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378 records returned

[Haplotype analysis at R778L mutation of ATP7B gene in Korean patients with Wilson disease.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19783878 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Jin HS, Oh B Tags: Korean J Hepatol Source Type: journals

Molecular targeting for treatment of advanced hepatocellular carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatocellular carcinoma (HCC) is a major global health problem, which has a grave morbidity and mortality. Over the past few decades, no effective systemic therapeutic modalities have been established for patients with the unresectable HCC in advanced stage. Sorafenib is a small molecule that blocks cancer cell proliferation by targeting the intracellular signaling pathway at the level of Raf-1 and B-Raf serine-threonine kinases, and exerts an anti-angiogenic effect by targeting the vascular endothelial growth factor receptor-1, 2 and 3, and platelet-derived growth factor receptor-beta tyrosine kinases. Recently, two ...
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Song IH Tags: Korean J Hepatol Source Type: journals

[Haplotype analysis and possible founder effect at the R778L mutation of the ATP7B gene in Korean patients with Wilson's disease.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The arche haplotype of the ATP7B gene in Korean patients with WD may be 5-R778L-4 (D13S315.mutation.D13S316), and it might illustrate a founder effect. PMID: 19783880 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Bae SH, Kim JW, Seo JK Tags: Korean J Hepatol Source Type: journals

Prognostic value of serum osteopontin in hepatocellular carcinoma patients treated with transarterial chemoembolization.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Serum OPN levels were significantly higher in patients with advanced HCC. In addition, HCC patients with low pretreatment serum OPN levels and those for whom serum OPN declined following TACE exhibited better tumor responses and survived for longer. PMID: 19783881 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Kim SH, Chung YH, Yang SH, Kim JA, Jang MK, Kim SE, Lee D, Lee SH, Lee D, Kim KM, Lim YS, Lee HC, Lee YS, Suh DJ Tags: Korean J Hepatol Source Type: journals

[Efficacy of 48-week clevudine therapy for chronic hepatitis B.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: A 48-week course of clevudine therapy was highly effective in patients with CHB. The risk of development of resistance to clevudine was increased in patients with previous exposure to lamivudine and cirrhosis. PMID: 19783882 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Kim MH, Kim KA, Lee JS, Lee HW, Kim HJ, Yun SG, Kim NH, Bae WK, Moon YS Tags: Korean J Hepatol Source Type: journals

Impact of adherence to peginterferon-ribavirin combination therapy in chronic hepatitis C patients on achieving a sustained virologic response.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Adherence to therapy is a key factor in achieving an SVR. Supportive strategies to improve adherence will increase overall SVR rates. PMID: 19783883 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Jeong SW, Kim JD, Woo HY, You CR, Lee SW, Song MJ, Jang JW, Bae SH, Choi JY, Yoon SK Tags: Korean J Hepatol Source Type: journals

[Comparison of the Model for End-stage Liver Disease and hepatic venous pressure gradient for predicting survival in patients with decompensated liver cirrhosis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Both MELD and HVPG are independent prognostic factors of death within 3 and 12 months in patients with decompensated liver cirrhosis, and their accuracies are similar. However, HVPG has a limited role in the prediction of death in decompensated cirrhosis due to its invasiveness and limited use. PMID: 19783884 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Lee SH, Park SH, Kim GW, Lee WJ, Hong WK, Ryu MS, Park KT, Lee MY, Lee CW, Kim JH, Kim YM, Kim SJ, Baik GH, Kim JB, Kim DJ Tags: Korean J Hepatol Source Type: journals

[A case of metastatic hepatocellular carcinoma of the rib, treated by transcatheter arterial chemoembolization.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a rare case of rib metastasis from HCC treated by transcatheter arterial chemoembolization (TACE). A 55-year-old man with liver cirrhosis presented with right lower chest pain. The diagnosis was an HCC with a bone metastasis in the right eighth rib. Intra-arterial injections of doxorubicin mixed with Lipiodol and Gelfoam particles were instituted through the right eighth intercostal artery. Computed tomography and a Tc(99)-labeled scan performed 2 months after the third TACE revealed no viable HCC in the right eighth rib. PMID: 19783885 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Jung YK, Yeon JE, Kim CH, Lee HJ, Lee YS, Yoon EL, Suck JE, Choi JH, Kim JH, Byun KS Tags: Korean J Hepatol Source Type: journals

