C3HeB/FeJ Mice mimic many aspects of gene expression and pathobiological features of human hepatocellular carcinoma
Hepatocellular carcinoma (HCC) remains a deadly cancer, underscoring the need for relevant preclinical models. Male C3HeB/FeJ mice model spontaneous HCC with some hepatocarcinogenesis susceptibility loci corresponding to syntenic regions of human chromosomes altered in HCC. We tested other properties of C3HeB/FeJ tumors for similarity to human HCC. C3HeB/FeJ tumors were grossly visible at 4 months of age, with prevalence and size increasing until about 11 months of age. Histologic features shared with human HCC include hepatosteatosis, tumor progression from dysplasia to poorly differentiated, vascular invasion, and trabec...
Source: Molecular Carcinogenesis - November 25, 2018 Category: Molecular Biology Authors: Jessica A. Zavadil,
Maryanne C. S. Herzig,
Kim Hildreth,
Amir Foroushani,
William Boswell,
Ronald Walter,
Robert Reddick,
Hugh White,
Habil Zare,
Christi A. Walter Tags: RESEARCH ARTICLE Source Type: research
Lymphotoxin ‐β receptor‐NIK signaling induces alternative RELB/NF‐κB2 activation to promote metastatic gene expression and cell migration in head and neck cancer
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - November 22, 2018 Category: Molecular Biology Authors: Rita Das,
Jamie Coupar,
Paul E. Clavijo,
Anthony Saleh,
Tsu ‐Fan Cheng,
Xinping Yang,
Jianhong Chen,
Carter VanWaes,
Zhong Chen Tags: RESEARCH ARTICLE Source Type: research
Genetic polymorphisms of diabetes ‐related genes, their interaction with diabetes status, and breast cancer incidence and mortality: The Long Island Breast Cancer Study Project
Conclusions: Genetic polymorphisms that increase the risk of developing diabetes may also increase the risk of developing and dying from BC. This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - November 20, 2018 Category: Molecular Biology Authors: Humberto Parada,
Rebecca J. Cleveland,
Kari E. North,
June Stevens,
Susan L. Teitelbaum,
Alfred I. Neugut,
Regina M. Santella,
Maria Elena Martinez,
Marilie D. Gammon Tags: RESEARCH ARTICLE Source Type: research
DSCAM ‐AS1 promotes tumor growth of breast cancer by reducing miR‐204‐5p and up‐regulating RRM2
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - November 20, 2018 Category: Molecular Biology Authors: Wen ‐Hui Liang,
Na Li,
Zhi‐Qing Yuan,
Xin‐Lai Qian,
Zhi‐Hui Wang Tags: RESEARCH ARTICLE Source Type: research
PPP3CB contributes to poor prognosis through activating nuclear factor of activated T ‐cells signaling in neuroblastoma
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - November 20, 2018 Category: Molecular Biology Authors: Irina Shakhova,
Yuanyuan Li,
Fan Yu,
Yoshiki Kaneko,
Yohko Nakamura,
Miki Ohira,
Hideki Izumi,
Takao Mae,
Svetlana R. Varfolomeeva,
Alexander G. Rumyantsev,
Akira Nakagawara Tags: RESEARCH ARTICLE Source Type: research
NRP ‐1 INTERACTS WITH GIPC1 and SYX TO ACTIVATE p38 MAPK SIGNALING AND CANCER STEM CELL SURVIVAL
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - November 19, 2018 Category: Molecular Biology Authors: Daniel Grun,
Gautam Adhikary,
Richard L. Eckert Tags: RESEARCH ARTICLE Source Type: research
HMGB1 ‐RAGE signaling facilitates Ras‐dependent Yap1 expression to drive colorectal cancer stemness and development
This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - November 19, 2018 Category: Molecular Biology Authors: Qian fei,
Jianjia Xiao,
Ling Gai,
Jianwei Zhu Tags: RESEARCH ARTICLE Source Type: research
Issue Information ‐ Ed Board
Molecular Carcinogenesis,Volume 57, Issue 12, Page 1673-1673, December 2018. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - November 3, 2018 Category: Molecular Biology Source Type: research
Wnt signaling dynamics in head and neck squamous cell cancer tumor ‐stroma interactions
Molecular Carcinogenesis,Volume 0, Issue ja, -Not available-. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - October 31, 2018 Category: Molecular Biology Authors: Phuong N. Le,
Stephen B. Keysar,
Bettina Miller,
Justin R. Eagles,
Tugs ‐Saikhan Chimed,
Julie Reisinger,
Karina E. Gomez,
Cera Nieto,
Brian C. Jackson,
Hilary L. Somerset,
J. Jason Morton,
Xiao‐Jing Wang,
Antonio Jimeno Source Type: research
Cytoglobin ameliorates the stemness of hepatocellular carcinoma via coupling oxidative ‐nitrosative stress signals
Molecular Carcinogenesis,Volume 0, Issue ja, -Not available-. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - October 26, 2018 Category: Molecular Biology Authors: Jun Zhang,
YuanYuan Pei,
Wen Yang,
WenXiu Yang,
Boxin Chen,
Xing Zhao,
Shiqi Long Source Type: research
Hyaluronan ‐CD44/RHAMM interaction‐dependent cell proliferation and survival in lung cancer cells
Molecular Carcinogenesis,Volume 0, Issue ja, -Not available-. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - October 26, 2018 Category: Molecular Biology Authors: Jung Min Song,
Jintaek Im,
Richard Seonghun Nho,
Yong Hwan Han,
Pramod Upadhyaya,
Fekadu Kassie Source Type: research
C3HeB/FeJ MiceMimic many aspects of Gene Expression and Pathobiological Features of Human Hepatocellular Carcinoma
Molecular Carcinogenesis,Volume 0, Issue ja, -Not available-. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - October 26, 2018 Category: Molecular Biology Authors: Jessica A. Zavadil,
Maryanne C.S. Herzig,
Kim Hildreth,
Amir Foroushani,
William Boswell,
Ronald Walter,
Robert Reddick,
Hugh White,
Habil Zare,
Christi A. Walter Source Type: research
Extracellular vesicle secretion of miR ‐142‐3p from lung adenocarcinoma cells induces tumor promoting changes in the stroma through cell‐cell communication
Molecular Carcinogenesis,Volume 0, Issue ja, -Not available-. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - October 26, 2018 Category: Molecular Biology Authors: James Lawson,
Christopher Dickman,
Rebecca Towle,
James Jabalee,
Ariana Rani,
Cathie Garnis Source Type: research
Tumor suppressive activity of PIWI ‐interacting RNA in human fibrosarcoma mediated through repression of RRM2
Molecular Carcinogenesis,Volume 0, Issue ja, -Not available-. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - October 26, 2018 Category: Molecular Biology Authors: Basudeb Das,
Jyoti Roy,
Neha Jain,
Bibekanand Mallick Source Type: research
lncRNA DRHC inhibits proliferation and invasion in hepatocellular carcinoma via c ‐Myb‐regulated MEK/ERK signaling
Molecular Carcinogenesis,Volume 0, Issue ja, -Not available-. (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - October 26, 2018 Category: Molecular Biology Authors: Runzhou Zhuang,
Xuanyu Zhang,
Di Lu,
Jianguo Wang,
Jianyong Zhuo,
Xuyong Wei,
Qi Ling,
Haiyang Xie,
Shusen Zheng,
Xiao Xu Source Type: research
