Medscape Gastroenterology Headlines
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Genetic Predictors of Treatment-Induced Viral Clearance in Hepatitis C
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Drs. Dermot McGovern and Gil Melmed comment on a study published in Nature on the ability of an IL-28B polymorphism to predict sustained viral response to hepatitis C treatment. Medscape Genomic Medicine (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 18, 2009 Category: Gastroenterology Tags: Pathology & Lab Medicine Source Type: info
Occult Hepatitis B Virus Infection Increases Hepatocellular Carcinogenesis by Eight Times in Patients With Non-B, Non-C Liver Cirrhosis: A Cohort Study
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This study takes a look. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 12, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Ulcerative Colitis Maintenance Treatment With 5-ASA: A 1-Year, Randomized Multicentre Study Comparing MMX With Asacol
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Investigators evaluated the efficacy and safety of 5-ASA-MMX (2.4 g/d qd) compared with Asacol (2.4 g/d, bid) in the maintenance of left-sided ulcerative colitis. Alimentary Pharmacology & Therapeutics (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 10, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Analysis of the Efficacy of Treatment With Peginterferon Alpha-2a and Ribavirin in Patients Coinfected With Hepatitis B Virus And Hepatitis C Virus
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Investigators examined the virologic features of patients coinfected with HBV and HCV and the efficacy of combination therapy with peginterferon alpha-2a and ribavirin in these patients. Liver International (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 6, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
HBV Reduces Recurrence-Free Survival After Surgery for Hepatocellular Carcinoma
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In cirrhotic patients, hepatitis B virus (HBV) infection is associated with a poorer long-term prognosis after hepatectomy for hepatocellular carcinoma, according to Italian researchers. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 5, 2009 Category: Gastroenterology Tags: General Surgery Source Type: info
Children's Hospitals Often Do Not Follow Gastroenteritis Guidelines
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Children's hospitals in the US commonly use resources not routinely recommended by published guidelines for the management of acute gastroenteritis, according to results of a study published online Monday in Pediatrics. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 3, 2009 Category: Gastroenterology Tags: Pediatrics Source Type: info
LAC and LOAD: 4-Drug Regimen Better at Eliminating H Pylori Than Standard 3-Drug Treatment
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LOAD (levofloxacin, omeprazole, nitazoxanide, and doxycycline) is more effective at eradicating Helicobacter pylori than LAC (lansoprazole, amoxicillin, and clarithromycin). Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 2, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
The Correlation of Hepatocyte Nuclear Factor 4 Alpha and 3 Beta With Hepatitis B Virus Replication in the Liver of Chronic Hepatitis B Patients
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This study assessed the relationship between HNF4alpha and HNF3beta expression in the liver tissue of chronic HBV-infected patients and that between HNF4alpha and HNF3beta levels and HBV replication. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 29, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Vaccination Program Cuts HBV Infection in Children of Foreign-Born Asian Parents
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The hepatitis B virus (HBV) infant vaccination program in the US appears to have reduced chronic infection, morbidity and mortality among populations at high risk, a paper in the October 9th issue of the journal Vaccine suggests. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 26, 2009 Category: Gastroenterology Tags: Allergy & Clinical Immunology Source Type: info
RIFLE Classification as Predictive Factor of Mortality in Patients With Cirrhosis Admitted to Intensive Care Unit
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Investigators assessed the association of the Risk, Injury, Failure, Loss and End-stage renal failure (RIFLE) score on mortality in patients with decompensated cirrhosis admitted to ICU. Journal of Gastroenterology and Hepatology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 22, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Antiviral Resistance and Specifically Targeted Therapy for HCV (STAT-C)
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This article focuses on the current literature concerning resistance and directly acting antiviral agents and identifies key challenges facing the treatment of chronic hepatitis C infection. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 22, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Implication of Normal Liver Enzymes in Liver Disease
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This article suggests future research should focus on alternative noninvasive markers of liver damage vs. ALT levels, given many individuals have significant liver disease but normal ALT levels. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 22, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Impact of Obesity, Steatosis and Insulin Resistance on Progression and Response to Therapy of Hepatitis C
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This review article focuses on some of the current knowledge on and management of the clinical consequences of overweight/obesity, steatosis, and insulin resistance on chronic HCV. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 15, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Predictors of Antiviral Treatment Initiation in Hepatitis C Virus-Infected Patients: A Danish Cohort Study
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Investigators sought to determine predictive factors for initiation of treatment with standard or pegylated interferon either alone or combined with ribavirin in patients with HCV infection. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 15, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Association Study of IFNAR2 and IL10RB Genes With the Susceptibility and Interferon Response in HBV Infection
