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From the editorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 831 (2009). doi:10.1038/nrn2772 The fortieth annual Society for Neuroscience meeting this year welcomed over 30,000 delegates and was again a resounding success, with talks and posters pointing to important developments and approaches in neuroscience, several of which will feature in forthcoming issues of Nature Reviews Neuroscience.MicroRNAs (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 20, 2009 Category: Neuroscience Tags: From The Editors Source Type: journals

In BriefEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 835 (2009). doi:10.1038/nrn2771 Place cells (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 20, 2009 Category: Neuroscience Tags: Research Highlight Source Type: journals

In BriefEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 834 (2009). doi:10.1038/nrn2770 Pain (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 20, 2009 Category: Neuroscience Tags: Research Highlight Source Type: journals

Development: Initiation of a new connectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 833 (2009). doi:10.1038/nrn2769 Author: Claudia Wiedemann The molecular mechanisms that regulate synapse formation are not well understood. Eroglu et al. show that thrombospondin (TSP) binding to the neuronal α2δ-1 receptor initiates the formation of new synapses in vitro and in vivo and that the anti-epileptic and analgesic drug (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 20, 2009 Category: Neuroscience Authors: Claudia Wiedemann Tags: Research Highlight Source Type: journals

Epigenetics: Stressed for lifeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 836 (2009). doi:10.1038/nrn2768 Author: Leonie Welberg Early-life stress (ELS) has long-lasting effects on the brain, and the epigenetic mechanisms underlying them are beginning to be unravelled. Murgatroyd et al. now show that methyl-CpG-binding protein 2 (MeCP2)-mediated regulation of arginine vasopressin (Avp) gene expression in parvocellular hypothalamus (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 20, 2009 Category: Neuroscience Authors: Leonie Welberg Tags: Research Highlight Source Type: journals

Neurogenesis: A mother–daughter relationshipEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Neurogenesis: A mother–daughter relationship Nature Reviews Neuroscience 10, 833 (2009). doi:10.1038/nrn2767 Author: Katherine Whalley Radial glia in the ventricular zone (VZ) of the developing cortex divide asymmetrically, producing a self-renewing radial glial cell that remains in the VZ and a cell that differentiates into a neuron or an intermediate progenitor. How these differing fates are determined was unknown; however, (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 20, 2009 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: journals

Neural coding: Oscillations help to decode spike patternsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 834 (2009). doi:10.1038/nrn2766 Author: Monica Hoyos Flight In sensory processing, a neuron's firing rate and the timing of the spikes relative to the stimulus onset together encode information. In reality, however, stimuli are often ongoing, raising the question of what else could provide a reference point for spike timing. Previous studies suggested (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 20, 2009 Category: Neuroscience Authors: Monica Hoyos Flight Tags: Research Highlight Source Type: journals

TrkB signalling pathways in LTP and learningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 850 (2009). doi:10.1038/nrn2738 Author: Liliana Minichiello Understanding the mechanisms that underlie learning is one of the most fascinating and central aims of neurobiological research. Hippocampal long-term potentiation (LTP) is widely regarded as a prime candidate for the cellular mechanism of learning. The receptor tyrosine kinase TrkB (also known as NTRK2), known (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 20, 2009 Category: Neuroscience Authors: Liliana Minichiello Tags: Review Source Type: journals

Neuroimmunology: Crawling into the brainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 834 (2009). doi:10.1038/nrn2765 Author: Lucy Bird A study involving real-time imaging of effector T cells provides new insight into how autoreactive T cells interact with cerebral structures and access the central nervous system (CNS) to cause autoimmune disease.Flügel and colleagues induced experimental autoimmune encephalomyelitis in rats with intravenous injection of (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 11, 2009 Category: Neuroscience Authors: Lucy Bird Tags: Research Highlight Source Type: journals

