Medscape Hematology-Oncology Headlines
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Part 2: The Case of the Emergency Room Physician Who Burned Out: Diagnosing and Treating His Substance Abuse
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In part 2 of the new series on the Impaired Physician, substance abuse develops in Dr. X. Is it now time to turn him in? Medscape Internal Medicine (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 18, 2009 Category: Cancer & Oncology Tags: Internal Medicine Source Type: info
What Should Patients Do With Unused Narcotics?Email this article to a colleague.
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Clinicians often tell patients to save their remaining narcotics for "next time." According to guidelines, this may not be the best advice. Medscape Pharmacists (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 18, 2009 Category: Cancer & Oncology Tags: Pharmacist Source Type: info
Cetuximab and Radiotherapy: A Standard Option in Head and Neck Cancer?Email this article to a colleague.
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Five-year results show an absolute benefit of 9% for the combination of cetuximab and radiotherapy, compared with radiotherapy alone, in locoregional disease. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 16, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Sonic Hedgehog Signaling Proteins and ATP-Binding Cassette G2 Are Aberrantly Expressed in Diffuse Large B-Cell LymphomaEmail this article to a colleague.
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How does the expression of sonic hedgehog signaling proteins compare among diffuse large B-cell lymphoma, follicular lymphoma, and chronic lymphocytic leukemia? Modern Pathology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 13, 2009 Category: Cancer & Oncology Tags: Pathology & Lab Medicine Source Type: info
International Guidelines for Management of Metastatic Breast Cancer: Combination vs Sequential Single-Agent ChemotherapyEmail this article to a colleague.
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Using a combination of cytotoxic chemotherapies vs sequential single agents in metastatic breast cancer is controversial. The ESO-MBC Task Force provides guidelines and recommendations. Journal of the National Cancer Institute (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 10, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Primary Lung Cancer vs Metastatic Breast Cancer: A Probabilistic ApproachEmail this article to a colleague.
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Is it primary lung cancer or breast cancer metastatic to the lung? This mathematical and probabilistic model may help in the differential diagnosis. American Journal of Clinical Pathology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 10, 2009 Category: Cancer & Oncology Tags: Pathology & Lab Medicine Source Type: info
Radial Stereotactic Radiosurgery A New Option for Patients With Inoperable NSCLCEmail this article to a colleague.
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Patients with inoperable stage IA nonsmall-cell lung cancer (NSCLC) but good lung function who undergo radial stereotactic radiosurgery show good long-term overall survival rates. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 9, 2009 Category: Cancer & Oncology Tags: Pulmonary Medicine Source Type: info
MRI-Detected Suspicious Breast Lesions: Predictive Values of Kinetic Features Measured by Computer-Aided EvaluationEmail this article to a colleague.
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Computer-aided evaluation programs developed for breast MRI provide automated image processing and kinetic analysis and are increasingly used in clinical practice. But how useful are they? American Journal of Roentgenology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 6, 2009 Category: Cancer & Oncology Tags: Radiology Source Type: info
Adequate Cervical Tissue Sample Required to Assess p16 PositivityEmail this article to a colleague.
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Cervical tissue samples that are too small are not appropriate to assess for p16 positivity; the use of the p16 assay on limited samples could lead to the overdiagnosis of endocervical cancer. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 6, 2009 Category: Cancer & Oncology Tags: Pathology & Lab Medicine Source Type: info
"Striking Increase" in Papillary Thyroid Cancer in Volcanic AreaEmail this article to a colleague.
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The identification of the elements within the volcanic environment that might be responsible could eventually help in developing prevention measures, say researchers. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 6, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal CancerEmail this article to a colleague.
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Prospectively collected resource utilization and health utility data for patients with CRC in the CO.17 study who received best supportive care +/- cetuximab were assessed for cost effectiveness. Journal of the National Cancer Institute (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 3, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Effect of Human Papillomavirus on Cell Cycle-Related Proteins p16, Ki-67, Cyclin D1, p53, and ProEx C in Precursor Lesions of Cervical Carcinoma: A Tissue Microarray StudyEmail this article to a colleague.
