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Members in the NewsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Tags: Members in the News Source Type: journals

President's Message: The Surprise Beneath the SurfaceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Powell, V. Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

The Necessity of Considering Serotonin Toxicity as a Differential Diagnosis for NMS-Like SymptomsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Tags: Letter to the Editor Source Type: journals

A Practical Approach for Training Pharmacists and Pharmacy Students to Prevent Disease by ImmunizationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this article is to describe an immunization certification program for pharmacists and pharmacy students based on the requirements of Ohio Law and guidelines of the Centers for Disease Control and Prevention. Program structures for certification programs for pharmacists and pharmacy students are described and include an immunology review, a review of specific immunization medications, a review of aseptic technique, administration techniques, proper disposal procedures, accidental needle sticks, and basic life support training. Teaching methodologies are identified and methods of assessment for mastery of th...
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Powers, M. F., Akala, F. O., Cappelletty, D. M., Shimman, J. J., Kaun, M. A., Capurso, K. A. Tags: Research Source Type: journals

Interventional Case Series: Angiotensin-Converting Enzyme Inhibitor (ACE-I)-Induced Cough: Is Rechallenge With a Second ACE-I Worthwhile?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Angiotensin-converting enzyme inhibitors (ACE-Is) are a cornerstone of therapy with proven morbidity and mortality benefit in many disease states. The unpredictable, bothersome cough that occurs in 15% to 41% of patients oftentimes leads to noncompliance or discontinuation. Management of ACE-I-induced cough remains controversial. The authors’ objective was to determine whether patients experiencing an ACE-I-induced cough could be successfully switched to a different ACE-I without recurrent cough. A total of 10 participants deemed to have ACE-I-induced cough were enrolled in an interventional case series to assess whe...
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Herner, S. J., Kinikar, S. A., Miyashiro, L. A., Billups, S. J. Tags: Adverse Drug Reactions Source Type: journals

Continuing Education: Caring for the Elderly in an Inpatient Setting: Managing Insomnia and PolypharmacyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Tags: Continuing Education Article Source Type: journals

Caring for the Elderly in an Inpatient Setting: Managing Insomnia and PolypharmacyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article addresses these concerns by highlighting key points from the available literature. Insomnia may be a problem in the elderly because of their increased sensitivity to changes in environment among other factors. First, obtain a sleep history and a comprehensive medical and medication history to identify the cause. Next, treat the underlying cause with nonpharmacological interventions to restore restful and qualitative sleep. When nonpharmacological interventions are not successful, pharmacological means are indicated. Remember to start low, go slow, and treat for a short duration of time (less than 4 weeks) to a...
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Kim, J., Tofade, T. S., Peckman, H. Tags: Continuing Education Article Source Type: journals

Psychosis From Anticholinergic Medications Administered at a Smoking Cessation ClinicEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anticholinergic medications are used for a variety of reasons, from their effects on the central nervous system to their effects on the gastrointestinal tract. They are used in the treatment of Parkinson’s disease, vertigo, gastroesophageal reflux disease, and peptic ulcer disease. They have also been used in the treatment of motion sickness. These medications must be used with caution due to their effects on other systems, including the central nervous system. Common central nervous system side effects due to anticholinergic medications include sedation, delirium, amnesia, and in the case of the patient presented in...
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Minton, J. A., Tofade, T. S., Shah, S. A. Tags: Topics in Internal Medicine Source Type: journals

Metabolic and Cardiac Side Effects of Second-generation Antipsychotics: What Every Clinician Should KnowEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article discusses the risk of weight gain, hyperglycemia, hyperlipidemia, hyperprolactinemia, and cardiovascular concerns associated with second-generation antipsychotic agents. It also discusses the proposed mechanisms for each of these adverse effects. Furthermore, it reviews suggested monitoring parameters to help manage cardiovascular disease in this patient population, and to improve the gap that exists between mental health care and physical health care in the schizophrenic population. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Breden, E. L., Liu, M. T., Dean, S. R. Tags: Topics in Internal Medicine Source Type: journals

