Microanatomical changes and biomolecular expression at the PDL ‐entheses during experimental tooth movement
The novel aspect of this study was to contextualize the co ‐localization of biomolecular expression in widened and narrowed periodontal ligament (PDL)‐space within a mechanically activated periodontal complex. The PDL is unique as it is the only ligament with both innervation and vascularization. Maxillary molars in 6‐week‐old male C57BL/6 mice (N  = 5) were experimentally translated for 2 weeks using an elastic spacer. Contralateral teeth were used as controls. Mechanical testing of the periodontal complex of a mouse in situ and imaging using X‐ray micro‐computed tomography (micro‐XCT) illustrated deforma...
Source: Journal of Periodontal Research - November 28, 2018 Category: Dentistry Authors: Lynn Yang, Misun Kang, Rui He, Bo Meng, Arvin Pal, Ling Chen, Andrew H. Jheon, Sunita P. Ho Tags: ORIGINAL ARTICLE Source Type: research

A comprehensive study on donor ‐matched comparisons of three types of mesenchymal stem cells‐containing cells from human dental tissue
ConclusionThese three types of dental MSCs showed different biological characteristics. MSCs/PDLCs are the best candidate cells for bone regeneration, but the application of MSCs/PDLCs might be limited to certain number of passages. Improving the differentiation of MSCs/GCs remains the key issue regarding their application in tissue engineering. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 25, 2018 Category: Dentistry Authors: Yixiao Xing, Yunpeng Zhang, Xuan Wu, Bin Zhao, Yawen Ji, Xin Xu Tags: ORIGINAL ARTICLE Source Type: research

Comparison between different isoelectric points of biodegradable gelatin sponges incorporating β‐tricalcium phosphate and recombinant human fibroblast growth factor‐2 for ridge augmentation: A preclinical study of saddle‐type defects in dogs
ConclusionsThese findings suggest that in ridge augmentation of saddle ‐type defects, controlled release of rhFGF‐2 induces notably more alveolar bone formation than does short‐term application of rhFGF‐2. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 25, 2018 Category: Dentistry Authors: Shunsuke Fukuba, Tatsuya Akizuki, Shu Hoshi, Takanori Matsuura, Ammar Shujaa Addin, Munehiro Okada, Yasuhiko Tabata, Makoto Matsui, Makoto J. Tabata, Makoto Sugiura ‐Nakazato, Yuichi Izumi Tags: ORIGINAL ARTICLE Source Type: research

The therapeutic potential of regulatory T lymphocytes in periodontitis: A systematic review
This systematic review aimed to: (a) generate a descriptive synthesis of preclinical studies assessing the therapeutic potential of regulatory T lymphocytes (Tregs) to arrest periodontitis, (b) evaluate the methodological heterogeneity of the reviewed animal studies and (c) assess the risk of bias (RoB) of the included studies. The electronic search for animal studies included the MEDLINE, EMBASE, Web of Science and LILACS databases. In addition, a manual search assessed the high ‐ranked scientific journals in “periodontics/immunology” and the references listed in the included studies. There were no language, year or...
Source: Journal of Periodontal Research - November 25, 2018 Category: Dentistry Authors: Emilio Alfredo Cafferata, Alfredo Jerez, Rolando Vernal, Gustavo Monasterio, Nikolaos Pandis, Clovis M. Faggion Tags: REVIEW ARTICLE Source Type: research

Healing differences in narrow diameter implants submitted to immediate and conventional loading in mandibular overdentures: A randomized clinical trial
ConclusionThe IML group presented more favorable PD at all evaluation times; the differences between the other clinical parameters were less systematic. The implant stability and the inflammatory marker concentrations were more stable in the CL group. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 19, 2018 Category: Dentistry Authors: Am ália Machado Bielemann, Raissa Micaella Marcello‐Machado, Alessandra Julie Schuster, Otacílio Luiz Chagas Júnior, Altair Antoninha Del Bel Cury, Fernanda Faot Tags: ORIGINAL ARTICLE Source Type: research