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This study reassessed the effects of the 2 polymorphisms IFNAR-2 F8S and IL10RB K47E on HBV susceptibility in Chinese Han and assessed their association with IFN response in chronic HBV. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 15, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
A 2-Log Drop in Viral Load at 1 Month Is the Best Predictor of Sustained Response in HCV Patients With Normal ALT: A Kinetic Prospective Study
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Investigators sought to determine a reliable predictor of a sustained virologic response in patients with hepatitis C infection and a persistently normal ALT. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 15, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Chronic Hepatitis B and C: Update on Therapy
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What are some new treatment strategies for patients with chronic HBV and HCV infections? Future Virology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 14, 2009 Category: Gastroenterology Tags: Infectious Diseases Source Type: info
Diet Supplements Do Not Affect Colorectal Cancer Markers
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Use of prebiotic, probiotic, and synbiotic dietary supplementation leads to changes in fecal microflora but not to variables associated with colorectal cancer, according to Australian and US researchers. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 9, 2009 Category: Gastroenterology Tags: Hematology-Oncology Source Type: info
GI Tract Findings Common With Obstructive Sleep Apnea, Snoring
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Upper gastrointestinal tract pathology appears to be the norm, not the exception, in patients with obstructive sleep apnea (OSA) and in people who only snore, a small study suggests. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 8, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Older Age Linked to Colonoscopic Perforation
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People over 75 years who undergo colonoscopy or flexible sigmoidoscopy are six times more likely to experience a colon perforation than younger individuals, according to findings from Thailand. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 8, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Gastroesophageal Reflux and Insomnia
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Sleep-related GER disrupts sleep, causes insomnia, and is associated with daytime functional impairment. AccessMedicine from McGraw-Hill (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 7, 2009 Category: Gastroenterology Tags: Internal Medicine Source Type: info
Most Foreign-Born Children Should Be Screened for Hepatitis B, New Guidelines Say
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A panel convened by the Hepatitis B Foundation released recommendations on Monday governing the screening, monitoring, and referral of children with chronic hepatitis B. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 6, 2009 Category: Gastroenterology Tags: Pediatrics Source Type: info
Proton-Pump Inhibitors and Clopidogrel: Back to the Future?
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Recommendations to avoid proton-pump inhibitors in patients on antiplatelet therapy may have gone too far. Find out why. Medscape Gastroenterology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 5, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
"Substantial" Toxicity With Peginterferon Use: FDA Staff
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Schering-Plough Corp's injectable drug PegIntron (peginterferon) carries "substantial toxicity" and had no effect on overall survival in melanoma skin cancer patients undergoing surgery, U.S. Food and Drug Administration staff reviewers said in documents released on Thursday. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 2, 2009 Category: Gastroenterology Tags: Public Health & Prevention Source Type: info
Vitamin C Use May Enhance H. Pylori Eradication Regimen
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Supplementation with vitamin C enhances the success of Helicobacter pylori eradication efforts, researchers from Iran report. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 2, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
International Society of Gastrointestinal Oncology (ISGIO) 6th Annual Meeting
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Read clinically focused news coverage of key developments from the meeting. Medscape Hematology-Oncology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 1, 2009 Category: Gastroenterology Source Type: info
Cholera/diarrhea Outbreak Hits 18,000 in Ethiopia
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Cholera and other diarrheal diseases have infected 18,000 people in Ethiopia over the last 3 weeks in many parts of the country, including the capital Addis Ababa, according to a document seen by Reuters. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 10, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Severe Gallstone Disease on the Rise in Taiwan
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Rates of hospitalization for severe gallstone disease have risen sharply in recent years among young adults in Taiwan. Older adults have experienced increases in biliary pancreatitis and acute cholangitis. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 10, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Meta-analysis Used to Identify Factors Associated With the Effectiveness of Proton Pump Inhibitors Against Non-erosive Reflux Disease
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Investigators conducted a meta-analysis of studies to identify factors associated with treatment response to PPIs in patients with nonerosive reflux disease. Journal of Gastroenterology and Hepatology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 9, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Adherence to a Low-Fat, High-Fiber Diet Lowers Risk of Polyp Recurrence
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Patients who strictly follow a low-fat, high-fiber, and high-fruit and -vegetable diet have a lower risk of colon adenoma recurrence. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 9, 2009 Category: Gastroenterology Tags: Hematology-Oncology Source Type: info
What's Your Practice Worth Today?
