The new WHO 2022 and ICC proposals for the classification of myelodysplastic neoplasms. Validation based on the Düsseldorf MDS Registry and proposals for a merged classification
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02157-2The new WHO 2022 and ICC proposals for the classification of myelodysplastic neoplasms. Validation based on the Düsseldorf MDS Registry and proposals for a merged classification (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: K. Nachtkamp C. Strupp M. Vukelja A. Kasprzak D. Haase C. Ganster B. Hildebrandt B. Betz A. Giagounidis C. Aul S. Blum W. K. Hofmann M. Pfeilst öcker P. Valent M. L übbert M. Seidl M. Rudelius R. Stauder O. Krieger K. S. G ötze J. Bobak A. K ündgen F. Source Type: research

Clinical evaluation of complete remission (CR) with partial hematologic recovery (CRh) in acute myeloid leukemia: a report of 7235 patients from seven cohorts
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02143-8Clinical evaluation of complete remission (CR) with partial hematologic recovery (CRh) in acute myeloid leukemia: a report of 7235 patients from seven cohorts (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: Jacob S. Appelbaum Andrew H. Wei Sumithra J. Mandrekar Ing S. Tiong Chong Chyn Chua Tse-Chieh Teh Chun Yew Fong Stephen B. Ting Daniela Weber Axel Benner Hannah Hill Maral Saadati Jun Yin Richard M. Stone Guillermo Garcia-Manero Harry P. Erba Geoffrey L. Source Type: research

Concerns regarding myelofibrosis-type megakaryocyte dysplasia
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02160-7Concerns regarding myelofibrosis-type megakaryocyte dysplasia (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: Yanan Cai Yuebo Wang Jing Yang Zunmin Zhu Source Type: research

Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02147-4Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: Harpreet K. Mandhair Ramin Radpour Mira Westerhuis Yara Banz Magali Humbert Miroslav Arambasic J örn Dengjel Andrew Davies Mario P. Tschan Urban Novak Source Type: research

Peri-transplant flow-MRD assessment of cells with leukemic stem cells (LSC) associated phenotype in AML patients undergoing allogeneic stem cell transplantation in CR
Leukemia, Published online: 23 January 2024; doi:10.1038/s41375-024-02148-3Peri-transplant flow-MRD assessment of cells with leukemic stem cells (LSC) associated phenotype in AML patients undergoing allogeneic stem cell transplantation in CR (Source: Leukemia)
Source: Leukemia - January 23, 2024 Category: Hematology Authors: Evgeny Klyuchnikov Anita Badbaran Radwan Massoud Petra Freiberger Christine Wolschke Francis Ayuk Boris Fehse Ulrike Bacher Nicolaus Kr öger Source Type: research

Inherent genome instability underlies trisomy 21-associated myeloid malignancies
Leukemia, Published online: 20 January 2024; doi:10.1038/s41375-024-02151-8Inherent genome instability underlies trisomy 21-associated myeloid malignancies (Source: Leukemia)
Source: Leukemia - January 20, 2024 Category: Hematology Authors: Chun-Chin Chen Rebecca E. Silberman Duanduan Ma Jennifer A. Perry Delan Khalid Yana Pikman Angelika Amon Michael T. Hemann R. Grant Rowe Source Type: research

Real-world analysis of teclistamab in 123 RRMM patients from Germany
Leukemia, Published online: 20 January 2024; doi:10.1038/s41375-024-02154-5Real-world analysis of teclistamab in 123 RRMM patients from Germany (Source: Leukemia)
Source: Leukemia - January 20, 2024 Category: Hematology Authors: C. Riedhammer F. Bassermann B. Besemer M. Bewarder F. Brunner A. Carpinteiro H. Einsele J. Faltin J. Frenking D. Gezer S. Goldman-Mazur M. H änel M. Hoegner K. M. Kortuem J. Kr önke M. Kull T. Leitner C. Mann R. Mecklenbrauck M. Merz A. Morgner A. Nogai Source Type: research

Ontogeny shapes the ability of ETV6::RUNX1 to enhance hematopoietic stem cell self-renewal and disrupt early lymphopoiesis
Leukemia, Published online: 19 January 2024; doi:10.1038/s41375-024-02149-2Ontogeny shapes the ability of ETV6::RUNX1 to enhance hematopoietic stem cell self-renewal and disrupt early lymphopoiesis (Source: Leukemia)
Source: Leukemia - January 19, 2024 Category: Hematology Authors: Mohamed Eldeeb Anna Konturek-Ciesla Qinyu Zhang Shabnam Kharazi Johanna Tingvall-Gustafsson Jonas Ungerb äck Mikael Sigvardsson David Bryder Source Type: research

