Effects of Mediterranean diet on semen parameters in healthy young adults: a randomized controlled trial.
CONCLUSIONS: In healthy young adults, the consumption of Mediterranean diet was associated with an improvement of both sperm concentration and total count, as compared with a low-fat diet.
PMID: 33478205 [PubMed - in process] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - January 24, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Polycystic ovary syndrome, amenorrhea and the diagnostic role of anti-M üllerian hormone.
Polycystic ovary syndrome, amenorrhea and the diagnostic role of anti-Müllerian hormone.
Minerva Endocrinol. 2020 Dec;45(4):376-380
Authors: Capuzzo M, Donno V, LA Marca A
Abstract
The differential diagnosis of anovulatory disorders is actually based on serum gonadotrophin and estradiol levels. However, several other markers have been proposed. The purpose of this review was to underline the role of anti-Müllerian hormone (AMH) as a possible marker in differential diagnosis of the anovulatory diseases and its use as a predictive marker of prognosis. In this article we discuss cl...
Source: Minerva Endocrinologica - January 24, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
The level of the neudesin in Type-2 Diabetic patients and the relationship between the metabolic parameters and carotid intima-media thickness.
CONCLUSIONS: Serum neudesin increased in new diagnosis Type-2 DM patients. This increase seems to be related to obesity and insulin resistance. However, more extensive research is needed to clarify this issue.
PMID: 33435641 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Clinical management of low-risk papillary thyroid microcarcinoma.
Authors: Masaki C, Sugino K, Ito K
Abstract
Papillary thyroid microcarcinoma (PTMC) is well known to have an indolent nature with an excellent prognosis. Surgery has been the standard treatment during the past several decades, with metastasis or recurrence being exceedingly rare. Active surveillance (AS) is a new risk-adapted approach alternative to surgery that involves just watching, but not giving any treatment unless needed, not addressing the tumor itself. The patients for whom AS is adopted spend their time "with tumors". In follow-up, it is possible that alarming factors such as tumor progression ap...
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Pubertal induction in girls with Turner syndrome.
Authors: Aversa T, Corica D, Pepe G, Pajno GB, Valenzise M, Messina MF, Wasniewska M
Abstract
Turner syndrome (TS) is the most common female sex chromosome aneuploidy in females, and patients may present with hypergonadotropic hypogonadism due to gonadal dysgenesis. Timing and modalities of pubertal induction in these patients is still a matter of debate. Aim of this review is to focus on the latest update on pubertal induction in TS. Based on literature data, the following practical approach to this issue is recommended. Pubertal induction should begin between 11 and 12 years of age, starting with low dos...
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Endocrine dysfunction and cognitive impairment.
Authors: Calsolaro V, Bottari M, Coppini G, Lemmi B, Monzani F
Abstract
Dementia is a highly prevalent chronic disease among the older population, affecting more than 50 million people worldwide and representing a huge healthcare, social and economic burden. Dementia, and in particular Alzheimer's disease, prevalence is expected to raise within the next few years. Unfortunately, no disease-modifying therapies are available so far, despite a plethora of clinical trials targeting the hallmarks of Alzheimer's disease. Given these premises, it appears crucial to address not only the neuropathological correlate...
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Ethnic differences in the impact of gestational diabetes on macrosomia.
CONCLUSIONS: GDM is an independent predictor of macrosomia in Latin-American, South-Central Asian and Moroccan women but not in Caucasian or East-Asian women in whom other factors play a more important role.
PMID: 33435645 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Normal thyroid volume in subjects evaluated in a primary ambulatory setting in Liguria.
CONCLUSIONS: Reference values of TV in the Ligurian population are now available. TV in the general population could be compared with these normative data.
PMID: 33435646 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
A retrospective comparison between intensive and non-intensive insulin regimens in type 2 diabetes mellitus.
CONCLUSIONS: Both intensive and non-intensive insulin therapies improved the baseline glycemic parameters, but being overweight or obese and/or being reluctant to dietary recommendations led to treatment failures regardless of the insulin regimen.
PMID: 33435647 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Does Abelmoschus Esculentus act as anti-diabetic? A systematic review with updated evidence.
CONCLUSIONS: This review can highlight the current evidence of the particular topic, useful for a reader to gain knowledge, application in clinical practice in a community setting, or planning for new human experiment in depth.
PMID: 33435648 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Clinicopathological significance of epidermal growth factor receptor expression in papillary thyroid carcinoma: a meta-analysis.
CONCLUSIONS: The results in the expression of EGFR is frequent and cancer-specific event in PTC. Besides, the expression of EGFR was involved in the progression and metastasis of PTC.
PMID: 33435649 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Obesity and COVID-19: 2 The ominous duet affecting the renin-angiotensin system.
Authors: Luzi L, Bucciarelli L, Ferrulli A, Terruzzi I, Massarini S
Abstract
The World population is facing a health challenge never seen since the Spanish influenza of one hundred years ago. During the last months, the scientific community has been debating on the potential harmful effect of Angiotensin-converting-enzyme inhibitors (ACEi) or Angiotensin II receptor Type 1 receptor blockers (AT1-Receptor blockers, ARBs) during the COVID-19 pandemic. That is because the S spike protein of SARS8 CoV viruses utilizes the angiotensin-converting enzyme 2 (ACE2) as a receptor to enter alveolar epithelial cells. ...
Source: Minerva Endocrinologica - January 15, 2021 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
The endocrinology of sarcopenia and frailty.
CONCLUSIONS: A life-course approach to improving 'health-span' is advocated. Lifestyle factors such as nutrition and physical activity have important interactions with body composition, physical function and metabolic outcomes. Large-scale clinical trials will determine the efficacy and long-term safety of hormone supplementation in the management of sarcopenia and frailty.
PMID: 33331737 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - December 19, 2020 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
New risk factors in diabetic nephropathy: microRNA-196-3p and microRNA-203.
CONCLUSIONS: Increased serum levels of miR-203 and miR-196a-3p are independent risk factors of UAE which is a marker of DN.
PMID: 33331738 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - December 19, 2020 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Recent advances in small cell lung cancer: the future is now?
Authors: Luciani A, Blasi M, Provenzano L, Zonato S, Ferrari D
Abstract
Small cell lung cancer is a relevant clinical issue as it is a highly malignant cancer, often diagnosed in advanced stage. Similarly to non-small cell lung cancer, tobacco smoking is currently the main risk factor. Its incidence, at least in males, has declined over the past decades, due to the worldwide decreased percentage of active smokers. The typical small cells of this tumor type are characterized by a high proliferation index, chromosomal deletions such as 3p(14-23) involving the tumor-suppressor gene FHIT, alterations of the MY...
Source: Minerva Endocrinologica - December 19, 2020 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
