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Is Routine TORCH Screening Warranted in Neonates with Lenticulostriate Vasculopathy?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Routinely applied efforts to diagnose congenital infections in cases presenting with LSV have a poor yield. Routine TORCH screening in neonates with LSV cases should only be regarded as mandatory once well-designed studies demonstrate a clear diagnostic benefit. PMID: 19887856 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - November 4, 2009 Category: Perinatology & Neonatology Authors: de Jong EP, Lopriore E, Vossen AC, Steggerda SJ, Te Pas AB, Kroes AC, Walther FJ Tags: Neonatology Source Type: journals

Neurally Adjusted Ventilatory Assist and Pressure Support Ventilation in Small Species and the Impact of Instrumental Dead Space.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: This study demonstrates, in a small group of animals, that NAVA can deliver assist in very small species with a higher efficiency than PSV in terms of eliminating CO(2) for a given minute ventilation. PMID: 19887857 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - November 4, 2009 Category: Perinatology & Neonatology Authors: Campoccia Jalde F, Almadhoob AR, Beck J, Slutsky AS, Dunn MS, Sinderby C Tags: Neonatology Source Type: journals

N-Carbamylglutamate in Emergency Management of Hyperammonemia in Neonatal Acute Onset Propionic and Methylmalonic Aciduria.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on two full-term neonates, one with propionic aciduria and the other with methylmalonic aciduria, whose plasma ammonia concentrations responded dramatically to oral N-carbamylglutamate. N-carbamylglutamate, added to the classic treatment, quickly normalized plasma ammonia levels in both patients and avoided the need of hemodialysis or peritoneal dialysis. A particularly sudden fall of ammonia was obtained in one patient through beginning N-carbamylglutamate treatment precociously. PMID: 19887858 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - November 4, 2009 Category: Perinatology & Neonatology Authors: Filippi L, Gozzini E, Fiorini P, Malvagia S, la Marca G, Donati MA Tags: Neonatology Source Type: journals

Low Leptin Concentration in the First Gestational Trimester Is Associated with Being Born Small for Gestational Age: Prospective Study in Rio de Janeiro, Brazil.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Lower leptin concentrations were associated with a significant risk for SGA after adjusting for confounding variables. Maternal serum leptin at the beginning of gestation can be used as a marker for the early detection of SGA. PMID: 19887859 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - November 4, 2009 Category: Perinatology & Neonatology Authors: Franco-Sena AB, Goldani MZ, Tavares do Carmo MD, Velásquez-Melendez G, Kac G Tags: Neonatology Source Type: journals

High Faecal Calprotectin Levels in Healthy, Exclusively Breast-Fed Infants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our findings show that the kind of feeding influences the faecal calprotectin concentration, with higher values in healthy exclusively BF infants than in FF ones. Our study does not allow us to clearly identify the reason for our finding; this could be due to hormones (such as ghrelin and leptin), cytokines and other immunostimulating and growth factors (such as epidermal growth factor and granulocyte colony-stimulating factor) in human milk, which contribute to the development of the gastrointestinal immune system. Further investigations are needed to better clarify the mechanism underlying the relationship b...
Source: Neonatology - November 4, 2009 Category: Perinatology & Neonatology Authors: Savino F, Castagno E, Calabrese R, Viola S, Oggero R, Miniero R Tags: Neonatology Source Type: journals

Cord Blood Cardiac Troponin T and Nonprotein-Bound Iron Levels in Newborns of Mild Pre-Eclamptic Mothers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Increased levels of cTnT may be a biochemical marker of cardiac involvement in babies of mild pre-eclamptic mothers. In this study, no correlation was found between cTnT levels and NPBI levels. PMID: 19887861 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - November 4, 2009 Category: Perinatology & Neonatology Authors: Karadeniz L, Coban A, Ince Z, Turkoglu U, Can G Tags: Neonatology Source Type: journals

Impact of Skin to Skin Care, Prone and Supine Positioning on Cardiorespiratory Parameters and Thermoregulation in Premature Infants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: We found no significant SSC-mediated changes in quality and quantity of desaturations and in body temperature compared to PP in preterm infants. PMID: 19887862 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - November 4, 2009 Category: Perinatology & Neonatology Authors: Heimann K, Vaeβen P, Peschgens T, Stanzel S, Wenzl TG, Orlikowsky T Tags: Neonatology Source Type: journals

