Medscape Hiv-Aids Headlines
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12th European AIDS Conference/European AIDS Clinical Society (EACS)
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Read clinically focused news coverage of key developments from the meeting. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - November 11, 2009 Category: Infectious Diseases Source Type: info
Rising Rates of HIV Infection Among Young US Men Who Have Sex With Men
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This article offers suggestions for reducing the risky sexual behaviors of these young men. The Pediatric Infectious Disease Journal® (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - November 10, 2009 Category: Infectious Diseases Tags: Pediatrics Source Type: info
More Non-AIDS-Defining Malignancies Among HIV-Infected Patients
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HIV-infected patients have a higher-than-average incidence of non-AIDS-defining malignancies, according to a report in the October 1st Journal of Acquired Immune Deficiency Syndromes. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - November 9, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Risk Factors for Treatment-Limiting Toxicities in Patients Starting Nevirapine-Containing Antiretroviral Therapy
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A single lab test may be all it takes to identify patients who are more likely to have to stop nevirapine-containing ART because of toxicity. AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 28, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Prevalence of Unprotected Anal Intercourse Among HIV-Diagnosed MSM in the United States: A Meta-Analysis
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This meta-analysis moves beyond previous qualitative reviews to provide quantitative information on the population of men who engage in this risky practice AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 28, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
How High Should the CD4 Cells Go?
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A meta-analysis set out to define a single CD4 cell threshold that correlated with reduced risk for infection or death. AIDS Clinical Care (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 28, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Rapid Assessment of HIV Risk Behavior in Drug-Using Sex Workers in Three Cities in South Africa
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This study explored the HIV risks, and barriers to risk reduction, that lie at the intersection of drug use and commercial sex. AIDS and Behavior (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 28, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Early Mortality and Cause of Deaths in Patients Using HAART in Brazil and the United States
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What HIV-infected patients die from, and when they die, is different in Baltimore than in Rio de Janeiro -- but one aspect of care is unfortunately the same in both cities. AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 23, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Poverty, Sex and HIV
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The relative influence of economic, social, and behavioral factors on the spread of HIV in Africa is measurable, and perhaps unexpected. AIDS and Behavior (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 22, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
A 32-Year-Old Man With Decreased Vision, Uveitis, and Optic Disc Edema
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A 32-year-old man presents with decreased vision, uveitis, and optic disc edema. What is your diagnosis? Medscape Ophthalmology (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 21, 2009 Category: Infectious Diseases Tags: Ophthalmology Source Type: info
No Clinical Benefit Seen With IL-2-Induced CD4+ Cell Increase in HIV Patients
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New research confirms that interleukin-2 therapy increases CD4+ cell counts in patients with HIV infection, but the increase does not translate into reduced risks of opportunistic disease or death. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 16, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
U.S. FDA Panel Recommends Wider Use of Pfizer HIV Drug
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A U.S. Food and Drug Administration advisory panel on Thursday recommended Pfizer Inc's HIV drug Selzentry be approved for wider use in certain patients with the disease, despite concern from several panel members that they were underwhelmed by the data. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 9, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Adult Combination Antiretroviral Therapy in Sub-Saharan Africa: Lessons from Botswana and Future Challenges
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Despite limited resources, this region has achieved impressive results in some aspects of HIV treatment and has strategies in place for further improvement. HIV Therapy (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 1, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Little Evidence That Hepatitis C Virus Leads to a Higher Risk of Mortality in the Absence of Cirrhosis and Excess Alcohol Intake: The Swiss Hepatitis C Cohort Study
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This study evaluated the all-cause mortality of participants in the Swiss Hepatitis C Cohort compared with the Swiss general population. Journal of Viral Hepatitis (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 1, 2009 Category: Infectious Diseases Tags: Gastroenterology Source Type: info
Update on HIV Viral-Load Assays: New Technologies and Testing in Resource-Limited Settings
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Efforts to provide laboratory facilities where HIV viral load can be tested with the newest assays must be a priority in resource-limited settings. Future Virology (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 29, 2009 Category: Infectious Diseases Tags: Infectious Diseases Source Type: info
Changes in Cognition During Antiretroviral Therapy: Comparison of 2 Different Ranking Systems to Measure Antiretroviral Drug Efficacy on HIV-Associated Neurocognitive Disorders
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In order for HAART regimens to be effective against HIV-associated neurocognitive disorders, good CNS penetration is necessary--but is it sufficient? JAIDS: Journal of Acquired Immune Deficiency Syndromes (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 28, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Time for Tenofovir in First-line Treatment of HIV in Resource-Limited Settings?
