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Menopausal hot flashes: how long do they really last?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 427DOI: 10.1097/gme.0b013e3181a1bf1dAuthors: Warren, Michelle P. MD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (43 K) Source Type: journals

Effective herbal treatment of vasomotor symptoms-are we any closer?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 428DOI: 10.1097/gme.0b013e31819774e4Authors: Kaunitz, Andrew M. MD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (52 K) Source Type: journals

The risks of androgen treatment in postmenopausal women remain controversial: a need for equitable comparisons.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 430DOI: 10.1097/gme.0b013e3181a057efAuthors: Pru, James K. PhD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (52 K) Source Type: journals

Hot flashes: a rose is a rose is a rose.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 432DOI: 10.1097/gme.0b013e3181a05dd1Authors: Santoro, Nanette F. MD 1; Dicken, Cary L. MD 2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (48 K) Source Type: journals

Searching for effective, nonhormonal treatments for vasomotor symptoms: is there a needle in the haystack?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 434DOI: 10.1097/gme.0b013e3181a5937bAuthors: Soares, Claudio N. MD, PhD, FRCPC
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (51 K) Source Type: journals

Tapering versus cold turkey: symptoms versus successful discontinuation of menopausal hormone therapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 436DOI: 10.1097/gme.0b013e3181a057dbAuthors: Suffoletto, Jo-Anne MD 1; Hess, Rachel MD, MSc 2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (51 K) Source Type: journals

The need for evidence-based medicine to be integrated into clinical practice: role of The North American Menopause Society.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 438DOI: 10.1097/gme.0b013e3181a23e51Authors: Pinkerton, JoAnn V. MD 1; Wild, Robert A. MD, PhD, MPH 2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (69 K) Source Type: journals

Longitudinal changes in sexual functioning as women transition through menopause: results from the Study of Women's Health Across the Nation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results showed that pain during sexual intercourse increased and sexual desire decreased over the transition, whereas masturbation increased during the early transition, but then declined in postmenopause. Adjusting for other factors, the menopausal transition was not independently associated with reports of the importance of sex, sexual arousal, frequency of sexual intercourse, emotional satisfaction with partner, or physical pleasure.Page: 442DOI: 10.1097/gme.0b013e3181948dd0Authors: Avis, Nancy E. PhD 1; Brockwell, Sarah PhD 2; Randolph, John F. Jr MD 3; Shen, Shunhua MS 2; Cain, Virginia S. PhD 4; Ory, Marcia PhD 5; Gr...
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (175 K) Source Type: journals

Duration of vasomotor symptoms in middle-aged women: a longitudinal study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We reanalyzed primary data from 438 women in a 13-year longitudinal cohort study to estimate the duration of vasomotor hot flushes. The average duration of vasomotor symptoms in this sample is more than 5 years, substantially longer than had been previously reported.Page: 453DOI: 10.1097/gme.0b013e31818d414eAuthors: Col, Nananda F. MD, MPH, MPP, FACP 1; Guthrie, Janet R. PhD 2; Politi, Mary PhD 3; Dennerstein, Lorraine MBBS, FRANZCP, PhD 2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (92 K) Source Type: journals

MF101, a selective estrogen receptor [beta] modulator for the treatment of menopausal hot flushes: a phase II clinical trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 458DOI: 10.1097/gme.0b013e31818e64ddAuthors: Grady, Deborah MD, MPH 1,2; Sawaya, George F. MD 1; Johnson, Karen C. MD, MPH 3; Koltun, William MD 4; Hess, Rachel MD 5; Vittinghoff, Eric PhD 1; Kristof, Margaret MS, RN 1; Tagliaferri, Mary MD, LAC 6; Cohen, Isaac OMD, LAC 6; Ensrud, Kristine E. MD, MPH 7,8
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (263 K) Source Type: journals

