Nutrition & Metabolism
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FcRn mediates elongated serum half-life of human IgG in cattle
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IgG has the longest survival time in the circulation of the Ig classes and the lowest fractional catabolic rate. The neonatal Fc receptor (FcRn) plays an important role in regulating these processes. Recently, we have cloned the bovine neonatal Fc receptor (bFcRn) alpha chain and detected its expression in various epithelial cells which are mediating IgG secretion. However, its function in IgG homeostasis has not been investigated. In the current study, we analyzed the binding affinity of bovine and human IgGs to bFcRn using surface plasmon resonance and by in vitro radioreceptor binding assays. As human IgG binds stronger...
Source: International Immunology - March 20, 2006 Category: Allergy & Immunology Authors: Kacskovics, I., Kis, Z., Mayer, B., West, A. P., Tiangco, N. E., Tilahun, M., Cervenak, L., Bjorkman, P. J., Goldsby, R. A., Szenci, O., Hammarstrom, L. Source Type: journals
CDC to Host First Diabetes and Obesity ConferenceEmail this article to a colleague.
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Diabetes and obesity have reached alarming rates in the United States. CDC’s Division of Diabetes Translation and the Division of Nutrition and Physical Activity are convening a national conference that will examine these issues and discuss ways to combat these illnesses through improving the environment, changing policies, building better health care systems, and helping individuals make lifestyle changes.
Source: Centers for Disease Control and Prevention - April 20, 2006 Category: American Health Source Type: organizations
Meeting #5: Nutrition Standards for Foods in SchoolsEmail this article to a colleague.
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Source: Institute of Medicine - All new Projects, Reports, Events and News items - May 19, 2006 Category: American Health Source Type: news
Improving Clinical Outcomes: Multidisciplinary Management, Metabolism, and MonitoringEmail this article to a colleague.
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(No abstract is available for this citation)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - June 1, 2005 Category: Anesthesiology Authors: Murkin, J. M. Source Type: journals
Myocardial Metabolism and Improved OutcomesAfter High Risk Heart SurgeryEmail this article to a colleague.
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The healthy heart relies primarily upon the oxidation of fatty acids for energy, with the remaining coming from the oxidation of glucose and lactate. Changes in energy requirements are met by altering the balance of fuels depending upon the hormonal milieu as well as upon the availability of oxygen and substrates. The use of carbohydrates for fuel is metabolically more efficient and may improve the coupling between glycolysis and pyruvate oxidation. Therefore, promoting a shift in metabolic fuel substrate use during times of reduced oxygen availability may represent a cardioprotective strategy. Subsequently, there has been...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - June 1, 2005 Category: Anesthesiology Authors: Keith, M., Errett, L. Source Type: journals
Glucose and Insulin Influences on Heart and Brain in Cardiac SurgeryEmail this article to a colleague.
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The elective global ischemia of on-pump coronary artery bypass surgery contributes to the incidence of postoperative mortality, complications, and use of resources. In addition to cardiopulmonary bypass and techniques for myocardial protection such as aortic cross clamp, ventricular fibrillation, and cardioplegia, the administration of systemic glucose-insulinpotassium (GIK) in the perioperative period may act as both a metabolic modulator and potential inodilator. GIK may therefore serve to protect the myocardium and promote adequate cardiac and hemodynamic performance that would improve patient recovery. Cell, tissue, an...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - June 1, 2005 Category: Anesthesiology Authors: Quinn, D. W., Pagano, D., Bonser, R. S. Source Type: journals
[Review Articles] Interpreting Disparate Responses to Cancer Therapy: The Role of Human Population GeneticsEmail this article to a colleague.
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Increasingly, investigators are recognizing differences in tumor biology, drug metabolism, toxicity, and therapeutic response among different patient populations receiving anticancer agents. These observations provide exciting opportunities to identify the factors most important for predicting individual variability in pharmacologically relevant phenotypes and consequently for personalizing the delivery of cancer therapy. Although pharmacogenomic differences may explain some of these disparities, rigorous investigation of both genetic and nongenetic differences is important to identify the variables most important for opti...
Source: Journal of Clinical Oncology - May 8, 2006 Category: Cancer & Oncology Authors: Maitland, DiRienzo, Ratain Source Type: journals
Preliminary evidence of differential relations between prefrontal cortex metabolism and sustained attention in depressed adults with bipolar disorder and healthy controlsEmail this article to a colleague.