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Experts believe that the advantages of a first-line TDF regimen outweigh the disadvantages. Learn more here. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 22, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Integrase Inhibitor Shows Promise in Treatment-Naïve Patients With Drug-Resistant HIV Strains
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The STARTMRK trial demonstrates sustained clinical benefit and fewer adverse effects with raltegravir than the gold standard HIV regimen containing efavirenz. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 22, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Tenofovir-Associated Renal and Bone Toxicity
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This study describes the clinical presentation and renal and bone abnormalities related to treatment with tenofovir, and recommends screening for tenofovir-related toxicity. HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 21, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Fluorescence Assay Developed to Screen for Anti-HIV Agents
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For the first time, researchers have developed a fluorescence assay to screen for potential inhibitors of HIV envelope-mediated membrane fusion, according to a presentation given on Monday at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 18, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Liver Involvement Common With Syphilis in HIV-Infected Patients
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In a new study, 76% of HIV-infected patients with syphilis had some degree of liver involvement, and in 20%, hepatitis was the presenting symptom of syphilis, according to findings presented Monday at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 18, 2009 Category: Infectious Diseases Tags: Infectious Diseases Source Type: info
An Algorithm to Optimize Viral Load Testing in HIV-Positive Patients With Suspected First-Line Antiretroviral Therapy Failure in Cambodia
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These researchers have developed an algorithm for assessing patients with suspected first-line ART failure, so that viral load testing can be targeted toward those who need it most. JAIDS: Journal of Acquired Immune Deficiency Syndromes (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 18, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Antiretroviral Therapy May Reverse HIV-Induced Lung Abnormalities
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Antiretroviral therapy does not adversely affect lung function in HIV-infected patients and may actually have a beneficial effect, according to study findings presented Monday at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 16, 2009 Category: Infectious Diseases Tags: Infectious Diseases Source Type: info
Foreskin Inflammation Is Associated With HIV and Herpes Simplex Virus Type-2 Infections in Rakai, Uganda
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Epidemiologic data and foreskin specimens from Ugandan circumcision trials point to whether HIV infection, HIV viral load, and HSV-2 infection are associated with foreskin inflammation. AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 16, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
An HIV Patient With Substance Abuse
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An initial drug regimen that is simple, well tolerated, and usually effective failed in this patient because of ongoing problems with drug abuse and inadequate social support. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 15, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Physicians Are Talking About: The Million Med March on Washington
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Medscape Physician Connect members from across the country prepare to march on Washington. Medscape Family Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 15, 2009 Category: Infectious Diseases Tags: Family Medicine/Primary Care Source Type: info
GB Virus C Genotype 2 Predominance in a Hepatitis C Virus/HIV Infected Population Associated With Reduced Liver Disease
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This study attempted to identify the GBV-C genotype in an HCV/HIV coinfected population and determine if the GBV-C genotype contributes to a reduction in HCV-related liver disease. Journal of Gastroenterology and Hepatology (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 14, 2009 Category: Infectious Diseases Tags: Gastroenterology Source Type: info
Nucleoside-Sparing Regimen May Improve HAART-Related Lipodystrophy
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Switching HIV-infected patients to a nucleoside reverse-transcriptase inhibitor (NRTI)-sparing regimen limits mitochondrial toxicity with no loss of antiviral efficacy, researchers report in the September 15th issue of Clinical Infectious Diseases. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 14, 2009 Category: Infectious Diseases Tags: Infectious Diseases Source Type: info
Trends in Mortality and Antibiotic Resistance Among HIV-Infected Patients With Invasive Pneumococcal Disease
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Has the HAART era brought a reduction in the burden of invasive pneumococcal disease? HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 11, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
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Read clinically focused news coverage of key developments from the meeting. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 11, 2009 Category: Infectious Diseases Source Type: info
Low Maternal Vitamin D Increases Risk of HIV Transmission to Offspring
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In HIV-infected pregnant women, low levels of vitamin D are linked with a higher risk of virus transmission during pregnancy or breastfeeding, and also with an increase in infant mortality. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 9, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
How Reliable Is an Undetectable Viral Load?
