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Indexemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Source Type: journals

Sudden Unexpected Death in Epilepsy (SUDEP): Update and Reflectionsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article addresses aspects of sudden unexpected death in epilepsy, reflecting on current knowledge and questions that need answers to quantify, monitor, and reduce risk. A brief overview is followed by a discussion of definitions, drug treatment, genetic susceptibility, mechanisms in relation to seizure monitoring units and supervision, with some suggestions for the way forward. (Source: Neurologic Clinics)
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Lina Nashef, Philippe Ryvlin Source Type: journals

Advances on the Genetics of Mendelian Idiopathic Epilepsiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Genetic factors play an increasingly recognized role in idiopathic epilepsies. Since 1995, positional cloning strategies in multi-generational families with autosomal dominant transmission have revealed 11 genes (KCNQ2, KCNQ3, CHRNA4, CHRNA2, CHRNB2, SCN1B, SCN1A, SCN2A, GABRG2, GABRA1, and LGI1) and numerous loci for febrile seizures and epilepsies. To date, all genes with the exception of LGI1 (leucine-rich glioma inactivated 1), encode neuronal ion channel or neurotransmitter receptor subunits. Molecular approaches have revealed great genetic heterogeneity, with the vast majority of genes remaining to be identified. One...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Stéphanie Baulac, Michel Baulac Source Type: journals

Therapeutic Brain Stimulation for Epilepsyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article concentrates on clinical studies of DBS for epilepsy. (Source: Neurologic Clinics)
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Juliana Lockman, Robert S. Fisher Source Type: journals

Localization in Epilepsyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Pharmacologic therapy represents the first line of treatment of epilepsy and is effective in most patients. However, about 20% to 30% of cases develop intractable seizures that cannot be controlled by medication alone. In such cases, surgical intervention is considered for therapeutic, often curative purposes. Dynamic spatiotemporal variability in the epileptic focus renders seizure localization a challenge to the clinician. Many diagnostic modalities have been developed to identify different aspects of the epileptic focus. Older techniques are being increasingly supplemented by a variety of anatomic and functional imaging...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Dimitris G. Placantonakis, Theodore H. Schwartz Source Type: journals

Identification of Pharmacoresistant Epilepsyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
There is no single definition of pharmacoresistant (intractable, refractory) epilepsy. Prospective identification of pharmacoresistance is complicated by the variability of its appearance across different types of epilepsy and the variability of seizure control within a given patient over time. Failure of informative trials of two appropriate antiepileptic drugs has been recommended as a threshold that should trigger referral for evaluation at a comprehensive epilepsy center. Maximizing seizure control is imperative for reducing the risks and consequences of epilepsy, including the cognitive and psychiatric comorbidities a...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Anne T. Berg Source Type: journals

Teratogenic Effects of Antiepileptic Medicationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
During the last few years epilepsy and pregnancy registries and other large scale observational studies have provided new information on the teratogenic effects of the most frequently used antiepileptic drugs (AEDs). The prevalence of major congenital malformations associated with exposure to carbamazepine or lamotrigine appears to be only marginally increased from the expected, while malformation rates with valproate have been reported to be 2 to 4 times higher. Recent studies also suggest that compared with carbamazepine, lamotrigine and phenytoin, exposure to valproate in utero may be associated with poorer postnatal co...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Torbjörn Tomson, Dina Battino Source Type: journals

Selection of Antiepileptic Drugs in Adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article explores the rationale for treatment selection in adults with epilepsy. (Source: Neurologic Clinics)
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Linda J. Stephen, Martin J. Brodie Source Type: journals

Hormonal Aspects of Epilepsyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The interactions between hormones, epilepsy, and the medications used to treat epilepsy are complex, with tri-directional interactions which affect both men and women in various ways. Abnormalities of baseline endocrine status occur more commonly in people with epilepsy, and are most often described for the sex steroid hormone axis. Common symptoms include sexual dysfunction, decreased fertility, premature menopause, and polycystic ovarian syndrome. Antiepileptic drugs (AEDs) and hormones have a bidirectional interaction, with a decrease in the efficacy of hormonal contraceptive agents with some AEDs and a decrease in the ...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Page B. Pennell Source Type: journals