[Four patients with hepatitis A presenting with fulminant hepatitis and acute renal failure and who underwent liver transplantation.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report four cases of hepatitis A in which patients presented with fulminant hepatitis and acute renal failure and underwent liver transplantation. The following common features were observed in our cases: (1) occurrence in relatively old age (>/=39 years old), (2) association with acute renal failure, (3) presence of hepatomegaly, and (4) microscopic features of submassive hepatic necrosis. PMID: 19783886 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Oh SH, Lee JH, Hwang JW, Kim HY, Lee CH, Gwak GY, Choi MS, Koh KC, Paik SW, Yoo BC Tags: Korean J Hepatol Source Type: journals

[A case of sudden-onset hearing loss in a patient treated with peginterferon alpha-2b and ribavirin for chronic hepatitis C.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a 60-year-old male patient who developed sudden-onset hearing loss during combination therapy with pegylated interferon alpha and ribavirin for chronic hepatitis C. This patient had been diagnosed with chronic hepatitis C (genotype Ib) and early-stage liver cirrhosis 3 years previously, and had been treated with conventional interferon-alpha and ribavirin for 12 months. However, 6 months from the end of the treatment course the patient relapsed and received combination retreatment with pegylated interferon alpha-2b and ribavirin. He developed sudden-onset right-side hearing loss and tinnitus 42 weeks after the st...
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Shin MK, Kim TH, Ju K, Ha CY, Min HJ, Jung WT, Lee OJ Tags: Korean J Hepatol Source Type: journals

[Large liver cell change/dysplasia in hepatitis B virus-related liver cirrhosis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19783888 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Kim H, Park YN Tags: Korean J Hepatol Source Type: journals

[Peliosis hepatis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19783889 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Lee WJ Tags: Korean J Hepatol Source Type: journals

[Clinical outcomes and development of hepatocellular carcinoma after HBsAg seroclearance in chronic hepatitis B patients.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19783890 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Kim JH Tags: Korean J Hepatol Source Type: journals

[Practice guidelines for management of hepatocellular carcinoma 2009.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Hepatocellular carcinoma (HCC) is a major cancer in Korea, typically has a poor prognosis, and constitutes the majority of primary hepatic malignancies. It is the number one cause of death among people in their 50s in Korea. The five-year survival rate of liver cancer is poor; at 18.9%. Efforts to increase the survival rate through early diagnosis of HCC and optimal treatments are keenly needed. Western guideline for the management of HCC were developed, but these guidelines are somewhat unsuitable for Korean patients. Thus, the Korean Liver Cancer Study Group (KLCSG) and the National Cancer Center (NCC), Ko...
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Tags: Korean J Hepatol Source Type: journals

[Corrections: Distribution of hepatitis B virus genotypes in Korea.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19783892 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Cho JH, Yoon KH, Lee KE, Park do S, Lee YJ, Moon HB, Lee KR, Choi CS, Cho EY, Kim HC Tags: Korean J Hepatol Source Type: journals

[Clevudine therapy in patients with chronic hepatitis B.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19581763 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Lee KS Tags: Korean J Hepatol Source Type: journals

[Pathology of nonalcoholic steatohepatitis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nonalcoholic steatohepatitis (NASH), one of the NAFLDs (nonalcoholic fatty liver diseases), is regarded as a hepatic manifestation of metabolic syndrome. NASH can progress to cirrhosis, and possibly to hepatic malignancy. Currently, liver biopsy is the only reliable method of assessing the presence or absence of NASH and the stage of fibrosis. The finding of steatosis with evidence of hepatocyte injury such as inflammation, ballooning, degeneration, and/or fibrosis, is generally essential for making a diagnosis of NASH. However, its diagnostic criteria have not yet been established. The pathologic findings of NASH and ...
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Jeen YM, Jin SY Tags: Korean J Hepatol Source Type: journals

