Long term outcome after endovascular treatment for large ischemic core acute stroke is associated with hypoperfusion intensity ratio and onset-to-reperfusion time
ConclusionsHigher HIR and longer OTR time in large core stroke patients were independently associated with unfavorable three-month outcomes after EVT. (Source: Neurosurgical Review)
Source: Neurosurgical Review - April 23, 2024 Category: Neurosurgery Source Type: research
A light in the darkness: sodium fluorescein-assisted peripheral nerve sheath tumors resection – a comprehensive systematic review and single-arm meta-analysis
AbstractThe treatment for peripheral nerve sheath tumors (PNSTs) is based on surgical excision and the primary goal is to improve symptoms whilst preserving neurological function. In order to improve this technique, surgeons may use sodium fluorescein (SF) to help visualize the neoplasm and, consequently, facilitate its removal. Aiming to assess the efficacy of this emerging surgical strategy, we conducted a systematic review and single-arm meta-analysis. We conducted a systematic search on thePubMed,Embase, andWeb of Science databases, following thePRISMA guidelines. Studies without outcomes of interest, case series with ...
Source: Neurosurgical Review - April 23, 2024 Category: Neurosurgery Source Type: research
Elevated skull fractures: an institutional experience and individual participant data meta-analysis
In this study, we present the meta-analysis of outcomes and complications within this patient cohor t, offering a comprehensive synthesis of existing literature on this pathology. However, further investigation is imperative to provide higher-quality evidence and address lingering uncertainties in the classification and management of ESFs. (Source: Neurosurgical Review)
Source: Neurosurgical Review - April 23, 2024 Category: Neurosurgery Source Type: research
Imaging manifestations of papillary glioneuronal tumors
AbstractTo analyse the imaging findings of papillary glioneuronal tumors (PGNTs), in order to improve the accuracy of preoperative diagnosis of this tumor. The clinical and imaging manifestations of 36 cases of PGNT confirmed by pathology were analyzed retrospectively. A total of 17 males and 19 females, averaging 22.47 ( ± 11.23) years. Initial symptoms included epilepsy in ten, headache in seven, and others in 19 cases. 97.2% (35/36) of the lesions were located in the supratentorial area, and 80.5% (29/36) in the intraventricular or deep white matter adjacent to the lateral ventricles. Twenty-four of the lesions (66.7...
Source: Neurosurgical Review - April 23, 2024 Category: Neurosurgery Source Type: research
Spontaneous acute-onset conus medullaris or cauda equina syndrome: beware of spinal acute subdural hematoma
(Source: Neurosurgical Review)
Source: Neurosurgical Review - April 23, 2024 Category: Neurosurgery Source Type: research
Harnessing generative artificial intelligence for meningioma prediction: a correspondence
(Source: Neurosurgical Review)
Source: Neurosurgical Review - April 23, 2024 Category: Neurosurgery Source Type: research
Efficacy and utility of antifibrinolytics in pediatric spine surgery: a systematic review and network meta-analysis
AbstractAntifibrinolytics have gained increasing attention in minimizing blood loss and mitigating the risks associated with massive transfusions, including infection and coagulopathy in pediatric patients undergoing spine surgery. Nevertheless, the selection of optimal agent is still a matter of debate. We aim to review the utility of these agents and compare the efficacy of antifibrinolytics in pediatric and adolescent spine surgeries. A comprehensive search was performed in Scopus, Web of Science, and MEDLINE databases for relevant works. Studies providing quantitative data on predefined outcomes were included. Primary ...
