Two-dimensional perfusion angiography permits direct visualization of redistribution of flow in hepatocellular carcinoma during b-TACE
ConclusionThe measurements identify predictively the flow redistribution in the hepatic arteries during b-TACE, supporting a proper positioning of the balloon microcatheter. (Source: La Radiologia Medica)
Source: La Radiologia Medica - April 18, 2024 Category: Radiology Source Type: research
Ultrasound-based radiomics for early predicting response to neoadjuvant chemotherapy in patients with breast cancer: a systematic review with meta-analysis
ConclusionUS-based radiomics may be a potentially crucial adjuvant method for evaluating the response of breast cancer to NAC. Due to limited data available and low quality of eligible studies, more multicenter prospective studies with rigorous methods are required to confirm our findings. (Source: La Radiologia Medica)
Source: La Radiologia Medica - April 17, 2024 Category: Radiology Source Type: research
Assessing osteoporosis in postmenopausal women: preliminary results using a novel lumbar spine phantom-based MRI scoring method
ConclusionA novel real-time lumber spine MRI phantom was developed, based upon which newly definedF-score andW-score were able to detect osteoporosis and demonstrated an improved ability over DXA-aBMD in differentiating patients with vertebral fractures. (Source: La Radiologia Medica)
Source: La Radiologia Medica - April 16, 2024 Category: Radiology Source Type: research
Assessing the malignancy of suspicious breast microcalcifications: the role of contrast enhanced mammography
ConclusionsThe absence of enhancement can be used as an indicative parameter for the absence of disease in cases of low-suspicious microcalcifications, but not in intermediate-high suspicious ones for which biopsy remains mandatory and can be used to distinguish indolent lesions from more aggressive neoplasms, with consequent reduction of overdiagnosis and overtreatment. (Source: La Radiologia Medica)
Source: La Radiologia Medica - April 12, 2024 Category: Radiology Source Type: research
Anatomical assessment of local recurrence site in breast cancer patients after breast reconstruction and post-mastectomy radiotherapy: implications for radiation volumes and techniques
ConclusionsThe onset of local –regional relapses occurred mainly above the expander/prosthesis, underlying the importance of inclusion of the subcutaneous tissues within the target volume. In order to refine new contouring recommendations for PMRT and breast reconstruction, future prospective studies are needed. (Source: La Radiologia Medica)
Source: La Radiologia Medica - April 11, 2024 Category: Radiology Source Type: research
Quantitative ultrasound (QUS) in the evaluation of liver steatosis: data reliability in different respiratory phases and body positions
In conclusion, this technology also allows to monitor uncompliant patients, as it grants high relia bility and reproducibility in different body position and respiratory phases. (Source: La Radiologia Medica)
Source: La Radiologia Medica - April 1, 2024 Category: Radiology Source Type: research
Diagnostic accuracy of qualitative and quantitative magnetic resonance imaging-guided contrast-enhanced ultrasound (MRI-guided CEUS) for the detection of prostate cancer: a prospective and multicenter study
ConclusionWe developed a reliable method of MRI-guided CEUS that demonstrated enhanced performance compared to MRI. The qualitative and quantitative CEUS characteristics will contribute to improved diagnosis of PCa. (Source: La Radiologia Medica)
Source: La Radiologia Medica - April 1, 2024 Category: Radiology Source Type: research
Multi-omics staging of locally advanced rectal cancer predicts treatment response: a pilot study
AbstractTreatment response assessment of rectal cancer patients is a critical component of personalized cancer care and it allows to identify suitable candidates for organ-preserving strategies. This pilot study employed a novel multi-omics approach combining MRI-based radiomic features and untargeted metabolomics to infer treatment response at staging. The metabolic signature highlighted how tumor cell viability is predictively down-regulated, while the response to oxidative stress was up-regulated in responder patients, showing significantly reduced oxoproline values at baseline compared to non-responder patients (p-valu...
Source: La Radiologia Medica - March 27, 2024 Category: Radiology Source Type: research
MRI-based radiomics for prediction of extraprostatic extension of prostate cancer: a systematic review and meta-analysis
ConclusionsMRI radiomics demonstrated moderate sensitivity and specificity, offering similar diagnostic performance with previous risk stratifications and models that primarily based on radiologists ’ subjective experience. However, all studies included were retrospective, thus the performance of radiomics needs to validate in prospective, multicenter studies. (Source: La Radiologia Medica)
Source: La Radiologia Medica - March 23, 2024 Category: Radiology Source Type: research
Efficacy of radiofrequency in lumbar facet joint pain: a systematic review and meta-analysis of placebo-controlled randomized controlled trials
ConclusionsRF demonstrated significant improvement in pain and functionality, but the benefits in terms of QoL and GPE are inconclusive. Future clinical trials should investigate the long-term effects of RF, its impact on quality of life, and define appropriate criteria for patient selection. (Source: La Radiologia Medica)
Source: La Radiologia Medica - March 21, 2024 Category: Radiology Source Type: research
The features associated with mammography-occult MRI-detected newly diagnosed breast cancer analysed by comparing machine learning models with a logistic regression model
ConclusionMammography-occult MRI-detected breast cancers have features that should be considered when performing breast MRI to improve the detection rate for breast cancer and aid in clinician management. (Source: La Radiologia Medica)
Source: La Radiologia Medica - March 21, 2024 Category: Radiology Source Type: research
The risk-based breast screening (RIBBS) study protocol: a personalized screening model for young women
This study is registered on Clinicaltrials.gov (NCT05675085). (Source: La Radiologia Medica)
Source: La Radiologia Medica - March 21, 2024 Category: Radiology Source Type: research
Radiomics-enhanced early regression index for predicting treatment response in rectal cancer: a multi-institutional 0.35 T MRI-guided radiotherapy study
ConclusionThe integration of the radiomic analysis with ERITCP improves the pCR prediction in LARC patients, offering more precise predictive models to further personalise 0.35 T MRIgRT treatments of LARC patients. (Source: La Radiologia Medica)
Source: La Radiologia Medica - March 21, 2024 Category: Radiology Source Type: research
CT prognostic signs of postoperative complications in emergency surgery for acute obstructive colonic cancer
ConclusionPostoperative complications in emergency surgery of AOCC were not related to the age, sex and tumor ’s location. Preoperative PCR values (≥ 2.17) predict the development of postoperative complications. CT resulted a valid diagnostic tool to identify patients at higher risk of complications: a CD/L1-VD ratios with cut-off values of 1.43 (transverse) and 1.31 (descending) predicted major com plications (grade ≥ III-V) and a cecum distension ≥ 9 cm represented the critical diameter beyond which perforation occurred in > 84% of patients. (Source: La Radiologia Medica)
Source: La Radiologia Medica - March 21, 2024 Category: Radiology Source Type: research
Development and validation of nomograms to evaluate the survival outcome of HCC patients undergoing selective postoperative adjuvant TACE
ConclusionThe nomograms were developed and validated based on large-scale clinical data and can serve as online decision-making tools to predict survival benefits from PA-TACE in different subgroups of patients. (Source: La Radiologia Medica)
Source: La Radiologia Medica - March 21, 2024 Category: Radiology Source Type: research
