Nephrology Dialysis Transplantation This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Announcements
(Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Tags: Announcements Source Type: research

Cancer risk and mortality after kidney transplantation: a population-based study on differences between Danish centres using standard immunosuppression with and without glucocorticoids
Conclusions There was a tendency of a higher post-transplant cancer occurrence, but lower all-cause mortality, in the Danish transplantation centre that adhered to a standard steroid-free immunosuppressive protocol. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Engberg, H., Wehberg, S., Bistrup, C., Heaf, J., Sorensen, S. S., Thiesson, H. C., Hansen, J. M., Svensson, M., Green, A., Marckmann, P. Tags: Renal Transplantation Source Type: research

Immunologic outcome in elderly kidney transplant recipients: is it time for HLA-DR matching?
Conclusions In elderly KTR, HLA-DR mismatches are independent risk factors for TCMR and the development of all classes of de novo DSA, both of which significantly impair graft survival. Introduction of HLA-DR matching in elderly KTR might significantly improve immunologic and overall outcome. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Halleck, F., Khadzhynov, D., Liefeldt, L., Schrezenmeier, E., Lehner, L., Duerr, M., Schmidt, D., Bamoulid, J., Lachmann, N., Waiser, J., Budde, K., Staeck, O. Tags: Renal Transplantation Source Type: research

Atypical haemolytic uraemic syndrome and pregnancy: outcome with ongoing eculizumab
Conclusions Eculizumab therapy during pregnancy displayed no overt safety issues but did not appear to prevent HELLP syndrome or pre-eclampsia in these high-risk chronic kidney disease patients. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Servais, A., Devillard, N., Fremeaux-Bacchi, V., Hummel, A., Salomon, L., Contin-Bordes, C., Gomer, H., Legendre, C., Delmas, Y. Tags: Intra- and Extracorporeal Treatments of Kidney Failure Source Type: research

Permanent cardiac pacing in patients with end-stage renal disease undergoing dialysis
Conclusions Dialysis patients are at an increased risk of dysrhythmia requiring pacemaker implantation compared with the general population. The risks are not significantly different between HD and PD patients. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Wang, I.-K., Lin, K.-H., Lin, S.-Y., Lin, C.-L., Chang, C.-T., Yen, T.-H., Sung, F.-C. Tags: Intra- and Extracorporeal Treatments of Kidney Failure Source Type: research

Long-term outcomes of persistent disease and relapse in primary membranous nephropathy
Conclusions Our data strongly suggest that mortality in PMN is seen in patients with disease progression to CKD-5. Achieving remission is strongly associated with improved renal survival after first presentation and following relapse. We suggest that patients who achieve remission should be followed up in longer term, and better strategies to help improve outcomes are needed in clinical practice. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Kanigicherla, D. A. K., Short, C. D., Roberts, S. A., Hamilton, P., Nikam, M., Harris, S., Brenchley, P. E. C., Venning, M. C. Tags: Chronic Kidney Disease Source Type: research

Zoster vaccination is associated with a reduction of zoster in elderly patients with chronic kidney disease
Conclusions Zoster vaccine is effective against incident zoster in older individuals with CKD. Extra efforts are warranted to increase vaccine uptake in individuals with CKD given the known low uptake in these higher risk individuals. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Langan, S. M., Thomas, S. L., Smeeth, L., Margolis, D. J., Nitsch, D. Tags: Chronic Kidney Disease Source Type: research

Prevalence and recognition of chronic kidney disease in Stockholm healthcare
Conclusions An estimated 6% of the adult Stockholm population accessing healthcare has CKD, but the frequency of albuminuria testing, nephrology consultations and registration of CKD diagnoses was suboptimal despite universal care. Improving provider awareness and treatment of CKD could have a significant public health impact. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Gasparini, A., Evans, M., Coresh, J., Grams, M. E., Norin, O., Qureshi, A. R., Runesson, B., Barany, P., Ärnlöv, J., Jernberg, T., Wettermark, B., Elinder, C. G., Carrero, J.-J. Tags: Chronic Kidney Disease Source Type: research