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Bipolar Disorders Volume 8, Issue 3, Page 248-254, Jun 2006
Source: Bipolar Disorders - May 12, 2006 Category: Psychiatry Source Type: journals
Variation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumorsEmail this article to a colleague.
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Genes involved in phase I and phase II regulation of aromatic hydrocarbon-induced effects exhibit sequence variability that may mediate the risk of adult brain tumors. We evaluated associations between gene variants in CYP1A1, CYP1B1, GSTM3, EPHX1, and NQO1 and adult brain tumor incidence. Cases were patients with glioma (n = 489), meningioma (n = 197), or acoustic neuroma (n = 96) diagnosed from 1994 to 1998 at three U.S. hospitals. Controls were 799 patients admitted to the same hospitals for nonmalignant conditions. DNA was extracted from blood samples collected from 1277 subjects, and genotyping was conducted for CYP1A...
Source: Neuro-Oncology - April 5, 2006 Category: Cancer & Oncology Authors: De Roos, A. J., Rothman, N., Brown, M., Bell, D. A., Pittman, G. S., Shapiro, W. R., Selker, R. G., Fine, H. A., Black, P. M., Inskip, P. D. Source Type: journals
Systematic review: bisphosphonates and jaw osteonecrosisEmail this article to a colleague.
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There have been a number of literature reports in which bisphosphonate therapy has been associated with osteonecrosis of the jaw, and the FDA has issued warnings on the topic to healthcare professionals in the US. This review aims to summarise the available literature on this adverse effect.
The authors carried out a limited literature search (Medline / Pubmed plus citations from retrieved articles and conference abstracts only) to locate case reports and case series describing patients with bisphosphonate-associated osteonecrosis of the jaw. They briefly describe the actions of this group of drugs, and the potential adv...
Source: NeLM news - Cancer - May 16, 2006 Category: Cancer & Oncology Source Type: organizations
Sports-Formulated Jelly Beans To Be Studied For Effectiveness In Improving Exercise Performance And Warding Off Fatigue During ExerciseEmail this article to a colleague.
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Researchers from the UC Davis Sports Medicine Program and Nutrition Department are using competitive endurance athletes in a study that will compare the effectiveness of three different forms of carbohydrate supplementation - including sports-formulated jelly beans - versus plain water in warding off fatigue after prolonged exercise and effects on performance. [click link for full article]
Source: Complementary Medicine / Alternative Medicine News From Medical News Today - April 17, 2006 Category: Complementary Medicine Source Type: news
Clinical Trial Shows 96% Improvement In Pressure Ulcer Healing Among Nursing Home ResidentsEmail this article to a colleague.
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Medical Nutrition USA,Inc., (MDNU) announced today the results of a clinical trial on itsPro-Stat(R) modular protein supplement. In the first clinical trial of itskind, investigators found that the use of Pro-Stat(R), improves the healing ofpressure ulcers among long-term care residents by 96%. [click link for full article]
Source: Complementary Medicine / Alternative Medicine News From Medical News Today - March 11, 2006 Category: Complementary Medicine Source Type: news
[ORIGINAL ARTICLES] First year changes of myocardial lymphatic endothelial markers in heart transplant recipientsEmail this article to a colleague.
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Conclusion: Myocardial lymphatics show a significant change of endothelial phenotype after transplantation, as demonstrated by significant quantitative changes of lymphatic endothelial marker density. Patients with at least one rejection of ISHLT IIIa or higher had a significantly lower density of VEGFR-3 at 0.5 month after transplantation. The results of this study warrant further investigation on the impact of transplantation on the lymphatic endothelium. The cause–effect relation between rejection and lymphatic endothelium remains to be investigated.
Source: European Journal of Cardio-Thoracic Surgery - April 27, 2006 Category: Cardiovascular & Thoracic Surgery Authors: Geissler, H. J., Dashkevich, A., Fischer, U. M., Fries, J. W.U., Kuhn-Regnier, F., Addicks, K., Mehlhorn, U., Bloch, W. Source Type: journals
New Harvard Health Publications BookEmail this article to a colleague.