Hyperglycemia Management in Non-critically Ill Hospitalized PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There is increasing evidence demonstrating negative consequences and poor clinical outcomes associated with untreated hyperglycemia in hospitalized patients. Data in specific patient populations, primarily critically ill patients, demonstrate improved patient outcomes with tight glycemic control. To date, no clear evidence exists to determine optimal glycemic targets in non-critically ill patients; however, experts agree that better glycemic control in hospitalized patients is warranted. Glycemic control is complicated by numerous factors in hospitalized patients including increased circulating stress hormones, changing nu...
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Arnold, L. M., Keller, D. L. Tags: Topics in Internal Medicine Source Type: journals

Recent Advances in PharmacotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article discusses medications by their respective body system. Each review is comprised of an overview of the Food and Drug Administration–approved indication and the drug’s role in treatment of that disease state. Current dosing guidance, clinical efficacy and clinically relevant adverse drug reactions, drug interactions, contraindications, and precautions are also presented. This review is designed to focus on the new molecular entities and biological approvals clinicians may potentially encounter in an internal medicine practice. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Kemp, D. W., Brown, J. N. Tags: Topics in Internal Medicine Source Type: journals

Introduction: Topics in Internal MedicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Tags: Topics in Internal Medicine Source Type: journals

Do You Just Belong?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Authors: Powell, V. Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

ErratumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Tags: Book Review Source Type: journals

Book Review: Medical-Legal Aspects of Alcohol (4th Edition): Edited by James C. Garriott Lawyers & Judges Publishing Company, Inc. 2003. 452 pages. US$81.27. http://www.lawyersandjudges.comEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Authors: Dougherty, P. Tags: Book Review Source Type: journals

Reconstitution of Plenaxis(R) (Abarelix) 100 mg for Injection Is More Effective With a Vortex-Like Mixer Than When Performed ManuallyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abarelix, which is used in the treatment of advanced or metastatic prostate cancer, is supplied in lyophilized (freeze-dried powder) form and needs to be reconstituted to an injectable suspension prior to administration. The advantages of lyophilized forms of medications are their stability and their prolonged shelf-life. Reconstitution to an injectable solution, however, takes time and requires training of the health care professionals who administer these drugs. In addition, inadequate dosing may occur if not all the powder is reconstituted. Development studies of abarelix have shown difficulties with its reconstitution ...
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Authors: Watters, K., Wragg, G., Van Renen, J. Tags: Research Article Source Type: journals

Simvastatin- and Fluvastatin-Associated NightmaresEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The authors present a case of nightmares induced by the 3-hydroxy-3-methylglutaryl coenzyme A (HMGCoA) reductase inhibitors simvastatin and fluvastatin. A 79-year-old Caucasian male initially treated with simvastatin 10 mg every evening developed nightmares after the dose was increased to 40 mg. No relief was provided with a dose reduction to 20 mg, and simvastatin was held. Simvastatin was restarted 7 weeks later at 10 mg, with no complaints of nightmares until the dose was escalated to 20 mg. Simvastatin therapy was subsequently stopped. One month later, fluvastatin 80 mg was initiated and nightmares returned within 3 mo...
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Authors: Wood, R. L., Cummins, D. F. Tags: Adverse Drug Reactions Source Type: journals

Continuing Education Test QuestionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Tags: Continuing Education Article Source Type: journals

Trends in the Treatment of Chronic Hepatitis C Virus InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despite reductions in the incidence of new hepatitis C virus infections, infections from previous decades continue to place a substantial burden on our health care system. Although the course of the disease is highly variable, approximately 20% to 30% of patients develop cirrhosis, end-stage liver disease, or hepatocellular carcinoma. Fortunately, treatment with our current standard of care, peginterferon a and ribavirin, can reduce the complications of chronic liver disease. However, these drugs are associated with significant adverse effects, many patients are ineligible for treatment, and only 50% are cured. Thus, there...
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Authors: Kiser, J. J. Tags: Continuing Education Article Source Type: journals

Nonviral HepatitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic liver diseases are a significant cause of death worldwide. Cirrhosis is most frequently caused by hepatitis C or alcohol abuse, but other nonviral etiologies are now recognized as important contributors to the development of hepatitis. Nonalcoholic fatty liver disease, caused by abnormal accumulation of lipids in hepatocytes, can progress from simple steatosis to necroimflammation and cirrhosis. It is estimated to occur in up to 40% of the general population, and its pathophysiology is closely linked to features of metabolic syndrome. There is currently no proven treatment for nonalcoholic fatty liver disease. Mana...
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Authors: Wilbur, K. Tags: Hepatitis Source Type: journals

