Nonlinear Biomedical PhysicsThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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On managing complex adaptive systems motivated by biosystems application to infectionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Many attempts to control Complex adaptive systems (CAS) have failed. Here we try to learn from biosystems to derive some principles for CAS management. An application to managing infections is given. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - October 11, 2009 Category: Physics Authors: A HegaziA HashishE Ahmed Source Type: journals

Influence of very low doses of mediators on fungal laccase activity - nonlinearity beyond imaginationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Laccase, an enzyme responsible for aerobic transformations of natural phenolics, in industrial applications requires the presence of low-molecular substances known as mediators, which accelerate oxidation processes. However, the use of mediators is limited by their toxicity and the high costs of exploitation. The activation of extracellular laccase in growing fungal culture with highly diluted mediators, ABTS and HBT is described. Two high laccase-producing fungal strains, Trametes versicolor and Cerrena unicolor, were used in this study as a source of enzyme. Selected dilutions of the mediators significantly increased the...
Source: Nonlinear Biomedical Physics - September 3, 2009 Category: Physics Authors: Elzbieta MalarczykJanina Kochmanska-RdestAnna Jarosz-Wilkolazka Source Type: journals

Disturbed functional brain networks and neurocognitive function in low-grade glioma patients: a graph theoretical analysis of resting-state MEGEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: LGG patients display higher short- and long-distance synchronization within the theta band. Network analysis revealed changes (in particularly the theta, beta, and upper gamma band) suggesting disturbed network architecture. Moreover, correlations between network characteristics and neurocognitive performance were found, Widespread changes in the strength and spatial organization of brain networks may be responsible for cognitive dysfunction in glioma patients. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - August 22, 2009 Category: Physics Authors: Ingeborg BosmaJaap ReijneveldMartin KleinLinda DouwBob van DijkJan HeimansCornelis Stam Source Type: journals

Simulation study of autoregulation responses of peripheral circulation to systemic pulsatilityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This simulation study, though focused on a simple effect attaining TPR modulation due to pulsatility, suggests that non-linear autoregulation mechanisms cannot be overlooked in the analysis of the integrated behavior of the global cardiovascular system, including the arterial tree and the peripheral vascular bed. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - July 23, 2009 Category: Physics Authors: Federico AlettiEttore LanzaroneMaria Laura CostantinoGiuseppe Baselli Source Type: journals

Comparative study of nonlinear properties of EEG signals of normal persons and epileptic patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In this article, differences in characteristics for normal subjects with eyes open and closed, epileptic subjects during seizure and seizure free intervals have been shown mainly using Hurst exponent. The H shows that the brain activity of a normal man is uncorrelated in nature whereas, epileptic brain activity shows long range anticorrelation. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - July 19, 2009 Category: Physics Authors: Md NurujjamanRamesh NarayananA.N. Sekar Iyengar Source Type: journals

Comparative study of nonlinear properties of EEG signals of normal persons and epileptic patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In this article, differences in characteristics for normal subjects with eyes open and closed, epileptic subjects during seizure and seizure free intervals have been shown mainly using Hurst exponent. The H shows that the brain activity of a normal man is uncorrelated in nature whereas, epileptic brain activity shows long range anticorrelation. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - July 19, 2009 Category: Physics Authors: Md NurujjamanRamesh NarayananA.N. Sekar Iyengar Source Type: journals

Critical scale of propagation influences dynamics of waves in a model of excitable mediumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These results suggest that critical propagation of excitation waves determines conditions for transition to unstable rhythms in a way similar to unstable cardiac rhythms. Established conditions were suitably accurate regardless of rate dependent features and the magnitude of the slopes of restitution curves. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - July 8, 2009 Category: Physics Authors: Joseph StarobinChristopher DanfordVivek VaradarajanAndrei StarobinVladimir Polotski Source Type: journals

Comments on introducing the immune systemEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It is argued that by studying some design principles of the immune system ,e.g. nonlinearity and being a complex adaptive system, one can easily find some explanations of basic properties of the system e.g. memory and tolerance. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - June 10, 2009 Category: Physics Authors: E Ahmed Source Type: journals

Everything you wanted to ask about EEG but were afraid to get the right answerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We answer several important questions concerning EEG. We also shortly discuss importance of nonlinear methods of contemporary physics in EEG analysis. Basic definitions and explanation of fundamental concepts may be found in my previous publications in NBP. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - May 26, 2009 Category: Physics Authors: Wlodzimierz Klonowski Source Type: journals