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High cholesterol affects approximately 50 million Americans and is a major risk factor for cardiovascular disease--an illness that half of all men and a third of all women will get at some time in their lives. As founder and chief of the Lipid Metabolism Unit at Massachusetts General Hospital and an associate professor of medicine at Harvard Medical School, Mason Freeman, MD, treats hundreds of patients each year and oversees cholesterol research. [click link for full article]
Source: Cholesterol News From Medical News Today - March 11, 2006 Category: Cardiology Source Type: news
Latebreakers: Drug approved for children with growth failureEmail this article to a colleague.
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The FDA has approved Tercica's Increlex (mecasermin [rDNA origin] injection) for the long-term
treatment of growth failure in children with severe primary IGF-1 (insulin-like growth factor-1) deficiency (IGFD)
or with growth hormone gene deletion who have developed neutralizing antibodies to growth hormone. Increlex is
identical to IGF-1, the natural hormone produced in the body that has a broad range of activity central to growth
and metabolism.
Source: Drug Topics - Latebreakers - May 19, 2006 Category: Drugs & Pharmacology Source Type: info
OBSERVATION: Angiokeratoma Corporis Diffusum in a Patient With No Recognizable Enzyme AbnormalitiesEmail this article to a colleague.
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Conclusion Angiokeratoma corporis diffusum without recognizable enzyme deficiencies appears to be a distinct clinical entity with a benign course.
Source: Archives of Dermatology - May 15, 2006 Category: Dermatology News Authors: Kelly, B., Kelly, E. Source Type: journals
Metabolism and effect of para-toluene-sulfonamide on rat liver microsomal cytochrome P450 from in vivo and in vitro studiesEmail this article to a colleague.
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Acta Pharmacologica Sinica Volume 27, Issue 5, Page 635-640, May 2006
Source: Acta Pharmacologica Sinica - May 3, 2006 Category: Drugs & Pharmacology Source Type: journals
Inhibition of NF-κB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)Email this article to a colleague.
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French maritime pine bark extract (Pycnogenol®) displays a variety of anti-inflammatory effects in vivo. Aim of this study was to determine whether human plasma after oral intake of Pycnogenol contains sufficient concentrations of active principles to inhibit key mediators of inflammation. Blood samples from seven healthy volunteers were obtained before and after five days administration of 200 mg Pycnogenol per day. Plasma samples statistically significantly inhibited matrix metalloproteinase 9 (MMP-9) release from human monocytes and NF-κB activation. Thus, we provide evidence that bioavailable active principles of Pyc...
Source: Journal of Inflammation - January 27, 2006 Category: Drugs & Pharmacology Authors: Tanja Grimm, Zuzana Chovanová, Jana Muchová, Katarína Sumegová, Anna Liptáková, Zdeňka Ďuračková and Petra Högger Source Type: journals
Human physiologically based pharmacokinetic model for ACE inhibitors: ramipril and ramiprilatEmail this article to a colleague.
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Conclusion:
If the in vitro plasma binding kinetics of the ACE inhibitor for the two binding sites are known, a unique PBPK model description of the Griensven et. al. experimental data can be obtained.
Source: BMC Clinical Pharmacology - January 6, 2006 Category: Drugs & Pharmacology Authors: David G Levitt and Rik C Schoemaker Source Type: journals
Fructose metabolism in the adult mouse optic nerve, a central white matter tractEmail this article to a colleague.
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Source: Journal of Cerebral Blood Flow - May 3, 2006 Category: Neurology Authors: Paul J Meakin
Maxine J Fowler
Alex J Rathbone
Lynne M Allen
Bruce R Ransom
David E Ray
Angus M Brown Source Type: journals
Estimation of oxygen metabolism in a rat model of permanent ischemia using positron emission tomography with injectable15O-O2Email this article to a colleague.
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Source: Journal of Cerebral Blood Flow - March 22, 2006 Category: Neurology Authors: Takashi Temma
Yasuhiro Magata
Yuji Kuge
Sayaka Shimonaka
Kohei Sano
Yumiko Katada
Hidekazu Kawashima
Takahiro Mukai
Hiroshi Watabe
Hidehiro Iida
Hideo Saji Source Type: journals
Cortical glutamate metabolism is enhanced in a genetic model of absence epilepsyEmail this article to a colleague.
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Source: Journal of Cerebral Blood Flow - March 15, 2006 Category: Neurology Authors: Torun M Melø
Ursula Sonnewald
Monique Touret
Astrid Nehlig Source Type: journals
Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement miceEmail this article to a colleague.
