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AspiringDocs.org Video ContestEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Reveal the Doctor in You: What Motivates You to Increase Diversity in Medicine? Our world is becoming increasingly diverse, requiring a diverse physician workforce that can identify with the cultural needs of different patients. As an AspiringDoc--what motivates you to increase diversity in medicine? Submit a 2-minute video telling us your story and you could be one of 10 winners to receive $600 toward medical school preparation and application costs. Just think--your video camera could be the first tool in your doctor's bag. To enter: Record a video, no longer than 2 minutes, that answers the question: What motivates yo...
Source: ScanGrants feed - November 9, 2009 Category: Research Authors: AspiringDocs.org Video Contest Source Type: funding

You Majored in What? And You're Going to Med School?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the world of linear career thinking we often take comfort in what we know to be "true." Pre-med students should major in biology, of course. Pre-law students should major in political science or economics. The problem is that the truth isn't nearly as obvious as it might seem. Or even true.While waiting to do a television interview about my book yesterday, I had an interesting conversation with a dentist who was waiting to do an interview about good and bad Halloween candy. (By the way did you know that pretzels and raisins can be worse for your teeth than candy? But I digress...) When he learned that my book was about ...
Source: Psychology Today Work Center - October 30, 2009 Category: Psychiatry & Psychology Authors: Katharine Brooks, Ed.D. Tags: Work Admissions art classes business courses chaos theory College majors College student cosmetic dentistry dental school faculty members halloween candy law school law students linear response lsat MCAT med students medi Source Type: consumer

99 Best Blogs for Pre-Med StudentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
These blogs will give pre-med students the upper hand on medical knowledge, current events and health care answers. Recognized as a vital learning tool for pre-med students and patients alike, medical blogs are a must-read for education and entertainment. Whether you are applying to medical school, already enrolled or just have an affinity for medicine, these blogs will further your interest, make you laugh often and maybe even prompt you to write a blog of your own! Student Blogs All pre-med students have been in your shoes. They had to take the MCAT, apply to medical schools and make the grades to graduate. Reading helpf...
Source: LPN to RN Blog - October 19, 2009 Category: Nursing Authors: Site Administrator Tags: Uncategorized Source Type: info

Do MCAT verbal and MCAT writing scores correlate with performance on a third-year OSCE?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19816821 [PubMed - in process] (Source: Famly Medicine)
Source: Famly Medicine - September 30, 2009 Category: Primary Care Authors: Stephens MB, Reamy BV Tags: Fam Med Source Type: journals

Removal of either N-glycan site from the envelope receptor binding domain of Moloney and Friend but not AKV mouse ecotropic gammaretroviruses alters receptor usage.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Three N-linked glycosylation sites were removed from the envelope glycoproteins of Friend, Moloney, and AKV mouse ecotropic gammaretroviruses: gs1 and gs2, in the receptor binding domain; and gs8, in a region implicated in post-binding cell fusion. Mutants were tested for their ability to infect rodent cells expressing 4 CAT-1 receptor variants. Three mutants (Mo-gs1, Mo-gs2, and Fr-gs1) infect NIH 3T3 and rat XC cells, but are severely restricted in Mus dunni cells and Lec8, a Chinese hamster cell line susceptible to ecotropic virus. This restriction is reproduced in ferret cells expressing M. dunni dCAT-1, but not in...
Source: Virology - July 5, 2009 Category: Virology Authors: Knoper RC, Ferrarone J, Yan Y, Lafont BA, Kozak CA Tags: Virology Source Type: journals

The influence of regional basic science campuses on medical students' choice of specialty and practice location: a historical cohort studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Attending a regional campus for preclinical training appears to increase the likelihood of practicing primary care medicine in local communities. (Source: BMC Medical Education)
Source: BMC Medical Education - June 6, 2009 Category: Universities & Medical Training Authors: James BrokawChristina MandzukMichael WadeDennis DealMary JohnsonGary WhiteJeffrey WilsonTerrell Zollinger Source Type: journals