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Immunohistochemical assessment of cell cycle proteins may help distinguish normal and benign conditions of the cervix from precursor lesions of cervical carcinoma. American Journal of Clinical Pathology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 3, 2009 Category: Cancer & Oncology Tags: Pathology & Lab Medicine Source Type: info
Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal Cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 TrialEmail this article to a colleague.
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Prospectively collected resource utilization and health utility data for patients with CRC in the CO.17 study who received best supportive care +/- cetuximab were assessed for cost effectiveness. Journal of the National Cancer Institute (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 3, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Can Doctors Ever Tell Patients They Are Cured of Cancer?Email this article to a colleague.
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In her first Medscape video blog, Dr. Kathy Miller asks whether doctors should avoid using the term “cured” to describe patients who have been in remission for several years. Medscape Hematology-Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 2, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Aspirin Confers Long-Term Protective Effect in Lynch Syndrome PatientsEmail this article to a colleague.
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Lynch syndrome patients enrolled in an "unsuccessful" trial are demonstrating lower rates of colorectal cancer 4 years after the aspirin study's initiation. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 2, 2009 Category: Cancer & Oncology Tags: Pathology & Lab Medicine Source Type: info
Iterative Reconstruction Technique for Reducing Body Radiation Dose at CT: Feasibility StudyEmail this article to a colleague.
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This study provides some answers. American Journal of Roentgenology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 30, 2009 Category: Cancer & Oncology Tags: Radiology Source Type: info
Nulliparity, Late Age at First Childbirth Linked to Aggressive Breast CancerEmail this article to a colleague.
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Nulliparity and late-life first childbirth are associated with more aggressive breast cancer, according to Swedish researchers. Reuters Health Information (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 29, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Association of Genetic Polymorphisms With Interferon-Induced Haematologic Adverse Effects in Chronic Hepatitis C PatientsEmail this article to a colleague.
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Investigators sought to identify host genetic polymorphisms associated with the efficacy or hematologic toxicity of IFN-based combination therapy in chronic hepatitis C patients. Journal of Viral Hepatitis (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 29, 2009 Category: Cancer & Oncology Tags: Gastroenterology Source Type: info
Peptide Vaccines for Patients With Acute Myeloid LeukemiaEmail this article to a colleague.
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What leukemia-associated antigen peptides might be useful in a vaccine to reduce the risk of relapse after chemotherapy or stem-cell transplantation? Expert Review of Vaccines (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 23, 2009 Category: Cancer & Oncology Tags: Infectious Diseases Source Type: info
Predicting Outcome in Melanoma: Where are we now?Email this article to a colleague.
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The purpose of this article was to review current and emerging data for predicating outcome in patients with melanoma. The British Journal of Dermatology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 21, 2009 Category: Cancer & Oncology Tags: Dermatology Source Type: info
Three-Dimensional Volume Rendering and Display of Skin and Subcutaneous TissuesEmail this article to a colleague.
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What is the clinical utility of volume-rendering techniques in the evaluation of skin ulcers, inflammation, trauma, and soft tissue tumors? Applied Radiology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 20, 2009 Category: Cancer & Oncology Tags: Radiology Source Type: info
Hidden Prostate Cancers May Be Detectable by MRIEmail this article to a colleague.
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When worrisome prostate cancer variables are present but patients have either negative biopsies or a low-volume tumor, magnetic resonance imaging (MRI) might uncover a hidden tumor. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 16, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Addition of FDG PET to the Work-up for Surgical Resection of Colorectal Liver MetastasesEmail this article to a colleague.
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Commentary on a study on whether the addition of FDG PET to the work-up for surgical resection of liver metastases can reduce futile laparotomies. Medscape Radiology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 12, 2009 Category: Cancer & Oncology Tags: Radiology Source Type: info
The Value of Final ExamsEmail this article to a colleague.
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In his latest video blog, Dr. John Marshall compares the work involved in writing successful grant proposals to the preparations necessary for final exams. Medscape Hematology-Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 8, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Pegylated Interferon for Melanoma Narrowly Recommended for FDA ApprovalEmail this article to a colleague.
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The vote was 6 to 4 in favor of recommending approval of a pegylated formulation of interferon alfa, which eliminates the need for intravenous infusions. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 7, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
PSA Test Is Imperfect Screening Tool: What to Do?Email this article to a colleague.