Chronic Hepatitis B Infection: Principles of TherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic hepatitis B is a global health concern in many resource-limited settings due to perinatal or pediatric hepatitis B virus transmission. In the United States, pediatric infection has been virtually eliminated due to maternal screening during pregnancy and the availability of an effective vaccine. However, young adults remain an at-risk group for hepatitis B virus infection due to sexual transmission and injection drug use. The frequency of progression from acute hepatitis B virus infection to chronic hepatitis B infection depends on multiple factors, including host immune function and age at time of hepatitis B virus...
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Authors: Scarsi, K. K., Darin, K. M. Tags: Hepatitis Source Type: journals

Introduction: HepatitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - July 21, 2009 Category: Drugs & Pharmacology Authors: Hemstreet, B. A., MacLaren, R. Tags: Hepatitis Source Type: journals

Letter of Duplicate PublicationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

Injuries and the Cost of Falls Among Older Adults--How Pharmacists Can HelpEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fall-related injuries are a serious public health issue among older adults. In addition to having a significant impact on our economy, these injuries are associated with considerable morbidity. Each year, 1 out of every 3 adults aged 65 and older fall; of these adults, 10% to 20% sustain serious injuries such as fractures or head traumas. Such injuries account for about 6% of medical expenditures for adults 65 years and older. Pharmacist interventions can prevent falls, thereby improving the quality of life of these older adults, preserving their independence, and significantly reducing health care costs. (Source: Journal ...
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Authors: Limona, D. Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

New York State Council of Health-system Pharmacists 2009 Poster AbstractsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

Each One Teach OneEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Authors: Powell, V. Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

The Journey--The New BeginningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Authors: Blumenfeld, M. Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

Novel Approaches to the Treatment of Type 2 DiabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The emergence of the glucoregulatory hormone, glucagon-like peptide-1, has expanded our understanding of glucose homeostasis. The glucoregulatory actions of glucagon-like peptide-1 include enhancement of glucose-dependent insulin secretion, suppression of inappropriately elevated glucagon secretion, slowing of gastric emptying, and reduction of food intake. Two approaches have been developed to potentiate the effects of glucagon-like peptide-1 in those with type 2 diabetes. The glucagon-like peptide-1 analogs, such as exenatide, and dipeptidyl peptidase-IV inhibitors, such as sitagliptin, are currently available whereas ot...
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Authors: St. Onge, E. L., Miller, S. A., Taylor, J. R. Tags: Review Article Source Type: journals

Determining Change in Self-Perceived Knowledge and Skills About Disease/ Medication Therapy Management Programs in P3 StudentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The study objectives were to determine a change in the self-perceived knowledge and skills of the third-professional year Doctor of Pharmacy students after taking a course on developing, implementing, and evaluating a disease/medication therapy management program. The study used a cross-sectional before-and-after design in which the data were collected once at the beginning of the course and then upon course completion. A self-administered questionnaire that had 4 sections and 36 questions, focusing on self-perceived knowledge and skills was administered. The data were analyzed using SPSS version 14.0. Descriptive statisti...
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Authors: Pinto, S. L. Tags: Research Article Source Type: journals

Continuing Education Test QuestionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Tags: Continuing Education Article Source Type: journals

Management of Cirrhosis and Associated ComplicationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Liver cirrhosis is the encapsulation or replacement of injured tissue by collagen, resulting in end-stage liver disease and portal hypertension. The consequences of cirrhosis are impaired hepatocyte function, increase intrahepatic circulatory resistance, portal hypertension, and the development of hepatocellular carcinoma. Complications include encephalopathy, coagulopathy, varices, ascites, spontaneous bacterial peritonitis, epatorenal syndrome, and hepatopulmonary syndrome. Managing patients with acute or chronic liver failure is challenging, and liver failure may have profound effects on other organ systems. Most therap...
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Authors: MacLaren, R. Tags: Continuing Education Article Source Type: journals