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Physicians who may want to sell their practices wonder whether their practices still have much value, given dropping reimbursements and more doctors becoming employees. Medscape Business of Medicine (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 4, 2009 Category: Gastroenterology Tags: Business of Medicine Source Type: info
Probiotic Drink May Not Prevent Antibiotic-Associated Diarrhea
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In a randomized controlled trial, kefir, a fermented milk product similar to yogurt but containing different fermentation microbes, did not prevent antibiotic-associated diarrhea. Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 25, 2009 Category: Gastroenterology Tags: Pediatrics Source Type: info
Hepatitis C Virus Impacts Survival After Liver Transplantation
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Liver transplant recipients whose indication for transplant was hepatitis C virus (HCV) cirrhosis have markedly poorer survival compared to patients transplanted for alcoholic liver disease (ALD), researchers have found. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 21, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Hepatitis C Virus Coinfection Ups Risk of HIV-Related Infections
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HIV-infected patients coinfected with hepatitis C virus are more than 3 times likely to have an HIV-related bacterial or mycotic infection vs patients without hepatitis C virus coinfection. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 15, 2009 Category: Gastroenterology Tags: HIV/AIDS Source Type: info
Salmonella and Campylobacter Gastroenteritis Increase IBD Risk
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Gastroenteritis from Salmonella or Campylobacter increases the odds of developing inflammatory bowel disease (IBD), with the risk persisting 15 years or more. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 14, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Drug Advertising Campaigns Influence Consumers and Doctors: Study
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The direct-to-consumer advertising campaign for the irritable bowel drug tegaserod (Zelnorm) led to a significant and immediate, although short-lived, spike in physician visits for abdominal pain, constipation and bloating as well as in diagnoses of irritable bowel syndrome (IBS), researchers have found. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 10, 2009 Category: Gastroenterology Tags: Business of Medicine Source Type: info
Covered Metal Stents Straight-Arm Benign Biliary Stricture
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Benign biliary strictures secondary to chronic pancreatitis can prove intractable to endoscopic management, but use of covered, removable metal stents is straightening out this therapeutic problem. Medscape Gastroenterology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 10, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Prognostic Indicators in Hepatocellular Carcinoma: A Systematic Review of 72 Studies
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This systematic review of 72 studies evaluated prognostic indicators in patients with cirrhosis and HCC, showing the most robust predictors of death in these individuals are tumor and liver related. Liver International (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 7, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Use of Ursodiol in Infants and Children
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Review recent studies conducted with ursodiol in infants and children with hepatobiliary diseases, as well the drug's mechanism of action, pharmacokinetics, and adverse effects. Pediatric Pharmacotherapy (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 6, 2009 Category: Gastroenterology Tags: Pediatrics Source Type: info
5-HT Agonists/antagonists May Improve Irritable Bowel Syndrome
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Some modulators of 5-hydroxytryptamine (5-HT) appear to be effective in relieving symptoms of irritable bowel syndrome (IBS), the results of a systematic review and meta-analysis indicate. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 5, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Biliary Dyskinesia
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This brief review provides current information, including a recent international consensus opinion to distinguish functional biliary disorders from other functional abdominal pain syndromes. AccessMedicine from McGraw-Hill (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 31, 2009 Category: Gastroenterology Tags: Internal Medicine Source Type: info
Abnormal Glucose Tolerance in Young Male Patients With Nonalcoholic Fatty Liver Disease
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This study demonstrated that young men with NAFLD, elevated liver enzymes, and an impaired fasting glucose should undergo an oral glucose tolerance test to predict their risk for type 2 diabetes. Liver International (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 31, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Role of Alcohol in Liver Carcinogenesis
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Chronic alcohol consumption has long been associated with progressive liver disease. It may also increase the risk of developing hepatocellular carcinoma, one of the most common malignant tumors. Seminars in Liver Disease (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 24, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Acid Peptic Diseases: Pharmacological Approach to Treatment
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Peptic ulcer disease afflicts several million people in the USA every year. Read this clinical update to learn about the current challenges in the treatment of acid-mediated diseases. Expert Review of Clinical Pharmacology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 22, 2009 Category: Gastroenterology Tags: Pharmacist Source Type: info
Is Lansoprazole Effective in Infants With Symptoms of GERD?
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A large randomized, placebo-controlled, blinded trial looks the effectiveness of this proton-pump inhibitor in infants. Medscape Pediatrics (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 18, 2009 Category: Gastroenterology Tags: Pediatrics Source Type: info
Low Affinity Glucocorticoid Binding Site Ligands as Potential Anti-fibrogenics
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What inhibits liver fibrosis? Comparative Hepatology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 16, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Pill Camera Not as Good as Colonoscopy for Detecting GI Lesions
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Compared with colonoscopy, capsule endoscopy has a low sensitivity for detecting polyps and cancers. However, one expert sees a future for it in cancer screening. Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 15, 2009 Category: Gastroenterology Tags: Hematology-Oncology Source Type: info
The Case | Hypokalemia Associated With Nephrocalcinosis
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Episodes of general weakness and abnormal liver function test several times in the past led to a a diagnosis of hepatitis, but a positive Schirmer test suggested Sjögren's syndrome. Kidney International (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 15, 2009 Category: Gastroenterology Tags: Nephrology Source Type: info
Update on Viral Hepatitis: 2008
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This is a concise review of recent developments in the field of viral hepatitis, based on publications between December 2007 and November 2008. Current Opinion in Gastroenterology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 14, 2009 Category: Gastroenterology Tags: Gastroenterology Source Type: info
Capecitabine/Cisplatin Versus 5-Fluorouracil/Cisplatin as First-Line Therapy in Patients With Advanced Gastric Cancer: A Randomised Phase III Noninferiority Trial
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Advanced gastric cancer treatment regimens are compared. Is capecitabine/cisplatin noninferior to 5-fluorouracil/cisplatin? Annals of Oncology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 14, 2009 Category: Gastroenterology Tags: Hematology-Oncology Source Type: info