Source: Neurosurgical Review - April 22, 2024 Category: Neurosurgery Source Type: research
Low surgical weight associated with ETV failure in pediatric hydrocephalus patients
In this study, younger patients experienced higher ETV failure rates, but multivariate regression found that weight was a more robust pr edictor of ETV failure than chronologic age or gestational age, with an optimal cutoff of 4.9 kg in our small cohort. Given the limited sample size, further study is needed to elucidate the independent role of weight as a peri-operative variable in determining ETV candidacy in young infants.Previous presentations: Poster Presentation, Congress of Neurological Surgeons. (Source: Neurosurgical Review)
Source: Neurosurgical Review - April 22, 2024 Category: Neurosurgery Source Type: research
The future of neurosurgery in India: challenges and opportunities for early career researchers
(Source: Neurosurgical Review)
Source: Neurosurgical Review - April 22, 2024 Category: Neurosurgery Source Type: research
Enhancing the quality of evidence, comparability, and reproducibility in brain arteriovenous malformations treated with open surgery research: a systematic review and proposal of a reporting guideline for surgical and clinical outcomes
This study aims to assess the quality of studies reporting clinical and surgical outcomes for bAVMs treated by open surgery and develop a reporting guideline checklist focusing on essential elements to ensure comparability and reproducibility. This is a systematic literature review that followed the PRISMA guidelines with the search inMedline,Embase, andWeb of Science databases, for studies published between January 1, 2018, and December 1, 2023. Included studies were scrutinized focusing on seven domains: (1) Assessment of How Studies Reported on the Baseline Characteristics of the Patient Sample; (2) Assessment and rep...
Source: Neurosurgical Review - April 21, 2024 Category: Neurosurgery Source Type: research
Letter to the editor: natural history and neuro-oncological approach in spinal gangliogliomas: a systematic review
(Source: Neurosurgical Review)
Source: Neurosurgical Review - April 20, 2024 Category: Neurosurgery Source Type: research
Short-term predictors of stereotactic radiosurgery outcome for untreated single non-small cell lung cancer brain metastases: a restrospective cohort study
AbstractStereotactic radiosurgery (SRS) is an option for brain metastases (BM) not eligible for surgical resection, however, predictors of SRS outcomes are poorly known. The aim of this study is to investigate predictors of SRS outcome in patients with BM secondary to non-small cell lung cancer (NSCLC). The secondary objective is to analyze the value of volumetric criteria in identifying BM progression. This retrospective cohort study included patients>18 years of age with a single untreated BM secondary to NSCLC. Demographic, clinical, and radiological data were assessed. The primary outcome was treatment failure, defi...
Source: Neurosurgical Review - April 19, 2024 Category: Neurosurgery Source Type: research
Surgical management of large lower cranial nerves schwannomas: long term results of a less aggressive resection strategy
AbstractIn an effort to reduce the high morbidity and life-threatening complications after radical resection in large schwannoma surgery, alternative strategies of nontotal resections have emerged. To evaluate the long term clinical and oncological outcome after lower cranial nerves (LCN) schwannoma surgery operated on with a cranial nerve-sparing technique. Single center retrospective cohort study of 8 consecutive patients harboring LCN schwannomas operated on between March 2005 and October 2021. The mean LCN schwannoma diameter was 33 mm (range 26–51). Seven patients (87,5%) underwent a modified retrosigmoid approach...
Source: Neurosurgical Review - April 19, 2024 Category: Neurosurgery Source Type: research
Volumetric segmentation in the context of posterior fossa-related pathologies: a systematic review
ConclusionsVarious forms of segmentation techniques have been used to assess posterior fossa volumes/pathologies and each has its advantages and disadvantages. We discuss these nuances and summarize the current state of literature in the context of posterior fossa-associated pathologies. (Source: Neurosurgical Review)
Source: Neurosurgical Review - April 19, 2024 Category: Neurosurgery Source Type: research
Nomogram-based geometric and hemodynamic parameters for predicting the growth of small untreated intracranial aneurysms
This study aimed to construct a nomogram for predicting the growth of small IAs based on geometric and hemodynamic parameters. We retrospectively collected the baseline and follow-up angiographic images (CTA/ MRA) of 96 small untreated saccular IAs, created patient-specific vascular models and performed computational fluid dynamics (CFD) simulations. Geometric and hemodynamic parameters were calculated. A stepwise Cox proportional hazards regression analysis was employed to construct a nomogram. IAs were stratified into low-, intermediate-, and high-risk groups based on the total points from the nomogram. Receiver operatin...
Source: Neurosurgical Review - April 18, 2024 Category: Neurosurgery Source Type: research