Skin to Skin Care in the Neonatal Intensive Care Unit: More Data Regarding Seriously Ill Infants Are Badly Needed. Commentary on Heimann et al.: Impact of Skin to Skin Care, Prone and Supine Positioning on Cardiorespiratory Parameters and Thermoregulation in Premature Infants (Neonatology 2010;97:311-317).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19887863 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - November 4, 2009 Category: Perinatology & Neonatology Authors: Bohnhorst B Tags: Neonatology Source Type: journals

Anatomy of the Circle of Willis and Blood Flow in the Brain-Feeding Vasculature in Prematurely Born Infants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Preterm neonates show a high prevalence of variant types of the circle of Willis at term-equivalent age. A relation could be demonstrated between variations in the circle of Willis and the flow in the ICA and BA. PMID: 19887852 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 30, 2009 Category: Perinatology & Neonatology Authors: van Kooij BJ, Hendrikse J, Benders MJ, de Vries LS, Groenendaal F Tags: Neonatology Source Type: journals

Closure Times Measured by the Platelet Function Analyzer PFA-100(R) Are Longer in Neonatal Blood Compared to Cord Blood Samples.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Platelet function in response to ADP appears to improve with advancing GA. The differences between cord blood and neonatal blood CTs indicate that substantial changes in primary hemostasis occur shortly after birth. The reasons underlying these changes are unknown. PMID: 19887853 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 30, 2009 Category: Perinatology & Neonatology Authors: Saxonhouse MA, Garner R, Mammel L, Li Q, Muller KE, Greywoode J, Miller C, Sola-Visner M Tags: Neonatology Source Type: journals

Maternal-to-Infant Transmission of Probiotics: Concept Validation in Mice, Rats, and Pigs.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Probiotic bacteria administered to mothers during late gestation are transferred to infants born vaginally and influence the assemblages of GIT bacteria. However, colonization of the neonatal GIT and persistence past weaning does not occur in all offspring and varies among probiotics and animal models. PMID: 19887854 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 30, 2009 Category: Perinatology & Neonatology Authors: Buddington RK, Williams CH, Kostek BM, Buddington KK, Kullen MJ Tags: Neonatology Source Type: journals

Glucocorticoids Suppress Growth in Neonatal Cardiomyocytes Co-Expressing AT(2) and AT(1) Angiotensin Receptors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The present study provides novel evidence that glucocorticoids suppress neonatal cardiomyocyte growth responsiveness when AT(2 )and AT(1) receptor subtypes are co-expressed. PMID: 19887855 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 30, 2009 Category: Perinatology & Neonatology Authors: Porrello ER, Meeker WF, Thomas WG, Widdop RE, Delbridge LM Tags: Neonatology Source Type: journals

Effect of Posture on Brain Hemodynamics in Preterm Newborns Not Mechanically Ventilated.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Hemodynamic changes after posture variations depend on GA. Head rotation in newborns with GA </=26 weeks produced a reduction in nTHI with stable TOI. Possible physiopathological mechanisms are discussed. PMID: 19887848 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 29, 2009 Category: Perinatology & Neonatology Authors: Ancora G, Maranella E, Aceti A, Pierantoni L, Grandi S, Corvaglia L, Faldella G Tags: Neonatology Source Type: journals

Overfeeding Can Cause NEC-Like Enterocolitis in Premature Rat Pups.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Increased expression of IkappaB-alpha/beta suggested that the inflammatory mediator nuclear factor-kappaB is deeply involved in the pathogenesis of enterocolitis that can be easily introduced by overfeeding of milk ingestion in premature rat pups which mimic those seen in NEC. Increased expression of PPAR-gamma may possibly regulate further development of enterocolitis in this system. PMID: 19887849 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 29, 2009 Category: Perinatology & Neonatology Authors: Okada K, Fujii T, Ohtsuka Y, Yamakawa Y, Izumi H, Yamashiro Y, Shimizu T Tags: Neonatology Source Type: journals