Learning and memory: Dopamine drives the circuitEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 832 (2009). doi:10.1038/nrn2764 Author: Leonie Welberg Flies rely on their sense of smell to navigate their environment. Mushroom body neurons have a key role in olfactory memory, but little is known about the circuits that provide these cells with relevant information. Two studies now identify distinct dopaminergic projections to specific mushroom (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 11, 2009 Category: Neuroscience Authors: Leonie Welberg Tags: Research Highlight Source Type: journals

Neurodegenerative disease: APP: what's on the inside mattersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 836 (2009). doi:10.1038/nrn2760 Author: Katherine Whalley Cleavage of the amyloid precursor protein (APP) at the cell surface produces extracellular amyloid-β peptides (Aβ) and the APP intracellular domain, AICD. The predominant hypotheses in the Alzheimer's disease (AD) field have traditionally focused on a causative role for Aβ; however, a new (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 11, 2009 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: journals

Plasticity and stability of visual field maps in adult primary visual cortexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
rnakis It is important to understand the balance between cortical plasticity and stability in various systems and across spatial scales in the adult brain. Here we review studies of adult plasticity in primary visual cortex (V1), which has a key role in distributing visual information. There (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 11, 2009 Category: Neuroscience Authors: Brian A. WandellStelios M. Smirnakis Tags: Review Source Type: journals

Understanding microRNAs in neurodegenerationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
. Dawson Interest in the functions of microRNAs (miRNAs) in the nervous system has recently expanded to include their roles in neurodegeneration. Investigations have begun to reveal the influence of miRNAs on both neuronal survival and the accumulation of toxic proteins that are associated with neurodegeneration, and (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 11, 2009 Category: Neuroscience Authors: Stephen M. EackerTed M. DawsonValina L. Dawson Tags: Progress Source Type: journals

A new perspective on the role of the orbitofrontal cortex in adaptive behaviourEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Takahashi The orbitofrontal cortex (OFC) is crucial for changing established behaviour in the face of unexpected outcomes. This function has been attributed to the role of the OFC in response inhibition or to the idea that the OFC is a rapidly flexible associative-learning area. However, recent (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 11, 2009 Category: Neuroscience Authors: Geoffrey SchoenbaumMatthew R. RoeschThomas A. StalnakerYuji K. Takahashi Tags: Perspectives Source Type: journals

Plasticity during stroke recovery: from synapse to behaviourEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
orbett Reductions in blood flow to the brain of sufficient duration and extent lead to stroke, which results in damage to neuronal networks and the impairment of sensation, movement or cognition. Evidence from animal models suggests that a time-limited window of neuroplasticity opens following a stroke, (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 4, 2009 Category: Neuroscience Authors: Timothy H. MurphyDale Corbett Tags: Review Source Type: journals

microRNAs at the synapseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 842 (2009). doi:10.1038/nrn2763 Author: Gerhard Schratt MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene regulation in a plethora of tissues, including the nervous system. Recent evidence points to a widespread role for neural miRNAs at various stages of synaptic development, including dendritogenesis, synapse formation and synapse maturation. Furthermore, studies (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - November 4, 2009 Category: Neuroscience Authors: Gerhard Schratt Tags: Review Source Type: journals

In BriefEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 767 (2009). doi:10.1038/nrn2752 Oscillations (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Tags: Research Highlight Source Type: journals

In BriefEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 764 (2009). doi:10.1038/nrn2751 Neurodegenerative disease (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Tags: Research Highlight Source Type: journals

From the editorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 761 (2009). doi:10.1038/nrn2750 As this month's issue goes to press we eagerly anticipate this year's Society for Neuroscience meeting in Chicago, which as always promises to bring together scientists from all fields of neuroscience. The meeting often leads to an interest in topics that might not be directly (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Tags: From The Editors Source Type: journals

Affective disorders: Antidepressant action through gene regulationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 765 (2009). doi:10.1038/nrn2749 Author: Charlotte Harrison A recent paper in the Journal of Neuroscience has shown that inhibitors of histone deacetylases (HDACs) — enzymes that affect the acetylation status of histones and regulate the remodelling of chromatin — have antidepressant actions.Although currently used antidepressants rapidly modulate monoaminergic systems in (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Authors: Charlotte Harrison Tags: Research Highlight Source Type: journals