Predicting Seizures: A Behavioral Approachemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reviews the clinical evidence for seizure prediction. The epilepsy cycle is considered, including the interictal, preictal, ictal, and postictal phases. Evidence suggesting that the preictal phase can sometimes be identified based on neurophysiologic signals, premonitory features, the presence of trigger factors, or self-report is discussed. Diary studies have shown that seizures are not randomly distributed in time and that a subgroup of persons with epilepsy can predict an impending seizure. Paper diary data and preliminary analysis of electronic diary data suggest that seizure prediction is feasible. (Sourc...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Sheryl R. Haut, Richard B. Lipton Source Type: journals

The Etiology of Psychogenic Non-Epileptic Seizures: Toward a Biopsychosocial Modelemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article summarizes current knowledge about the etiology of PNES. Through describing the interactions of predisposing, precipitating, perpetuating, and triggering factors, an integrated biopsychosocial model of a complex disorder is developed. PNES emerge as a dissociative response to a range of different stressors in vulnerable individuals. Once established, maintaining factors turn a temporary disturbance into a chronically disabling disorder. (Source: Neurologic Clinics)
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Markus Reuber Source Type: journals

The Emerging Architecture of Neuropsychological Impairment in Epilepsyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A new literature is now under way, one linking cognitive abnormalities directly to indices of structural, functional, metabolic, and other neurobiologic markers of cerebral integrity, independent of their association with clinical epilepsy characteristics. These trends are reviewed in this article. The focus is on temporal lobe epilepsy (TLE) as a model with which to address the core points because this form of localization-related epilepsy has been very carefully studied from both a cognitive and imaging standpoint. Some pertinent historical issues are touched on first, followed by more detailed reviews of the cognitive a...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Bruce P. Hermann, Jack J. Lin, Jana E. Jones, Michael Seidenberg Source Type: journals

Depression and Epilepsy: A Review of Multiple Facets of Their Close Relationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reviews these data, the clinical manifestations of depressive disorders in PWE, and their significant impact on the suicidal risk and quality of life. (Source: Neurologic Clinics)
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Andres M. Kanner Source Type: journals

Determinants of Quality of Life in People with Epilepsyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reviews evidence of quality of life (QOL) determinants in people affected by epilepsy, including detractors and promoters. Emerging factors of particular significance for QOL are highlighted, including seizure frequency, medication side effects, psychological comorbidity, and stigma and discrimination. This article also examines the role of resilience, interpreted in its widest sense, for promoting good QOL, even in the presence of poorly controlled seizures. The importance of addressing both clinical and wider psychosocial issues is highlighted and some possible directions for future research into QOL in epil...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Ann Jacoby, Dee Snape, Gus A. Baker Source Type: journals

Prefaceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The diagnosis and management of patients who have epilepsy have greatly evolved over recent years. This issue of Neurologic Clinics presents state-of-the-art reviews by renowned experts of critical issues that illustrate this evolution and underscore their importance in the care of patients. The first six papers focus on the interrelationships between seizures and psychological, neuropsychological, and hormonal factors. The next five papers discuss pharmacologic treatment selection, drug resistance, approaches to localizing seizure onset, and deep brain stimulation as a possible non-pharmacological intervention. The final ...
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Authors: Steven C. Schachter Source Type: journals

Forthcoming Pagesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Source Type: journals

Table of Contentsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - October 24, 2009 Category: Neurology Source Type: journals

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(Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Source Type: journals

Peripherally Induced Movement Disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Peripherally induced movement disorders may be defined as involuntary or abnormal movements triggered by trauma to the cranial or peripheral nerves or roots. Although patients often recall some history of trauma before the onset of a movement disorder, determining the true relationship of the disorder to the earlier trauma is often difficult. The pathophysiology of these disorders is reviewed. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Joseph Jankovic Source Type: journals

Psychogenic Movement Disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Psychogenic movement disorders (PMDs) represent a challenging dilemma for the treating neurologist. The terminology to classify this disorder is confusing and making the diagnosis is difficult. Once the diagnosis has been established, treatment options are limited, and the patient generally does not accept the diagnosis. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Elizabeth L. Peckham, Mark Hallett Source Type: journals