Is Screening for Renal Anomalies Warranted in Neonates with Isolated Single Umbilical Artery?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The prevalence of renal anomalies in neonates with isolated SUA is low. We suggest that routine ultrasound screening for renal anomalies is not warranted in neonates with isolated SUA. PMID: 19887850 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 29, 2009 Category: Perinatology & Neonatology Authors: de Boom ML, Kist-van Holthe JE, Sramek A, Lardenoye SW, Walther FJ, Lopriore E Tags: Neonatology Source Type: journals

Clara Cell Secretory Protein in Tracheobronchial Aspirates and Umbilical Cord Serum of Extremely Premature Infants with Systemic Inflammation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Reduced anti-inflammatory CC10 concentrations in airways of extremely premature infants with a fetal inflammatory response might make their lungs susceptible for further postnatal injuries. Umbilical cord serum CC10 is not an indicator for a fetal systemic inflammatory reaction. PMID: 19887851 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 29, 2009 Category: Perinatology & Neonatology Authors: Thomas W, Seidenspinner S, Kawczyńska-Leda N, Chmielnicka-Kopaczyk M, Marx A, Wirbelauer J, Szymankiewicz M, Speer CP Tags: Neonatology Source Type: journals

Quantitative Analysis of Amplitude-Integrated Electroencephalogram Patterns in Stable Preterm Infants, with Normal Neurological Development at One Year.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: To our knowledge, this is the first study where aEEG development was studied by automated quantification of aEEG characteristics in a cohort of stable preterm infants with a normal neurological development at 1 year of age. LMA and DC-% are simple quantitative measures of neurophysiologic development and may be used to evaluate neurodevelopment in infants. PMID: 19864923 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 28, 2009 Category: Perinatology & Neonatology Authors: Niemarkt HJ, Andriessen P, Peters CH, Pasman JW, Blanco CE, Zimmermann LJ, Bambang Oetomo S Tags: Neonatology Source Type: journals

Pulmonary Vascular Endothelial Growth Factor Expression and Disaturated Phospholipid Content in a Chicken Model of Hypoxia-Induced Fetal Growth Restriction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Both prenatal hypoxia and hyperoxia induced during critical windows of lung development differentially modulate surfactant synthesis. Our data support the concept that fetal oxygen tension is a key signal in the regulation of the surfactant system. PMID: 19864924 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 28, 2009 Category: Perinatology & Neonatology Authors: Been JV, Zoer B, Kloosterboer N, Kessels CG, Zimmermann LJ, van Iwaarden JF, Villamor E Tags: Neonatology Source Type: journals

Long-Chain Polyunsaturated Fatty Acid Composition of Breast Milk in Pre-Eclamptic Mothers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The data suggest that in pre-eclampsia, the relation between plasma and milk DHA is altered. The resulting higher milk DHA concentrations are beneficial for infants. PMID: 19864925 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 28, 2009 Category: Perinatology & Neonatology Authors: Dangat KD, Mehendale SS, Yadav HR, Kilari AS, Kulkarni AV, Taralekar VS, Joshi SR Tags: Neonatology Source Type: journals

Cerebral Amino Acid Profiles after Hypoxia-Reoxygenation and N-Acetylcysteine Treatment in the Newborn Piglet.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In newborn piglets that have sustained brain injury related to hypoxia/reoxygenation, the administration of NAC does not disrupt cerebral amino acid balance and maintains cerebral amino acid homeostasis. PMID: 19864926 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 28, 2009 Category: Perinatology & Neonatology Authors: Jantzie LL, Cheung PY, Johnson ST, Bigam DL, Todd KG Tags: Neonatology Source Type: journals

Maternal Alcohol Intake and Offspring Pulse Wave Velocity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Carotid-femoral PWV in adults is predictive of cardiovascular morbidity and mortality. The degree of continuity between childhood and adulthood PWV is unknown, but as we found an association between prenatal alcohol exposure and carotid-femoral PWV at 9 years, a permanent change in vessel wall structure or function is possible. These findings need to be confirmed in other and larger cohorts, and mechanistic animal studies are needed. PMID: 19864927 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - October 28, 2009 Category: Perinatology & Neonatology Authors: Morley R, Dwyer T, Hynes KL, Cochrane J, Ponsonby AL, Parkington HC, Carlin JB Tags: Neonatology Source Type: journals

