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PRaCTICaL study finds no benefit from nurse led, intensive care follow-up programmes for improving long term outcomes from critical illnessemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: BMJ Area: News Critically ill patients who require intensive care have severe and prolonged physical and psychological morbidity, and excess mortality, in the years after discharge from intensive care. Follow-up programmes have been developed to improve the quality of life of these patients. A pragmatic, non-blinded, RCT was conducted to ascertain if nurse led follow-up programmes are effective and cost effective in improving quality of life after discharge from intensive care.   The study conducted at three UK hospitals (two teaching hospitals and one district general hospital) involved 286 patients aged...
Source: NeLM - Intensive Care (ICU) - October 19, 2009 Category: Intensive Care Source Type: organizations

Link between initial vancomycin concentration-time profile and nephrotoxicity in hospitalised patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Clin Infect Dis Area: News This retrospective study aimed to determine which of two pharmacodynamic parameters (area under the curve [AUC] or trough value) best described the relationship between vancomycin exposure and onset of nephrotoxicity.   The study involved 166 patients in receipt of vancomycin for a suspected or proven gram positive infection at a US medical centre hospital from January 2005 to December 2006 who fulfilled the following criteria:   1. 18 years of age or older 2. absolute neutrophil count of 1000 cells/mm3 or higher 3. on vancomycin for > 48 h 4.&nbs...
Source: NeLM - Intensive Care (ICU) - August 20, 2009 Category: Intensive Care Source Type: organizations

Review: IV therapy for hypertensive emergencies (part 2)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Am J Health-Syst Pharm Area: News In the second part of this article published in the American Journal of Health-System Pharmacy on IV antihypertensive agents for the treatment of hypertensive emergencies, the clinical evidence of efficacy and safety of these agents in the following settings are reviewed:   . Hypertensive emergencies. . Ischaemic stroke . Haemorrhagic stroke . Perioperative hypertension . Acute aortic dissection . Preeclampsia and eclampsia . Acute coronary syndromes . Acute pulmonary embolism   The first article covered the rationale for I...
Source: NeLM - Intensive Care (ICU) - August 13, 2009 Category: Intensive Care Source Type: organizations

Metoclopramide for migration of naso-enteral tubeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Cochrane Library Area: Evidence > Drug Specific Reviews Background Enteral alimentation by feeding tube is a common and efficient method of providing nutritional support to hospitalized patients with insufficient oral intake, but adequate gastrointestinal function. The use of metoclopramide, a prokinetic agent, has been recommended to achieve transpyloric placement, but its efficacy is controversial. Objectives To determine the effect of intravenous metoclopramide on transpyloric passage of the naso-enteral tube. Search strategy Trials were identified by searching MEDLINE 1996 to November 2008, EMBASE 1988...
Source: NeLM - Intensive Care (ICU) - August 5, 2009 Category: Intensive Care Source Type: organizations

Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Cochrane Library Area: Evidence > Disease Focused Reviews Background Post-extubation stridor may prolong length of stay in the intensive care unit, particularly if airway obstruction is severe and re-intubation proves necessary. Some clinicians use corticosteroids to prevent or treat post-extubation stridor, but corticosteroids may be associated with adverse effects ranging from hypertension to hyperglycaemia, so a systematic assessment of the efficacy of this therapy is indicated. Objectives To determine whether corticosteroids are effective in preventing or treating post-extubation stridor in critically ill...
Source: NeLM - Intensive Care (ICU) - July 27, 2009 Category: Intensive Care Source Type: organizations