Periodontal condition in Japanese coronary heart disease patients: A comparison between coronary and non ‐coronary heart diseases
ConclusionIncreased periodontal infection was found in Japanese CHD patients compared to non ‐CHD patients. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 18, 2018 Category: Dentistry Authors: Norio Aoyama, Naho Kobayashi, Tomoya Hanatani, Norihiko Ashigaki, Asuka Yoshida, Yuka Shiheido, Hiroki Sato, Chisato Takamura, Shunji Yoshikawa, Katsuhiko Matsuo, Yuichi Izumi, Mitsuaki Isobe Tags: ORIGINAL ARTICLE Source Type: research

Assessment of microRNA ‐144‐5p and its putative targets in inflamed gingiva from chronic periodontitis patients
ConclusionThis re ‐analysis of miRNA signatures has implied the potential regulatory mechanism of miR‐144‐5p and its potential for exploring alternative therapeutic approaches, especially those that use miRNA delivery systems to treat chronic periodontitis. Nevertheless, further study based on larger sample siz e and homogenous cells is needed to reveal the exact roles of miRNAs in chronic periodontitis. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 18, 2018 Category: Dentistry Authors: Jianjia Li, Runting Wang, Yihong Ge, Danhong Chen, Buling Wu, Fuchun Fang Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
Journal of Periodontal Research,Volume 53, Issue 6, Page i-iv, December 2018. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 26, 2018 Category: Dentistry Source Type: research

Protein and mRNA detection of classic cytokines in corresponding samples of serum, gingival tissue and gingival crevicular fluid from subjects with periodontitis
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 26, 2018 Category: Dentistry Authors: Poliana Mendes Duarte, Let ícia Lorenzo Abreu, André Vilela, Magda Feres, Gabriela Giro, Tamires Szeremeske Miranda Source Type: research

Resveratrol attenuates oxidative stress during experimental periodontitis in rats exposed to cigarette smoke inhalation
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 22, 2018 Category: Dentistry Authors: M ônica Grazieli Corrêa, Samir Absy, Howard Tenenbaum, Fernanda Vieira Ribeiro, Fabiano Ribeiro Cirano, Marcio Z. Casati, Suzana Peres Pimentel Source Type: research

Improved RANKL expression and osteoclastogenesis induction of CD27+CD38 − memory B cells: A link between B cells and alveolar bone damage in periodontitis
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 22, 2018 Category: Dentistry Authors: Yakun Han, Ying Jin, Yibin Miao, Tie Shi, Xiaoping Lin Source Type: research

Surface damage of dental implant systems and ions release after exposure to fluoride and hydrogen peroxide
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 22, 2018 Category: Dentistry Authors: Gabriella Pe ñarrieta‐Juanito, Mariane B. Sordi, Bruno Henriques, Marta E. R. Dotto, Wim Teughels, Filipe S. Silva, Ricardo S. Magini, Júlio C. M. Souza Source Type: research

Periodontitis, periodontal inflammation, and mild cognitive impairment: A 5 ‐year cohort study
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 22, 2018 Category: Dentistry Authors: Masanori Iwasaki, Yumi Kimura, Hiroshi Ogawa, Takayuki Yamaga, Toshihiro Ansai, Taizo Wada, Ryota Sakamoto, Yasuko Ishimoto, Michiko Fujisawa, Kiyohito Okumiya, Hideo Miyazaki, Kozo Matsubayashi Source Type: research

Assessment of microRNA ‐146a in generalized aggressive periodontitis and its association with disease severity
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 17, 2018 Category: Dentistry Authors: S. Ghotloo, H. Motedayyen, D. Amani, M. Saffari, M. Sattari Source Type: research

Identification of genetic risk factors of aggressive periodontitis using genomewide association studies in association with those of chronic periodontitis
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 10, 2018 Category: Dentistry Authors: Risa Masumoto, Jirouta Kitagaki, Chiharu Fujihara, Masahiro Matsumoto, Shizuka Miyauchi, Yoshihiro Asano, Atsuko Imai, Kaori Kobayashi, Akihiro Nakaya, Motozo Yamashita, Satoru Yamada, Masahiro Kitamura, Shinya Murakami Source Type: research