotella denticola < /em >
CONCLUSIONS: In IDUs the risk of deep skin and soft tissue infections is high and may be aggravated by contamination with oral microorganisms. The choice of empirical antibiotic treatment should include agents active against oral cavity anaerobes, such as P. denticola.PMID:38562513 | PMC:PMC10984238 | DOI:10.1080/20002297.2024.2334545 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 2, 2024 Category: Microbiology Authors: Andrea Bedini Filippo Medioli Altea Gallerani Irene Venturelli Giacomo Franceschi Marianna Meschiari Erica Franceschini Giacomo Maria Lima Mario Sarti Cristina Mussini Source Type: research

Role of ferroptosis in < em > Porphyromonas gingivalis- < /em > induced impairment of epithelial junction
CONCLUSIONS: Our study demonstrated that P. gingivalis weakened the oral epithelial barrier by causing ferroptosis via inhibiting SLC7A11/GSH/GPX4 axis.PMID:38562512 | PMC:PMC10984227 | DOI:10.1080/20002297.2024.2334578 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 2, 2024 Category: Microbiology Authors: Xiaoting Shi Jinwen Liu Ze Lu Jiabo Li Shuwei Zhang Qian Li Fengxue Geng Yaping Pan Source Type: research

A rare case of necrotizing fasciitis of the leg in an intravenous drug user caused by < em > Prevotella denticola < /em >
CONCLUSIONS: In IDUs the risk of deep skin and soft tissue infections is high and may be aggravated by contamination with oral microorganisms. The choice of empirical antibiotic treatment should include agents active against oral cavity anaerobes, such as P. denticola.PMID:38562513 | PMC:PMC10984238 | DOI:10.1080/20002297.2024.2334545 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 2, 2024 Category: Microbiology Authors: Andrea Bedini Filippo Medioli Altea Gallerani Irene Venturelli Giacomo Franceschi Marianna Meschiari Erica Franceschini Giacomo Maria Lima Mario Sarti Cristina Mussini Source Type: research

Role of ferroptosis in < em > Porphyromonas gingivalis- < /em > induced impairment of epithelial junction
CONCLUSIONS: Our study demonstrated that P. gingivalis weakened the oral epithelial barrier by causing ferroptosis via inhibiting SLC7A11/GSH/GPX4 axis.PMID:38562512 | PMC:PMC10984227 | DOI:10.1080/20002297.2024.2334578 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 2, 2024 Category: Microbiology Authors: Xiaoting Shi Jinwen Liu Ze Lu Jiabo Li Shuwei Zhang Qian Li Fengxue Geng Yaping Pan Source Type: research