[Change in the serologic markers of hepatitis B after allogenic hematopoietic stem-cell transplantation.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Due to the adoptive immunity that was transferred from anti-HBs-positive donors, a seroconversion of HBsAg could occur in some HBsAg-positive recipients. HBsAg-positive donors had a lesser effect on the HBV serologic markers of recipients. However, a reactivation of HBV can occur following hematopoietic stem-cell transplantation in the cases of recipients or donors with a history of HBV, infection by an accompanying immune suppression. Therefore, prevention should be instigated. PMID: 19581765 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Woo SY, Cho SH, Lee SM, Koh MB, Noh CH, Kim CW, Choi JY, Yang JM, Han JY, Lee YS Tags: Korean J Hepatol Source Type: journals

[Distribution of hepatitis B virus genotypes in Korea.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The prevailing HBV genotype in Korea is C2; the other genotypes occur only rarely. Future studies should include confirmation of the detection of genotypes other than C. PMID: 19581766 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Cho JH, Yoon KH, Lee KE, Park do S, Lee YJ, Moon HB, Lee KR, Choi CS, Cho EY, Kim HC Tags: Korean J Hepatol Source Type: journals

[Analysis of the clinical characteristics and prognostic factors of ruptured hepatocellular carcinoma.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The prognosis in patients with ruptured HCCs was poor with a 30-day mortality of 43.5%. The early deaths after the rupture of HCC were associated with elevated serum bilirubin levels, hepatic encephalopathy, and the massive or diffuse type of tumor morphology. PMID: 19581767 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Kim YI, Ki HS, Kim MH, Cho DK, Cho SB, Joo YE, Kim HS, Choi SK, Rew JS Tags: Korean J Hepatol Source Type: journals

[Clinical features of hepatic tuberculosis in biopsy-proven cases.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In patients with a protracted illness, hepatosplenomegaly and/or abnormal liver function tests, hepatic tuberculosis should be suspected, even in healthy young patients or patients with normal imaging findings. Patients with tuberculous abscess formation tend to respond poorly to antituberculosis therapy, and surgery could be considered in these patients. PMID: 19581768 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Hwang SW, Kim YJ, Cho EJ, Choi JK, Kim SH, Yoon JH, Kim CY, Lee HS Tags: Korean J Hepatol Source Type: journals

[Comparison of lamivudine-induced HBsAg loss rate according to age in children with chronic hepatitis B.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Younger children (age <7 years old) have a higher chance of HBsAg clearance than older children after the treatment of HBeAg-positive chronic hepatitis B with lamivudine. PMID: 19581769 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Kim JM, Choe BH, Chu MA, Cho SM Tags: Korean J Hepatol Source Type: journals

[Long-term clevudine therapy in nucleos(t)ide-naïve and lamivudine-experienced patients with hepatitis B virus-related chronic liver diseases.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Clevudine is one of the recommended first-line medicines for the treatment of chronic hepatitis B, but it is not free from resistance, particularly in patients with a history of previous lamivudine treatment, but also in naive patients. Clevudine should be avoided in previously lamivudine-exposed patients. In addition, reelevation of serum AST and CPK levels is not a rare occurrence, and close observation and follow-up tests are essential. PMID: 19581770 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Lee HJ, Eun JR, Lee CH, Hwang JS, Suh JI, Kim BS, Jang BK Tags: Korean J Hepatol Source Type: journals

[A case of hypervascular hyperplastic nodules mimicking hepatocellular carcinoma in alcoholic liver cirrhosis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report herein a case of benign HHN mimicking hepatocellular carcinoma in a 32-year-old male alcoholic liver cirrhosis patient without viral hepatitis infection. PMID: 19581771 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Park JE, Kim BS, Lee CH, Choi JH, Park YC, Park KK Tags: Korean J Hepatol Source Type: journals

