Prof Mahesh Chandra Vaidya
Publication date: December 2018Source: Journal of the Anatomical Society of India, Volume 67, Issue 2Author(s): (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - December 7, 2018 Category: Anatomy Source Type: research

Effect of stress induced by expsoure to short and long term foot shock on liver, spleen and kidney in aged mice
DiscussionThus it is concluded from the entire study that long term stress causes degeneration in hepatic cells, infiltration in liver, degeneration of glomerulus, bowman’s capsule, convoluted tubules in kidney which finally leading to both hepato-toxicity and nephro-toxicity. In spleen long term stress alters the immune response in Old age Albino Mice by inducing morphology changes, explaining in part the indicating impaired immunity that develops in organisms that are exposed to chronic stress. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - November 23, 2018 Category: Anatomy Source Type: research

Role of genomic changes in chromosome 17 and p53 gene in oral squamous cell carcinoma patients by Flouroscence in situ hybridization in Indian population
This study was performed retrospectively on 30 cases diagnosed with OSCC through FISH technique. Molecular cytogenetic techniques, using fluorescence in situ hybridization with chromosome-specific DNA probes, facilitate the confirmation of presumed chromosomal aberrations with high sensitivity and specificity.ResultsOut of 30 cases 29 represent molecular alteration. About 70% of cases presented chromosome 17 polysomy and only 20% of cases had chromosome 17 monosomy. 58% of samples revealed p53 gene amplification and 37% of them showed p53 deletion.DiscussionHigh frequency of correlation between molecular changes in chromos...
Source: Journal of the Anatomical Society of India - November 23, 2018 Category: Anatomy Source Type: research

A Morphological Study of Branches of External Carotid Artery in Adult Human Cadavers
ConclusionKnowledge about the variations of origin of branches of external carotid artery is important for surgeons performing head and neck surgeries. It is also helpful for radiologists for diagnostic imaging of vascular lesions and for interventional procedures. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - November 18, 2018 Category: Anatomy Source Type: research

Morphometric Analysis of Lateral and Third Ventricles by Computerized Tomography for Early Diagnosis of Hydrocephalus
This study aims to highlight the reference range values for lateral and third ventricles of brain for easy diagnosis and management of hydrocephalic patients.Material and Methods: We calculated the frontal horn ratio(FHR), bi- caudate ratio(BCR), Evan’s ratio(ER), cella media ratio(CMR), bi-frontal index(BFI), bi- occipital index(BOI), third ventricle width(TVW), third ventricle sylvian fissure ratio index (TSFI), and third ventricle ratio (TVR) in 120 apparently normal CT-Head images and forty hydrocephalic images by taking linear measurements withdicom image software. Descriptive statistics –mean, standard deviation,...
Source: Journal of the Anatomical Society of India - November 16, 2018 Category: Anatomy Source Type: research

Role of sVEGFR (sFlt-1) in inducing endoplasmic reticulum stress in trophoblast cells and its status in Preeclampsia
ConclusionWe reported significant ER stress in the placental cells (BeWo Cells) (in vitro) when exposed to normotensive sera with recombinant sFlt-1 and also when treated with recombinant sFlt-1 alone. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - November 16, 2018 Category: Anatomy Source Type: research

Analyses of genomic changes in chromosome 17 and P53 gene in oral squamous cell carcinoma patients
This study was performed retrospectively on 30 cases diagnosed with OSCC through FISH technique. Molecular cytogenetic techniques, using fluorescence in situ hybridization with chromosome-specific DNA probes, facilitate the confirmation of presumed chromosomal aberrations with high sensitivity and specificity.ResultsOut of 30 cases 29 represent molecular alteration. About 70 % of cases presented chromosome 17 polysomy and only 20% of cases had chromosome 17 monosomy. 58% of samples revealed p53 gene amplification and 37% of them p53 deletion.DiscussionHigh frequency of correlation between molecular changes in chromosome 17...
Source: Journal of the Anatomical Society of India - November 16, 2018 Category: Anatomy Source Type: research