Medical school curricula: do curricular approaches affect competence in medicine?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Various formal curricular approaches have little differential effect on students' performance on the USMLE. PMID: 19492189 [PubMed - in process] (Source: Famly Medicine)
Source: Famly Medicine - May 31, 2009 Category: Primary Care Authors: Hecker K, Violato C Tags: Fam Med Source Type: journals

Supports and obstacles in the medical school application process for American Indians and Alaska Natives.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: A conceptual framework that considers both supports and obstacles in the medical school application process will improve our understanding of the needs of AI/AN applicants. PMID: 19395832 [PubMed - in process] (Source: Journal of Health Care for the Poor and Underserved)
Source: Journal of Health Care for the Poor and Underserved - April 30, 2009 Category: Global & Universal Authors: Patterson DG, Baldwin LM, Olsen PM Tags: J Health Care Poor Underserved Source Type: journals

UCLA ranks 11th among U.S. medical schools in annual surveyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The David Geffen School of Medicine at UCLA ranks 11th among the nation's research-based medical schools and 10th among primary care medical school programs, according to U.S. News & World Report's annual survey of the best graduate schools in the United States. The 2010 edition of "America's Best Graduate Schools" — slated to hit newsstands April 28 and currently available online at www.usnews.com/grad — is the most comprehensive listing of its kind, with more than 1,500 graduate school programs nationwide. In addition to its overall ranking, the Geffen School of Medicine also received high marks in ...
Source: UCLA Newsroom: Health Sciences - April 24, 2009 Category: Universities & Medical Training Source Type: organizations

Get Into Medical SchoolEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
If you have applied, or are planning to apply, to medical school, have you ever wondered how the schools select which students to accept? Many students meet the basic requirements of grades and MCAT scores, but you must have more than that to ensure your successful acceptance into medical school. (Source: About.com Health Careers)
Source: About.com Health Careers - March 7, 2009 Category: Universities & Medical Training Authors: healthcareers.guide at about.com Tags: careers Source Type: consumer

McatEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MCAT - What is MCAT - Definition of MCAT (Source: About.com Health Careers)
Source: About.com Health Careers - March 7, 2009 Category: Universities & Medical Training Tags: careers Source Type: info

Calif. court denies extra MCAT time for students with learning disabilitiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recent amendments to the Americans with Disabilities Act may help address some concerns at issue in the case. (Source: American Medical News)
Source: American Medical News - March 2, 2009 Category: American Health Source Type: news

A Box-Cox normal model for response times.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The log-transform has been a convenient choice in response time modelling on test items. However, motivated by a dataset of the Medical College Admission Test where the lognormal model violated the normality assumption, the possibilities of the broader class of Box-Cox transformations for response time modelling are investigated. After an introduction and an outline of a broader framework for analysing responses and response times simultaneously, the performance of a Box-Cox normal model for describing response times is investigated using simulation studies and a real data example. A transformation-invariant implementa...
Source: The British Journal of Mathematical and Statistical Psychology - January 30, 2009 Category: Statistics Authors: Entink RH, van der Linden WJ, Fox JP Tags: Br J Math Stat Psychol Source Type: journals

The mitochondrial theory of aging: Insight from transgenic and knockout mouse models.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A substantial body of evidence has accumulated over the past 35 years in support of a role for oxidative damage to the mitochondrial respiratory chain and mitochondrial DNA in the determination of mammalian lifespan. The goal of this review is to provide a concise summary of recent studies using transgenic and knockout mouse models with altered expression of mitochondrial antioxidant enzymes (MnSOD (Sod2Tg and Sod2(+/-)), thioredoxin 2 (Trx2(+/-)), mitochondrial targeted catalase (mCAT) and mutant mice models that have been genetically manipulated to increase mitochondrial deletions or mutations (Polgamma(D257A/D257A) ...
Source: Experimental Gerontology - January 12, 2009 Category: Geriatrics Authors: Jang YC, Remmen HV Tags: Exp Gerontol Source Type: journals