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Conclusions:
Our results suggest that LPS activation of innate immune response in TR APOE glia results in opposing outcomes from microglia and astrocytes as a result of TR APOE-dependent activation of p38MAPK or NF-kB signaling in these two cell types.
Source: Journal of Neuroinflammation - April 7, 2006 Category: Neurology Authors: Izumi Maezawa, Nobuyo Maeda, Thomas J Montine and Kathleen S Montine Source Type: journals
Sexually dimorphic gene expression that overlaps maturation of type II pneumonocytes in fetal mouse lungsEmail this article to a colleague.
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Conclusions:
Among these sexually dimorphic genes, some may be candidates for a role in lung maturation. Indeed, on GD 17.5, the sex difference in surfactant lipids correlates with the sex difference in pulmonary expression of apolipoprotein genes, which are involved in lipid transport. This suggests a role for these genes in the surge of surfactant synthesis. Our results would help to identify novel genes involved in the physiopathology of the respiratory distress of the neonates.
Source: Reproductive Biology and Endocrinology - May 4, 2006 Category: Endocrinology Authors: Marc Simard, Pierre R Provost and Yves Tremblay Source Type: journals
Low-Glycemic Index Carbohydrates: An Effective Behavioral Change for Glycemic Control and Weight Management in Patients With Type 1 and 2 DiabetesEmail this article to a colleague.
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Conclusions
Daily incorporation of low-GI carbohydrates in meal planning can be an
effective diabetes self-management strategy for glycemic control and weight
management. The documented responses to the subjects' conceptual and practical
knowledge of the GI confirm their acceptance of this approach as a permanent
behavioral lifestyle change and not a "diet." The positive results
of this study attest to what worked for these subjects, inviting diabetes
educators to consider offering low-GI dietary advice to their diabetes
patients.
Source: The Diabetes Educator - January 26, 2006 Category: Endocrinology Authors: Burani, J., Longo, P. J. Source Type: journals
American Dietetic Association Guide to Diabetes Medical Nutrition Therapy and EducationEmail this article to a colleague.
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(No abstract is available for this citation)
Source: The Diabetes Educator - November 15, 2005 Category: Endocrinology Authors: Daly, A. Source Type: journals
Barriers to Medical Nutrition Therapy in Black Women With Type 2 Diabetes MellitusEmail this article to a colleague.
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Conclusions
Culturally sensitive diabetes interventions are an effective way to
overcome some of the barriers to medical nutrition therapy. Feedback provided
by this survey sug-gests that identification of more affordable healthy food
resources in the community is necessary. In addition, access issues such as
transportation to grocery stores should be on the agenda for public policy
issues. Finally, alternate sites for nutrition education, such as a
supermarket forum, warrant further investigation.
Source: The Diabetes Educator - October 3, 2005 Category: Endocrinology Authors: Galasso, P., Amend, A., Melkus, G. D., Nelson, G. T. Source Type: journals
Nutrition and DietEmail this article to a colleague.
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(No abstract is available for this citation)
Source: The Diabetes Educator - October 3, 2005 Category: Endocrinology Source Type: journals
Agrarian diet and diseases of affluence – Do evolutionary novel dietary lectins cause leptin resistance?Email this article to a colleague.
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Background:
The global pattern of varying prevalence of diseases of affluence, such as obesity, cardiovascular disease and diabetes, suggests that some environmental factor specific to agrarian societies could initiate these diseases.Presentation of the hypothesisWe propose that a cereal-based diet could be such an environmental factor. Through previous studies in archaeology and molecular evolution we conclude that humans and the human leptin system are not specifically adapted to a cereal-based diet, and that leptin resistance associated with diseases of affluence could be a sign of insufficient adaptation to such a diet...
Source: BMC Endocrine Disorders - December 10, 2005 Category: Endocrinology Authors: Tommy Jönsson, Stefan Olsson, Bo Ahrén, Thorkild C Bøg-Hansen, Anita Dole and Staffan Lindeberg Source Type: journals
Association of CETP TaqI and APOE polymorphisms with type II diabetes mellitus in North Indians: a case control studyEmail this article to a colleague.
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Conclusion:
CETP TaqI B and APOE HhaI polymorphism may not be associated with type II diabetes mellitus in North Indian population, however CETP TaqI B polymorphism may be associated with hypertension along with T2DM.