The origin and evolution of synapsesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 829 (2009). doi:10.1038/nrn2748 Author: Tomás J. Ryan & Seth G. N. Grant Nature Reviews Neuroscience10, 701–712 (2009)On page 708 of the above article, the word 'deuterostomes' was incorrectly used instead of 'protostomes'. The sentence should have read: “Protostomes have single NR2 and Dlg genes whereas chordates have four (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Authors: Tomás J. RyanSeth G. N. Grant Tags: Corrigendum Source Type: journals

Development: Scaling with microRNAsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 766 (2009). doi:10.1038/nrn2747 Author: Claudia Wiedemann Once dendrites have established coverage of their receptive fields during development, growth of the dendritic arbour in synchrony with body growth (dendritic scaling) is essential to maintain the coverage. How this proportional growth of dendrites is coordinated is largely unknown. A study by Jan and (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Authors: Claudia Wiedemann Tags: Research Highlight Source Type: journals

Psychiatric disorders: DISC1 drives development through girdinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 763 (2009). doi:10.1038/nrn2746 Author: Katherine Whalley Mutations in disrupted in schizophrenia 1 (DISC1) are a risk factor for multiple psychiatric and mental disorders, and DISC1 regulates diverse aspects of neuronal physiology. However, the molecular mechanisms by which DISC1 mediates its effects are largely unknown. Enomoto et al. and (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: journals

Synaptic plasticity: Astrocytes as regulatorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 766 (2009). doi:10.1038/nrn2745 Author: Katherine Whalley That astrocytes are more than merely supportive elements of the nervous system is no longer news: in recent years they have been linked to multiple processes, including the regulation of synapse formation and neuronal activity. Filosa et al. now show that neuron–astrocyte interactions that (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: journals

NeurocultureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anker Neuroscience addresses questions that, if resolved, will reveal aspects of our individuality. Therefore neuroscientific knowledge is not solely constrained within laboratories, but readily captures the attention of the public at large. Ideas, concepts and images in neuroscience widely circulate in culture and are portrayed in (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 20, 2009 Category: Neuroscience Authors: Giovanni FrazzettoSuzanne Anker Tags: Perspectives Source Type: journals

The functional anatomy of the frontal lobesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
d Husain In their illuminating recent article (Is the rostro-caudal axis of the frontal lobe hierarchical? Nature Rev. Neurosci.10, 659–669 (2009)), Badre and D'Esposito generalize to the frontal lobes as a whole a point we recently made about (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 13, 2009 Category: Neuroscience Authors: Parashkev NachevChristopher KennardMasud Husain Tags: Correspondence Source Type: journals

Zinc in the physiology and pathology of the CNSEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ael Sekler The past few years have witnessed dramatic progress on all frontiers of zinc neurobiology. The recent development of powerful tools, including zinc-sensitive fluorescent probes, selective chelators and genetically modified animal models, has brought a deeper understanding of the roles of this cation as a crucial (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 13, 2009 Category: Neuroscience Authors: Stefano L. SensiPierre PaolettiAshley I. BushIsrael Sekler Tags: Review Source Type: journals

Neurological disorders: Connectivity in RettEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 765 (2009). doi:10.1038/nrn2744 Author: Claudia Wiedemann Rett syndrome is a neurodevelopmental disorder that manifests in early childhood and is caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MECP2). Previous studies have shown that synaptic input to layer 5 pyramidal neurons is abnormal in Mecp2-null mice, (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 13, 2009 Category: Neuroscience Authors: Claudia Wiedemann Tags: Research Highlight Source Type: journals

Neuroimaging: Learning changes the resting brainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 766 (2009). doi:10.1038/nrn2743 Author: Leonie Welberg The resting brain is not idle but shows continuous, spontaneous fluctuations in activity, which correlate between functionally related brain regions. Previous studies indicated that spontaneous, resting-state functional connectivity remains stable during development, sleep and anaesthesia, but Corbetta and colleagues now show that it can change (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 13, 2009 Category: Neuroscience Authors: Leonie Welberg Tags: Research Highlight Source Type: journals