VITO-2, a new SID domain protein, is expressed in the myogenic lineage during early mouse embryonic development.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MCAT elements and its cognate binding partners, the transcription enhancer factors (TEFs) play important roles in the regulation of expression of several muscle-specific genes. The biological effects of TEFs strongly depend on different co-factors, which might act as co-activators or anti-repressors to enable transcriptional activation of target genes by TEFs. Previously, we have cloned and characterized VITO-1, which acts as a skeletal muscle-specific transcriptional co-activator of TEFs. Here we describe the cloning and expression profile of a related gene, VITO-2 (also termed Vgl-3), which shares a high homology wit...
Source: Gene Expression Patterns : GEP - December 11, 2008 Category: Genetics & Stem Cells Authors: Mielcarek M, Piotrowska I, Schneider A, Günther S, Braun T Tags: Gene Expr Patterns Source Type: journals

Cloning, expression, crystallization and preliminary X-ray crystallographic analysis of malonyl-CoA–acyl carrier protein transacylase (FabD) from Xanthomonas oryzae pv. oryzaeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Xanthomonas oryzae pv. oryzae (Xoo) causes bacterial blight in rice, which is one of the most devastating diseases in rice-cultivating countries. The Xoo0880 (fabD) gene coding for a malonyl-CoA–acyl carrier protein transacylase (MCAT) from Xoo was cloned and expressed in Escherichia coli. MCAT is an essential enzyme that catalyzes a key reaction of fatty-acid synthesis in bacteria and plants: the conversion of malonyl-CoA to malonyl-acyl carrier protein. The FabD enzyme was purified and crystallized in order to elucidate its three-dimensional structure and to determine its enzymatic reaction mechanism and biological imp...
Source: Acta Crystallographica Section F - November 28, 2008 Category: Biochemistry Authors: Jung, J.-W.Natarajan, S.Kim, H.Ahn, Y.-J.Kim, S.Kim, J.-G.Lee, B.-M.Kang, L.-W. Tags: bacterial blight Xanthomonas oryzae pv. oryzae FabD antibacterial drugs crystallization communications Source Type: journals

Effect of the use of instructional anatomy videos on student performanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study is to describe the design, usage, and effect on examination performance of eight locally developed instructional anatomy videos. First-year UCSF medical students (n = 141) had access to the videos. They reported their video usage, reason for usage, and satisfaction. The prior year students (n = 141) served as a historical control group. Anatomy and radiology examination performance was compared between groups while controlling for prior performance. The students with and without access to the videos did not differ in examination performance. Sixty-one (43%) students in the experimental group res...
Source: Anatomical Sciences Education - July 18, 2008 Category: Anatomy Authors: Varun Saxena, Pradeep Natarajan, Patricia S. O'Sullivan, Sharad Jain Tags: Research Reports Source Type: journals

Acceleration of Monte Carlo-based scatter compensation for cardiac SPECT.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Single proton emission computed tomography (SPECT) images are degraded by photon scatter making scatter compensation essential for accurate reconstruction. Reconstruction-based scatter compensation with Monte Carlo (MC) modelling of scatter shows promise for accurate scatter correction, but it is normally hampered by long computation times. The aim of this work was to accelerate the MC-based scatter compensation using coarse grid and intermittent scatter modelling. The acceleration methods were compared to un-accelerated implementation using MC-simulated projection data of the mathematical cardiac torso (MCAT) phantom ...
Source: Physics in Medicine and Biology - June 23, 2008 Category: Physics Authors: Sohlberg A, Watabe H, Iida H Tags: Phys Med Biol Source Type: journals