Mammary gland and endometrial effects of testosterone in combination with oral estradiol and progesterone.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The present study aimed to evaluate the effects of testosterone cotherapy on mammary gland and endometrial measures in a postmenopausal primate model. The results do not support the idea that testosterone antagonizes the effects of combined hormone therapy on breast proliferation or markers of estrogen-receptor activity and the short-term effects of testosterone cotherapy on the mammary gland and endometrium were minimal.Page: 466DOI: 10.1097/gme.0b013e318191747aAuthors: Wood, Charles E. DVM, PhD; Lees, Cynthia J. DVM, PhD; Cline, J. Mark DVM, PhD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (1.05 M) Source Type: journals

Efficacy of nonestrogenic hot flash therapies among women stratified by breast cancer history and tamoxifen use: a pooled analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A meta-analysis of available studies evaluated the use of nonestrogenic therapies for hot flashes in groups of participants with and without a history of breast cancer and in participants with and without the concurrent use of tamoxifen, supporting that these treatments affect hot flashes equally well in all of these participant groups.Page: 477DOI: 10.1097/gme.0b013e31818c91caAuthors: Bardia, Aditya MBBS, MPH 1; Novotny, Paul MS 2; Sloan, Jeff PhD 2; Barton, Deb PhD 3; Loprinzi, Charles MD 3
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (446 K) Source Type: journals

The Acupuncture on Hot Flushes Among Menopausal Women (ACUFLASH) study, a randomized controlled trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The use of acupuncture plus self-care can contribute to a clinically relevant reduction in hot flashes and increased health-related quality of life in postmenopausal women.Page: 484DOI: 10.1097/gme.0b013e31818c02adAuthors: Borud, Einar Kristian MD, MPH 1; Alraek, Terje PhD 1; White, Adrian MD, PhD 2; Fonnebo, Vinjar MD, MSc, PhD 1; Eggen, Anne Elise PhD 3; Hammar, Mats MD, PhD 4; Astrand, Lotta Lindh RN 4; Theodorsson, Elvar MD, PhD 4; Grimsgaard, Sameline MD, MPH, PhD 1,5
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (364 K) Source Type: journals

Discontinuing postmenopausal hormone therapy: an observational study of tapering versus quitting cold turkey: is there a difference in recurrence of menopausal symptoms?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 494DOI: 10.1097/gme.0b013e31818fbff5Authors: Haskell, Sally G. MD 1,2; Bean-Mayberry, Bevanne MD, MHS 3,4; Gordon, Kirsha MS 1,2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (94 K) Source Type: journals

Attitudes of obstetrician-gynecologists toward the evidence from the Women's Health Initiative hormone therapy trials remain generally skeptical.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A significant proportion of obstetrician-gynecologists remain skeptical of the evidence from the WHI trials and critical of the decision to end the trials.Page: 500DOI: 10.1097/gme.0b013e31818fc36eAuthors: Power, Michael L. PhD; Anderson, Britta L. BA; Schulkin, Jay PhD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (277 K) Source Type: journals

A prospective study of the association between endogenous hormones and depressive symptoms in postmenopausal women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this population-based study of postmenopausal women, a 2-year decline in estradiol levels and, to a lesser extent, a large increase in FSH levels were associated with an increased risk of depressive symptoms. By contrast, there was no significant association between absolute levels of estradiol, FSH, estrone, testosterone or SHBG, and depressive symptoms.Page: 509DOI: 10.1097/gme.0b013e31818d635fAuthors: Ryan, Joanne MSc 1,2,3; Burger, Henry G. MD 4; Szoeke, Cassandra MBBS, PhD 1; Lehert, Philippe PhD 5; Ancelin, Marie-Laure PhD 2,3; Henderson, Victor W. MD, MS 6; Dennerstein, Lorraine MBBS, PhD 1
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (183 K) Source Type: journals

Sex impacts the relation between body composition and physical function in older adults.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to identify sex-specific relationships between physical activity, fitness, body composition, and balance and gait in older adults. Results indicate that balance and gait are more strongly influenced by body composition (both adiposity and lean mass) in women than in men.Page: 518DOI: 10.1097/gme.0b013e31818c931fAuthors: Valentine, Rudy J. MS; Misic, Mark M. PhD; Rosengren, Karl S. PhD; Woods, Jeffrey A. PhD; Evans, Ellen M. PhD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (154 K) Source Type: journals

