Healthy aging among centenarians and near-centenarians: Findings from the Georgia Centenarian Study
Living a long, satisfactory, and healthy life is a goal most, if not all, adults strive to attain. Demographic trends in all developed countries show that average life spans gradually get longer, and more adults live longer past the century mark [1]. As people live longer, more scientific studies are being conducted to unmask the underlying mechanisms that can contribute to living longer and well --- that is, healthy aging [2]. (Source: Maturitas)
Source: Maturitas - April 18, 2024 Category: Primary Care Authors: Peter Martin, Leonard W. Poon, for the Georgia Centenarian Study Tags: Review article Source Type: research
Culturally responsive care for menopausal women
Over 6 million women worldwide enter menopause annually [1]. Although menopause is a universal physiologic phenomenon, women experience, respond to, and seek care for menopause in different ways. This is because of the complex interactions between biological, physiologic, psychological, social, and cultural factors [2 –7]. Culture includes customs; language; values; and social, religious, racial, or ethnic identities, actions, and beliefs. All of these factors inform individuals' perceptions, general health behaviors, care-seeking, and symptom management [6,8]. (Source: Maturitas)
Source: Maturitas - April 17, 2024 Category: Primary Care Authors: Makeba Williams Tags: Review article Source Type: research
Menopause hormone therapy prescribing in ambulatory care visits among midlife and older U.S. women from 2018 to 2019
Menopause hormone therapy (HT) is indicated for the treatment of vasomotor symptoms of menopause, premature menopause, genitourinary syndrome of menopause, and prevention of osteoporosis [1]. After the 2002 Women's Health Initiative (WHI) study results were published, HT prescribing rates plummeted 66 % amidst fears of cardiovascular disease, venous thromboembolism, and breast cancer [2]. In 2009–2010, the prevalence of HT use was 4.7 %, decreased from 22.4 % in 1999–2000 [3]. Almost no recent studies have reported HT prescribing rates in representative patient samples in the U.S. (Source: Maturitas)
Source: Maturitas - April 17, 2024 Category: Primary Care Authors: Talia H. Sobel, Nadra E. Lisha, Alison J. Huang Tags: Short communication Source Type: research
Sexual function in women with premature ovarian insufficiency (POI): Systematic review and meta-analysis
Premature ovarian insufficiency (POI), also known as premature menopause or in former days as premature ovarian failure, is a condition in which the ovaries stop functioning before the age of 40 [1]. POI lacking a clear cause is classified as [1]. POI is a life-changing diagnosis with profound physical and psychological consequences [2]. The majority of the women with POI, suffer from hot flashes, night sweats, insomnia, depression and anxiety. The impact of POI on sexual complaints is large: many women report vaginal dryness, dyspareunia (painful intercourse), and diminished libido [3]. (Source: Maturitas)
Source: Maturitas - April 17, 2024 Category: Primary Care Authors: Charissa van Zwol-Janssens, Hester Pastoor, Joop S.E. Laven, Yvonne V. Louwers, Geranne Jiskoot Tags: Review article Source Type: research
Risks and benefits of hormone therapy after menopause for cognitive decline and dementia: A conceptual review
The evidence and our beliefs about the beneficial or harmful effects of hormone therapy (HT) on brain aging have changed quite dramatically over time. In the last five years, several observational studies have shown an increased risk of dementia in women who had received HT [1 –5]. However, these results are opposite to the results of several observational studies and some clinical trials published over the last 30 years [6,7]. Therefore, in a 2022 editorial, we suggested that the answer to the simple question: “Is HT protective or harmful for cognitive decline and dementia?” is actually quite complex and may vary ...
Source: Maturitas - April 16, 2024 Category: Primary Care Authors: Walter A. Rocca, Kejal Kantarci, Stephanie S. Faubion Tags: Review article Source Type: research
Attitudes and practice patterns of Finnish obstetrician-gynecologists regarding patients' sexual problems
Sexuality is an important aspect of quality of life [1,2]. However, sexual problems are common, with the prevalence of female sexual dysfunction (FSD) ranging from 40 % to 50 %, irrespective of age [3]. Many different health care professionals—for instance, certified nurses, sexuality educators, sexuality counselors, and sexuality therapists, as well as physicians in various fields—take part in the management of sexual problems. Obstetrician-gynecologist s (OB/GYNs) are some of the key health care professionals who diagnose and treat female sexual problems, but previous studies have reported that OB/GYNs underesti...