Selective effects of 8-Br-cAMP on agonists and antagonists of the glucocorticoid receptorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract RU486 has been reported to be a glucocorticoid receptor (GR) and a progesterone receptor (PR) antagonist. We have analysed RU486 activity on the GR in WCL-2 (CHO) cells and in COS-7 cells transiently transfected with the mouse GR and with the reporter MMTVCAT (MCAT). These cell lines do not contain any active progesterone or androgen receptors. In both cell lines RU486 is a partial agonist of the GR with 10–15% of the activity of dexamethasone. As expected, RU486 is also a partial antagonist of the GR. Treatment of COS-7 cells with 8-Br-cAMP increases the agonist activity of both dexamethasone and...
Source: Endocrine - June 15, 2008 Category: Endocrinology Tags: Endocrine Source Type: journals

Aptitude, achievement and competence in medicine: a latent variable path modelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To develop and test a latent variable path model of general achievement, aptitude for medicine and competence in medicine employing data from the Medical College Admission Test (MCAT), pre-medical undergraduate grade point average (UGPA) and demographic characteristics for competence in pre-clinical and measures of competence (United States Licensure Examination {USMLE} Steps 1, 2, and 3). Data were gathered on 839,710 participants from 1991 to 2000 on demographic and school variables, UGPA, MCAT subtest scores and Steps 1, 2, and 3 of the United Stated Licensure Examination (USMLE). However, s...
Source: Advances in Health Sciences Education - May 15, 2008 Category: Universities & Medical Training Tags: Advances in Health Sciences Education Source Type: journals

Applying to Medical School: Preparing for the MCAT - Part 2 (NIH Only)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Presented by: Dr. William Higgins, University of MarylandCategory: NIH OnlyAired date: 01/24/2008 (Source: Videocast - All Events)
Source: Videocast - All Events - January 25, 2008 Category: Journals (General) Tags: Past Events Source Type: events

[EDUCATION FORUM] ASSESSMENT: Application of Bloom's Taxonomy Debunks the MCAT MythEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Analyses of questions that evaluate critical thinking, from college placement and medical school admission examinations, suggest improvements to college teaching methods.Analyses of questions that evaluate critical thinking, from college placement and medical school admission examinations, suggest improvements to college teaching methods.Authors: Alex Y. Zheng, Janessa K. Lawhorn, Thomas Lumley, Scott Freeman (Source: Science: Current Issue)
Source: Science: Current Issue - January 25, 2008 Category: Science Authors: Alex Y. Zheng Source Type: journals

Applying to Medical School: Preparing for the MCAT - Part I (NIH Only)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Presented by: Dr. William Higgins, University of MarylandCategory: NIH OnlyAired date: 01/16/2008 (Source: Videocast - All Events)
Source: Videocast - All Events - January 16, 2008 Category: Journals (General) Tags: Past Events Source Type: events

Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretrovirusesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Virus entry and virus-induced syncytium formation using the CAT-1 receptor are mediated by a small number of critical amino acid residues in receptor and virus Env. Virus entry is modulated by glycosylation of cellular proteins, and this effect is cell and virus-specific. (Source: Retrovirology)
Source: Retrovirology - January 10, 2008 Category: Virology Authors: Yuhe Yan, Yong T. Jung, Tiyun Wu and Christine A. Kozak Source Type: journals

Applying to Medical School: Preparing for the MCAT - Part 2 (NIH Only)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Workshop Description: Strategies for attacking the different sections of the MCAT. How to study, Deciding what to study, Test Day!, Final preparations, “Do’s” and “Don’ts”, procedures. Presenter: Dr. William Higgins, Associate Professor of Biology, University of Maryland, College Park and pre-professional adviserAir date: 1/24/2008 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 7, 2008 Category: Journals (General) Tags: Upcoming Events Source Type: events

Applying to Medical School: Preparing for the MCAT - Part I (NIH Only)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Workshop Description: Insights into the application process and application evaluation for medical school. How will your MCAT test score affect your likelihood of being accepted? When should you take the test? What is the test like: sections, content, types of questions? Presenter: Dr. William Higgins, Associate Professor of Biology, University of Maryland, College Park and pre-professional adviserAir date: 1/16/2008 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 7, 2008 Category: Journals (General) Tags: Upcoming Events Source Type: events