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These researchers have calculated the approximate reliability of undetectable viral loads according to cut-off points, and identified the most important factor predicting reliability. HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 4, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
New HIV Vaccine Target Identified
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An analysis of broadly neutralizing antibodies from an HIV-infected donor has identified a new target for HIV vaccines, according to a report in the September 3rd issue of Sciencexpress. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 4, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Clinicians Have Greater Ethical Concerns About the 2006 HIV Testing Guidelines Than Patients
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CDC guidelines calling for general rather than specific consent for HIV testing and optional rather than mandatory prevention counseling raise more concerns among physicians than patients. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 2, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Spread of Cryptococcus Gattii into Pacific Northwest Region of the United States
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Cryptococcus gattii, a basidiomycotic yeast acquired by inhalation, can result in pneumonia and dissemination of distant CNS tissues. This human and animal pathogen is currently localized to the Pacific Northwest. Emerging Infectious Diseases (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 31, 2009 Category: Infectious Diseases Tags: Infectious Diseases Source Type: info
Randomized, Double-Blind, Placebo-Matched, Multicenter Trial of Abacavir/Lamivudine or Tenofovir/Emtricitabine with Lopinavir/Ritonavir for Initial HIV Treatment
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Triple-combination HAART is a standard of care for initial treatment of HIV-1 infection; this large trial compared the two most commonly prescribed dual-nucleoside backbones of these regimens. AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 28, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Long-Term Follow-Up of Nevirapine-Treated Patients in a Single-Center Cohort
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This study reviewed the safety and efficacy of nevirapine-based therapy in patients at a single clinic who have initiated NVP-containing combined antiretroviral therapy since 1994. HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 27, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Incorporating the CDC Recommendations for Adolescent HIV Screening Into Practice
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The CDC recommends that all patients ages 13 through 64 years should be offered routine, opt-out, HIV screening without separate written consent or prevention counseling. How can nurse practitioners help facilitate screening in their adolescent patients? Journal for Nurse Practitioners (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 26, 2009 Category: Infectious Diseases Tags: Nursing Source Type: info
Suboptimal CD4 Recovery on Long-Term Suppressive Highly Active Antiretroviral Therapy Is Associated with Favorable Outcome
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Many HIV-positive patients with long-term viral suppression have suboptimal CD4 recovery but higher markers of immune maturation and activation—and low morbidity and mortality. HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 25, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Hepatitis C Virus Infections Among HIV-Infected Men Who Have Sex With Men: An Expanding Epidemic
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Dutch researchers delve into the prevalence and determinants of HCV-HIV coinfection in The Netherlands. AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 21, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Reductions in HIV Transmission Risk Behavior Following Diagnosis of Primary HIV Infection: A Cohort of High-Risk Men Who Have Sex With Men
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The particularly high infectivity of primary HIV infection makes even transient risk reduction particularly valuable. How effective is counseling in this situation? HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 18, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Evidence for Why TB Strikes Early in HIV Disease
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Tuberculosis precedes other opportunistic infections in persons with HIV infection; this preclinical study suggests a biologic mechanism for that susceptibility. Commentary by John G. Bartlett, MD. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 18, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Tenofovir Disoproxil Fumarate in Pregnancy and Prevention of Mother-to-Child Transmission of HIV-1: Is it Time to Move on from Zidovudine?
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Although zidovudine remains the cornerstone for preventing mother-to-child transmission of HIV-1, single-dose tenofovir disoproxil fumarate during delivery may offer an additional advantage. HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 14, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Metabolic disorders and cardiovascular consequences of HIV infection and antiretroviral therapy
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Can HIV and ART cause derangement of the metabolic pathway and increase the risk of cardiovascular disease? Expert Review of Clinical Pharmacology (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 13, 2009 Category: Infectious Diseases Tags: Pharmacist Source Type: info
Uptake of and Virological Response to Antiretroviral Therapy Among HIV-infected Former and Current Injecting Drug Users and Persons in an Opiate Substitution Treatment Programme: The Swiss HIV Cohort Study
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Uptake of ART and virological response to it differs between current injecting drug users and those who’ve kicked the habit. HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 12, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Implementation of 'See-and-Treat' Cervical Cancer Prevention Services Linked to HIV Care in Zambia
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The authors say this is among the first efforts within to undertake cervical cancer prevention as a component of HIV care. AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 12, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Bone Loss With Anti-HIV Agents Not Dependent on Regimen
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Independently of the regime employed, initiation of antiretroviral therapy causes a reduction in bone mineral density (BMD) in HIV-infected patients, researchers report in the August issue of the Journal of Acquired Immune Deficiency Syndromes. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 11, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Targeted Testing for Acute HIV Infection in North Carolina
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Acute HIV infection can be identified accurately using targeted testing, the authors of this study found. AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 10, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
CD4 Cell-Guided Scheduled Treatment Interruptions in HIV-infected Patients With Sustained Immunologic Response to HAART
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This study compares continuous HAART with a CD4 cell-driven scheduled treatment interruption strategy. AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 10, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
Changing Mortality Trends in HIV-Infected US Women: Report
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Over the last several years, mortality among HIV-infected US women has reached a plateau, researchers report. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - August 5, 2009 Category: Infectious Diseases Tags: HIV/AIDS Source Type: info