Cervical polyps in postmenopausal women: is there a difference in risk?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The presence of any abnormality in cervical polyps is lower in postmenopausal women compared with premenopausal women.Page: 524DOI: 10.1097/gme.0b013e3181927286Authors: Schnatz, Peter F. DO 1-6; Ricci, Stephanie MD 1,3,5; O'Sullivan, David M. PhD 7
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (145 K) Source Type: journals

Diminished vaginal HOXA13 expression in women with pelvic organ prolapse.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 529DOI: 10.1097/gme.0b013e31818fb0c2Authors: Connell, Kathleen A. MD 1; Guess, Marsha K. MD 1; Tate, Alison MD 1; Andikyan, Vaagn MD 1; Bercik, Richard MD 1; Taylor, Hugh S. MD 2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (305 K) Source Type: journals

Relationship between circulating tumor necrosis factor system and bone mass before and after estrogen plus progestogen therapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The present study aimed to investigate the relationship between circulating tumor necrosis factor system and bone mineral density before and after estrogen plus progestogen therapy. The results show that circulating tumor necrosis factor system may not be clinically useful for predicting bone mineral density and bone response after estrogen plus progestogen therapy.Page: 534DOI: 10.1097/gme.0b013e3181920c77Authors: Kim, Jung Gu MD, PhD 1,2; Ku, Seung-Yup MD, PhD 1,2; Kim, Hoon MD 1; Chun, Sung Wook MD 1; Suh, Chang Suk MD, PhD 1; Choi, Young Min MD, PhD 1,2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (93 K) Source Type: journals

Effect of isoflavone extracts from Glycine max on human endothelial cell damage and on nitric oxide production.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we determined that soy isoflavones significantly protect ECV304 cells against H2O2 damage and promote NO synthesizing. Thus, these isoflavones can potentially act as a NO promoter and as an antioxidant.Page: 539DOI: 10.1097/gme.0b013e31818d6349Authors: Paulo, Michele MSc 1; Salvador, Mirian Mendonca BSc 2; Filho, Mario dos Anjos Neto PhD 2; Montes, Marlise Bonetti Agostinho BSc 1; Franceschini, Silvio Antonio MD 3; Toloi, Maria Regina Torqueti PhD 1
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (545 K) Source Type: journals

Flaxseed combined with low-dose estrogen therapy preserves bone tissue in ovariectomized rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, the effects of 10% dietary flaxseed, low-dose estrogen therapy, or their combination on bone mineral density, biomechanical strength, and skeletal fatty acid composition in an ovariectomized rat model of postmenopausal osteoporosis were determined. Results show that flaxseed + low-dose estrogen therapy provides the greatest protection against ovariectomy-induced bone loss at the lumbar vertebraPage: 545DOI: 10.1097/gme.0b013e31818fc00aAuthors: Sacco, Sandra M. MSc 1; Jiang, Jessica M.Y. MSc 1; Reza-Lopez, Sandra MSc 1; Ma, David W.L. PhD 1,2; Thompson, Lilian U. PhD 1; Ward, Wendy E. PhD 1
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (258 K) Source Type: journals

Effects of menopause and hormone therapy on erythrocyte deformability.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The results of this study indicate that erythrocyte deformability may worsen with the decrease in estrogen levels due to the onset of menopause, while also suggesting that estrogen therapy and estrogen plus progestogen therapy may help it to recover.Page: 555DOI: 10.1097/gme.0b013e31818c9306Authors: Sakashita, Tomohisa MD; Nobuzane, Takahiro MD; Miyoshi, Hiroshi MD, PhD; Fujiwara, Hisaya MD, PhD; Kudo, Yoshiki MD, PhD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (98 K) Source Type: journals