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The use of the prostate-specific antigen (PSA) test for population-based prostate cancer screening in the United States has led to gross overtreatment, but no other tests are currently available. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 1, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
A Single-Nucleotide Polymorphism in the MDR1 Gene as a Predictor of Response to Neoadjuvant Chemotherapy in Breast CanceEmail this article to a colleague.
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Investigators examined the frequency of SNP in exon 26 of the MDR1 gene in breast cancer and its role in predicting response to neoadjuvant chemotherapy in breast cancer. Clinical Breast Cancer (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 30, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Cancer Incidence Among Patients With Alcohol Use Disorders—Long-Term Follow-UpEmail this article to a colleague.
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Are patients with alcohol-use disorders more susceptible to developing cancer? Alcohol and Alcoholism (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 30, 2009 Category: Cancer & Oncology Tags: Psychiatry Source Type: info
Transplantation for Non-Hodgkin LymphomaEmail this article to a colleague.
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Investigators assessed the outcomes of auto-hematopoietic stem cell transplantation (HCT) and allo-HCT for various lymphomas, particulary non-Hodgkin lymphoma. Expert Review of Hematology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 28, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Improved Breast Cancer Survival Following Introduction of an Organized Mammography Screening Program Among Both Screened and Unscreened Women: a Population-Based Cohort StudyEmail this article to a colleague.
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This study investigated whether mammography screening is associated with optimized treatment and improved survival through multidisciplinary medical care. Breast Cancer Research (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 28, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Utility of CD56 Immunohistochemical Studies in Follow-up of Plasma Cell MyelomaEmail this article to a colleague.
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What is the potential role of CD56 immunohistochemical analysis in monitoring residual plasma cell myeloma? American Journal of Clinical Pathology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 25, 2009 Category: Cancer & Oncology Tags: Pathology & Lab Medicine Source Type: info
Can a Cocktail of F-18-Fluoride and F-18-FDG PET-CT Scan Be Useful in Imaging for Malignancy?Email this article to a colleague.
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Commentary on a pilot human study on the potential diagnostic utility of the combined administration of F-18-fluoride and F-18-FDG in a single PET-CT study for the detection of malignant lesions. Medscape Radiology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 25, 2009 Category: Cancer & Oncology Tags: Radiology Source Type: info
Tumour Aromatase Expression as a Prognostic Factor for Local Control in Young Breast Cancer Patients After Breast-Conserving TreatmentEmail this article to a colleague.
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Is there an association between expression levels of 17 candidate genes and locoregional control post breast-conserving treatment in young women with early-stage breast cancers? Breast Cancer Research (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 24, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Biological Determinants of Endocrine Resistance in Breast CancerEmail this article to a colleague.
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This article looks at current knowledge about the genetic lesions and molecular processes that determine endocrine resistance in breast cancer and how this may be used to improve therapy. Nature Reviews Cancer (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 24, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Endoscopic Therapy of Barrett's EsophagusEmail this article to a colleague.
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This article summarizes the different indications for endoscopic treatment of and the recent data on the different endoscopic treatment techniques for early neoplasia arising in Barrett's esophagus. Current Opinion in Gastroenterology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 22, 2009 Category: Cancer & Oncology Tags: Gastroenterology Source Type: info
Aspirin Use Reduces the Risk for Colorectal CancerEmail this article to a colleague.
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Even after its use was discontinued, aspirin offered protection against colon cancer in individuals with Lynch syndrome. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 22, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Changes in Screening, Prognosis and Therapy for Esophageal Adenocarcinoma in Barrett's EsophagusEmail this article to a colleague.
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This study reviews the important changes in concepts of managing Barrett's esophagus with regard to screening, surveillance, biomarkers, and therapies over the past several years. Current Opinion in Gastroenterology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 21, 2009 Category: Cancer & Oncology Tags: Gastroenterology Source Type: info
Genomic Profiling of Breast Tumours in Relation to BRCA Abnormalities and PhenotypesEmail this article to a colleague.
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Investigators assessed germline mutations in the BRCA1 and BRCA2 genes and looked for the involvement of these genes in breast tumor development. Breast Cancer Research (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 17, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Updates in Cancer Research: Insights From the AACR 100th Annual MeetingEmail this article to a colleague.