Source: BMC Endocrine Disorders - July 1, 2005 Category: Endocrinology Authors: Manjusha Dixit, Sandeep Bhattacharya and Balraj Mittal Source Type: journals
How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptomeEmail this article to a colleague.
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IntroductionHerein, we expand our previous work on the effects of long chain polyunsaturated fatty acids (LC-PUFA) on the murine hepatic transcriptome using novel statistical and bioinformatic approaches for evaluating microarray data. The analyses focuses on key differences in the transcriptomic response that will influence metabolism following consumption of FUNG (rich in 20:4n6), FISH (rich in 20:5n3, 22:5n3, and 22:6n3) and COMB, the combination of the two.
Results:
Using a variance-stabilized F-statistic, 371 probe sets (out of 13K probe sets in the Affymetrix Mu11K chip set) were changed by dietary treatment (P
Source: Lipids in Health and Disease - April 20, 2006 Category: Lipidology Authors: Alvin Berger, Matthew A Roberts and Bruce Hoff Source Type: journals
Prevalence of self-reported hypercholesterolaemia and its relation to dietary habits, in Greek adults; a national nutrition & health surveyEmail this article to a colleague.
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Conclusion:
Hypercholesterolaemia seems to affect a large part of Greek population. It is hopeful that hypercholesterolaemics may have started adopting some more healthy nutritional behaviour compared to normocholesterolaemic ones.
Source: Lipids in Health and Disease - March 12, 2006 Category: Lipidology Authors: George A Milias, Demosthenes B Panagiotakos, Christos Pitsavos, Dimitra Xenaki, George Panagopoulos and Christodoulos Stefanadis Source Type: journals
Influence of liver cancer on lipid and lipoprotein metabolismEmail this article to a colleague.
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Liver plays a key role in the metabolism of plasma apolipoproteins, endogenous lipids and lipoproteins. Hepatocellular carcinoma (HCC) is one of the most common fatal malignant tumors in China and in other Southeast Asian countries. This has been attributed to the high incidence of hepatitis B infection. Hepatitis B proteins, such as the hepatitis B X protein (HBx) that is large hepatitis B surface protein could regulate transcription of many candidate genes for liver carcinogenesis. It has known that patients who suffered from acute hepatitis B could have lipid disorders such as decreased plasma level of high-density lipo...
Source: Lipids in Health and Disease - March 3, 2006 Category: Lipidology Authors: Jingting Jiang, Peter Nilsson-Ehle and Ning Xu Source Type: journals
Joslin-led Study Reveals New Findings On Insulin Signaling In The LiverEmail this article to a colleague.
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BOSTON -- Insulin uses two distinct mechanisms to control glucose and the metabolism of blood fats (lipids) in the liver, a new Joslin Diabetes Center-led study has discovered. [click link for full article]
Source: Diabetes News From Medical News Today - May 16, 2006 Category: Endocrinology Source Type: news
Ghrelin: A Player In Diabetes But Not Obesity?Email this article to a colleague.
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Ghrelin, a hormone long considered a key player in obesity, may instead take a major role in maintaining the balance between insulin and glucose and the development of diabetes, said Baylor College of Medicine researchers in a report in the current issue of the journal Cell Metabolism."Everybody has been pushing the connection between obesity and ghrelin," said Dr. Roy G. [click link for full article]
Source: Diabetes News From Medical News Today - May 14, 2006 Category: Endocrinology Source Type: news
Children And Young Adults With Diabetes Do Not Meet Nutrition RecommendationsEmail this article to a colleague.
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Fewer than half of children and young adults who took part in a national multi-center study of young people with diabetes meet current dietary recommendations for many nutrients, potentially making treatment and management of their diabetes much more difficult, according to researchers at the University of South Carolina and other institutions. [click link for full article]
Source: Diabetes News From Medical News Today - May 7, 2006 Category: Endocrinology Source Type: news
Do Testosterone Patches Help Women With Under-active Pituitary Glands?Email this article to a colleague.
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New research published today in The Journal of Clinical Endocrinology & Metabolism showed the first positive effect of testosterone on bone density, body composition and emotional, cognitive and behavioral function in women with low testosterone levels resulting from under-active pituitary glands. [click link for full article]
Source: Endocrinology News From Medical News Today - May 14, 2006 Category: Endocrinology Source Type: news
Resistant Starch and Soluble Fiber May Improve Glucose MetabolismEmail this article to a colleague.
