Journal of the American College of Cardiology: Cardiovascular Interventions
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Correction
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Tags: Correction Source Type: journals
Translational Research: Then and Now
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: King, S. B. Tags: Editor's Page Source Type: journals
Reply
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Reed, M., Meier, P., Gurm, H. S. Tags: Letter to the Editor Source Type: journals
The Relative Renal Safety of Iodixanol Compared With Low-Osmolar Contrast Media
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Cantor, E., Lim, L. Tags: Letter to the Editor Source Type: journals
European Society of Cardiology Congress 2009: Update in Interventional Cardiology
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: George, J. C., Dangas, G. D. Tags: ACC Interventional Scientific Council: News and Views Source Type: journals
Successful Coronary Angioplasty Via the Radial Approach After Sealing a Radial Perforation
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Rigatelli, G., Dell'Avvocata, F., Ronco, F., Doganov, A. Tags: Images in Intervention Source Type: journals
Irrelevance of the Chromosome 9p21.3 Locus for Acute Cardiovascular Events and Restenosis
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Horne, B. D., Anderson, J. L. Tags: Editorial Comment Source Type: journals
No Association of Chromosome 9p21.3 Variation With Clinical and Angiographic Outcomes After Placement of Drug-Eluting Stents
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Conclusions
Specific polymorphisms in the chromosome 9p21.3 region that were shown to be associated with coronary heart disease in genomewide analyses were not related to the clinical and angiographic outcomes after the placement of drug-eluting stents in coronary arteries. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Hoppmann, P., Erl, A., Turk, S., Tiroch, K., Mehilli, J., Schomig, A., Kastrati, A., Koch, W. Tags: Clinical Research Source Type: journals
Long-Term Risk of Adverse Outcomes and New Malignancies in Patients Treated With Oral Sirolimus for Prevention of Restenosis
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Conclusions
The benefit in the reduced need for repeat intervention observed at 1 year with high-dose oral sirolimus therapy was attenuated over 4 years. Moreover, this regimen was associated with numerical yet not a significant increase in newly diagnosed malignancies without augmenting the malignancy-induced risk of death. (Oral Sirolimus for In-Stent Restenosis [OSIRUS] trial; NCT00859183) (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Kufner, S., Hausleiter, J., Ndrepepa, G., Schulz, S., Bruskina, O., Byrne, R. A., Fusaro, M., Kastrati, A., Schomig, A., Mehilli, J., for the OSIRIS Trial Investigators Tags: Clinical Research Source Type: journals
The Efficacy of a Bilateral Approach for Treating Lesions With Chronic Total Occlusions: The CART (Controlled Antegrade and Retrograde subintimal Tracking) Registry
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Conclusions
A bilateral approach for CTO lesions using the CART technique is feasible, safe, and has a higher success rate than previous approaches. These results indicate that a bilateral technique can solve a major dilemma that commonly affects CTO procedures. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Kimura, M., Katoh, O., Tsuchikane, E., Nasu, K., Kinoshita, Y., Ehara, M., Terashima, M., Matsuo, H., Matsubara, T., Asakura, K., Asakura, Y., Nakamura, S., Oida, A., Takase, S., Reifart, N., Di Mario, C., Suzuki, T. Tags: Clinical Research Source Type: journals
Evaluation of the Effect of a Concurrent Chronic Total Occlusion on Long-Term Mortality and Left Ventricular Function in Patients After Primary Percutaneous Coronary Intervention
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Conclusions
The presence of a CTO and not MVD alone is associated with long-term mortality even when early deaths are excluded from analysis. The presence of a CTO is associated with reduced LVEF and further deterioration of LVEF. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Claessen, B. E.P.M., van der Schaaf, R. J., Verouden, N. J., Stegenga, N. K., Engstrom, A. E., Sjauw, K. D., Kikkert, W. J., Vis, M. M., Baan, J., Koch, K. T., de Winter, R. J., Tijssen, J. G.P., Piek, J. J., Henriques, J. P.S. Tags: Clinical Research Source Type: journals
In Search of an Algorithm to Prevent Acute Kidney Injury
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Dauerman, H. L. Tags: Editorial Comment Source Type: journals
Sodium Bicarbonate Plus N-Acetylcysteine Prophylaxis: A Meta-Analysis
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Conclusions
Combination prophylaxis with NAC and NaHCO3 substantially reduced the occurrence of contrast-induced AKI overall but not dialysis-dependent renal failure. Combination prophylaxis should be incorporated for all high-risk patients (emergent cases or patients with chronic kidney disease) and should be strongly considered for all interventional radio-contrast procedures. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brown, J. R., Block, C. A., Malenka, D. J., O'Connor, G. T., Schoolwerth, A. C., Thompson, C. A. Tags: Clinical Research Source Type: journals
Are Our Patients Better Off With Drug-Eluting Stents in Saphenous Vein Grafts?