Effect of microdose transdermal 17[beta]-estradiol compared with raloxifene in the prevention of bone loss in healthy postmenopausal women: a 2-year, randomized, double-blind trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study involved a multicenter, randomized, double-blind, active-controlled, noninferiority trial with 500 osteopenic postmenopausal women that compared transdermal microdose E2 (0.014 mg/day) versus oral raloxifene (60 mg/day), administered for 2 years. Microdose E2 was similarly effective as raloxifene in preventing bone loss at the lumbar spine (the primary efficacy endpoint). Both treatments were well tolerated, with no clinically significant effect on endometrium or breast density.Page: 559DOI: 10.1097/gme.0b013e31818ebfbaAuthors: Schaefers, Matthias MD 1; Muysers, Christoph MSc 1; Alexandersen, Peter MD 2; Christiansen, Claus MD 2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (311 K) Source Type: journals

Influence of a walking program on the metabolic risk profile of obese postmenopausal women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Moderate-intensity physical activity, such as brisk walking, is sufficient to reduce the metabolic risk profile of postmenopausal women characterized by the presence of one or several clinical features of metabolic syndrome, but without overt coronary heart disease.Page: 566DOI: 10.1097/gme.0b013e31818d4137Authors: Roussel, Michel MSc 1; Garnier, Sophie PhD 1; Lemoine, Sophie PhD 1; Gaubert, Isabelle MSc 2; Charbonnier, Laurie Dt 1; Auneau, Gerard PhD 1,2; Mauriege, Pascale PhD 1,3
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (193 K) Source Type: journals

Validation of self-reported history of hysterectomy and oophorectomy among women in an integrated group practice setting.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study shows that self-report is a valid data collection tool for hysterectomy history, but care should be taken in querying for and interpreting self-reported oophorectomy history for determining menopause status.Page: 576DOI: 10.1097/gme.0b013e31818ffe28Authors: Phipps, Amanda I. MPH 1; Buist, Diana S.M. PhD 2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (269 K) Source Type: journals

The estrogenic component of tibolone reduces adiposity in female aromatase knockout mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aromatase knockout mouse has confirmed the efficacy of tibolone as a hormone therapy to reduce adipose tissue accumulation after menopause and also shows that aromatization of tibolone is not required to elicit these estrogenic effects.Page: 582DOI: 10.1097/gme.0b013e31818fb20bAuthors: Van Sinderen, Michelle L. BS 1,2; Chin Boon, Wah PhD 1,2,3; Ederveen, Antwan G.H. PhD 4; Kloosterboer, Helenius J. PhD 4; Simpson, Evan R. PhD 1; Jones, Margaret E.E. PhD 1,2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (325 K) Source Type: journals

Osteoprotective effect of Phaseolus vulgaris L in ovariectomy-induced osteopenia in rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ten-week treatment with methanolic extract of Phaseolus vulgaris L. prevented estrogen deficiencyYinduced osteopenia in bilaterally ovariectomized rats. The treatment was associated with improvement in density, mechanical strength, and microarchitecture of the bone without affecting the uterine mass in ovariectomized rats.Page: 589DOI: 10.1097/gme.0b013e31818e64c4Authors: Shirke, Sarika S. PhD; Jadhav, Sanket R. MPharm; Jagtap, Aarti G. PhD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (1.644 M) Source Type: journals

Serum antimullerian hormone predicts ovarian reserve in a monkey model.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Findings indicate that the relationship between antimüllerian hormone and ovarian reserve in monkeys is nearly identical to that of women. This finding, along with the many other reproductive similarities between monkeys and women, makes this species a potentially useful model for studying the effect of hormonal fluctuations across the menopausal transition on disease processes later in life.Page: 597DOI: 10.1097/gme.0b013e3181906fb6Authors: Appt, Susan E. DVM 1; Clarkson, Thomas B. DVM 1; Chen, Haiying MD, PhD 2; Adams, Michael R. DVM 1; Christian, Patricia J. BS 3; Hoyer, Patricia B. PhD 3; Wilson, Mark E. PhD 4; Kaplan, Jay R. PhD 1
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (198 K) Source Type: journals