Analysis of factors that predict clinical performance in medical schoolEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Academic achievement indices including GPAs and MCAT scores are used to predict the spectrum of medical student academic performance types. However, use of these measures ignores two changes influencing medical school admissions: student diversity and affirmative action, and an increased focus on communication skills. To determine if GPA and MCAT predict performance in medical school consistently across students, and whether either predicts clinical performance in clerkships. A path model was developed to examine relationships among indices of medical student performance during the first three year...
Source: Advances in Health Sciences Education - November 21, 2007 Category: Universities & Medical Training Tags: Advances in Health Sciences Education Source Type: journals

Impact of preadmission variables on USMLE step 1 and step 2 performanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The results have implications that could impact the selection of applicants to medical school and the neural networks that we developed could be used in a prospective manner. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10459-007-9087-xAuthors James Kleshinski, The University of Toledo College of Medicine Department of Medicine Health Science Campus, Mail Stop 1186, 3000 Arlington Avenue Toledo OH 43614-2598 USASadik A. Khuder, The University of Toledo College of Medicine Department of Medicine Health Science Campus, Mail Stop 1186, 3000 Arlington Avenue Toledo OH 43614-2598 USAJoseph...
Source: Advances in Health Sciences Education - November 7, 2007 Category: Universities & Medical Training Tags: Advances in Health Sciences Education Source Type: journals

Fast multislice mapping of the myelin water fraction using multicompartment analysis of T2* decay at 3T: a preliminary postmortem study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, multicompartment analysis of T(2)(*) decay (MCAT(2)(*)) was used for the quantitative mapping of myelin water fraction (MWF). T(2)(*) decay of each voxel at multiple slice locations was acquired in fixed human brains using a multigradient-echo (MGRE) pulse sequence with alternating readout gradient polarities. Compared to prior techniques using Carr-Purcell-Meiboom-Gill (CPMG) acquisition, the MGRE acquisition approach has: 1) a very short first echo time ( approximately 2 ms) and echo-spacing ( approximately 1 ms), which allows for the acquisition of multiple sampling points during the fast decay of the mye...
Source: Magnetic Resonance in Medicine - November 1, 2007 Category: Radiology Authors: Du YP, Chu R, Hwang D, Brown MS, Kleinschmidt-DeMasters BK, Singel D, Simon JH Tags: Magn Reson Med Source Type: journals

Record number vied for 2007-08 medical school slotsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Among allopathic applicants, MCAT scores were better than ever before, with a mean of 28 points. (Source: American Medical News)
Source: American Medical News - October 29, 2007 Category: Journals (General) Tags: Profession Source Type: news

High Cancer-Specific Expression of Mesothelin (MSLN) Is Attributable to an Upstream Enhancer Containing a Transcription Enhancer Factor Dependent MCAT MotifEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Identification of genes with cancer-specific overexpression offers the potential to efficiently discover cancer-specific activities in an unbiased manner. We apply this paradigm to study mesothelin (MSLN) overexpression, a nearly ubiquitous, diagnostically and therapeutically useful characteristic of pancreatic cancer. We identified an 18-bp upstream enhancer, termed CanScript, strongly activating transcription from an otherwise weak tissue-nonspecific promoter and operating selectively in cells having aberrantly elevated cancer-specific MSLN transcription. Introducing mutations into CanScript showed two functionally disti...
Source: Cancer Research - October 1, 2007 Category: Cancer & Oncology Authors: Hucl, T., Brody, J. R., Gallmeier, E., Iacobuzio-Donahue, C. A., Farrance, I. K., Kern, S. E. Tags: Molecular Biology, Pathobiology, and Genetics Source Type: journals