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Douglas, J. S. Tags: Editorial Comment Source Type: journals
Outcomes With Drug-Eluting Versus Bare-Metal Stents in Saphenous Vein Graft Intervention: Results From the STENT (Strategic Transcatheter Evaluation of New Therapies) Group
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Conclusions
Treatment of SVG lesions with DES vs. BMS is effective in reducing TVR at 9 months, although most of this advantage is lost at 2 years. The DES seem safe with less death or myocardial infarction, although selection bias might have affected these results. Our data suggest that DES might have short-term advantages over BMS in SVG lesions with diameter <3.5 mm. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brodie, B. R., Wilson, H., Stuckey, T., Nussbaum, M., Laurent, S., Bradshaw, B., Humphrey, A., Metzger, C., Hermiller, J., Krainin, F., Juk, S., Cheek, B., Duffy, P., Simonton, C. A., for the STENT Group Tags: Clinical Research Source Type: journals
The Worry About Clopidogrel "Nonresponsiveness": Identification and Treatment in the Post-Percutaneous Coronary Intervention Patient
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Gurbel, P. A., Tantry, U. S., Shuldiner, A. R. Tags: Editorial Comment Source Type: journals
Pharmacogenetic Testing for Clopidogrel Using the Rapid INFINITI Analyzer: A Dose-Escalation Study
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Conclusions
Increasing the dose of clopidogrel in patients with nonresponder polymorphisms can increase antiplatelet response. Personalizing clopidogrel dosing using pharmacogenomics may be an effective method of optimizing treatment. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Gladding, P., White, H., Voss, J., Ormiston, J., Stewart, J., Ruygrok, P., Bvaldivia, B., Baak, R., White, C., Webster, M. Tags: Clinical Research Source Type: journals
Antithrombin Therapy for Elective Percutaneous Coronary Intervention: Which Agent to Use? Does It Matter?
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brener, S. J. Tags: Editorial Comment Source Type: journals
Enoxaparin Versus Unfractionated Heparin in Elective Percutaneous Coronary Intervention: 1-Year Results From the STEEPLE (SafeTy and Efficacy of Enoxaparin in Percutaneous coronary intervention patients, an internationaL randomized Evaluation) Trial
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Conclusions
The 1-year mortality rates were low and comparable between patients receiving enoxaparin and UFH during elective PCI. Periprocedural ischemic or bleeding events were the strongest independent predictors of 1-year mortality. (The STEEPLE Trial; NCT00077844) (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Montalescot, G., Gallo, R., White, H. D., Cohen, M., Steg, Ph. G., Aylward, P. E.G., Bode, C., Chiariello, M., King, S. B., Harrington, R. A., Desmet, W. J., Macaya, C., Steinhubl, S. R., for the STEEPLE Investigators Tags: Clinical Research Source Type: journals
Prognostic Impact of Periprocedural Bleeding and Myocardial Infarction After Percutaneous Coronary Intervention in Unselected Patients: Results From the EVENT (Evaluation of Drug-Eluting Stents and Ischemic Events) Registry
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Conclusions
Among unselected PCI patients, both post-PCI bleeding and pMI are independently associated with increased 1-year mortality. Continued efforts to reduce these complications after PCI are warranted. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Lindsey, J. B., Marso, S. P., Pencina, M., Stolker, J. M., Kennedy, K. F., Rihal, C., Barsness, G., Piana, R. N., Goldberg, S. L., Cutlip, D. E., Kleiman, N. S., Cohen, D. J., on behalf of the EVENT Registry Investigators Tags: Clinical Research Source Type: journals
Vascular Dysfunction of Brachial Artery After Transradial Access for Coronary Catheterization: Impact of Smoking and Catheter Changes
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Conclusions
Transradial catheterization not only leads to dysfunction of the RA but also the upstream BA, which is more severe and sustained in smokers and with increasing numbers of catheters. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Heiss, C., Balzer, J., Hauffe, T., Hamada, S., Stegemann, E., Koeppel, T., Merx, M. W., Rassaf, T., Kelm, M., Lauer, T. Tags: Mini-Focus Issue: Transradial Approach Source Type: journals
Transradial Access: Just Do It!