Recurrent DDX41 mutation in very late relapse after allogeneic stem cell transplantation
Leukemia, Published online: 18 January 2024; doi:10.1038/s41375-024-02152-7Recurrent DDX41 mutation in very late relapse after allogeneic stem cell transplantation (Source: Leukemia)
Source: Leukemia - January 18, 2024 Category: Hematology Authors: Yasuhiro Kambara Daichi Sadato Takashi Toya Akira Honda Seiko Kato Chizuko Hirama Kyoko Haraguchi Hiroaki Shimizu Yuho Najima Takeshi Kobayashi Yoshiki Okuyama Hironori Harada Satoshi Takahashi Mineo Kurokawa Yuka Harada Noriko Doki Source Type: research

Lymphoma-associated hemophagocytic lymphohistiocytosis (LA-HLH): a scoping review unveils clinical and diagnostic patterns of a lymphoma subgroup with poor prognosis
Leukemia, Published online: 18 January 2024; doi:10.1038/s41375-024-02135-8Lymphoma-associated hemophagocytic lymphohistiocytosis (LA-HLH): a scoping review unveils clinical and diagnostic patterns of a lymphoma subgroup with poor prognosis (Source: Leukemia)
Source: Leukemia - January 18, 2024 Category: Hematology Authors: Johanna Knauft Thomas Schenk Thomas Ernst Ulf Schnetzke Andreas Hochhaus Paul La Ros ée Sebastian Birndt Source Type: research

OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia
Leukemia, Published online: 17 January 2024; doi:10.1038/s41375-024-02146-5OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia (Source: Leukemia)
Source: Leukemia - January 17, 2024 Category: Hematology Authors: HyunJun Kang Dinh Hoa Hoang Melissa Valerio Khyatiben Pathak Lianjun Zhang Ralf Buettner Fang Chen Katrina Estrella William Graff Zhuo Li Jun Xie David Horne Ya-Huei Kuo Bin Zhang Patrick Pirrotte Le Xuan Truong Nguyen Guido Marcucci Source Type: research

Prognostic impact of CEBPA mutational subgroups in adult AML
Leukemia, Published online: 16 January 2024; doi:10.1038/s41375-024-02140-xPrognostic impact of CEBPA mutational subgroups in adult AML (Source: Leukemia)
Source: Leukemia - January 16, 2024 Category: Hematology Authors: Julia-Annabell Georgi Sebastian Stasik Michael Kramer Manja Meggendorfer Christoph R öllig Torsten Haferlach Peter Valk David Linch Tobias Herold Nicolas Duployez Franziska Taube Jan Moritz Middeke Uwe Platzbecker Hubert Serve Claudia D. Baldus Carsten M Source Type: research

Clonal medicine targeting DNA damage response eradicates leukemia
Leukemia, Published online: 16 January 2024; doi:10.1038/s41375-024-02138-5Clonal medicine targeting DNA damage response eradicates leukemia (Source: Leukemia)
Source: Leukemia - January 16, 2024 Category: Hematology Authors: Monika M. Toma Adam Karami Margaret Nieborowska-Skorska Kumaraswamy Naidu Chirtala Monika Pepek Emir Hadzijusufovic Tomasz Stoklosa Peter Valent Tomasz Skorski Source Type: research

MDS-PB13 Score - Blood based detection of aberrancies by flow cytometry in patients with suspected and confirmed Myelodysplastic Neoplasms
Leukemia, Published online: 16 January 2024; doi:10.1038/s41375-024-02141-wMDS-PB13 Score - Blood based detection of aberrancies by flow cytometry in patients with suspected and confirmed Myelodysplastic Neoplasms (Source: Leukemia)
Source: Leukemia - January 16, 2024 Category: Hematology Authors: Uta Oelschlaegel Susann Winter Katja Sockel Katharina Epp Jonas Schadt Maximilian A. R öhnert Thomas Kr üger Leo Ruhnke Martin Bornh äuser Uwe Platzbecker Frank Kroschinsky Malte von Bonin Source Type: research

Inflammatory recruitment of healthy hematopoietic stem and progenitor cells in the acute myeloid leukemia niche
Leukemia, Published online: 16 January 2024; doi:10.1038/s41375-024-02136-7Inflammatory recruitment of healthy hematopoietic stem and progenitor cells in the acute myeloid leukemia niche (Source: Leukemia)
Source: Leukemia - January 16, 2024 Category: Hematology Authors: Ding-Wen Chen Jian-Meng Fan Julie M. Schrey Dana V. Mitchell Seul K. Jung Stephanie N. Hurwitz Empar B. Perez Mauro J. Muraro Martin Carroll Deanne M. Taylor Peter Kurre Source Type: research