Dean Reece Delivers His First State of the School AddressEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dean E. Albert Reece, MD, PhD, MBA gave his first State of the School address September 25 in front of a standing-room-only crowd in the MSTF auditorium. The theme was "Soaring to Greater Heights, Together." In his speech, the dean compared the School of Medicine to the majestic eagle, who will continue to fly in the face of all kinds of adversity, just as the school continues to succeed despite continuing challenges. After reviewing the highlights of his first year as dean of the School of Medicine, including special segments on bicentennial events and faculty accomplishments, Dean Reece got down to business...
Source: University of Maryland School of Medicine News Headlines - September 26, 2007 Category: Universities & Medical Training Source Type: news

A validity generalization perspective on the ability of undergraduate GPA and the medical college admission test to predict important outcomes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: A validity generalization perspective of the literature supports the use of MCAT and undergraduate GPA for selection to medical school. PMID: 17564535 [PubMed - indexed for MEDLINE] (Source: Teaching and Learning in Medicine)
Source: Teaching and Learning in Medicine - September 8, 2007 Category: Universities & Medical Training Authors: Kreiter CD, Kreiter Y Tags: Teach Learn Med Source Type: journals

Moderate anxiety, whether acute or chronic, is not associated with ovarian suppression in healthy, well-nourished, Western womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a two-part study of the relationship between moderate anxiety, both acute and chronic, and daily measures of ovarian steroid and corticosteroid levels in saliva. Anxiety, as a particular form of psychosocial stress, was measured by the Spielberger Stait-Trait Anxiety Inventory as well as by a self-reported daily stress score. In the first part, 23 college juniors taking the Medical College Admissions Test (MCAT) were studied the month before and the month after the test, and again several months later, and compared at the same time points with 27 controls. In the second part, chronic anxiety levels were assessed...
Source: American Journal of Physical Anthropology - September 4, 2007 Category: Physiology Authors: Peter T. Ellison, Susan F. Lipson, Gazyna Jasienska, Pippi L. Ellison Source Type: journals

A Validity Generalization Perspective on the Ability of Undergraduate GPA and the Medical College Admission Test to Predict Important OutcomesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Teaching and Learning in Medicine Volume 19, Issue 2, Page 95-100, Apr 2007. (Source: Teaching and Learning in Medicine)
Source: Teaching and Learning in Medicine - June 12, 2007 Category: Universities & Medical Training Source Type: journals

[ARTICLES] Malonyl-CoA: acyl carrier protein transacylase from Helicobacter pylori: Crystal structure and its interaction with acyl carrier proteinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, the crystal structure of MCAT from Helicobacter pylori (Hp) at 2.5 Å resolution is reported, and the interaction of HpMCAT with HpACP is extensively investigated by using computational docking, GST-pull-down, and surface plasmon resonance (SPR) technology-based assays. The crystal structure results reveal that HpMCAT has a compact folding composed of a large subdomain with a similar core as in /ß hydrolases, and a similar ferredoxin-like small subdomain as in acylphosphatases. The docking result suggests two positively charged areas near the entrance of the active site of HpMCAT as the ACP-bindin...
Source: Protein Science - May 24, 2007 Category: Biochemistry Authors: Zhang, L., Liu, W., Xiao, J., Hu, T., Chen, J., Chen, K., Jiang, H., Shen, X. Tags: ARTICLES Source Type: journals

A recessive genetic screen for host factors required for retroviral infection in a library of insertionally mutated Blm-/- ES cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This recessive genetic approach for identifying critical genes required for retroviral infection in ES cells demonstrates the feasibility and reliability of the screen, and provides a unique approach to recover other cellular factors required for retroviral infection. The resulting insertionally mutated Blm-deficient ES cell library might also provide access to essential host-cell components required for infection and replication of other types of virus. (Source: Genome Biology)
Source: Genome Biology - April 3, 2007 Category: Stem Cells Authors: Wei Wang and Allan Bradley Source Type: journals