Outcomes in patients with chronic kidney disease not on dialysis receiving extended dosing regimens of darbepoetin alfa: long-term results of the EXTEND observational cohort study
Conclusions Long-term, extended dosing of DA maintained Hb concentrations in patients already treated with an ESA and corrected and maintained Hb in ESA-naïve patients. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Galle, J.-C., Addison, J., Suranyi, M. G., Claes, K., Di Giulio, S., Guerin, A., Herlitz, H., Kiss, I., Farouk, M., Manamley, N., Wirnsberger, G., Winearls, C. Tags: Chronic Kidney Disease Source Type: research

Impaired vascular function contributes to exercise intolerance in chronic kidney disease
Conclusions Arterial stiffness contributes to the observed reduced aerobic capacity in predialysis CKD, independent of age, haemoglobin levels and endothelial function and represents a promising therapeutic target for improving exercise capacity in this population. Future work is required to elucidate why higher circulating levels of miR-146a and miR-150 are associated with impaired renal function and increased arterial stiffness. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Van Craenenbroeck, A. H., Van Craenenbroeck, E. M., Van Ackeren, K., Hoymans, V. Y., Verpooten, G. A., Vrints, C. J., Couttenye, M. M. Tags: Chronic Kidney Disease Source Type: research

Markers of kidney disease and risk of subclinical and clinical heart failure in African Americans: the Jackson Heart Study
Conclusions Among a community-based cohort of African Americans, lower eGFR and higher ACR were associated with higher LVM. Furthermore, higher urine ACR was associated with incident HF, which was not entirely explained by the presence of left ventricular disease. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Bansal, N., Katz, R., Himmelfarb, J., Afkarian, M., Kestenbaum, B., de Boer, I. H., Young, B. Tags: Chronic Kidney Disease Source Type: research

Prognostic implications of adding urine output to serum creatinine measurements for staging of acute kidney injury after major surgery: a cohort study
Conclusions Adding UO to SCr criteria substantially increases the apparent incidence of AKI on hospital wards and significantly changes the prognostic implications of AKI identification and staging. These measures should not be considered equivalent criteria in AKI staging. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Quan, S., Pannu, N., Wilson, T., Ball, C., Tan, Z., Tonelli, M., Hemmelgarn, B. R., Dixon, E., James, M. T. Tags: Acute Kidney Injury Source Type: research

Factors influencing withdrawal from dialysis: a national registry study
Conclusions Death following dialysis withdrawal is common. Factors important to physical independence—prior cerebrovascular disease and increasing age—are associated with withdrawal. When combined with clinician comments this study provides an insight into the clinical decline affecting patients and the complexity of this decision. Early recognition of those likely to withdraw may improve end of life care. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Findlay, M. D., Donaldson, K., Doyle, A., Fox, J. G., Khan, I., McDonald, J., Metcalfe, W., Peel, R. K., Shilliday, I., Spalding, E., Stewart, G. A., Traynor, J. P., Mackinnon, B., on behalf of the Scottish Renal Registry (SRR) Tags: BASIC SCIENCE Source Type: research

Genotypic and phenotypic predictors of inflammation in patients with chronic kidney disease
Conclusion These results indicate a larger involvement of hereditary factors in inflammation than might have been expected and suggest that inclusion of genotype features in risk assessment studies is critical. The RLS model demonstrates that inflammation in CKD is determined by an extensive panel of factors and may prove to be a suitable tool that could enable a much-needed multifactorial approach as opposed to the commonly utilized single-factor analysis. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Luttropp, K., Debowska, M., Lukaszuk, T., Bobrowski, L., Carrero, J. J., Qureshi, A. R., Stenvinkel, P., Lindholm, B., Waniewski, J., Nordfors, L. Tags: BASIC SCIENCE Source Type: research

Urinary soluble CD163 level reflects glomerular inflammation in human lupus nephritis
Conclusions Glomerular CD163+ macrophages are the predominant phenotype in the kidneys of lupus patients. These findings indicate that the u-sCD163 level can serve as a biomarker for macrophage-dependent glomerular inflammation in human LN. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 7, 2016 Category: Urology & Nephrology Authors: Endo, N., Tsuboi, N., Furuhashi, K., Shi, Y., Du, Q., Abe, T., Hori, M., Imaizumi, T., Kim, H., Katsuno, T., Ozaki, T., Kosugi, T., Matsuo, S., Maruyama, S. Tags: BASIC SCIENCE Source Type: research