Drug-Induced Liver Disease and Drug Use Considerations in Liver DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic liver disease encompasses a large number of hepatic disorders. One of the most important etiologies of liver disease is drug-induced liver disease, which is the leading cause of liver failure in patients referred for liver transplantation in the United States. Drug-induced liver disease can present in all forms of acute and chronic liver disease with highly variable clinical presentations. There is no effective treatment for most drug-induced liver disease and the recognition and prevention of drug-induced liver disease remain the most important management strategy. Drug dosing in patients with liver disease repres...
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Authors: Kim, J. W., Phongsamran, P. V. Tags: Hepatology Source Type: journals

Introduction: HepatologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 20, 2009 Category: Drugs & Pharmacology Authors: Hemstreet, B. A., MacLaren, R. Tags: Hepatology Source Type: journals

College of Psychiatric and Neurologic Pharmacists 2009 Poster AbstractsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Tags: CPNP Poster Abstracts Source Type: journals

Introduction to the College of Psychiatric and Neurologic Pharmacists 2009 Poster AbstractsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Ellingrod, V. Tags: CPNP Poster Abstracts Source Type: journals

Dispensary to Dispensary--The Critical Progression for Health System PharmacyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Blumenfeld, M. Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

Successful Clozapine Rechallenge Following Surgical Repair of a Bowel ObstructionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
As a consequence of its significant anticholinergic properties, constipation is a commonly reported adverse event in patients treated with clozapine. This side effect is often self-limiting and can be managed with high-fiber diets, adequate hydration, and standard over-the-counter and prescription preparations. However, severe cases of constipation can become more serious and may lead to intestinal obstruction, intestinal perforation, fecal impaction, or paralytic ileus. In this particular case, we report on a 44-year-old woman who presented with a suspected clozapine-induced bowel obstruction. Following total abdominal co...
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Dahmen, M. M., Stoner, S. C., Khan, R. Tags: Adverse Drug Reaction Article Source Type: journals

Continuing Education Test QuestionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Tags: Continuing Education Article Source Type: journals

The Benefit and Risk of Antidiabetic Agents Used in Patients With Heart DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the published evidence assessing the benefits and risk of antidiabetic agents as related to cardiovascular outcomes. Current literature revealed that metformin and -glucosidase inhibitors are the two agents that have not been associated with any harm in diabetic patients in terms of cardiovascular events. Clinical studies have demonstrated controversial results in the use of insulin, sulfonylureas, and thiazolidinediones and cardiovascular outcomes. However, the results may be affected by other unknown confounders, the comparative agents, and the degree of control of other cardiovascular risk factors. ...
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Cheng, J. W. M., Bhatt, S. H., Goldman-Levine, J. D. Tags: Continuing Education Article Source Type: journals

Pediatric Pulmonary Hypertension: A Pharmacotherapeutic ReviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pulmonary hypertension in children is a disorder associated with increased pulmonary vascular resistance and arterial pressure, decreased cardiac output, and right-sided cardiac dysfunction that is caused by numerous etiologies. Although treatment will vary with underlying cause, pharmacological treatment has historically included inhaled nitric oxide and prostacyclin analogues. Over the past several years new agents have been added to the treatment armamentarium, including phosphodiesterase V inhibitors (eg sildenafil) and endothelin antagonists (eg bosentan). Further, more agents are currently under investigation for pul...
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Pesaturo, K. A., Johnson, P. N., Ramsey, E. Z. Tags: Cardiovascular Therapeutics Source Type: journals

Prasugrel: A New Thienopyridine InhibitorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this review is to report the pharmacologic and pharmacokinetic properties of prasugrel, the potential advantages and disadvantages over the other agent in its class, clopidogrel, and the clinical data establishing its efficacy in the management of patients with acute coronary syndromes receiving stent implantation. A MEDLINE (1966 to May 2008) search using the key word prasugrel was performed to identify pertinent literature. Additional references were selected from the bibliographies of the articles cited. Searches were not limited by time or human subject. Preclinical studies evaluating the pharmacologic...
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Veverka, A., Hammer, J. M. Tags: Cardiovascular Therapeutics Source Type: journals

Heparin-induced Thrombocytopenia: Pathophysiology, Diagnosis, and Review of PharmacotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article will review the pathophysiology, clinical presentation, complications, diagnosis, and pharmacotherapy management of heparin-induced thrombocytopenia. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Kanaan, A. O., Al-Homsi, A. S. Tags: Cardiovascular Therapeutics Source Type: journals