[A case of liver metastasis of gastric hepatoid adenocarcinoma.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report herein a case of hepatoid adenocarcinoma of the stomach with liver metastasis. Gastric carcinoma generally presents as adenocarcinoma and rarely shows a hepatoid pattern, which can produce alpha-fetoprotein (AFP). The stomach is one of the common sites at which hepatoid adenocarcinoma has been detected. A 75-year-old female patient was admitted to the hospital with a symptom of epigastric discomfort. Gastrofibroscopy revealed a large tumor occupying the greater curvature of the stomach body. The level of serum AFP was markedly increased. Abdominal computed tomography revealed multiple liver masses. Biopsy samples...
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Jeong EH, Kim DH, Ma SH, Chung EJ, Bae SS, Park AY, Chu HJ Tags: Korean J Hepatol Source Type: journals

Development of ocular myasthenia during pegylated interferon and ribavirin treatment for chronic hepatitis C.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 63-year-old male experienced sudden diplopia after 9 weeks of administration of pegylated interferon (IFN) alpha-2b and ribavirin for chronic hepatitis C (CHC). Ophthalmologic examinations showed ptosis on the right upper lid and restricted right eye movement without any other neurological signs. A brain imaging study and repetitive nerve stimulation test indicated no abnormality. The acetylcholine receptor antibody titer and response to acetylcholinesterase inhibitors were negative, and the results of thyroid function tests were normal. The patient's ophthalmological symptoms improved rapidly 3 weeks after discontin...
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Kang HM, Park MJ, Hwang JM, Kim JW, Jeong SH Tags: Korean J Hepatol Source Type: journals

[Primary angiosarcoma of the liver.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19581774 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Seok JY, Kim YB Tags: Korean J Hepatol Source Type: journals

[Epithelioid hemangioendothelioma.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19581775 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Lee WJ Tags: Korean J Hepatol Source Type: journals

Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19581776 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - May 31, 2009 Category: Gastroenterology Authors: Heo J Tags: Korean J Hepatol Source Type: journals

[Inhibition of hepatitis B virus replication by RNA interference.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19346780 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Park YG Tags: Korean J Hepatol Source Type: journals

[Genetic epidemiological study on single nucleotide polymorphisms associated with hepatocellular carcinoma in patients with chronic HBV infection.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatocellular carcinoma (HCC) is associated with hepatitis B virus (HBV) as an etiologic agent in 80% of cases, and is the major cause of death among HBV carriers. Family history of HCC is a known risk factor for the development of HCC among chronically HBV infected patients; therefore, genetic factors are likely to modify the risk of HCC. However, the genetic factors that determine progression to HCC remain mostly to be recovered. It is estimated that there are millions of single nucleotide polymorphisms (SNPs) within human genome and they are likely to explain much of the genetic diversity of individuals. In this re...
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Kim YJ, Lee HS Tags: Korean J Hepatol Source Type: journals

[Inhibition of in vitro hepatitis B virus replication by lentivirus-mediated short-hairpin RNA against HBx.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Lentivirus-mediated delivery of shRNA against HBx can effectively suppress the replication of HBV and reduce HBV cccDNA in cell culture systems. PMID: 19346782 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Kim JW, Lee SH, Park YS, Jeong SH, Kim N, Lee DH Tags: Korean J Hepatol Source Type: journals

[Analysis of the cost-effectiveness of antiviral therapies in chronic hepatitis B patients in Korea.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Antiviral treatment of CHB with LMV or ADV for up to 5 years using the alternative antiviral agent as rescue medication appears to be a cost-effective strategy for both HBeAg-positive and HBeAg-negative CHB patients in Korea. Economic evaluation of antiviral therapies should be studied further and updated, particularly for newer agents. PMID: 19346783 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Kim BK, Kwon SY, Lee CH, Choe WH, Choi HM, Koo HW Tags: Korean J Hepatol Source Type: journals

[The usefulness of transient elastography to diagnose cirrhosis in patients with alcoholic liver disease.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Transient elastography is a useful method for diagnosing cirrhosis in patients with alcoholic liver disease. PMID: 19346784 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Kim SG, Kim YS, Jung SW, Kim HK, Jang JY, Moon JH, Kim HS, Lee JS, Lee MS, Shim CS, Kim BS Tags: Korean J Hepatol Source Type: journals