Hilbert-Huang versus morlet wavelet transformation on mismatch negativity of children in uninterrupted sound paradigmEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Support to absence ratio of Hilbert-Huang Transformation on mismatch negativity meets the theoretical expectations, i.e., larger deviant elicits larger MMN. However, Morlet wavelet transformation does not. Thus, HHT seems more appropriate in analyzing event-related potentials in the time-frequency domain. HHT appears to evaluate ERPs more accurately and provide theoretically valid information of the brain responses. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - February 2, 2009 Category: Physics Authors: Fengyu Cong, Tuomo Sipola, Tinna Huttunen-Scott, Xiaonan Xu, Tapani Ristaniemi and Heikki Lyytinen Source Type: journals

Global behavior of epidemic transmission on heterogeneous networks via two distinct routesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the study of epidemic spreading two natural questions are: whether the spreading of epidemics on heterogenous networks have multiple routes, and whether the spreading of an epidemic is a local or global behavior? In this paper, we answer the above two questions by studying the SIS model on heterogenous networks, and give the global conditions for the endemic state when two distinct routes with uniform rate of infection are considered. The analytical results are also verified by numerical simulations. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - May 1, 2008 Category: Physics Authors: Haifeng Zhang, Michael Small and Xinchu Fu Source Type: journals

Force plate monitoring of human hemodynamicsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Monitoring of heart movements and pulse wave propagation may be used e.g. to estimate the aortic pulse wave velocity, which is widely accepted as an index of aortic stiffness with the application of predicting risk of heart disease in individuals. More extended analysis of the method is however needed to assess its possible clinical application. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - February 22, 2008 Category: Physics Authors: Jan Kříž and Petr Šeba Source Type: journals

Reconstruction of cellular variability from spatiotemporal patterns of Dictyostelium discoideumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Variability in cell properties can be an important driving mechanism behind spatiotemporal patterns in biological systems, as the degree of cell-to-cell differences determines the capacity of cells to locally synchronize and, consequently, form patterns on a larger spatial scale. In principle, certain features of spatial patterns emerging with time may be regulated by variability or, more specifically, by certain constellations of cell-to-cell differences. Similarly, measuring variability in a system (i.e. the spatial distribution of cell-cell differences) may help predict properties of later-stage patterns.Here we apply a...
Source: Nonlinear Biomedical Physics - August 30, 2007 Category: Physics Authors: Christiane Hilgardt, Stefan C Müller and Marc-Thorsten Hütt Source Type: journals

Developing combinatorial multi-component therapies (CMCT) of drugs that are more specific and have fewer side effects than traditional one drug therapiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Drugs designed for a specific target are always found to have multiple effects. Rather than hope that one bullet can be designed to hit only one target, nonlinear interactions across genomic and proteomic networks could be used to design Combinatorial Multi-Component Therapies (CMCT) that are more targeted with fewer side effects. We show here how computational approaches can be used to predict which combinations of drugs would produce the best effects. Using a nonlinear model of how the output effect depends on multiple input drugs, we show that an artificial neural network can accurately predict the effect of all 215 = 3...
Source: Nonlinear Biomedical Physics - August 30, 2007 Category: Physics Authors: Larry S Liebovitch, Nicholas Tsinoremas and Abhijit Pandya Source Type: journals

Bioactive peptide design using the Resonant Recognition ModelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study utilises the RRM computational approach to the analysis of oncogene and proto-oncogene proteins. The results obtained have shown that the RRM is capable of identifying the differences between the oncogenic and proto-oncogenic proteins with the possibility of identifying the "cancer-causing" features within their protein primary structure. In addition, the rational design of bioactive peptide analogues displaying oncogenic or proto-oncogenic-like activity is presented here. (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - July 19, 2007 Category: Physics Authors: Irena Cosic and Elena Pirogova Source Type: journals

Virtual respiratory system in investigation of CPAP influence on optimal breathing frequency in obstructive lungs diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The CPAP efficacy depends on the level of OLDMO. CPAP is efficient in the severe OLDMO because it increases the optimal BF, which makes possible less energy-consuming breathing with frequency close to the normal one (greater BF means smaller tidal volume and thus smaller work against lungs compliance). (Source: Nonlinear Biomedical Physics)
Source: Nonlinear Biomedical Physics - July 16, 2007 Category: Physics Authors: Tomasz Golczewski and Marek Darowski Source Type: journals

From conformons to human brains: an informal overview of nonlinear dynamics and its applications in biomedicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Methods of contemporary physics are increasingly important for biomedical research but, for a multitude of diverse reasons, most practitioners of biomedicine lack access to a comprehensive knowledge of these modern methodologies. This paper is an attempt to describe nonlinear dynamics and its methods in a way that could be read and understood by biomedical professionals who usually are not trained in advanced mathematics. After an overview of basic concepts and vocabulary of nonlinear dynamics, deterministic chaos, and fractals, application of nonlinear methods of biosignal analysis is discussed. In particular, five case ...
Source: Nonlinear Biomedical Physics - July 5, 2007 Category: Physics Authors: Wlodzimierz Klonowski Source Type: journals