Macrovascular Complications of Diabetes MellitusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Adults with diabetes mellitus frequently develop macrovascular complications. Vascular disease is a frequent cause of morbidity and mortality among patients with diabetes. Diabetes and vascular diseases remain among the most common causes of death in the United States. A number of clinical trials and practice guidelines have been published addressing the management of macrovascular complications. The cornerstone of preventing or delaying the progression of macrovascular complications of diabetes is aggressive management of hypertension and cholesterol. Angiotensin-converting enzyme inhibitors have proven effective in manag...
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Nuzum, D. S., Merz, T. Tags: Cardiovascular Therapeutics Source Type: journals

Introduction: Cardiovascular TherapeuticsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 30, 2009 Category: Drugs & Pharmacology Authors: Olin, J. L., Spooner, L. M. Tags: Cardiovascular Therapeutics Source Type: journals

When Opportunity KnocksEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - January 26, 2009 Category: Drugs & Pharmacology Authors: Zammit, K. Tags: New York State Council of Health-system Pharmacists Section Source Type: journals

The Administration of rt-PA (Activase(R)) for the Treatment of Empyema in an Adult PatientEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The administration of various fibrinolytic agents for the treatment of empyema has been reported in past studies. Most of the current literature has shown favorable outcomes in terms of increased tube drainage, improved chest radiography, and reduction in surgical intervention. However, a randomized controlled trial that compared streptokinase to placebo showed no significant reduction in mortality. To date, there have been no randomized controlled trials evaluating the safety, efficacy, and administration of recombinant tissue plasminogen activator for the treatment of empyema in the adult population. The authors report t...
Source: Journal of Pharmacy Practice - January 26, 2009 Category: Drugs & Pharmacology Authors: Emerson, C. R., Bercume, C. M., Antonopoulos, M. S., Marzella, N. Tags: Case Report Source Type: journals

Continuing Education Test QuestionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - January 26, 2009 Category: Drugs & Pharmacology Tags: Continuing Education Article Source Type: journals

Gout and Hyperuricemia: New Guidelines and TreatmentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Gout is the most common inflammatory arthritis in western countries and the incidence is increasing. Additionally, evidence now exists that cases of severe, refractory gout seem to be increasing. The management of gout and hyperuricemia has remained largely unchanged for decades and includes antiinflammatories used initially for acute attacks and primarily allopurinol to prevent future attacks. Evidence-based guidance for the management of gout and hyperuricemia has been plagued by a lack of randomized, controlled studies and the lack of new medications. Recently evidence-based guidelines by the European League Against Rhe...
Source: Journal of Pharmacy Practice - January 26, 2009 Category: Drugs & Pharmacology Authors: Wall, G. C., Cooper, S. A. Tags: Continuing Education Article Source Type: journals

Psoriatic Arthritis: A ReviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Psoriatic arthritis (PsA) is a seronegative inflammatory spondyloarthropathy occurring in individuals with psoriasis. Psoriasis precedes joint disease in approximately 80% of PsA cases. The clinical course of PsA varies from mild arthritis to a severe, debilitating erosive arthropathy that affects functional capacity and quality of life of patients. The incidence of PsA is gender neutral, but a significant genetic component exists. Hallmark clinical features include dystrophic nail changes in the fingers or toes, dactylitis, and enthesitis. Many drugs indicated for use in rheumatoid arthritis have been found useful in the ...
Source: Journal of Pharmacy Practice - January 26, 2009 Category: Drugs & Pharmacology Authors: Eroschenko, K., Cleveland, K. W., Gunter, K. Tags: Rheumatology Source Type: journals

Osteoarthritis: An Update on Data Currently Reshaping PracticeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Osteoarthritis is common, has considerable health consequences, and will affect increasing numbers of persons in coming years. Nonpharmacological interventions are of paramount importance in achieving adequate symptom control. Acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) play a pivotal role in osteoarthritis pharmacotherapy. Acetaminophen, due to its safety profile, should be adequately trialed before resorting to NSAIDs. NSAIDs and celecoxib, a selective inhibitor of cyclooxygenase-2, should be selected thoughtfully so as to balance the likelihood of treatment success with gastrointestinal bleeding and ...
Source: Journal of Pharmacy Practice - January 26, 2009 Category: Drugs & Pharmacology Authors: Epstein, B. J., Taylor, J. R. Tags: Rheumatology Source Type: journals