Yoga for menopausal symptoms: a systematic review.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Based on an assessment of all the clinical trials included in this review, the data are insufficient to confirm that yoga is an effective intervention for menopausal symptoms. Further rigorous randomized controlled trials are needed to investigate whether there are specific benefits of yoga for treating menopausal symptoms.Page: 602DOI: 10.1097/gme.0b013e31818ffe39Authors: Lee, Myeong Soo PhD 1,2; Kim, Jong-In OMD, PhD 1; Ha, Jeong Yong PhD 3; Boddy, Kate MA 2; Ernst, Edzard MD, PhD, FRCP, FRCPEd 2
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (656 K) Source Type: journals

Designing the ideal selective estrogen receptor modulator-an achievable goal?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 609DOI: 10.1097/gme.0b013e3181906fa3Authors: Taylor, Hugh S. MD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: Abstract HTML PDF (125 K) Source Type: journals

Is phytotherapy effective in menopausal dysphoric disorder?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 616DOI: 10.1097/gme.0b013e31819c15b1Authors: Niederhofer, Helmut MD, PhD, MAS
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (61 K) Source Type: journals

In response.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 616DOI: 10.1097/gme.0b013e31819b865eAuthors: van Die, Margaret Diana BA, Dip Herb Med, Dip Ed 1; Burger, Henry G. MD, FRACP 2; Bone, Kerry M. BSc, Dip Phyt, FNIMH, FNHAA 3; Teede, Helena J. MBBS, PhD, FRACP 4
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (61 K) Source Type: journals

Understanding female sexual function.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 425DOI: 10.1097/gme.0b013e31819c67a7Authors: Davis, Susan R. MBBS, FRACP, PhD
Source: Menopause - May 10, 2009 Category: OBGYN Tags: HTML PDF (48 K) Source Type: journals

The sexual health benefits of oral low-dose estrogen plus progestogen and vaginal estrogen for postmenopausal women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 224DOI: 10.1097/gme.0b013e31819748fdAuthors: Kingsberg, Sheryl A. PhD
Source: Menopause - March 7, 2009 Category: OBGYN Tags: HTML PDF (53 K) Source Type: journals

Androgens, estrogens, and metabolic syndrome at midlife.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 226DOI: 10.1097/gme.0b013e3181974ffcAuthors: Shifren, Jan L. MD
Source: Menopause - March 7, 2009 Category: OBGYN Tags: HTML PDF (61 K) Source Type: journals

Beyond the obvious: why behavioral interventions matter.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 229DOI: 10.1097/gme.0b013e31819b2e00Authors: Berga, Sarah L. MD
Source: Menopause - March 7, 2009 Category: OBGYN Tags: HTML PDF (46 K) Source Type: journals

Vasomotor symptoms are associated with a lower bone mineral density.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study vasomotor symptoms were associated with a reduced bone density. It could be hypothesized that women with vasomotor symptoms might be more susceptible to the beneficial effects of estrogens, possibly by neutralizing the effect of estrogen fluctuations.Page: 231DOI: 10.1097/gme.0b013e318185e25bAuthors: Gast, Gerrie-Cor M. MSc 1,2; Grobbee, Diederick E. MD, PhD 1; Pop, Victor J.M. MD, PhD 3; Keyzer, Jules J. PhD 4; Wijnands-van Gent, Colette J.M. MD, PhD 4; Samsioe, Goran N. MD, PhD 2; Nilsson, Peter M. MD, PhD 5; van der Schouw, Yvonne T. PhD 1
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (116 K) Source Type: journals

Presence of vasomotor symptoms is associated with lower bone mineral density: a longitudinal analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To determine the association between vasomotor symptoms and bone mineral density, data were analyzed from 2213 participants of the Study of Women's Health Across the Nation. Even in the earliest menopause transition stages, women with vasomotor symptoms had lower bone mineral density on average compared to women without vasomotor symptoms.Page: 239DOI: 10.1097/gme.0b013e3181857964Authors: Crandall, Carolyn J. MD, MS 1; Zheng, Yan MS 1; Crawford, Sybil L. PhD 2; Thurston, Rebecca C. PhD 3; Gold, Ellen B. PhD 4; Johnston, Janet M. PhD 5; Greendale, Gail A. MD 1
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (283 K) Source Type: journals