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Mann, T. Tags: Editorial Comment Source Type: journals
Mechanism and Predictors of Failed Transradial Approach for Percutaneous Coronary Interventions
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Conclusions
Transradial approach PCI can be performed by low-to-intermediate volume operators with standard equipment with a low failure rate. Age >75 years, prior coronary artery bypass graft surgery, and short stature are independent predictors of TR-PCI failure. Appropriate patient selection and careful risk assessment are needed to maximize benefits offered by TR-PCI. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Dehghani, P., Mohammad, A., Bajaj, R., Hong, T., Suen, C. M., Sharieff, W., Chisholm, R. J., Kutryk, M. J.B., Fam, N. P., Cheema, A. N. Tags: Mini-Focus Issue: Transradial Approach Source Type: journals
Cardiac Catheterization on the Road Less Traveled: Navigating the Radial Versus Femoral Debate
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Kern, M. J. Tags: Editorial Comment Source Type: journals
A Randomized Comparison of Transradial Versus Transfemoral Approach for Coronary Angiography and Angioplasty
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Conclusions
The findings of the present study show that transradial coronary angiography and angioplasty are safe, feasible, and effective with similar results to those of the transfemoral approach. However, procedural duration and radiation exposure are higher using the transradial access. In contrast to the transfemoral route, the rate of major vascular complications was negligible using the transradial approach. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brueck, M., Bandorski, D., Kramer, W., Wieczorek, M., Holtgen, R., Tillmanns, H. Tags: Clinical Research Source Type: journals
Intracoronary Optical Coherence Tomography: A Comprehensive Review: Clinical and Research Applications
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Cardiovascular optical coherence tomography (OCT) is a catheter-based invasive imaging system. Using light rather than ultrasound, OCT produces high-resolution in vivo images of coronary arteries and deployed stents. This comprehensive review will assist practicing interventional cardiologists in understanding the technical aspects of OCT based upon the physics of light and will also highlight the emerging research and clinical applications of OCT. Semi-automated imaging analyses of OCT systems permit accurate measurements of luminal architecture and provide insights regarding stent apposition, overlap, neointimal thickeni...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Bezerra, H. G., Costa, M. A., Guagliumi, G., Rollins, A. M., Simon, D. I. Tags: State-of-the-Art Paper Source Type: journals
Correction
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Tags: Correction Source Type: journals
"If You Have a Heart Attack, Just Cough"
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: King, S. B. Tags: Editor's Page Source Type: journals
Cocaine-Induced Coronary Artery Dissection
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Ijsselmuiden, A., Verheye, S. Tags: Images in Intervention Source Type: journals
Health Care Reform Bill H. R. 3200--America's Affordable Health Choices Act: What Is Missing?
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The House of Representatives recently introduced its Health Care Reform Bill that is labeled America's Affordable Health Choices Act. It seeks to provide affordable health care for all Americans and curb medical expense growth by offering coverage and choice, affordability, shared responsibility, prevention and wellness measures, and workforce investments. However, it fails to address the escalating threat of medical liability, the lack of patient accountability, and the absence of outcome measures in health care delivery that may jeopardize the cost and quality of accessible medical care. (Source: Journal of the American ...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: George, J. C., Bass, T. A. Tags: ACC Interventional Scientific Council: News and Views Source Type: journals
Do We Really Understand Pimecrolimus?
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Vorpahl, M., Finn, A. V., Nakano, M., Virmani, R. Tags: Editorial Comment Source Type: journals
Feasibility, Safety, and Efficacy of a Novel Polymeric Pimecrolimus-Eluting Stent: Traditional Pre-Clinical Safety End Points Failed to Predict 6-Month Clinical Angiographic Results
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Conclusions
Pimecrolimus-eluting stents induced an exaggerated neointimal hyperplasia at 6 months in comparison with historical controls. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Ormiston, J. A., Webster, M. W.I., Schwartz, R. S., Gladding, P., Stewart, J. T., Kay, I. P., Ruygrok, P. N., Hatrick, R. Tags: Clinical Research Source Type: journals
Bone Marrow-Derived B Cells Preserve Ventricular Function After Acute Myocardial Infarction
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Conclusions
Intramyocardial injection of B cells into early post-ischemic myocardium preserved cardiac function by cardiomyocyte salvage. Other BM MNC subtypes were either ineffective or suppressed cardioprotection conferred by an enriched B cell population. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Goodchild, T. T., Robinson, K. A., Pang, W., Tondato, F., Cui, J., Arrington, J., Godwin, L., Ungs, M., Carlesso, N., Weich, N., Poznansky, M. C., Chronos, N. A.F. Tags: Clinical Research Source Type: journals
Intravascular Ultrasound Assessment of the Incidence and Predictors of Edge Dissections After Drug-Eluting Stent Implantation
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Conclusions
IVUS identified edge dissections after 9.2% of DES implantations. Residual plaque eccentricity, lumen-to-stent-edge-area ratio, and stent edge symmetry predicted coronary stent edge dissections. Dissections in less diseased reference segments more often evolved into an intramural hematoma. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Liu, X., Tsujita, K., Maehara, A., Mintz, G. S., Weisz, G., Dangas, G. D., Lansky, A. J., Kreps, E. M., Rabbani, L. E., Collins, M., Stone, G. W., Moses, J. W., Mehran, R., Leon, M. B. Tags: Clinical Research Source Type: journals
Optimal Stent Expansion and Complete Neointimal Coverage: Does This Association Make Sense?