Restless Legs Syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Restless legs syndrome (RLS) affects many people. General population prevalence surveys usually range from 1% to 12%, but most European ancestry studies suggest 10%. The development of validated rating scales and standardized diagnostic criteria have vastly improved the quality of RLS treatment trials. Although multiple medications have shown outstanding efficacy, all of them are felt to provide only symptomatic relief, rather than any “curative” effect. Dopamine agonists are clearly the best investigated and probably the most effective treatments for RLS. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: William G. Ondo Source Type: journals

Pathophysiology and Treatment of Myoclonusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Myoclonus is defined as sudden, brief, shock-like, involuntary movements caused by muscular contractions or inhibitions. Etiologic classification organizes the myoclonus disorders and provides major categories of clinical presentation. However, classifying myoclonus according to its source provides insight about its pathophysiology. The best strategy for symptomatic treatment is derived from defining the pathophysiology by way of source physiologic classification. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: John N. Caviness Source Type: journals

Tourette Syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Tourette syndrome (TS) is a neuro-developmental disorder of childhood that is often associated with various psychiatric morbidities. Timely diagnosis and appropriate management can significantly impact psychosocial functioning. Morbidities may be a major source of disability, and may determine ultimate prognosis, although most children will experience significant improvement or resolution of symptoms by adulthood. Additional management considerations must be made in those with TS symptoms persisting into adulthood. The mainstay of therapy remains dopamine receptor blocking drugs, but new therapies are emerging. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Joohi Jimenez-Shahed Source Type: journals

Huntington Disease and Other Choreasemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Chorea is defined as a syndrome characterized by brief, abrupt involuntary movements resulting from a continuous flow of random muscle contractions. There are genetic and non-genetic causes of chorea. The most common genetic cause of chorea is Huntington's disease (HD). Non-genetic forms of chorea include vascular choreas, auto-immune choreas, metabolic and toxic choreas, and drug-induced choreas. This chapter provides an overview of clinical features, pathogenesis and management of HD, other important genetic causes of chorea, Sydenham's chorea, other autoimmune choreas and vascular choreas. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Francisco Cardoso Source Type: journals

Genetics and Treatment of Dystoniaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The torsion dystonias encompass a broad collection of etiologic subtypes, often divided into primary and secondary classes. Tremendous advances have been made in uncovering the genetic basis of dystonia, including discovery of a gene causing early onset primary torsion dystonia—a GAG deletion in exon 5 of the DYT1 gene that encodes torsinA. Although the exact function of torsinA remains elusive, evidence suggests aberrant localization and interaction of mutated protein; this may result in an abnormal response to stress or interference with cytoskeletal events and the development of neuronal brain pathways. Breakthroughs ...
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Cordelia S. Schwarz, Susan B. Bressman Source Type: journals

Tremor: Clinical Features, Pathophysiology, and Treatmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Tremor is not understood completely, and pharmacotherapy for all tremor disorders is inadequate. Fortunately, deep brain stimulation is effective for the most common and disabling tremor disorders. Our understanding of pathologic tremors has increased at an accelerating pace during the past 30 years, and this will hopefully lead to improved pharmacotherapy in the near future. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Rodger J. Elble Source Type: journals

Surgical Treatment of Movement Disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Surgical approaches are an important consideration in the management of many movement disorders, particularly for patients refractory to medications. In this article, we review the history, pathophysiology, risks and indications for surgical treatment. Summaries of case studies, case series and clinical trials performed using deep brain stimulation are provided for Parkinson's disease, dystonia, essential tremor and other movement disorders. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Benzi M. Kluger, Olga Klepitskaya, Michael S. Okun Source Type: journals

Medical Treatment of Parkinson Diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The cardinal characteristics of Parkinson disease (PD) include resting tremor, rigidity, and bradykinesia. Patients may also develop autonomic dysfunction, cognitive changes, psychiatric symptoms, sensory complaints, and sleep disturbances. The treatment of motor and non-motor symptoms of Parkinson disease is addressed in this article. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Mark Stacy Source Type: journals

