NeLM - Disease Focused ReviewsThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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6 records returned

Meta-analysis: beta-blocker dose, heart rate reduction, and death in patients with heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This review concluded that the magnitude of heart rate reduction was statistically significantly associated with the survival benefit of beta-blockers in heart failure, but the dose of beta-blocker was not. The majority of the review process and the synthesis were well conducted. Despite the absence of a validity assessment, the conclusions appear likely to be reliable. [Included studies assessed metoprolol, carvedilol, bisoprolol, bucindolol, nebivolol and atenolol. ] CRD Commentary: The review question was clear and was supported by specific inclusio...
Source: NeLM - Disease Focused Reviews - November 6, 2009 Category: Internal Medicine Source Type: organizations

Treatment of pressure ulcers:a systematic reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This review, which evaluated therapies for pressure ulcers, concluded there was little evidence favouring any particular support surface or dressing, nor evidence favouring other treatments compared to standard care. The authors' conclusions are likely to be reliable. CRD Commentary: The review addressed a clear question and was supported by appropriate inclusion criteria. A number of electronic databases were searched and, although a search was made for studies published not in English, the authors did not report searching for unpublished studies, so so...
Source: NeLM - Disease Focused Reviews - October 20, 2009 Category: Internal Medicine Source Type: organizations

Cannabinoids for Tourette's SyndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Cochrane Library Area: Evidence > Disease Focused Reviews Background Gilles de la Tourette Syndrome (GTS) is a developmental neuropsychiatric disorder characterised by the presence of chronic motor and phonic tics. Drugs currently used in the treatment of GTS either lack efficacy or are associated with intolerable side effects. There is some anecdotal and experimental evidence that cannabinoids may be effective in treating tics and compulsive behaviour in patients with GTS. There are currently no systematic Cochrane reviews of treatments used in GTS. There is one other Cochrane review being undertaken at presen...
Source: NeLM - Disease Focused Reviews - October 18, 2009 Category: Internal Medicine Source Type: organizations

Antimicrobial central venous catheters in adults: a systematic review and meta-analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This review assessed the efficacy of antimicrobial central venous catheters in adults, concluding that chlorhexidine-silver sulfadiazine or minocycline-rifampicin central venous catheters can be considered when the baseline incidence of catheter-related bloodstream infections is above institutional goals. The authors' conclusions reflect the limitations of the evidence and are likely to be reliable. CRD Commentary: This review addressed a clear question and undertook a thorough search for studies with no language restrictions. No evidence of publication ...
Source: NeLM - Disease Focused Reviews - October 8, 2009 Category: Internal Medicine Source Type: organizations

Comparative benefits and harms of competing medications for adults with attention-deficit hyperactivity disorder: a systematic review and indirect comparison meta-analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This generally well-conducted review assessed the efficacy and safety of treatments for attention-deficit hyperactivity disorder in adults. The authors concluded that the use of immediate release methylphenidate as a first-line treatment was supported. The questionable quality of many of the included studies and some concerns over the appropriateness of the synthesis may mean these conclusions were overstated. [Studies of the following treatments were eligible: amphetamine mixture, dextroamphetamine sulphate, methylphenidate HCl, dexmethylphenidate HCl, ...
Source: NeLM - Disease Focused Reviews - September 14, 2009 Category: Internal Medicine Source Type: organizations

Infection-control interventions for cancer patients after chemotherapy: a systematic review and meta-analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This review concluded that protective isolation interventions including administration of prophylactic antibiotics reduced mortality in cancer patients or stem cell transplant recipients at high risk of infection. Outpatient management of stem cell transplant recipients reduced mortality in observational studies and should be evaluated in randomised trials. The authors' conclusions reflected the evidence presented and appeared likely to be reliable. CRD Commentary: This review had clear inclusion criteria. The search covered a number of relevant...
Source: NeLM - Disease Focused Reviews - August 23, 2009 Category: Internal Medicine Source Type: organizations