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Mintz, G. S., Choi, S.-Y. Tags: Editorial Comment Source Type: journals
Optimal Stent-Sizing With Intravascular Ultrasound Contributes to Complete Neointimal Coverage After Sirolimus-Eluting Stent Implantation Assessed by Angioscopy
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Conclusions
Adequate stent sizing relative to the vessel size might contribute to the angioscopically complete neointimal coverage after SES implantation. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Sera, F., Awata, M., Uematsu, M., Kotani, J.-i., Nanto, S., Nagata, S. Tags: Clinical Research Source Type: journals
A Generation 2.5 Drug-Eluting Stent?
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Ellis, S. G. Tags: Editorial Comment Source Type: journals
Clinical and Angiographic Results With the Next-Generation Resolute Stent System: A Prospective, Multicenter, First-in-Human Trial
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Conclusions
In this feasibility study, the Resolute stent demonstrated low in-stent late lumen loss, minimal neointimal hyperplastic ingrowth, low TLR, no stent thrombosis, and acceptable TVF and MACE. (The RESOLUTE Clinical Trial; NCT00248079) (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Meredith, I. T., Worthley, S., Whitbourn, R., Walters, D. L., McClean, D., Horrigan, M., Popma, J. J., Cutlip, D. E., DePaoli, A., Negoita, M., Fitzgerald, P. J., for the RESOLUTE Investigators Tags: Clinical Research Source Type: journals
Clinical and Angiographic Outcomes in Diabetics From the ENDEAVOR IV Trial: Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease
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Conclusions
One-year clinical outcomes were similar among DM patients treated with ZES and PES in the ENDEAVOR IV trial. These findings parallel the overall trial results, which demonstrated similar efficacy and safety of ZES and PES for single de novo coronary lesions. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Kirtane, A. J., Patel, R., O'Shaughnessy, C., Overlie, P., McLaurin, B., Solomon, S., Mauri, L., Fitzgerald, P., Popma, J. J., Kandzari, D. E., Leon, M. B. Tags: Clinical Research Source Type: journals
Diabetes Mellitus Does Not Unsweeten Left Main Intervention
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Williams, D. O., Abbott, J. D. Tags: Editorial Comment Source Type: journals
Impact of Diabetes Mellitus on the Treatment Effect of Percutaneous or Surgical Revascularization for Patients With Unprotected Left Main Coronary Artery Disease: A Subgroup Analysis of the MAIN-COMPARE Study
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Conclusions
The prognostic impact of diabetes on long-term treatment with DES or CABG for patients with unprotected LMCA disease was minimal. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Kim, W.-J., Park, D.-W., Yun, S.-C., Lee, J.-Y., Lee, S.-W., Kim, Y.-H., Lee, C. W., Park, S.-W., Park, S.-J. Tags: Clinical Research Source Type: journals
Non-ST-Segment Elevation Myocardial Infarction Treated at Hospitals With and Without On-Site Cardiac Surgery: What Is the Important Point?