A randomized study of low-dose conjugated estrogens on sexual function and quality of life in postmenopausal women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study demonstrates the value of a regimen of vaginal conjugated estrogens and low dose oral hormone therapy to relieve dyspareunia in a large prospective, randomized, multinational study.Page: 247DOI: 10.1097/gme.0b013e318184c440Authors: Gast, Michael J. MD, PhD 1; Freedman, Murray A. MD 2; Vieweg, Alberta J. MPH 1; De Melo, Nilson R. MD 3; Girao, Manoel J.B.C. MD, PhD 4; Zinaman, Michael J. MD 5; the Dyspareunia Study Group
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (724 K) Source Type: journals

Relative androgen excess during the menopausal transition predicts incident metabolic syndrome in midlife women: Study of Women's Health Across the Nation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
With the onset of menopause, ovarian estradiol production declines dramatically, but the concomitant drop in sex hormone binding globulin and more modest drop in androgen production leads to an increase in the ratio of bioavailable testosterone to estradiol. In the Study of Women's Health Across the Nation, the magnitude of this ratio-called Relative Androgen Excess-is shown to be associated with incident cases of metabolic syndrome.Page: 257DOI: 10.1097/gme.0b013e318185e249Authors: Torrens, Javier I. MD 1; Sutton-Tyrrell, Kim PhD 2; Zhao, Xinhua PhD 2; Matthews, Karen PhD 2; Brockwell, Sarah PhD 2; Sowers, MaryFran PhD 3;...
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (179 K) Source Type: journals

Physical activity, menopause, and quality of life: the role of affect and self-worth across time.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A two-year follow-up survey was conducted with middle-aged women previously enrolled in a randomized controlled exercise trial to examine the relationship between physical activity and menopause-related quality of life (QOL). The results indicated that increasing physical activity over time may enhance QOL, albeit indirectly via its effects on physical self-worth and positive affect.Page: 265DOI: 10.1097/gme.0b013e31818c0284Authors: Elavsky, Steriani PhD
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (199 K) Source Type: journals

Pharmacokinetics of dehydroepiandrosterone and its metabolites after long-term oral dehydroepiandrosterone treatment in postmenopausal women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In postmenopausal women treated orally with a commonly available dose of dehydroepiandrosterone (DHEA), the daily exposure (AUC) of DHEA and its principal androgenic and estrogenic metabolites was found to be similar during 6 months of treatment, despite elevated serum baseline concentrations of these hormones.Page: 272DOI: 10.1097/gme.0b013e31818adb3fAuthors: Stanczyk, Frank Z. PhD 1,2; Slater, Cristin C. MD 1; Ramos, Diana E. MD 1; Azen, Colleen MS 3; Cherala, Ganesh PhD 4,5; Hakala, Charles RPh 6; Abraham, Guy MD 7; Roy, Subir MD 1
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (117 K) Source Type: journals

Hysterectomy and weight gain.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study explores whether overweight women are more likely to have a hysterectomy and whether hysterectomy leads to increased weight gain. The findings indicate the among women aged above 45-50 years, hysterectomy does not lead to greater weight gain, but is more likely to be performed in heavier women.Page: 279DOI: 10.1097/gme.0b013e3181865373Authors: Fitzgerald, David M. BSc; Berecki-Gisolf, Janneke MD, PhD; Hockey, Richard L. BSc, DipAgrSc; Dobson, Annette J. PhD
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (102 K) Source Type: journals

Frequency and severity of hot flashes and sleep disturbance in postmenopausal women with hot flashes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study concurrently assessed self-reported hot flashes, insomnia symptoms, and objective parameters of sleep-wake patterns in a cohort of 217 healthy postmenopausal women aged 40-60 years with hot flashes. The frequency and severity of hot flashes was independently associated in a graded manner with severity of insomnia symptoms and objective measures of disrupted sleep including nighttime wakefulness and sleep fragmentation.Page: 286DOI: 10.1097/gme.0b013e31818c0485Authors: Ensrud, Kristine E. MD, MPH 1,2,3; Stone, Katie L. PhD 4; Blackwell, Terri L. MA 4; Sawaya, George F. MD 5,6; Tagliaferri, Mary MD 7; Diem, Susan ...
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (98 K) Source Type: journals

