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Invited Review: APOE at the interface of inflammation, neurodegeneration and pathological protein spread in Alzheimer's disease
In conclusion, this review highlights the importance of understanding the role of APOE in multiple important pathological mechanisms in AD. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 28, 2018 Category: Neurology Authors: M. Tzioras,
C. Davies,
A. Newman,
R. Jackson,
T. Spires ‐Jones Tags: Invited Review Source Type: research
Diagnostic potential of sarcoplasmic myxovirus resistance protein A expression in subsets of dermatomyositis
ConclusionsSarcoplasmic MxA expression is more sensitive than PFA and RIG ‐I expression for a pathological diagnosis of DM, regardless of the autoantibody‐related subgroup. In light of its high sensitivity and specificity, it may be considered a pathological hallmark of DMper se. Also, lack of MxA expression in ASS supports the idea that ASS is a distinct entity from DM. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 22, 2018 Category: Neurology Authors: A. Uruha,
Y. Allenbach,
J. ‐L. Charuel,
L. Musset,
A. Aussy,
O. Boyer,
K. Mariampillai,
O. Landon‐Cardinal,
C. Rasmussen,
L. Bolko,
T. Maisonobe,
S. Leonard‐Louis,
S. Suzuki,
I. Nishino,
W. Stenzel,
O. Benveniste Tags: Original Article Source Type: research
Age ‐associated changes in the blood‐brain barrier: comparative studies in human and mouse
Neuropathology and Applied Neurobiology, Volume 44, Issue 7, Page 747-748, December 2018. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 20, 2018 Category: Neurology Tags: Erratum Source Type: research
Issue Information
Neuropathology and Applied Neurobiology, Volume 44, Issue 7, Page 645-645, December 2018. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 20, 2018 Category: Neurology Tags: Issue Information Source Type: research
Aicardi ‐Goutières syndrome with muscle involvement in early infancy
Neuropathology and Applied Neurobiology, Volume 44, Issue 7, Page 737-742, December 2018. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 20, 2018 Category: Neurology Authors: N. Deigendesch,
S. Morales ‐Gonzalez,
B. Weschke,
H.‐H. Goebel,
M. Schuelke,
W. Stenzel Tags: Scientific Correspondence Source Type: research
Heterogeneity in α‐synuclein sub‐types and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease
ConclusionsTaken together, these findings suggest that DLB have elevated levels of insoluble pS129 ‐α‐syn, but that increased levels of aqueous soluble o‐α‐syn and detergent soluble pS129‐α‐syn are also observed in PD and AD, suggesting different changes to α‐syn across the spectrum of neurodegenerative proteopathies.This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 13, 2018 Category: Neurology Authors: Nishant N. Vaikath,
Daniel Erskine,
Christopher M. Morris,
Nour K. Majbour,
Kostas Vekrellis,
Jia ‐Yi. Li,
Omar M. A. El‐Agnaf Tags: Original Article Source Type: research
Fluid biomarkers for frontotemporal dementias
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 13, 2018 Category: Neurology Authors: Henrik Zetterberg,
John C. van Swieten,
Adam L. Boxer,
Jonathan D. Rohrer Tags: Annual Review Issue ‐ Review Source Type: research
APOE at the interface of inflammation, neurodegeneration and pathological protein spread in Alzheimer's disease
Neuropathology and Applied Neurobiology,Volume 0, Issue ja, -Not available-. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 5, 2018 Category: Neurology Authors: Makis Tzioras,
Caitlin Davies,
Anastasia Newman,
Rosemary Jackson,
Tara Spires ‐Jones Source Type: research
Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: analysis by myositis autoantibody and pathological features
Neuropathology and Applied Neurobiology,Volume 0, Issue ja, -Not available-. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 31, 2018 Category: Neurology Authors: Shireena A. Yasin,
Peter W. Schutz,
Claire T. Deakin,
Erdal Sag,
Hemlata Varsani,
Stefanie Simou,
Lucy R. Marshall,
Sarah L. Tansley,
Neil J. McHugh,
Janice L. Holton,
Lucy R. Wedderburn,
Thomas S. Jacques,
The UK Juvenile Dermatomyositis Rese Source Type: research
Does ALS ‐FUS without FUS mutation represent ALS‐FET? Report of three cases
Neuropathology and Applied Neurobiology,Volume 0, Issue ja, -Not available-. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 30, 2018 Category: Neurology Authors: Sergi Borrego ‐Écija,
Elena Cortés‐Vicente,
Laura Cervera‐Carles,
Jordi Clarimón,
Josep Gámez,
Jordi Batlle,
Gerda Ricken,
Laura Molina‐Porcel,
Iban Aldecoa,
Raquel Sánchez‐Valle,
Ricardo Rojas‐García,
Ellen Gelpi Source Type: research
Neuropathology of non ‐tau frontotemporal lobar degeneration
Neuropathology and Applied Neurobiology,Volume 0, Issue ja, -Not available-. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 25, 2018 Category: Neurology Authors: Manuela Neumann,
Ian R. A. Mackenzie Source Type: research
Baseline concentration of misfolded α‐synuclein aggregates in cerebrospinal fluid predicts risk of cognitive decline in Parkinson's disease
Neuropathology and Applied Neurobiology,Volume 0, Issue ja, -Not available-. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 22, 2018 Category: Neurology Authors: Hanbing Ning,
Qi Wu,
Dongyang Han,
Tingting Yao,
Jingyun Wang,
Wenquan Lu,
Shuai Lv,
Qiaoyu Jia,
Xin Li Source Type: research
Rapidly Progressive Amyotrophic Lateral Sclerosis is Associated with Microglial Reactivity and Small Heat Shock Protein Expression in Reactive Astrocytes
Neuropathology and Applied Neurobiology,Volume 0, Issue ja, -Not available-. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 22, 2018 Category: Neurology Authors: Rianne P. Gorter,
Jodie Stephenson,
Erik Nutma,
Jasper Anink,
Jenny C. de Jonge,
Wia Baron,
Marie ‐Christina Jahreiβ,
Jeroen A.M. Belien,
Johannes M. van Noort,
Caroline Mijnsbergen,
Eleonora Aronica,
Sandra Amor Source Type: research
Challenges in the histopathological classification of ganglioglioma and DNT: microscopic agreement studies and a preliminary genotype ‐phenotype analysis
Neuropathology and Applied Neurobiology,Volume 0, Issue ja, -Not available-. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 16, 2018 Category: Neurology Authors: Ingmar Bl ümcke,
Roland Coras,
Annika K Wefers,
David Capper,
Eleonora Aronica,
Albert Becker,
Mrinalini Honavar,
Thomas J. Stone,
Thomas S Jacques,
Hajime Miyata,
Angelika Mühlebner,
Jose Pimentel,
Figen Söylemezoğlu,
Maria Thom Source Type: research
Integrated molecular characterization of IDH ‐mutant glioblastomas
Neuropathology and Applied Neurobiology,Volume 0, Issue ja, -Not available-. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 16, 2018 Category: Neurology Authors: Andrey Korshunov,
Belen Casalini,
Lukas Chavez,
Thomas Hielscher,
Martin Sill,
Marina Ryzhova,
Tanvi Sharma,
Daniel Schrimpf,
Damian Stichel,
David Capper,
David E Reuss,
Dominik Sturm,
Oxana Absalyamova,
Andrey Golanov,
Sander Lambo,
Melan Source Type: research