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Pivotal presentations from the AACR 100th Annual Meeting 2009 are reviewed, with discussion of scientific findings and their effect on clinical practices and ongoing clinical trials. Expert Review of Molecular Diagnostics (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 16, 2009 Category: Cancer & Oncology Tags: Pathology & Lab Medicine Source Type: info
Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer: F1000 Ranking "Changes Clinical Practice"Email this article to a colleague.
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The EGFR mutation is now testable on a large scale and treatable with gefitinib in patients with lung cancer. Faculty of 1000 Medicine (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 15, 2009 Category: Cancer & Oncology Tags: Internal Medicine Source Type: info
Combination Therapy With Transarterial Chemoembolization and Interferon-alpha Compared With Transarterial Chemoembolization Alone for Hepatitis B Virus Related Unresectable Hepatocellular CarcinomaEmail this article to a colleague.
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This study examined whether IFN-alpha treatment would reduce or postpone the recurrence rate and improve the overall survival rate in patients after TACE treatment of HBV-related unresectable HCC. (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 14, 2009 Category: Cancer & Oncology Tags: Gastroenterology Source Type: info
How Should a Nonfunctioning Pituitary Macroadenoma Be Monitored After Debulking Surgery?Email this article to a colleague.
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In view of the generally slow-growing nature of these tumors, yearly MRI, neuro-ophthalmologic- and pituitary-function evaluation are appropriate during the first 3–5 years after surgery. Clinical Endocrinology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 10, 2009 Category: Cancer & Oncology Tags: Diabetes & Endocrinology Source Type: info
Prevention of Hepatocellular Carcinoma in Hepatitis B Virus InfectionEmail this article to a colleague.
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This article assesses HBV vaccination program strategies in Asia in preventing chronic HBV infection and hepatocellular carcinoma and review strategies in controlling liver disease in chronic HBV. Journal of Gastroenterology and Hepatology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 10, 2009 Category: Cancer & Oncology Tags: Gastroenterology Source Type: info
Treatment of Head and Neck Cancers: Issues for Clinical PharmacistsEmail this article to a colleague.
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Read this clinical update to learn more about how to optimize therapy for patients by balancing efficacy and toxicity. Pharmacotherapy (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 10, 2009 Category: Cancer & Oncology Tags: Pharmacist Source Type: info
Post-Traumatic Stress Disorder Related to the Cancer ExperienceEmail this article to a colleague.
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PTSD may be surprisingly prevalent and severe in cancer patients, and may persist among survivors long after primary treatment ends. Oncology Nursing Forum (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 9, 2009 Category: Cancer & Oncology Tags: Nursing Source Type: info
The Impact of Dry Versus Moist Heat on Peripheral IV Catheter Insertion in a Hematology-Oncology Outpatient PopulationEmail this article to a colleague.
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Does moisture matter for easing IV insertion? Oncology Nursing Forum (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 8, 2009 Category: Cancer & Oncology Tags: Nursing Source Type: info
Putting Evidence Into Practice: Evidence-Based Interventions to Prevent, Manage, and Treat Chemotherapy- and Radiotherapy-Induced DiarrheaEmail this article to a colleague.
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The effects of treatment-induced diarrhea can range from disruptive to deadly, but evidence supports a variety of interventions--some quite simple. Clinical Journal of Oncology Nursing (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 8, 2009 Category: Cancer & Oncology Tags: Nursing Source Type: info
Epidemiology of Breast Cancer Subtypes in Two Prospective Cohort Studies of Breast Cancer SurvivorsEmail this article to a colleague.
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Investigators attempted to describe breast tumor subtypes by common breast cancer risk factors and to determine correlates of subtypes with data from two breast cancer studies within a large HMO. Breast Cancer Research (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 8, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
Immunohistochemical Characterization of Subtypes of Male Breast CarcinomaEmail this article to a colleague.
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This study aimed to classify the molecular subtypes of male breast cancers and to evaluate their association with clinicopathologic features and expression patterns of EGFR and NF-kappaB. Breast Cancer Research (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 4, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
A Constant Risk of Familial Breast Cancer? A Population-Based Family StudyEmail this article to a colleague.
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Investigators examined whether a similar pattern exists in breast cancer incidence in first-degree relatives of breast cancer patients. Breast Cancer Research (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 3, 2009 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: info
