Journal of the Egyptian National Cancer Institute This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Laryngeal synovial sarcoma: Report of 2 cases
We report two cases of 27 and 18 year-old men who developed a synovial sarcoma of the larynx. They presented with hoarseness of voice and hemoptysis. Endoscopy detected a mass in the supraglottic region. The biopsy concluded a synovial sarcoma. Immunohistochemistry conveyed diagnostic certainty. They had been treated with total laryngectomy and post-operative radiotherapy. The 2 patients are seen for regular follow-ups in our department and they remained recurrence-free for 10 years and 24 months, respectively.Synovial sarcoma is a very rare tumor of the larynx. A multidisciplinary therapeutic approach is essential f...
Source: Journal of the Egyptian National Cancer Institute - November 25, 2018 Category: Cancer & Oncology Source Type: research

Simultaneous integrated boost by Intensity Modulated Radiotherapy (SIB-IMRT) in patients undergoing breast conserving surgery – A clinical and dosimetric perspective
ConclusionSIB-IMRT is a dosimetrically feasible option in patients undergoing breast conserving surgery and provides good/excellent cosmetic outcome. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 25, 2018 Category: Cancer & Oncology Source Type: research

The prognostic impact of loss of chromosome 7 material detected by fluorescence in situ hybridization (FISH) in myeloid malignancies
ConclusionChromosome 7 analysis has clear impact on the outcome of myeloid malignancies. The prognostic variations between −7 and del(7q) is attributed to multiple factors. Cases with del(7q) have better outcome than cases with −7. FISH provides a powerful tool for detecting and monitoring patients with chromosome 7 abnormalities. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 23, 2018 Category: Cancer & Oncology Source Type: research

Peritoneal carcinomatosis in colorectal cancer: Defining predictive factors for successful cytoreductive surgery and hyperthermic intraperitoneal chemotherapy – A pilot study
ConclusionIn patients with PC-CRC, malignant ascites and PCI > 20 are poor prognostic factors associated with failure to accomplish CRS with consequent poor survival. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 23, 2018 Category: Cancer & Oncology Source Type: research

Combined cytoreductive surgery and hyperthermic intraperitoneal chemotherapy as a treatment for recurrent epithelial ovarian cancer-National Cancer Institute experience
ConclusionsTreatment of recurrent EOC by CRS and HIPEC appears to be promising. However, this line of treatment requires further evaluations and larger studies for better assessment of the potential survival benefits and possible complications. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 23, 2018 Category: Cancer & Oncology Source Type: research

Neuroendocrine tumors of the lung: A five-year retrospective experience of Egyptian NCI (2010–2014)
ConclusionsSCLC subtype, stage IV and initial PS > I are poor prognostic factors for lung NETs associated with shorter survival. This conclusion needs to be confirmed by larger studies. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 23, 2018 Category: Cancer & Oncology Source Type: research

Programmed cell death ligand-1 (PD-L1) expression combined with CD8 tumor infiltrating lymphocytes density in non-small cell lung cancer patients
This study aimed to investigate PD-L1 expression alone and combined with CD8 tumor infiltrating lymphocytes (TILs) density in relation to clinicopathologic parameters and survival in NSCLC patients. Immunohistochemical analysis was used to evaluate PD-L1 expression and CD8 TILs density in 55 NSCLC patients. PD-L1 immunopositivity was detected in 36 (65.5%) of NSCLC cases. PD-L1 expression was significantly related to high tumor grade (p value = 0.038) and low CD8 TILs density (p value = 0.004), whereas no significant relations were detected between PD-L1 expression and tumor stage (p value = 0.121), overall sur...
Source: Journal of the Egyptian National Cancer Institute - October 16, 2018 Category: Cancer & Oncology Source Type: research

Axillary metastasis in clinically node-negative breast cancer
ConclusionsThe results of this study indicate that lymphovascular invasion is associated with axillary metastasis, based on an SLN biopsy. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - October 14, 2018 Category: Cancer & Oncology Source Type: research

Corrigendum to “Osteosarcoma of the jaw: Challenges in the diagnosis and treatment” [J. Egypt. Natl. Cancer Inst. (2018) 7–11]
Publication date: September 2018Source: Journal of the Egyptian National Cancer Institute, Volume 30, Issue 3Author(s): Mohamed Atef ElKordy, Tarek Sherif ElBaradie, Hisham Ismail ElSebai, Sheriff Mohamed Khairalla, Ayman AbdelWahab Amin (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - September 1, 2018 Category: Cancer & Oncology Source Type: research

Ultrasound-guided venous access: “Wire-loaded puncture” technique for paediatric cancer patients
ConclusionThe “wire-loaded puncture” technique is a useful technique, particularly in small veins overcoming the relatively common problem of “resisting wire” after a successful vein entry. The technique has a reasonable learning curve and has shown to be reproducible by different operators, machines and venous access sets. A high resolution ultrasound machine is recommended. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - August 23, 2018 Category: Cancer & Oncology Source Type: research

Inter-observer reproducibility of the Royal College system for reporting thyroid cytology: Experience of the Egyptian National Cancer Institute
ConclusionRCPath reporting system for thyroid FNAC is clinically applicable and can be used for differentiation between benign cases needing observation and follow up on one hand, and malignant cases requiring surgical intervention on the other.The least inter-observer agreement (moderate agreement) was detected for Thy3a, Thy3f and Thy4 categories, necessitating multidisciplinary team meeting before any clinical decision. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - August 23, 2018 Category: Cancer & Oncology Source Type: research

Health related quality of life after urinary diversion. Which technique is better?
ConclusionsWhich type of diversion is the best is still a controversial topic. Egyptian patients may prefer the continent UD to avoid the urostomy appliance and its associated daily-life constraints. Detailed patient counseling and active participation of the patient in selecting the treatment methods are important for better postoperative QoL. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - August 23, 2018 Category: Cancer & Oncology Source Type: research

Osteosarcoma subtypes: Magnetic resonance and quantitative diffusion weighted imaging criteria
ConclusionOsteosarcoma has different pathologic subtypes which correspondingly vary in their imaging criteria and their ADC values. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - July 10, 2018 Category: Cancer & Oncology Source Type: research

Radiotherapeutic factors affecting the incidence of developing hypothyroidism after radiotherapy for head and neck squamous cell cancer
ConclusionsThe V30 may predict risk of developing HT after RT for HNSCC patients. V30 of 42.1%, defined as dose-volumetric threshold of radiation-induced HT, can be useful in treatment planning of HNSCC patients. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - July 10, 2018 Category: Cancer & Oncology Source Type: research

Reinforcing the utility of chick embryo model to in vivo evaluate engraftment of human leukemic stem cells
ConclusionCollectively, our data confirm the engraftment of primary human CD34+ leukemic cells in chick embryo liver, but other experiments are required to verify engraftment in BM and spleen, and to confirm the identity of a putative CD34 orthologous transcript in these two organs. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - July 10, 2018 Category: Cancer & Oncology Source Type: research