The Allen Brain Atlas: 5 years and beyondEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
. Sunkin The Allen Brain Atlas, a Web-based, genome-wide atlas of gene expression in the adult mouse brain, was an experiment on a massive scale. The development of the atlas faced a combination of great technical challenges and a non-traditional open research model, and it encountered many (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 13, 2009 Category: Neuroscience Authors: Allan R. JonesCaroline C. OverlySusan M. Sunkin Tags: Perspectives Source Type: journals

Neurodegenerative disease: Sleeping away amyloid plaques?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 764 (2009). doi:10.1038/nrn2742 Author: Leonie Welberg Aggregation of extracellular amyloid-β (Aβ) is thought to play a major part in the pathogenesis of Alzheimer's disease. Amyloid plaques form when levels of the monomeric, soluble Aβ peptide build up in the interstitial fluid (ISF) in the brain. Holtzman and colleagues now show that (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 13, 2009 Category: Neuroscience Authors: Leonie Welberg Tags: Research Highlight Source Type: journals

What does the retrosplenial cortex do?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Maguire The past decade has seen a transformation in research on the retrosplenial cortex (RSC). This cortical area has emerged as a key member of a core network of brain regions that underpins a range of cognitive functions, including episodic memory, navigation, imagination and planning for (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 7, 2009 Category: Neuroscience Authors: Seralynne D. VannJohn P. AggletonEleanor A. Maguire Tags: Review Source Type: journals

REM sleep and dreaming: towards a theory of protoconsciousnessEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 803 (2009). doi:10.1038/nrn2716 Author: J. Allan Hobson Dreaming has fascinated and mystified humankind for ages: the bizarre and evanescent qualities of dreams have invited boundless speculation about their origin, meaning and purpose. For most of the twentieth century, scientific dream theories were mainly psychological. Since the discovery of rapid eye movement (REM) (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 30, 2009 Category: Neuroscience Authors: J. Allan Hobson Tags: Review Source Type: journals

From the editorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 693 (2009). doi:10.1038/nrn2732 Our special focus issue this month celebrates the contribution of Darwin's ideas to our understanding of the evolution of the nervous system, featuring articles that discuss the molecular, cellular and structural changes that have contributed to CNS evolution and the functional consequences of these changes. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Tags: From The Editors Source Type: journals

In BriefEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 697 (2009). doi:10.1038/nrn2731 Synaptic plasticity (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Tags: Research Highlight Source Type: journals

Neurodegenerative disease: Proving the linkEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 694 (2009). doi:10.1038/nrn2730 Author: Katherine Whalley Some prion diseases have been associated with familial mutations in the gene encoding the prion protein (PrP). However, how these mutations contribute to the disease process was not well understood. Lindquist and colleagues now show for the first time that mutations in PrP can produce (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: journals

Fear: Extracellular barriersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 698 (2009). doi:10.1038/nrn2729 Author: Claudia Wiedemann The regulation of fear memory extinction differs between juvenile and adult mice; however, the molecular basis of this difference is not known. Herry and colleagues now show that the formation of perineuronal nets (PNNs) in the amygdala prevents the permanent extinction of fear memories in (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Authors: Claudia Wiedemann Tags: Research Highlight Source Type: journals

Circadian rhythms: Timing with miRNAsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 696 (2009). doi:10.1038/nrn2728 Author: Claudia Wiedemann Circadian rhythms such as the locomotor activity rhythm are regulated by changes in gene transcription; however, little is known about the role of post-transcriptional mechanisms. Kadener et al. identify candidate microRNAs (miRNAs) that influence circadian rhythmicity and show that in Drosophila melanogaster the (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Authors: Claudia Wiedemann Tags: Research Highlight Source Type: journals

In BriefEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 696 (2009). doi:10.1038/nrn2727 Social neuroscience (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Tags: Research Highlight Source Type: journals