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In a small randomized trial, soluble fiber had a greater effect on postprandial insulin response in women, whereas glucose reduction was greater after resistant starch. (CME)Medscape Medical News
Source: Medscape Diabetes Headlines - May 19, 2006 Category: Endocrinology Source Type: info
Decreased Regurgitation with a Soy Formula Containing Added Soy FiberEmail this article to a colleague.
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The objective of this randomized study was to determine if fiber-supplemented soy formula reduced regurgitation in young infants. We compared regurgitation in 179 infants randomly assigned cow’s milk-based (CM, 90) formula or soy formula with fiber (SF, 89). Initial daily incidence was similar (CM, 3.6; SF, 3.9 episodes), but significantly lower after 7 days on SF (CM, 3.4; SF, 2.3; p = 0.001). Less frequent regurgitation after 7 days on SF was sustained after 28 days (CM, 48%; SF, 31% of feedings; p = 0.001). Feeding SF effectively managed regurgitation while providing balanced nutrition without altering caloric dis...
Source: Clinical Pediatrics - January 1, 2006 Category: Pediatrics Authors: Ostrom, K. M., Jacobs, J. R., Merritt, R. J., Murray, R. D. Source Type: journals
Imbalance In The Lipid Content Of The Liver May Trigger Advance From Fatty Liver To Liver FailureEmail this article to a colleague.
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An imbalance in the lipid content of the liver appears to trigger the downward spiral that leads some with fatty liver disease to advance to full-blown liver failure, according to a new study in the May Cell Metabolism. [click link for full article]
Source: Liver Disease / Hepatitis News From Medical News Today - May 13, 2006 Category: Gastroenterology Source Type: news
[Book reviews] Manual of pediatric nutrition, 4th editionEmail this article to a colleague.
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(No abstract is available for this citation)
Source: Archives of Disease in Childhood - May 19, 2006 Category: Pediatrics Authors: Gupta, R Source Type: journals
Twin Labs Wants 2 Cases Dismissed Under Permanent InjunctionEmail this article to a colleague.
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NEW YORK - Twin Laboratories Inc. (TL) and GN Oldco Corp. (f/k/a General Nutrition Center, GN) on March 30 to dismiss two ephedra cases, arguing that they are barred by the permanent injunction related to the global settlement of approximately 70 ephedra cases (In Re: Ephedra Products Liability Litigation, MDL No. 1598; Chris Lonergan v. Twin Laboratories, Inc., No. 05CV04717; Ken Lilly v. Twin Laboratories, Inc., No. 05CV04699, S.D. N.Y.).
Full story on lexis.com
Source: LexisNexis® Mealey's™ Ephedra & PPA Legal News - May 19, 2006 Category: Medical Law Source Type: info
Psychiatric genetics - the new era: genetic research and some clinical implicationsEmail this article to a colleague.
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Impressive advances in the last decade have been made in the genetics and neuroscience of neuropsychiatric illness. Synergies between complex genetics, elaboration of intermediate phenotypes (Egan et al. (2004) Schizophrenia. London: Blackwell) and novel applications in neuroimaging (Bookheimer et al. (2000) N Engl J Med, 343, 450–456) are revealing the effects of positively associated disease alleles on aspects of neurological function. Genes such as NRG-1, DISC1, RGS4, COMT, PRODH, DTNBP1, G72, DAAO, GRM3 (Harrison and Weinberger (2005) Mol Psychiatry, 10, 40–68) and others have been implicated in schizophren...
Source: British Medical Bulletin - December 19, 2005 Category: Journals (General) Authors: Prathikanti, S., Weinberger, D. R. Source Type: journals
Shake a Leg: Here Comes Caffeinated PantyhoseEmail this article to a colleague.
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A British website is selling caffeinated pantyhose. Are they kidding? When we posted about caffeine inhalers on April Fool's Day, it was obviously a joke. This is less ... transparent: The way the tights work is that body heat releases caffeine microcapsules into the leg, thus promoting the metabolism to kick in and start fat burning. According to the makers, results should be apparent in about 1-4 weeks, but they do say they may not work for everyone. Even so, I think most women will be keen to give the "Slim Fit 20" caffeine tights a go. Costs are around £27 ... As others have pointed out: if caffeine does cause wei...