Use of Procalcitonin-Guided Decision-Making to Shorten Antibiotic Therapy in Suspected Neonatal Early-Onset Sepsis: Prospective Randomized Intervention Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion:Serial PCT determinations allow to shorten the duration of antibiotic therapy in term and near-term infants with suspected early-onset sepsis. Before this PCT-guided strategy can be recommended, its safety has to be confirmed in a larger cohort of neonates. PMID: 19776651 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - September 23, 2009 Category: Perinatology & Neonatology Authors: Stocker M, Fontana M, El Helou S, Wegscheider K, Berger TM Tags: Neonatology Source Type: journals

Expression of Airway Epithelial Sodium Channel in the Preterm Infant Is Related to Respiratory Distress Syndrome but Unaffected by Repeat Antenatal beta-Methasone.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: A single repeat dose of antenatal beta-methasone did not increase ENaC expression, which may in part explain the absence of reduction in RDS incidence. PMID: 19776646 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - September 21, 2009 Category: Perinatology & Neonatology Authors: Janér C, Helve O, Pitkänen OM, Kari MA, Peltoniemi OM, Hallman M, Hovi P, Andersson S Tags: Neonatology Source Type: journals

Neonatal Period: Body Composition Changes in Breast-Fed Full-Term Newborns.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These results indicate that body composition changes are constituted by a reduction in both fat and fat free mass. However, a greater %FM is lost and consequently regained by day 5 when compared to fat-free mass. PMID: 19776647 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - September 21, 2009 Category: Perinatology & Neonatology Authors: Roggero P, Giannì ML, Orsi A, Piemontese P, Amato O, Moioli C, Mosca F Tags: Neonatology Source Type: journals

Perfluorocarbon Dosing when Starting Partial Liquid Ventilation: Haemodynamics and Cerebral Blood Flow in Preterm Lambs.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Preterm lambs receiving a dose of tracheal perfluorocarbon at the start of PLV have an increased cortical cerebral blood flow velocity, but no change in cortical cerebral blood flow variability. PMID: 19776648 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - September 21, 2009 Category: Perinatology & Neonatology Authors: Davies MW, Dunster KR, Wilson K, Colditz PB Tags: Neonatology Source Type: journals

Impact of Oxygen Saturation Targets and Oxygen Therapy during the Transport of Neonates with Clinically Suspected Congenital Heart Disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: If congenital heart disease is strongly suspected oxygen should be cautiously weaned to maintain a minimum SpO(2) >75%. Neonates receiving >70% oxygen are at greatest risk of metabolic acidosis or critical hypoxemia and may benefit from expedited transfer to a cardiac center. PMID: 19776649 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - September 21, 2009 Category: Perinatology & Neonatology Authors: Shivananda S, Kirsh J, Whyte HE, Muthalally K, McNamara PJ Tags: Neonatology Source Type: journals

The Oxygen Conundrum for Infants with Suspected Congenital Heart Disease. Commentary on S. Shivananda et al.: Impact of Oxygen Saturation Targets and Oxygen Therapy during the Transport of Neonates with Clinically Suspected Congenital Heart Disease (Neonatology 2010;97:154-162).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19776650 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - September 21, 2009 Category: Perinatology & Neonatology Authors: Schelonka RL, Carlo WA Tags: Neonatology Source Type: journals

Proceedings of the 24th International Workshop on Surfactant Replacement. Workshop dedicated in memory of Bengt Robertson. Ljubljana, Slovenia June 4-6, 2009.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19757515 [PubMed - indexed for MEDLINE] (Source: Neonatology)
Source: Neonatology - September 18, 2009 Category: Perinatology & Neonatology Tags: Neonatology Source Type: journals