Tamoxifen use and endometrial lesions: hysteroscopic, histological, and immunohistochemical findings in postmenopausal women with breast cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study all cases of endometrial polyps were ER positive. Estrogen receptors may play a major role in the development of endometrial polyps in postmenopausal women taking tamoxifen.Page: 293DOI: 10.1097/gme.0b013e31818af10aAuthors: Dibi, Raquel P. MD 1,2; Zettler, Claudio G. MD, PhD 2,3; Pessini, Suzana A. MD 1; Ayub, Alice V. MD 1; de Almeida, Suzane B. MD 1; da Silveira, Gustavo P.G. MD, PhD 1,2
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (844 K) Source Type: journals

Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 2-year randomized, double-blind, placebo-controlled study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In postmenopausal women, the phytoestrogen genisein is effective on vasomotor symptoms compared to placebo after two years of treatment. It was well-tolerated and had no side effects on the endometrium.Page: 301DOI: 10.1097/gme.0b013e318186d7e2Authors: D'Anna, Rosario MD 1; Cannata, Maria Letizia MD 1; Marini, Herbert MD 2; Atteritano, Marco MD 3; Cancellieri, Francesco MD 1; Corrado, Francesco MD 1; Triolo, Onofrio MD 1; Rizzo, Piero MD 1; Russo, Silvia MD 1; Gaudio, Agostino MD 3; Frisina, Nicola MD 3; Bitto, Alessandra MD 4; Polito, Francesca PhD 4; Minutoli, Letteria MD 4; Altavilla, Domenica PhD 4; Adamo, Elena Bianca...
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (568 K) Source Type: journals

Effects of Hypericum perforatum (St. John's wort) on hot flashes and quality of life in perimenopausal women: a randomized pilot trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This pilot, double-blind, randomized clinical trial suggests that Hypericum perforatum extract may improve symptoms and quality of life in ways that are important to symptomatic menopausal women compared to placebo.Page: 307DOI: 10.1097/gme.0b013e31818572a0Authors: Al-Akoum, Mahera MD, MSc 1; Maunsell, Elizabeth PhD 2,3,4; Verreault, Rene MD, PhD 3; Provencher, Louise MD, FRCSc 2,3,4; Otis, Helene MD 4; Dodin, Sylvie MD, MSc 1
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (263 K) Source Type: journals

Nonhormonal drug use and its relation to androgens in perimenopausal women: a population-based study of Swedish women. The Women's Health in the Lund Area Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This is a population-based study on perimenopausal women, illustrating the prevalence of non-hormonal medication usage among the different groups of this sample. Androgens seem to be as important as other sex-hormones for general health in postmenopausal women.Page: 315DOI: 10.1097/gme.0b013e31818c0456Authors: Khatibi, Ali MD, PhD 1; Agardh, Carl-David MD, PhD 2; Lidfeldt, Jonas MD, PhD 2; Samsioe, Goran MD, PhD 1
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (89 K) Source Type: journals

Effects of soy protein isolate on bone mineral density and physical performance indices in postmenopausal women-a 2-year randomized, double-blind, placebo-controlled trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study the effect of 25 g of soy protein isolate with 90 mg of isoflavones on BMD and physical performance was examined in a cohort of elderly postmenopausal women. The findings suggest that soy with or without isoflavones has no significant effect on either BMD or physical performance measures in these women compared to milk-based protein placebo.Page: 320DOI: 10.1097/gme.0b013e3181844893Authors: Vupadhyayula, Phani M. MD 1; Gallagher, J. C. MD 1; Templin, Thomas MS 1; Logsdon, Susannah M. MS 1; Smith, Lynette M. MS 2
Source: Menopause - March 7, 2009 Category: OBGYN Tags: Abstract HTML PDF (180 K) Source Type: journals