Etiology and Pathogenesis of Parkinson Diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The etiology of Parkinson disease (PD) is multifactorial and is likely to involve different causes in different patients. Several different genes have been identified as causes of familial PD, including alpha-synuclein gene mutations and multiplications, and mutations of parkin, PINK1, DJ1, and LRRK2. The biochemical consequences of these mutations have served to reinforce the relevance of the pathways to pathogenesis previously characterized, for example, mitochondrial dysfunction, oxidative stress, and protein misfolding and aggregation. The recognition that glucocerebrosidase mutations represent a significant risk facto...
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Anthony H.V. Schapira Source Type: journals

Prefaceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Few neurologic disorders have attracted more attention from the scientific and lay communities than Parkinson disease and related neurodegenerative diseases. Advances in basic research into mechanisms of neuronal death, physiology of the basal ganglia, and biochemistry and pharmacology are now being translated into clinical practice. Despite extraordinary therapeutic advances during the recent past, Parkinson disease continues to be among the most common causes of disability, particularly among the elderly. In this issue of Neurologic Clinics, dedicated entirely to movement disorders, two articles, one by Dr. Schapira and...
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Authors: Joseph Jankovic Source Type: journals

Forthcoming Pagesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Source Type: journals

Table of Contentsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - July 31, 2009 Category: Neurology Source Type: journals

Indexemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Source Type: journals

Cost-Effectiveness of Vasectomy Reversalemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this era of cost-consciousness and containment, it is imperative to examine not only treatment outcomes but also cost of these treatments. With improvements of in vitro fertilization outcome and continued development of less-invasive sperm retrieval methods, physicians and couples must examine all options available after surgical sterilization. Vasectomy reversal remains the gold standard of treatment; however, certain situations may be present in which sperm acquisition/in vitro fertilization may be a better option. A physician's responsibility is to present all options with the pros and cons of each, including cost, t...
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Paul Robb, Jay I. Sandlow Source Type: journals

Factors Predicting Successful Microsurgical Vasectomy Reversalemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article systematically reviews each of these phases of decision-making and management. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Harris M. Nagler, Howard Jung Source Type: journals

Techniques for Vasectomy Reversalemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article details the contemporary preoperative preparation, microsurgical techniques, and postoperative care recommended for vasectomy reversal. The two-layer vasovasostomy and intussuscepted epididymovasostomy techniques are presented in detail. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Larry I. Lipshultz, Jon A. Rumohr, Richard C. Bennett Source Type: journals

History of Vasectomy Reversalemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vasectomy reversal has come a long way since the first anastomosis of the vas deferens and epididymis. Although its history is not as politically charged as that of vasectomy, the progress of reversal surgery has had its share of brilliant discoveries and missteps. In the early part of the twentieth century, vasovasostomy and vasoepididymostomy were esoteric procedures, but by the 1970s, a majority of urologists had some experience with reversal surgery. With the advent of microsurgical technique, reversal surgery has become once more a specialist's undertaking. The history of vasectomy reversal is an excellent case study ...
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Howard H. Kim, Marc Goldstein Source Type: journals

The Law and Vasectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article explores why the national court system has seen a steady influx of claims alleging practitioners' failure properly to perform vasectomy or ensure sterilization and the manner in which that influx has caused physicians to reassess their methods of practicing medicine in an increasingly litigious environment and make the appropriate and necessary accommodations. Through their experiences as medical malpractice litigators and through the analysis of reported cases, national jury verdicts, and insurance claims made and paid in lawsuits arising from claims regarding the performance of vasectomy, the authors enlight...
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Andrew I. Kaplan, Jay A. Rappaport Source Type: journals

Putative Health Risks Associated with Vasectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reviews the literature surrounding each of these purported health concerns. Because the ultimate findings have important ramifications for both informed consent of vasectomy patients and for public health, the reported health risks in question should be critically evaluated. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Tobias S. Köhler, Anees A. Fazili, Robert E. Brannigan Source Type: journals