[Virologic response to adefovir dipivoxil monotherapy is not durable in HBeAg-positive, lamivudine-resistant chronic hepatitis B patients.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Our data suggest that the adefovir-monotherapy-induced virologic response is not durable in most patients with LAMV-R HBeAg-positive CHB, especially in those with a high pretreatment HBV DNA level. PMID: 19346785 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Jung HW, Choi MS, Kim KH, Park SH, Yeon KK, Lee JH, Koh KC, Paik SW, Yoo BC Tags: Korean J Hepatol Source Type: journals

[The value of serum retinol-binding protein 4 levels for determining disease severity in patients with chronic liver disease.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The results of our study suggest that RBP4 is a serologic marker for disease severity in patients with CLD. It could also be useful as an early marker of CLD and of the relative success of antiviral therapy. PMID: 19346786 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Kwon JH, Park ST, Kim GD, You CR, Kim JD, Woo HY, Jang JW, Kim CW, Bae SH, Choi JY, Yoon SK Tags: Korean J Hepatol Source Type: journals

[Durability of a sustained virologic response in combination therapy with interferon/peginterferon and ribavirin for chronic hepatitis C.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Reappearance of HCV RNA after earlier achievement of an SVR might appear more frequently than previously reported. Close follow-up of these patients is recommended and the implication of temporary viremia should be determined in the future. PMID: 19346787 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Kim CH, Park BD, Lee JW, Kim YS, Jeong S, Lee DH, Kim HG, Shin YW, Kwon KS, Lee JI Tags: Korean J Hepatol Source Type: journals

[A case of hepatocellular carcinoma invading the gallbladder misdiagnosed as a primary gallbladder carcinoma.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report here a case of HCC that directly invaded the gallbladder, and that resembled gallbladder carcinoma invading the liver. PMID: 19346788 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Ryu HS, Hwang ET, Choi CS, Kim TH, Kim HC, Yun KJ, Park DE Tags: Korean J Hepatol Source Type: journals

[A case of rhabdomyolysis during hospitalization for acute hepatitis A.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of acute hepatitis A complicated by rhabdomyolysis during hospitalization. PMID: 19346789 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Ann SH, An GH, Lee SY, Oak JH, Moon HI, Moon SK, Han NI, Lee YS Tags: Korean J Hepatol Source Type: journals

[A case of advanced hepatocellular carcinoma with portal vein tumor invasion controlled by percutaneous ethanol injection therapy.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report here a case of advanced HCC with portal vein tumor thrombosis that was effectively treated with percutaneous ethanol injection (PEI), having previously enabled subsequent successive transarterial chemoembolization (TACE). A 60-year-old male patient was diagnosed with a huge HCC, based on computed tomography and angiographic findings. Despite two sessions of TACE, the tumor invaded the right portal vein. PEI was performed on the malignant portal vein thrombosis, and three sessions thereof reduced the extent of tumor thrombi in the portal vein. Successive TACEs were performed to treat the HCC in the hepatic parench...
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Yoon I, Yim HJ, Kim JN, Park SM, Kim JH, Lee SH, Chung HH, Lee HS, Lee SW, Choi JH Tags: Korean J Hepatol Source Type: journals

[Well differentiated hepatocellular carcinoma: ddmPathological diagnosis of needle biopsied liver tissue.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19346791 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Seok JY, Park YN Tags: Korean J Hepatol Source Type: journals

[Angiosarcoma.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19346792 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Lee WJ Tags: Korean J Hepatol Source Type: journals

Treatment recommendations for chronic hepatitis B: an evaluation of current guidelines based on a natural history study in the United States.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19346793 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - March 1, 2009 Category: Gastroenterology Authors: Park NH Tags: Korean J Hepatol Source Type: journals

[Treatment of chronic hepatitis C: efficacy of initial treatment of peginterferon alpha-2a versus peginterferon alpha-2b plus ribavirin in naive chronic hepatitis C patients]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19119239 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol)
Source: Korean J Hepatol - December 1, 2008 Category: Gastroenterology Authors: Lee YJ Tags: Korean J Hepatol Source Type: journals