Source: Maturitas - April 12, 2024 Category: Primary Care Authors: Anna Aromaa, P äivi Polo-Kantola, Sanna-Mari Manninen, Jarna Grönlund, Markus Riskumäki, Tero Vahlberg, Katja Kero Tags: Original article Source Type: research
Imaging and molecular features of adenomyosis after menopause
Adenomyosis is a benign gynecological disorder, characterized by the presence of endometrial epithelium (stroma and glands) within the myometrium, surrounded by smooth muscle hyperplasia [1]. The impaired expression of genes related to epithelial-mesenchymal transition, inflammation and fibrosis has been shown in adenomyotic lesions [2 –4]. The clinical presentation may include heavy menstrual bleeding (HMB), pelvic pain, dysmenorrhea, infertility and recurrent pregnancy loss [5,6]. (Source: Maturitas)
Source: Maturitas - April 11, 2024 Category: Primary Care Authors: Silvia Vannuccini, Silvia Gabbrielli, Francesca Castiglione, Eleonora Nardi, Margherita Rossi, Gretha Orlandi, Elisa Wu, Francesca Bertoli, Vittorio Miele, Chiara Donati, Felice Petraglia Tags: Original article Source Type: research
Editorial Board
(Source: Maturitas)
Source: Maturitas - April 5, 2024 Category: Primary Care Source Type: research
Hormone therapy in women with benign breast disease – What little is known and suggestions for clinical implementation
Benign breast disease encompasses a spectrum of non-malignant conditions within the breast, characterized by variations in both histological features and clinical manifestations. These conditions can be categorized into non-proliferative lesions, proliferative lesions without atypia, and proliferative lesions with atypia, each of which carries differing degrees of risk for future breast cancer development. The increased utilization of screening mammography has notably contributed to the rising detection of these lesions over the years [1]. (Source: Maturitas)
Source: Maturitas - April 5, 2024 Category: Primary Care Authors: Sabrina K. Sahni, Jessica L. Fraker, Lauren F. Cornell, Christine L. Klassen Tags: Review article Source Type: research
Menopause in the workplace: Challenges, impact, and next steps
Work Ability Index (Source: Maturitas)
Source: Maturitas - April 2, 2024 Category: Primary Care Authors: Nancy Safwan, Mariam Saadedine, Chrisandra L. Shufelt, Ekta Kapoor, Juliana M. Kling, Rajeev Chaudhry, Stephanie S. Faubion Tags: Review article Source Type: research
Evaluation of muscle and bone composition and function in aging women with polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a complex hormonal and metabolic disorder affecting up to 20 % of women in reproductive years [1]. The syndrome is associated with several comorbidities, including type 2 diabetes mellitus, hepatosteatosis, dyslipidemia, hypertension, endometrial cancer, sleep disorders, depression, and anxiety [2,3]. (Source: Maturitas)
Source: Maturitas - March 31, 2024 Category: Primary Care Authors: Burcu Çelik Eroğlu, Levend Karaçoban, Ilkay S. Idılman, Feza Korkusuz, Bulent Okan Yıldız Tags: Original article Source Type: research
The effects of lifestyle and behavioural interventions on cancer recurrence, overall survival and quality of life in breast cancer survivors: A systematic review and network meta-analysis
Breast cancer is the most prevalent malignancy and the leading cause of death from cancer among women, comprising 24.2 % of new cancer cases and 15 % of cancer deaths globally [1]. Advances in early diagnosis and treatment contribute to a 90 % 5-year relative survival rate, underscoring the importance of tailored survivorship care for women with breast cancer [2]. (Source: Maturitas)
Source: Maturitas - March 29, 2024 Category: Primary Care Authors: Ladan Yeganeh, Suzanne Willey, Ching Shan Wan, Mahnaz Bahri Khomami, Mohammad Chehrazi, Olivia Cook, Kate Webber Tags: Review article Source Type: research
An effective non-hormonal option with high tolerability for mild to moderate symptoms of vaginal dryness associated with menopause
Vaginal dryness is a typical and bothersome atrophic symptom of women with genitourinary syndrome of menopause (GSM). This chronic-progressive condition becomes clinically apparent some years after the onset of menopause [1]. As the average age of natural menopause ranges from 51 to 52 years in Germany and other industrialized countries, women over 50 years of age are most at risk of being affected by GSM [2]. Even though vaginal dryness can occur at any age, it specifically concerns women in the postmenopausal phase with a prevalence rate of>50 % [1,3,4]. (Source: Maturitas)
Source: Maturitas - March 28, 2024 Category: Primary Care Authors: Susann Eichler, Mareike Panz, Anastasia Harder, Clarissa Masur, Manuel H äuser, Erik Schulze zur Wiesche Tags: Original article Source Type: research
Moderate-intensity continuous training and high-intensity interval training modulate the composition of the oral microbiota of elderly adults: Randomized controlled trial
Joshua Lederberg, a geneticist and Nobel prize laureate in 1958, first coined the term microbiome as a community of commensal, symbiotic, and pathogenic micro-organisms [1]. The microbial colonization of the human body starts before birth, with a primary fetal colonization [2], then, the diversity, stability, and complexity evolves influenced by age, sex, development of the immune system and environmental factors for three years. Afterwards, the microbial colony remains stable in healthy adults and becomes unstable again when elderly. (Source: Maturitas)
Source: Maturitas - March 24, 2024 Category: Primary Care Authors: Mar ía Leyre Lavilla-Lerma, Agustín Aibar-Almazán, Antonio Martínez-Amat, José Daniel Jiménez-García, Fidel Hita-Contreras Tags: Original article Source Type: research
Association of age at menarche, reproductive lifespan and age at menopause with the risk of atrial fibrillation: The HUNT study
Age at menarche, reproductive lifespan, and age at menopause are associated with several cardiovascular diseases, but their relationship with atrial fibrillation (AF) is uncertain. (Source: Maturitas)
Source: Maturitas - March 24, 2024 Category: Primary Care Authors: Hikaru Morooka, Eirin B. Haug, Vegard Malmo, Jan P ål Loennechen, Kenneth Mukamal, Janet Rich-Edwards, Abhijit Sen, Imre Janszky, Julie Horn Tags: Original article Source Type: research