Off-line Virtual Microscopy in Teaching Histology to the Undergraduate Medical Students: Do the Benefits Correlate with the Learning Style Preferences?
DiscussionVirtual slides, when used in teaching histology as an adjunct to conventional microscopy, positively influenced the performance of the students irrespective of their learning style preferences. Offline virtual slides can be a via-media approach for using virtual microscopy in the institutions lacking in high-end infrastructure. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - November 15, 2018 Category: Anatomy Source Type: research

The effects of the communicating branch between medial and lateral plantar nerves on the innervations of the foot lumbrical muscles
In this study, the number and localization of the communicating branch on the innervations of foot muscles were evaluated to open a new sight considering the innervations of lumbrical muscles.Materials and Methods30 formalin-fixed feet (15 right – 15 left feet), with an average age of 76 from the inventory of Trakya and Mersin University Anatomy Departments in 2015 were dissected. The innervations of the lumbricals and the communicating branches were revealed and then photographed.ResultsIn all feet, first lumbricals were observed to be innervated by MPN, while the remaining muscles were innervated by deep branches of LP...
Source: Journal of the Anatomical Society of India - November 14, 2018 Category: Anatomy Source Type: research

Vacuum Phenomenon in Multiple Joints; Prevalence and association with age and gender
DiscussionVP may be detected as an incidental finding in various joints at the same time. Therefore, its presence may not have any clinical relevance. Examination technique, joint position and patient population may affect the PRVP in the joints. Knowledge of this anatomical phenomenon may prevent faulty diagnosis of joint pathology and prevent suboptimal treatment of patients. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - November 14, 2018 Category: Anatomy Source Type: research

Effect of stress induced by expsoure to short and long term foot shock on liver,spleen and kidney in aged mice
DISCUSSIONThus it is concluded from the entire study that long term stress causes degeneration in hepatic cells, infiltration in liver, degeneration of glomerulus, bowman’s capsule, convoluted tubules in kidney which finally leading to both hepato-toxicity and nephro-toxicity. In spleen long term stress alters the immune response in Old age Albino Mice by inducing morphology changes, explaining in part the indicating impaired immunity that develops in organisms that are exposed to chronic stress. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - November 14, 2018 Category: Anatomy Source Type: research

An anatomical study of the caprine posterior cruciate ligament
DiscussionQuantitative data on the size and morphology of the PCL anatomy were obtained on caprine knees, which provides guidance for future translational research on the sheep model to improve surgical techniques for surgical reconstruction and other PCL treatments. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - November 11, 2018 Category: Anatomy Source Type: research

Protective effect of human adipose-derived stem cells transplanted to fat grafts against high-power laser therapy mediated fat tissue damage
The objective of this study was to determine the protective effect of human adipose-derived stem cells (hADSCs) against HPLT-mediated fat tissue damage after fat grafts in an in vivo study.MethodsTo determine the viability of fat grafts with transplanted hADSCs, high power laser (HPL) irradiation was performed using a 830 nm gallium–aluminum–arsenide (Ga–Al–As) laser. In the in vivo study, fat grafts with hADSCs/Dulbecco’s modified Eagle’s medium (DMEM) were transplanted and HPL irradiation of each nude mouse was performed per protocol for a period of 13 weeks. Vascular endothelial growth factor (VEGF) and cl...
Source: Journal of the Anatomical Society of India - November 7, 2018 Category: Anatomy Source Type: research

Cytogenetic, epidemiological and clinical profile of children with Down syndrome in Karnataka
ConclusionEfforts should be made to establish early diagnosis and proper screening. Confirmation of clinical diagnosis by Karyotyping is essential to determine the precise diagnosis, calculate recurrence risk and provide basis for genetic counseling. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - November 4, 2018 Category: Anatomy Source Type: research

Calcaneum talar facets, its diagnostic and clinical relevance to fracture
This study is important with the view that fracture involved facet and lead to decrease in calcaneal axial length.DiscussionAn understanding of the complex surgical calcaneal anatomy begins with a 3-D appreciation of the multiple articulations and bony processes. Calcaneal reconstruction is predicted on the restoration of the articular surfaces especially the posterior facet, appropriate reconstruction of the 3 dimentional spatial relationship between three articular facets is of paramount importance. Nature of calcaneal bone (spongy or dense) is important for orthopaedic surgeon in fracture fixation, calcaneum is harder b...
Source: Journal of the Anatomical Society of India - November 3, 2018 Category: Anatomy Source Type: research