Effect of Intermittent Hypercapnia on Respiratory Control in Rat Pups.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Preterm infants are subject to fluctuations in blood gas status associated with immature respiratory control. Intermittent hypoxia during early postnatal life has been shown to increase chemoreceptor sensitivity and destabilize the breathing pattern; however, intermittent hypercapnia remains poorly studied. Therefore, to test the hypothesis that intermittent hypercapnia results in altered respiratory control, we examined the effects of daily exposure to intermittent hypercapnia on the ventilatory response to subsequent hypercapnic and hypoxic exposure in neonatal rat pups. Exposure cycles consisted of 5 min of intermit...
Source: Neonatology - September 10, 2009 Category: Perinatology & Neonatology Authors: Steggerda JA, Mayer CA, Martin RJ, Wilson CG Tags: Neonatology Source Type: journals

Cardiac Output Measurement in Ventilated Lambs with a Significant Left-to-Right Shunt Using the Modified Carbon Dioxide Fick Method.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Cardiac output measurement with the mCO(2)F method is reliable and easily applicable in ventilated newborn lambs, also in the presence of a significant left-to-right shunt. PMID: 19752578 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - September 10, 2009 Category: Perinatology & Neonatology Authors: de Boode WP, Hopman JC, Wijnen MH, Tanke RB, van der Hoeven HG, Liem KD Tags: Neonatology Source Type: journals

Atrioventricular Valve Annulus Velocity and Acceleration during Global Hypoxia in Newborn Pigs - Assessment of Myocardial Function.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Tissue Doppler velocity in systole, diastole and acceleration during rapid ejection reflect hemodynamic changes in the neonatal myocardium during global hypoxia and recovery. S and pSac reflect systolic function, while E' correlates with tau and mirrors diastolic function. PMID: 19713716 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - August 27, 2009 Category: Perinatology & Neonatology Authors: Odland HH, Kro GA, Edvardsen T, Thaulow E, Saugstad OD Tags: Neonatology Source Type: journals

Transcriptional Control of Cytokine Release from Monocytes of the Newborn: Effects of Endogenous and Exogenous Interleukin-10 versus Dexamethasone.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: At therapeutic levels of DEX, monocyte release of PI cytokine was insensitive to DEX in comparison to IL-10. IL-10 or its mechanism of action could lead to new therapy for inflammatory disorders in the perinatal period. PMID: 19713717 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - August 27, 2009 Category: Perinatology & Neonatology Authors: Chusid LA, Pereira-Argenziano L, Miskolci V, Vancurova I, Davidson D Tags: Neonatology Source Type: journals

Much Ado about Nothing: Two Millenia of Controversy on Tongue-Tie.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Tongue-tie, or ankyloglossia, is poorly defined and involves a short, thick, fibrosed, or fixed lingual frenulum. Operative interventions were proposed already in Greek medicine. In the Middle Ages, competition arose between midwives, who used their nails to detach the frenulum, and surgeons, who were allowed to use instruments. During the last century, the justification for frenotomy shifted from improved language to enhanced feeding. Despite the high frequency of the intervention, little research has been performed on its benefit, which remains a controversial topic among different groups of health professionals. ...
Source: Neonatology - August 24, 2009 Category: Perinatology & Neonatology Authors: Obladen M Tags: Neonatology Source Type: journals

Severe Hypernatremia in an Extremely Low Birth Weight Infant with Subsequent Normal Neurological Development.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of an extremely low birth weight infant (520 g, 24+6 weeks of gestation) with severe hypernatremia of 199 mmol/l due to a failure in the preparation of an infusion on the 7th day of life. The infant subsequently showed no signs of central nervous system complications and no neurological symptoms due to this mishap so far. MRI scan performed after 4 months showed no evidence of cerebral complications including white matter injury. Even severe hypernatremia might not inevitably lead to central nervous system dysfunction and seizures in extremely low birth weight infants. PMID: 19707024 [PubMed - as sup...
Source: Neonatology - August 24, 2009 Category: Perinatology & Neonatology Authors: Sabir H, Stannigel H, Mayatepek E, Hoehn T Tags: Neonatology Source Type: journals

Probiotics Reduce the Risk of Necrotizing Enterocolitis in Preterm Infants: A Meta-Analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Enteral supplementation of probiotics reduces the risk of severe NEC and mortality in preterm infants. A large randomized controlled trial is required to investigate the benefit and safety profile of probiotics supplementation in ELBW infants. PMID: 19707025 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - August 24, 2009 Category: Perinatology & Neonatology Authors: Alfaleh K, Anabrees J, Bassler D Tags: Neonatology Source Type: journals