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Dehmer, G. J., Brindis, R. G. Tags: Editorial Comment Source Type: journals
Outcomes Among Patients With Non-ST-Segment Elevation Myocardial Infarction Presenting to Interventional Hospitals With and Without On-Site Cardiac Surgery
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Conclusions
NSTEMI patients presenting to No-OHS hospitals have significantly higher mortality. This appears to be due to both modifiable (lower use of guideline-recommended medications) and nonmodifiable factors (hospital size, myocardial infarction volume). In a propensity-matched analysis of patients undergoing PCI for NSTEMI, there was no significant difference in mortality. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Pride, Y. B., Canto, J. G., Frederick, P. D., Gibson, C. M., for the NRMI Investigators Tags: Clinical Research Source Type: journals
Randomized Comparison of Primary Percutaneous Coronary Intervention With Combined Proximal Embolic Protection and Thrombus Aspiration Versus Primary Percutaneous Coronary Intervention Alone in ST-Segment Elevation Myocardial Infarction: The PREPARE (PRoximal Embolic Protection in Acute myocardial infarction and Resolution of ST-Elevation) Study
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Conclusions
There was no significant difference in complete STR at 60 min in this proof-of-concept study. However, we observed a significant difference in immediate complete STR in Proxis-treated patients, better STR at later time points, and a reduction of electrocardiogram injury current over time, compared with control patients. The results suggest that primary PCI with the Proxis system may lead to better immediate microvascular flow in ST-segment elevation myocardial infarction patients. (The PREPARE Study; ISRCTN71104460) (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Haeck, J. D.E., Koch, K. T., Bilodeau, L., Van der Schaaf, R. J., Henriques, J. P.S., Vis, M. M., Baan, J., Van der Wal, A. C., Piek, J. J., Tijssen, J. G.P., Krucoff, M. W., De Winter, R. J. Tags: Clinical Research Source Type: journals
The Ideal Reperfusion Strategy for the ST-Segment Elevation Myocardial Infarction Patient With Expected Delay to Percutaneous Coronary Intervention: Paradise Lost or Paradise Renamed?
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Henry, T. D., Larson, D. M. Tags: Editorial Comment Source Type: journals
The Impact of Place of Enrollment and Delay to Reperfusion on 90-Day Post-Infarction Mortality in the ASSENT-4 PCI Trial: Assessment of the Safety and Efficacy of a New Treatment Strategy With Percutaneous Coronary Intervention
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Conclusions
Few patients fit the target population, long delays to PCI for whom facilitated PCI was designed. Patients treated early after pain onset in the PreH setting do well after a facilitated approach. Despite limitations of post hoc subgroup analysis, these observations suggest caution in extrapolating the results of the ASSENT-4 trial to the "real world" where many patients might have potentially short pain-to-fibrinolysis time but are facing a long transport time to primary PCI. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Ross, A. M., Huber, K., Zeymer, U., Armstrong, P. W., Granger, C. B., Goldstein, P., Bogaerts, K., Van de Werf, F. Tags: Clinical Research Source Type: journals
Benefit of Facilitated Percutaneous Coronary Intervention in High-Risk ST-Segment Elevation Myocardial Infarction Patients Presenting to Nonpercutaneous Coronary Intervention Hospitals
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Conclusions
Facilitation of PCI with a combination of abciximab and half-dose reteplase improved survival at 1 year in high-risk patients presenting to a spoke hospital with symptom-to-randomization time ≤4 h. Further prospective study of facilitated PCI in this subgroup of patients is warranted. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Herrmann, H. C., Lu, J., Brodie, B. R., Armstrong, P. W., Montalescot, G., Betriu, A., Neuman, F.-J., Effron, M. B., Barnathan, E. S., Topol, E. J., Ellis, S. G., for the FINESSE Investigators Tags: Clinical Research Source Type: journals
1-Year Survival in a Randomized Trial of Facilitated Reperfusion: Results From the FINESSE (Facilitated Intervention With Enhanced Reperfusion Speed to Stop Events) Trial
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Conclusions
These results suggest that widespread utilization of the facilitated approaches tested cannot be justified, but that high-risk patient groups such as patients with anterior MI may deserve further study. (The FINESSE trial; NCT00046228) (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Ellis, S. G., Tendera, M., de Belder, M. A., van Boven, A. J., Widimsky, P., Andersen, H. R., Betriu, A., Savonitto, S., Adamus, J., Peruga, J. Z., Hamankiewicz, M., Pluta, W., Oldroyd, K., Ecollan, P., Janssens, L., Armstrong, P., Brodie, B. R., Herrmann Tags: Clinical Research Source Type: journals
Systems of Care for ST-Segment Elevation Myocardial Infarction: Impact of Different Models on Clinical Outcomes
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ST-segment elevation myocardial infarction (STEMI) is one of the greatest medical emergencies, for which organization of care has a determinant impact on patient outcomes. The purpose of this paper is to review systems of care for STEMI patients. Although primary percutaneous coronary intervention (PCI) is the preferred option for patients with STEMI, offering easy and emergent access to this procedure often remains difficult because of geographic and diverse structural difficulties. intravenous fibrinolysis, especially when administered early after symptom onset and as part of a pharmacoinvasive strategy (i.e., followed b...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Danchin, N. Tags: State-of-the-Art Paper Source Type: journals
Is the Pen Mightier Than the Stent?
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(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - September 20, 2009 Category: Cardiovascular & Thoracic Surgery Authors: King, S. B. Tags: Editor's Page Source Type: journals