[Hepatitis B virus genetic diversity and mutant]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatitis B virus (HBV) is a partially double stranded DNA virus with genetic diversity represented by eight genotypes (A to H). Natural course and response to treatment could be affected by HBV genotypes. HBV shows high rates of turn over in the absence of proof-reading ability. As a result, large amounts of quasispecies are produced naturally or antiviral-associated. HBV consists of four open reading frames, namely preS/S gene, precore/core gene, polymerase gene, and X gene. Mutations on preS gene can result in undetectable HBsAg even in case that HBV is replicating. Surface gene mutation leads to decreased binding a...
Source: Korean J Hepatol - December 1, 2008 Category: Gastroenterology Authors: Yim HJ Tags: Korean J Hepatol Source Type: journals

[Clinical outcomes and predictive factors of spontaneous survival in patients with fulminant hepatitis A]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: FHF due to hepatitis A has increased in recent years, and in our cohort the HEP grade was closely associated with spontaneous survival. PMID: 19119242 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol)
Source: Korean J Hepatol - December 1, 2008 Category: Gastroenterology Authors: Kim JM, Lee YS, Lee JH, Kim W, Lim KS Tags: Korean J Hepatol Source Type: journals

[Clinical characteristics of 159 cases of acute toxic hepatitis]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The main cause of acute toxic hepatitis in the current study was the use of herbal medicines. The severity of liver injury at the time of admission was a major factor significantly associated with the hospitalization and recovery periods. PMID: 19119243 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol)
Source: Korean J Hepatol - December 1, 2008 Category: Gastroenterology Authors: Kang SH, Kim JI, Jeong KH, Ko KH, Ko PG, Hwang SW, Kim EM, Kim SH, Lee HY, Lee BS Tags: Korean J Hepatol Source Type: journals

[Efficacy of initial treatment with peginterferon alpha-2a versus peginterferon alpha-2b in combination with ribavirin in naive chronic hepatitis C patients living in Daejeon and Chungcheong Province in Korea: a comparative study]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: We found no significant differences in therapeutic efficacies and adverse effects between the alpha-2a and -2b types of peginterferon as the initial treatment regimen in naive chronic hepatitis C patients. PMID: 19119244 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol)
Source: Korean J Hepatol - December 1, 2008 Category: Gastroenterology Authors: Kim JI, Kim SH, Lee BS, Lee HY, Lee TH, Kang YW, Lee HIe, Kim AN, Nam SW, Park BC, Chae HB, Kim SB, Song IH, Park JY, Kim HS Tags: Korean J Hepatol Source Type: journals

[The efficacy of adefovir dipivoxil monotherapy and the incidence of genotypic resistance to adefovir dipivoxil in patients with lamivudine-resistant chronic hepatitis B infection]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Although ADV monotherapy is effective, it leads to a high rate of mutations of HBV DNA reverse transcriptase gene in patients with chronic HBV infections who have LMV-resistant HBV mutants. PMID: 19119245 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol)
Source: Korean J Hepatol - December 1, 2008 Category: Gastroenterology Authors: Moon JH, Cho M, Yoon KT, Bae JH, Heo J, Kim GH, Kang DH, Song GA Tags: Korean J Hepatol Source Type: journals

[A case report of treatment with pegylated interferon alpha for lamivudine-resistant chronic hepatitis B virus infection]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The wide use of lamivudine in chronic hepatitis B has produced a monotonic increase in patients with lamivudine resistance. Therefore, treating lamivudine resistance in chronic hepatitis B is a major concern in clinical practice for the treatment of hepatitis B virus (HBV). There is conflicting evidence on the outcome of pegylated interferon alpha (PEG-IFN alpha) therapy against lamivudine-resistant HBV, which is due to mutations in the YMDD motif. We experienced a patient with chronic hepatitis B who was successfully treated with PEG-IFN alpha-2a after the development of virologic and biochemical breakthrough during l...
Source: Korean J Hepatol - December 1, 2008 Category: Gastroenterology Authors: Hur WH, Woo HY, Jeong SW, You CR, Bae SH, Choi JY, Yoon SK Tags: Korean J Hepatol Source Type: journals