SNAP-II and SNAPPE-II and the Risk of Structural and Functional Brain Disorders in Extremely Low Gestational Age Newborns: The ELGAN Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The physiologic instability in the first 12 post-natal hours identified by illness severity scores conveys information about the risks of brain damage and neurodevelopmental dysfunctions. This risk information might reflect postnatal characteristics in the causal chain. On the other hand, high SNAP scores might be indicators of immaturity and vulnerability. PMID: 19672122 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - August 10, 2009 Category: Perinatology & Neonatology Authors: Dammann O, Naples M, Bednarek F, Shah B, Kuban KC, O'Shea TM, Paneth N, Allred EN, Leviton A Tags: Neonatology Source Type: journals

Gastric Emptying of Preterm Neonates Receiving Domperidone.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Domperidone significantly reduces gastric emptying in preterm neonates, and this may account for its effect in cases of disturbances related to gut motility. PMID: 19648772 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 30, 2009 Category: Perinatology & Neonatology Authors: Gounaris A, Costalos C, Varchalama E, Kokori F, Grivea IN, Konstantinidi K, Syrogiannopoulos GA Tags: Neonatology Source Type: journals

Non-Nutritive Sucking Habits in Sleeping Infants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This pilot study presents important data for sucking habits in pacifier users which may provide a basis for further investigations concerning the efficacy of pacifiers in SIDS prophylaxis. PMID: 19648773 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 30, 2009 Category: Perinatology & Neonatology Authors: Hanzer M, Zotter H, Sauseng W, Pichler G, Müller W, Kerbl R Tags: Neonatology Source Type: journals

Efficacy of Oral Sucrose in Infants of Methadone-Maintained Mothers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study found no differences in the pain responses of ME infants and non-exposed infants when given sucrose during heel lance procedures. PMID: 19648774 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 30, 2009 Category: Perinatology & Neonatology Authors: Marceau JR, Murray H, Nanan RK Tags: Neonatology Source Type: journals

Soluble Fas Antigen and Soluble Fas Ligand in Intrauterine Growth Restriction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Circulating maternal, as well as fetal sFas and sFasL concentrations do not differ between AGA controls and IUGR cases, irrespectively of the etiology of the latter. Furthermore, the results of this study imply an acceleration of Fas-FasL-mediated apoptosis during delivery and a respective decrease postpartum in both normal and IUGR pregnancies. PMID: 19590243 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 6, 2009 Category: Perinatology & Neonatology Authors: Briana DD, Baka S, Boutsikou M, Liosi S, Vraila VM, Gourgiotis D, Hassiakos D, Malamitsi-Puchner A Tags: Neonatology Source Type: journals

Effects of Lutein on Oxidative Stress in the Term Newborn: A Pilot Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Lutein administration in newborns increases the levels of BAP decreasing TH. The enhancement of antioxidant activity in plasma clearly results in protecting newborn from perinatal OS. These preliminary results, adding a new contribution in antioxidant strategies, strongly require to be confirmed by RCT. PMID: 19590244 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 6, 2009 Category: Perinatology & Neonatology Authors: Perrone S, Longini M, Marzocchi B, Picardi A, Bellieni CV, Proietti F, Rodriguez A, Turrisi G, Buonocore G Tags: Neonatology Source Type: journals

Evaluation of Urinary S100B Protein Level and Lactate/Creatinine Ratio for Early Diagnosis and Prognostic Prediction of Neonatal Hypoxic-Ischemic Encephalopathy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: These data suggest that early measurement of both S100B level and lactate/creatinine ratio in the urine of newborns with HIE is a practical convenient and sensitive way to improve diagnosis on the third day of life and prognostic prediction of HIE. PMID: 19590245 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 6, 2009 Category: Perinatology & Neonatology Authors: Liu L, Zheng CX, Peng SF, Zhou HY, Su ZY, He L, Ai T Tags: Neonatology Source Type: journals