Source: Medgadget - May 19, 2006 Category: Technology Consultants Source Type: info
The Effect of Instituting a Prehospital-Discharge Newborn Bilirubin Screening Program in an 18-Hospital Health SystemEmail this article to a colleague.
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CONCLUSIONS. Initiating a program of bilirubin screening in a multihospital health system, coupled with evaluating the results using a percentile-based nomogram, reduced the proportion of neonates with significant hyperbilirubinemia and reduced the rate of hospital readmissions with jaundice.
Source: PEDIATRICS - May 1, 2006 Category: Pediatrics Authors: Eggert, L. D., Wiedmeier, S. E., Wilson, J., Christensen, R. D. Source Type: journals
Delayed Whole-Body Cooling to 33 or 35{degrees}C and the Development of Impaired Energy Generation Consequential to Transient Cerebral Hypoxia-Ischemia in the Newborn PigletEmail this article to a colleague.
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CONCLUSIONS. Whole-body hypothermia for 24 hours at either 35 or 33°C, commenced 2 hours after resuscitation, prolonged the NTP/EPP latent phase and reduced the overall secondary falls in mean PCr/Pi and NTP/EPP during 48 hours after HI. Reducing the temperature from 35 to 33°C neither increased mean PCr/Pi and NTP/EPP nor further lengthened the latent phase.
Source: PEDIATRICS - May 1, 2006 Category: Pediatrics Authors: O'Brien, F. E., Iwata, O., Thornton, J. S., Vita, E. D., Sellwood, M. W., Iwata, S., Sakata, Y. S., Charman, S., Ordidge, R., Cady, E. B., Wyatt, J. S., Robertson, N. J. Source Type: journals
Comprehensive Cost-Utility Analysis of Newborn Screening StrategiesEmail this article to a colleague.
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CONCLUSIONS. Newborn screening seems to be one of the rare health care interventions that is beneficial to patients and, in many cases, cost saving. Over the long term, funding comprehensive newborn screening programs is likely to save money for society.
Source: PEDIATRICS - May 1, 2006 Category: Pediatrics Authors: Carroll, A. E., Downs, S. M. Source Type: journals
Laparotomy Versus Peritoneal Drainage for Necrotizing Enterocolitis or Isolated Intestinal Perforation in Extremely Low Birth Weight Infants: Outcomes Through 18 Months Adjusted AgeEmail this article to a colleague.
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CONCLUSIONS. Drainage was commonly used, and outcome was poor. Our findings, particularly the risk-adjusted odds ratio favoring laparotomy for death or impairment, indicate the need for a large, multicenter clinical trial to assess the effect of the initial surgical therapy on outcome at ≥18 months.
Source: PEDIATRICS - April 3, 2006 Category: Pediatrics Authors: Blakely, M. L., Tyson, J. E., Lally, K. P., McDonald, S., Stoll, B. J., Stevenson, D. K., Poole, W. K., Jobe, A. H., Wright, L. L., Higgins, R. D., for the NICHD Neonatal Research Network Source Type: journals
Lower Breastfeeding Rates Persist Among the Special Supplemental Nutrition Program for Women, Infants, and Children Participants, 1978-2003Email this article to a colleague.
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CONCLUSIONS. Breastfeeding rates among WIC participants have lagged behind those of non-WIC mothers for the last 25 years. The Healthy People 2010 goals for breastfeeding will not be reached without intervention. Food package and programmatic changes are needed to make the incentives for breastfeeding greater for WIC participants.
Source: PEDIATRICS - April 3, 2006 Category: Pediatrics Authors: Ryan, A. S., Zhou, W. Source Type: journals
Tipping the Scales: Obese Children and Child Safety SeatsEmail this article to a colleague.
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CONCLUSIONS. This study determined that there is limited availability of child safety seat types for the ever-increasing number of obese young children. There are substantial numbers of children who weigh more than the upper weight limit for most currently available child safety seats. While we await reductions in the childhood obesity epidemic, options for maximizing the protection of obese children in automobiles must be identified.
Source: PEDIATRICS - April 3, 2006 Category: Pediatrics Authors: Trifiletti, L. B., Shields, W., Bishai, D., McDonald, E., Reynaud, F., Gielen, A. Source Type: journals