Evolution of the neocortex: a perspective from developmental biologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article describes how novelties that make us (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Authors: Pasko Rakic Tags: Review Source Type: journals

Synaptic remodelling: Sculpting the NMJEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 698 (2009). doi:10.1038/nrn2718 Author: Katherine Whalley During neuromuscular junction (NMJ) development, target muscle cells become innervated by the axonal arbor of one motor neuron. As the muscle grows, the arbor size increases and new synapses are added. Fuentes-Medel et al. have now examined this process in the Drosophila melanogaster (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: journals

Considering the evolution of regeneration in the central nervous systemEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
rretti For many years the mammalian CNS has been seen as an organ that is unable to regenerate. However, it was also long known that lower vertebrate species are capable of impressive regeneration of CNS structures. How did this situation arise through evolution? Increasing cellular and (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 24, 2009 Category: Neuroscience Authors: Elly M. TanakaPatrizia Ferretti Tags: Review Source Type: journals

Modes and regulation of glial migration in vertebrates and invertebratesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 769 (2009). doi:10.1038/nrn2720 Author: Christian Klämbt Neurons and glial cells show mutual interdependence in many developmental and functional aspects of their biology. To establish their intricate relationships with neurons, glial cells must migrate over what are often long distances. In the CNS glial cells generally migrate as single cells, whereas PNS (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 22, 2009 Category: Neuroscience Authors: Christian Klämbt Tags: Review Source Type: journals

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Nature Reviews Neuroscience 10, 625 (2009). doi:10.1038/nrn2715 Neuroimmunology (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 22, 2009 Category: Neuroscience Tags: Research Highlight Source Type: journals

In BriefEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 622 (2009). doi:10.1038/nrn2714 Ion channelsv (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 22, 2009 Category: Neuroscience Tags: Research Highlight Source Type: journals

From the editorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 619 (2009). doi:10.1038/nrn2712 Repairing damage to the nervous system that occurs as a result of trauma or disease remains one of the key goals of neuroscience research. Several of the strategies under investigation are highlighted in this month's issue. Approaches that are being considered to protect and repair (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 22, 2009 Category: Neuroscience Tags: From The Editors Source Type: journals

Axon guidance: Sorting themselves outEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 624 (2009). doi:10.1038/nrn2711 Author: Katherine Whalley How do the topographic maps that are characteristic of sensory brain regions form during development? Sakano and colleagues show that interactions between neuropilin 1 (NRP1) and its ligand semaphorin 3A (SEMA3A) regulate the organization of olfactory sensory neuron (OSN) axons long before they reach their (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 22, 2009 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: journals

Repair: CSI in SCIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 621 (2009). doi:10.1038/nrn2710 Author: Claudia Wiedemann The success of current approaches to promote recovery of motor function after spinal cord injury (SCI) is often very limited. Three studies using rodents now describe several potential new treatment strategies for SCI.The role of infiltrating macrophages and resident microglia in the recovery from (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 22, 2009 Category: Neuroscience Authors: Claudia Wiedemann Tags: Research Highlight Source Type: journals

Neurodegenerative disease: Avoiding bad complement in Alzheimer's diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 623 (2009). doi:10.1038/nrn2709 Author: Monica Hoyos Flight Despite evidence of an involvement of inflammatory and immunological mechanisms in the pathogenesis of Alzheimer's disease, the therapeutic benefits of anti-inflammatory agents are still unclear. A study published in the Journal of Immunology shows for the first time that inhibition of the receptor for (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 22, 2009 Category: Neuroscience Authors: Monica Hoyos Flight Tags: Research Highlight Source Type: journals

Reward: Dopamine's expanding universeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 624 (2009). doi:10.1038/nrn2708 Author: Leonie Welberg Dopamine has a well-established role in learning and decision making related to rewarding stimuli that are important for survival, such as food, water and sex. Two papers now extend dopamine's functional repertoire to include roles in processing abstract rewards and in perceptual decision making.Bromberg-Martin (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - September 22, 2009 Category: Neuroscience Authors: Leonie Welberg Tags: Research Highlight Source Type: journals