Risks and Complications of Vasectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vasectomy is a safe and effective procedure for permanent contraception. Vasectomy is 30 times less likely to fail and 20 times less likely to have postoperative complications than its gynecologic counterpart. Complications from vasectomy are rare and minor in nature. Immediate risks include infection, hematoma, and pain. Complications seldom lead to hospitalization or aggressive medical management. Technique is surgeon dependent; however, certain techniques, such as fascial interposition, seem to decrease rates of vasectomy failure. Despite myriad vasectomy techniques, failure rates are less than those seen with tubal li...
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Christopher E. Adams, Moshe Wald Source Type: journals

Effectiveness of Vasectomy Techniquesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The effectiveness of various vasectomy techniques is reviewed, with a focus on methods used for vas occlusion. Spontaneous recanalization of the vas is more common than generally recognized and is often transient. Simple ligation and excision has an unacceptably high risk for failure. Techniques that include cautery seem to have a lower risk for failure than techniques that do not include cautery. There is insufficient evidence to recommend a particular standardized cautery technique, but adding fascial interposition to cautery seems to be associated with the lowest risk for failure. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: David C. Sokal, Michel Labrecque Source Type: journals

Techniques of Vasectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vasectomy remains a safe and effective method of contraception for men. Many variations in surgical technique currently are used by surgeons in the United States, each with its own benefits and drawbacks. Regardless of the surgical method used, the most important factor for successful vasectomy remains the experience and skill of the surgeon. The amount of evidence-based literature on the rationale for the different techniques for vasectomy remains limited. Careful study and innovation of vasectomy techniques will ensure that the most commonly performed urologic surgical procedure remain an excellent form of contraception ...
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Kevin S. Art, Ajay K. Nangia Source Type: journals

Demographics of Vasectomy—USA and Internationalemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vasectomy is safer, simpler, less expensive, and equally as effective as female sterilization—yet it remains one of the least known and least used methods of contraception. Worldwide, an estimated 33 million of married women ages 15 to 49 (less than 3%) rely on their partner's vasectomy for contraception. (Source: Neurologic Clinics)
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: John M. Pile, Mark A. Barone Source Type: journals

History of Vasectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vasectomy as a medical term is a misnomer because only part of the vas deferens is excised during the procedure. Vas deferens as an anatomic structure was not a subject of significant clinical and research interest until the nineteenth century. It is difficult to find another surgical procedure as simple as vasectomy that has sparked so much medical and social controversies for more than a century. Vasectomy is a historical, social, philosophic, medical, demographic, and legal phenomenon. It is not surprising that the history of this procedure combines not only a constant quest for ideal technique and better results but al...
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Yefim R. Sheynkin Source Type: journals

Prefaceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vasectomy is a safe and effective method of contraception that should be viewed as permanent. In the United States, it is employed by nearly 11% of all married couples and is performed on approximately one-half million men each year. Thus, vasectomies are carried out more often than any other urologic surgical procedure. Worldwide, however, far fewer vasectomies are performed than female sterilizations by tubal ligation, even though vasectomy is less expensive and is associated with less morbidity and mortality than tubal ligation. This apparent underutilization of a safe procedure is caused, in part, by concerns of men an...
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Authors: Jay I. Sandlow, Harris M. Nagler Source Type: journals

Forthcoming Issuesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Source Type: journals

Contentsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - July 30, 2009 Category: Neurology Source Type: journals

Indexemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurologic Clinics)
Source: Neurologic Clinics - May 1, 2009 Category: Neurology Source Type: journals

Advances in Bioadhesives, Tissue Sealants, and Hemostatic Agentsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reviews the unique features, mechanism of action, safety profile, and prototypical applications of the agents most commonly used in urologic surgery. (Source: Neurologic Clinics)
Source: Neurologic Clinics - May 1, 2009 Category: Neurology Authors: Jeffery C. Wheat, J. Stuart Wolf Source Type: journals

Miniature In Vivo Robotics and Novel Robotic Surgical Platformsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article discusses the current state of miniature robotics and novel robotic surgical platforms and the development of future robotic technology for general surgery and urology. (Source: Neurologic Clinics)
Source: Neurologic Clinics - May 1, 2009 Category: Neurology Authors: Bhavin C. Shah, Shelby L. Buettner, Amy C. Lehman, Shane M. Farritor, Dmitry Oleynikov Source Type: journals