Behavioural Effects of Near-Term Acute Fetal Hypoxia in a Small Precocial Animal, the Spiny Mouse (Acomys cahirinus).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We have previously developed a model of near-term intra-uterine hypoxia producing significant neonatal mortality (37%) in a small laboratory animal - the spiny mouse - which has precocial offspring at birth. The aim of the present study was to determine if this insult resulted in the appearance of behavioural abnormalities in those offspring which survived the hypoxic delivery. Behavioural tests assessed gait (using footprint patterns), motor coordination and balance on an accelerating rotarod, and spontaneous locomotion and exploration in an open field. We found that the near-term acute hypoxic episode produced a mild...
Source: Neonatology - July 6, 2009 Category: Perinatology & Neonatology Authors: Ireland Z, Dickinson H, Fleiss B, Hutton LC, Walker DW Tags: Neonatology Source Type: journals

The Neonatal European Study of Inhaled Steroids (NEUROSIS): An EU-Funded International Randomised Controlled Trial in Preterm Infants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19590247 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 6, 2009 Category: Perinatology & Neonatology Authors: Bassler D, Halliday HL, Plavka R, Hallman M, Shinwell ES, Jarreau PH, Carnielli V, van den Anker J, Schwab M, Poets CF Tags: Neonatology Source Type: journals

Polymorphisms in the Renin-Angiotensin System and Outcome of Very-Low-Birthweight Infants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Both known functional polymorphisms of the renin-angiotensin system do not seem to be associated with the outcome of VLBW infants. PMID: 19571582 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 1, 2009 Category: Perinatology & Neonatology Authors: Spiegler J, Gilhaus A, König IR, Kattner E, Vochem M, Küster H, Möller J, Müller D, Kribs A, Segerer H, Wieg C, Nikischin W, von der Wense A, Gebauer C, Herting E, Göpel W Tags: Neonatology Source Type: journals

Apparent Diffusion Coefficient on Magnetic Resonance Imaging in Pons and in Corona Radiata and Relation with the Neurophysiologic Measurement and the Outcome in Very Preterm Infants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This is the first study to report a relationship between ADC and BAEP measurements in the pons. The study may add to the current knowledge about the relation between postnatal clinical factors and diffusion-weighted imaging when evaluating the high-risk infants. PMID: 19571583 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 1, 2009 Category: Perinatology & Neonatology Authors: Kaukola T, Perhomaa M, Vainionpää L, Tolonen U, Jauhiainen J, Pääkkö E, Hallman M Tags: Neonatology Source Type: journals

Long-Term Trends in the Epidemiology of Neonatal Sepsis and Antibiotic Susceptibility of Causative Agents.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The incidence of early-onset sepsis mainly caused by GBS decreased. In contrast, the incidence of late-onset sepsis, predominantly caused by CONS, increased significantly. The incidence of fungal and yeast infections remained low. The majority of CONS blood isolates were susceptible for first-generation cephalosporins. PMID: 19571584 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 1, 2009 Category: Perinatology & Neonatology Authors: van den Hoogen A, Gerards LJ, Verboon-Maciolek MA, Fleer A, Krediet TG Tags: Neonatology Source Type: journals

Long-Term Epidemiology of Neonatal Sepsis: Benefits and Concerns. Commentary on van den Hoogen A, et al.: Long-Term Trends in the Epidemiology of Neonatal Sepsis and Antibiotic Susceptibility of Causative Agents (Neonatology 2010;97:22-28).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19571585 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - July 1, 2009 Category: Perinatology & Neonatology Authors: Sherman MP Tags: Neonatology Source Type: journals

Preface. Neonatology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19494554 [PubMed - in process] (Source: Neonatology)
Source: Neonatology - June 28, 2009 Category: Perinatology & Neonatology Authors: Babnik J, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP Tags: Neonatology Source Type: journals

Fetal monitoring during labor.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
For three decades, cardiotocography has been the basic technique for fetal surveillance during labor, but its impact on fetal well-being remains controversial. The benefits and disadvantages of fetal monitoring with cardiotocography during labor are reviewed. Special reference is made to the possible effect on the rate of neonatal seizures in newborns and their long-term outcome. PMID: 19494555 [PubMed - in process] (Source: Neonatology)
Source: Neonatology - June 28, 2009 Category: Perinatology & Neonatology Authors: Ingemarsson I Tags: Neonatology Source Type: journals