Ligand presentation on a synthetic flexible hinge in Moloney murine leukemia virus SU supports entry via a heterologous receptor.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The envelope protein of Moloney murine leukemia virus mediates entry into mCAT-expressing cells. Attempts to change its receptor usage through the insertion of ligands at various sites have been met with varying success. We have tested several sites in Env for insertion of apelin, a small peptide ligand of the G-protein-coupled receptor APJ. Although most of the chimeric envelopes had retained their ability to infect mouse cells none showed APJ-dependent entry. Insertion of a peptide linker Ser-Gly-Gly-Ser-Gly at either side of the apelin motif in one of the chimeric envelopes resulted in an ability of the chimeric env...
Source: Virology - February 27, 2007 Category: Virology Authors: Bahrami S, Duch M, Pedersen FS Tags: Virology Source Type: journals

The Predictive Validity of the MCAT for Medical School Performance and Medical Board Licensing Examinations: A Meta-Analysis of the Published Research.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: ACADEMIC MEDICINE)
Source: ACADEMIC MEDICINE - January 20, 2007 Source Type: journals

JAMA Highlights the School of Medicine's BicentennialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Reprinted from JAMA, January 3, 2007—Vol 297) By Lynne Lamberg In early December 1807, a mob opposed to dissection of human bodies razed the building where Baltimore surgeon John B. Davidge, MD, was teaching anatomy to aspiring physicians. The crowd carried off the cadaver. Outrage over the rampage spurred introduction of a resolution in the Maryland General Assembly to establish a medical college in Baltimore. At the time, Maryland had fewer than 50 medically trained physicians. Delegates swiftly approved the bill. On December 18, 1807, the Assembly chartered the College of Medicine of Maryland, now the University ...
Source: University of Maryland School of Medicine News Headlines - January 11, 2007 Category: Universities & Medical Training Source Type: news

Ruling: MCAT must adapt for learning disabledEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Students who sued say the California decision could move other testing agencies to provide similar arrangements. The AAMC plans to appeal. (Source: American Medical News - PROFESSION)
Source: American Medical News - PROFESSION - November 20, 2006 Category: American Health Source Type: news

[Molecular Basis Of Cell and Developmental Biology] Transcription Enhancer Factor-1-dependent Expression of the {alpha}-Tropomyosin Gene in the Three Muscle Cell TypesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study represents the first analysis of the transcriptional regulation of the -Tm gene in vivo and highlights a common TEF-1-dependent regulatory mechanism necessary for expression of the gene in the three muscle lineages. (Source: Journal of Biological Chemistry)
Source: Journal of Biological Chemistry - November 3, 2006 Category: Chemistry Authors: Pasquet, S., Naye, F., Faucheux, C., Bronchain, O., Chesneau, A., Thiebaud, P., Theze, N. Source Type: journals

The Inner Life of the CellEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Here's some fantastic animation by XVIVO, LLC, a Connecticut based scientific visualization company. Developed for Harvard's Department of Molecular and Cellular Biology, to illustrate "a three-dimensional journey through the microscopic world of a cell", the animation was recently featured at Siggraph 2006 expo. This seems to be a collection of clips to illustrate a larger set of work, which we hope will help Harvard students do better than they have on their MCATs in the coming years. Many more animations can be viewed on company's website... UPDATE: XVIVO also offers a first-person shooter game designed to promote Genen...
Source: Medgadget - August 16, 2006 Category: Technology Consultants Source Type: info

A Commentary on the Use of Cut-Scores to Increase the Emphasis of Non-Cognitive Variables in Medical School AdmissionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The academic performance consequences of relying solely on non-cognitive factors for selecting applicants above a GPA and MCAT threshold have not been fully considered in the literature. This commentary considers the impact of using a “threshold approach” on academic performance as assessed with the USMLE Step 1. Content TypeJournal Article JournalAdvances in Health Sciences EducationOnline ISSN 1573-1677Print ISSN 1382-4996 (Source: Advances in Health Sciences Education)
Source: Advances in Health Sciences Education - August 8, 2006 Category: Universities & Medical Training Source Type: journals